A novel ultrasensitive hybridization-based ELISA method for 2-methoxyphosphorothiolate microRNAs and its in vitro and in vivo application

AAPS Journal

Volumn 12, Issue 4, 2010, Pages 556-568

  Chan, Kenneth K ^a,b,c   Liu, Zhongfa ^a,b   Xie, Zhiliang ^a   Chiu, Ming ^a   Wang, Hongyan ^a,b   Chen, Ping ^a   Dunkerson, Sarah ^a   Chiu, Michael ^a   Liu, Shujun ^a   Triantafillou, Georgia ^a   Garzon, Ramiro ^a,b   Croce, Carlo M ^a,b   Byrd, John C ^a,b,c   Muthusamy, Natarajan ^a   Marcucci, Guido ^a,b,c  

^a OHIO STATE UNIVERSITY   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

2 MeOPSmiRNAs; ELISA; Pharmacokinetics; Quantification

Indexed keywords

2' METHOXYPHOSPHOROTHIOLATE ANTAGO MICRORNA 155; 2' METHOXYPHOSPHOROTHIOLATE MICRORNA 16 1; 2' METHOXYPHOSPHOROTHIOLATE MICRORNA 29B; MICRORNA; UNCLASSIFIED DRUG;

ACCURACY; ANIMAL CELL; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BONE MARROW; CELL CULTURE; CELL LYSATE; CONTROLLED STUDY; DISTRIBUTION VOLUME; DRUG CLEARANCE; DRUG HALF LIFE; DRUG STABILITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLUORESCENCE; GENETIC TRANSFECTION; HYBRIDIZATION; MAXIMUM PLASMA CONCENTRATION; MOUSE; NONHUMAN; SINGLE DRUG DOSE;

ANIMALS; DOWN-REGULATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; LIMIT OF DETECTION; MICE; MICE, INBRED C57BL; MICRORNAS; NUCLEIC ACID HYBRIDIZATION; PHOSPHOROTHIOATE OLIGONUCLEOTIDES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; UP-REGULATION;

EID: 78649658592     PISSN: 15507416     EISSN: None     Source Type: Journal    
DOI: 10.1208/s12248-010-9214-0     Document Type: Article

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