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Volumn 299, Issue 6, 2010, Pages

PECAM-1 regulates proangiogenic properties of endothelial cells through modulation of cell-cell and cell-matrix interactions

Author keywords

Adherens junctions; Angiogenesis; CD31; Endothelial nitric oxide synthase; Osteopontin; Retinal endothelial cells; Tenascin C; Thrombospondins

Indexed keywords

CD31 ANTIGEN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE;

EID: 78649649463     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00246.2010     Document Type: Article
Times cited : (72)

References (56)
  • 1
    • 0035425503 scopus 로고    scopus 로고
    • Nitric oxide synthases: Structure, function and inhibition
    • Alderton WK, Cooper CE, Knowles RG. Nitric oxide synthases: structure, function and inhibition. Biochem J 357: 593-615, 2001.
    • (2001) Biochem J , vol.357 , pp. 593-615
    • Alderton, W.K.1    Cooper, C.E.2    Knowles, R.G.3
  • 3
    • 44449095569 scopus 로고    scopus 로고
    • An alternatively spliced isoform of PECAM-1 is expressed at high levels in human and murine tissues, and suggests a novel role for the C-terminus of PECAM-1 in cytoprotective signaling
    • Bergom C, Paddock C, Gao C, Holyst T, Newman DK, Newman PJ. An alternatively spliced isoform of PECAM-1 is expressed at high levels in human and murine tissues, and suggests a novel role for the C-terminus of PECAM-1 in cytoprotective signaling. J Cell Sci 121: 1235-1242, 2008.
    • (2008) J Cell Sci , vol.121 , pp. 1235-1242
    • Bergom, C.1    Paddock, C.2    Gao, C.3    Holyst, T.4    Newman, D.K.5    Newman, P.J.6
  • 5
    • 54249128761 scopus 로고    scopus 로고
    • Regulation of angiogenesis: Apoptotic cues from the ECM
    • Cheresh DA, Stupack DG. Regulation of angiogenesis: apoptotic cues from the ECM. Oncogene 27: 6285-6298, 2008.
    • (2008) Oncogene , vol.27 , pp. 6285-6298
    • Cheresh, D.A.1    Stupack, D.G.2
  • 8
    • 39049098612 scopus 로고    scopus 로고
    • PECAM-1 isoform-specific functions in PECAM-1-deficient brain microvascular endothelial cells
    • DiMaio TA, Sheibani N. PECAM-1 isoform-specific functions in PECAM-1-deficient brain microvascular endothelial cells. Microvasc Res 75: 188-201, 2008.
    • (2008) Microvasc Res , vol.75 , pp. 188-201
    • DiMaio, T.A.1    Sheibani, N.2
  • 9
    • 39249085138 scopus 로고    scopus 로고
    • Attenuation of retinal vascular development and neovascularization in PECAM-1-deficient mice
    • Dimaio TA, Wang S, Huang Q, Scheef EA, Sorenson CM, Sheibani N. Attenuation of retinal vascular development and neovascularization in PECAM-1-deficient mice. Dev Biol 315: 72-88, 2008.
    • (2008) Dev Biol , vol.315 , pp. 72-88
    • Dimaio, T.A.1    Wang, S.2    Huang, Q.3    Scheef, E.A.4    Sorenson, C.M.5    Sheibani, N.6
  • 14
    • 27144465277 scopus 로고    scopus 로고
    • Role of PECAM-1 in the shear-stress-induced activation of Akt and the endothelial nitric oxide synthase (eNOS) in endothelial cells
    • Fleming I, Fisslthaler B, Dixit M, Busse R. Role of PECAM-1 in the shear-stress-induced activation of Akt and the endothelial nitric oxide synthase (eNOS) in endothelial cells. J Cell Sci 118: 4103-4111, 2005.
    • (2005) J Cell Sci , vol.118 , pp. 4103-4111
    • Fleming, I.1    Fisslthaler, B.2    Dixit, M.3    Busse, R.4
  • 17
    • 0037081823 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase activity is linked to its presence at cell-cell contacts
