Mesenchymal Stem Cells Overexpressing IFN-β Inhibit Breast Cancer Growth and Metastases through Stat3 Signaling in a Syngeneic Tumor Model

Cancer Microenvironment

Volumn 3, Issue 1, 2010, Pages 83-95

  Ling, Xiaoyang ^a   Marini, Frank ^a   Konopleva, Marina ^a   Schober, Wendy ^a   Shi, Yuexi ^a   Burks, Jared ^a   Clise Dwyer, Karen ^a   Wang, Rui Yu ^a   Zhang, Weiguo ^a   Yuan, Xiaoqing ^a   Lu, Hongbo ^a   Caldwell, Lisa ^a   Andreeff, Michael ^a  

^a UNIVERSITY OF TEXAS   (United States)

Author keywords

Breast cancer; Dendritic cell; IFN ; MSC; Stat3; T regulatory cell

Indexed keywords

BETA INTERFERON; GELATINASE A; MYC PROTEIN; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; STAT3 PROTEIN; TRANSCRIPTION FACTOR FOXP3;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; BREAST CANCER; CANCER INHIBITION; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL BASED GENE THERAPY; CELL MIGRATION; CONFERENCE PAPER; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; DOWN REGULATION; FEMALE; GENE OVEREXPRESSION; IMMUNOCOMPETENCE; ISOGRAFT; LIVER METASTASIS; LUNG METASTASIS; MESENCHYMAL STEM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; TUMOR MICROENVIRONMENT;

EID: 78649661852     PISSN: 18752292     EISSN: 18752284     Source Type: Journal    
DOI: 10.1007/s12307-010-0041-8     Document Type: Conference Paper

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