    • Govers R, Bevers L, de Bree P, Rabelink TJ. Endothelial nitric oxide synthase activity is linked to its presence at cell-cell contacts. Biochem J 361: 193-201, 2002.
    • (2002) Biochem J , vol.361 , pp. 193-201
    • Govers, R.1    Bevers, L.2    De Bree, P.3    Rabelink, T.J.4
  • 19
    • 0041709179 scopus 로고    scopus 로고
    • Platelet endothelial cell adhesion molecule-1 modulates endothelial cell motility through the small G-protein Rho
    • DOI 10.1096/fj.02-1040com
    • Gratzinger D, Canosa S, Engelhardt B, Madri JA. Platelet endothelial cell adhesion molecule-1 modulates endothelial cell motility through the small G-protein Rho. FASEB J 17: 1458-1469, 2003. (Pubitemid 36935661)
    • (2003) FASEB Journal , vol.17 , Issue.11 , pp. 1458-1469
    • Gratzinger, D.1    Canosa, S.2    Engelhardt, B.3    Madri, J.A.4
  • 20
    • 33745115094 scopus 로고    scopus 로고
    • ICAM-2 mediates neutrophil transmigration in vivo: Evidence for stimulus specificity and a role in PECAM-1-independent transmigration
    • Huang MT, Larbi KY, Scheiermann C, Woodfin A, Gerwin N, Haskard DO, Nourshargh S. ICAM-2 mediates neutrophil transmigration in vivo: evidence for stimulus specificity and a role in PECAM-1-independent transmigration. Blood 107: 4721-4727, 2006.
    • (2006) Blood , vol.107 , pp. 4721-4727
    • Huang, M.T.1    Larbi, K.Y.2    Scheiermann, C.3    Woodfin, A.4    Gerwin, N.5    Haskard, D.O.6    Nourshargh, S.7
  • 22
    • 34250702237 scopus 로고    scopus 로고
    • Cell-matrix adhesion in vascular development
    • Hynes RO. Cell-matrix adhesion in vascular development. J Thromb Haemost 5, Suppl 1: 32-40, 2007.
    • (2007) J Thromb Haemost , vol.5 , Issue.SUPPL. 1 , pp. 32-40
    • Hynes, R.O.1
  • 23
    • 70849099495 scopus 로고    scopus 로고
    • The extracellular matrix: Not just pretty fibrils
    • Hynes RO. The extracellular matrix: not just pretty fibrils. Science 326: 1216-1219, 2009.
    • (2009) Science , vol.326 , pp. 1216-1219
    • Hynes, R.O.1
  • 24
    • 0141867737 scopus 로고    scopus 로고
    • PECAM-1: Old friend, new partners
    • Ilan N, Madri JA. PECAM-1: old friend, new partners. Curr Opin Cell Biol 15: 515-524, 2003.
    • (2003) Curr Opin Cell Biol , vol.15 , pp. 515-524
    • Ilan, N.1    Madri, J.A.2
  • 25
    • 0028114122 scopus 로고
    • Organization of the gene for human platelet/endothelial cell adhesion molecule-1 shows alternatively spliced isoforms and a functionally complex cytoplasmic domain
    • Kirschbaum NE, Gumina RJ, Newman PJ. Organization of the gene for human platelet/endothelial cell adhesion molecule-1 shows alternatively spliced isoforms and a functionally complex cytoplasmic domain. Blood 84: 4028-4037, 1994.
    • (1994) Blood , vol.84 , pp. 4028-4037
    • Kirschbaum, N.E.1    Gumina, R.J.2    Newman, P.J.3
  • 26
    • 34447510033 scopus 로고    scopus 로고
    • PECAM-1 isoform-specific regulation of kidney endothelial cell migration and capillary morphogenesis
    • Kondo S, Scheef EA, Sheibani N, Sorenson CM. PECAM-1 isoform-specific regulation of kidney endothelial cell migration and capillary morphogenesis. Am J Physiol Cell Physiol 292: C2070-C2083, 2007.
    • (2007) Am J Physiol Cell Physiol , vol.292
    • Kondo, S.1    Scheef, E.A.2    Sheibani, N.3    Sorenson, C.M.4
  • 28
    • 33745952251 scopus 로고    scopus 로고
    • The multiple languages of endothelial cell-to-cell communication
    • Liebner S, Cavallaro U, Dejana E. The multiple languages of endothelial cell-to-cell communication. Arterioscler Thromb Vasc Biol 26: 1431-1438, 2006.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 1431-1438
    • Liebner, S.1    Cavallaro, U.2    Dejana, E.3
  • 30
    • 17644379624 scopus 로고    scopus 로고
    • N-cadherin acts upstream of VE-cadherin in controlling vascular morphogenesis
    • Luo Y, Radice GL. N-cadherin acts upstream of VE-cadherin in controlling vascular morphogenesis. J Cell Biol 169: 29-34, 2005.
    • (2005) J Cell Biol , vol.169 , pp. 29-34
    • Luo, Y.1    Radice, G.L.2
  • 31
    • 0038120892 scopus 로고    scopus 로고
    • Signal transduction pathways mediated by PECAM-1: New roles for an old molecule in platelet and vascular cell biology
    • Newman PJ, Newman DK. Signal transduction pathways mediated by PECAM-1: new roles for an old molecule in platelet and vascular cell biology. Arterioscler Thromb Vasc Biol 23: 953-964, 2003.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 953-964
    • Newman, P.J.1    Newman, D.K.2
  • 32
    • 4644269059 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate receptor regulation of N-cadherin mediates vascular stabilization
    • Paik JH, Skoura A, Chae SS, Cowan AE, Han DK, Proia RL, Hla T. Sphingosine 1-phosphate receptor regulation of N-cadherin mediates vascular stabilization. Genes Dev 18: 2392-2403, 2004.
    • (2004) Genes Dev , vol.18 , pp. 2392-2403
    • Paik, J.H.1    Skoura, A.2    Chae, S.S.3    Cowan, A.E.4    Han, D.K.5    Proia, R.L.6    Hla, T.7
  • 33
    • 10044282925 scopus 로고    scopus 로고
    • Polyoma virus middle-T-transformed PECAM-1 deficient mouse brain endothelial cells proliferate rapidly in culture and form hemangiomas in mice
    • Rothermel TA, Engelhardt B, Sheibani N. Polyoma virus middle-T-transformed PECAM-1 deficient mouse brain endothelial cells proliferate rapidly in culture and form hemangiomas in mice. J Cell Physiol 202: 230-239, 2005.
    • (2005) J Cell Physiol , vol.202 , pp. 230-239
    • Rothermel, T.A.1    Engelhardt, B.2    Sheibani, N.3
  • 34
    • 50949116343 scopus 로고    scopus 로고
    • Homotypic and endothelial cell adhesions via N-cadherin determine polarity and regulate migration of vascular smooth muscle cells
    • Sabatini PJB, Zhang M, Silverman-Gavrila R, Bendeck MP, Langille BL. Homotypic and endothelial cell adhesions via N-cadherin determine polarity and regulate migration of vascular smooth muscle cells. Circ Res 103: 405-412, 2008.
    • (2008) Circ Res , vol.103 , pp. 405-412
    • Sabatini, P.J.B.1    Zhang, M.2    Silverman-Gavrila, R.3    Bendeck, M.P.4    Langille, B.L.5
  • 35
    • 0024536715 scopus 로고
    • Ultrastructural immunocytochemical localization of fibronectin deposition during corneal endothelial wound repair. Evidence for cytoskeletal involvement
    • Sabet MD, Gordon SR. Ultrastructural immunocytochemical localization of fibronectin deposition during corneal endothelial wound repair. Evidence for cytoskeletal involvement. Biol Cell 65: 171-179, 1989.
    • (1989) Biol Cell , vol.65 , pp. 171-179
    • Sabet, M.D.1    Gordon, S.R.2
  • 36
    • 18844362885 scopus 로고    scopus 로고
    • Regulation of endothelial derived nitric oxide in health and disease
    • Sessa WC. Regulation of endothelial derived nitric oxide in health and disease. Mem Inst Oswaldo Cruz 100, Suppl 1: 15-18, 2005.
    • (2005) Mem Inst Oswaldo Cruz , vol.100 , Issue.SUPPL. 1 , pp. 15-18
    • Sessa, W.C.1
  • 37
    • 0031941107 scopus 로고    scopus 로고
    • Down-regulation of platelet endothelial cell adhesion molecule-1 results in thrombospondin-1 expression and concerted regulation of endothelial cell phenotype
    • Sheibani N, Frazier WA. Down-regulation of platelet endothelial cell adhesion molecule-1 results in thrombospondin-1 expression and concerted regulation of endothelial cell phenotype. Mol Biol Cell 9: 701-713, 1998.
    • (1998) Mol Biol Cell , vol.9 , pp. 701-713
    • Sheibani, N.1    Frazier, W.A.2
  • 38
    • 0032968510 scopus 로고    scopus 로고
    • Thrombospondin-1, PECAM-1, and regulation of angiogenesis
    • Sheibani N, Frazier WA. Thrombospondin-1, PECAM-1, and regulation of angiogenesis. Histol Histopathol 14: 285-294, 1999.
    • (1999) Histol Histopathol , vol.14 , pp. 285-294
    • Sheibani, N.1    Frazier, W.A.2
  • 39
    • 0033840776 scopus 로고    scopus 로고
    • Differential modulation of cadherin-mediated cell-cell adhesion by platelet endothelial cell adhesion molecule-1 isoforms through activation of extracellular regulated kinases
    • Sheibani N, Sorenson CM, Frazier WA. Differential modulation of cadherin-mediated cell-cell adhesion by platelet endothelial cell adhesion molecule-1 isoforms through activation of extracellular regulated kinases. Mol Biol Cell 11: 2793-2802, 2000.
    • (2000) Mol Biol Cell , vol.11 , pp. 2793-2802
    • Sheibani, N.1    Sorenson, C.M.2    Frazier, W.A.3
  • 40
    • 0032959158 scopus 로고    scopus 로고
    • Tissue specific expression of alternatively spliced murine PECAM-1 isoforms
    • Sheibani N, Sorenson CM, Frazier WA. Tissue specific expression of alternatively spliced murine PECAM-1 isoforms. Dev Dyn 214: 44-54, 1999.
    • (1999) Dev Dyn , vol.214 , pp. 44-54
    • Sheibani, N.1    Sorenson, C.M.2    Frazier, W.A.3
  • 42
    • 0037370631 scopus 로고    scopus 로고
    • Lack of platelet endothelial cell adhesion molecule-1 attenuates foreign body inflammation because of decreased angiogenesis
    • Solowiej A, Biswas P, Graesser D, Madri JA. Lack of platelet endothelial cell adhesion molecule-1 attenuates foreign body inflammation because of decreased angiogenesis. Am J Pathol 162: 953-962, 2003.
    • (2003) Am J Pathol , vol.162 , pp. 953-962
    • Solowiej, A.1    Biswas, P.2    Graesser, D.3    Madri, J.A.4
  • 43
    • 0037646838 scopus 로고    scopus 로고
    • Isolation and characterization of murine retinal endothelial cells
    • Su X, Sorenson CM, Sheibani N. Isolation and characterization of murine retinal endothelial cells. Mol Vis 9: 171-178, 2003. (Pubitemid 38097583)
    • (2003) Molecular Vision , vol.9 , pp. 171-178
    • Su, X.1    Sorenson, C.M.2    Sheibani, N.3
  • 44
    • 77749292051 scopus 로고    scopus 로고
    • CYP1B1 and endothelial nitric oxide synthase combine to sustain proangiogenic functions of endothelial cells under hyperoxic stress
    • Tang Y, Scheef EA, Gurel Z, Sorenson CM, Jefcoate CR, Sheibani N. CYP1B1 and endothelial nitric oxide synthase combine to sustain proangiogenic functions of endothelial cells under hyperoxic stress. Am J Physiol Cell Physiol 298: C665-C678, 2010.
    • (2010) Am J Physiol Cell Physiol , vol.298
    • Tang, Y.1    Scheef, E.A.2    Gurel, Z.3    Sorenson, C.M.4    Jefcoate, C.R.5    Sheibani, N.6
  • 45
    • 60249103007 scopus 로고    scopus 로고
    • CYP1B1 expression promotes the proangiogenic phenotype of endothelium through decreased intracellular oxidative stress and thrombospondin-2 expression
    • Tang Y, Scheef EA, Wang S, Sorenson CM, Marcus CB, Jefcoate CR, Sheibani N. CYP1B1 expression promotes the proangiogenic phenotype of endothelium through decreased intracellular oxidative stress and thrombospondin-2 expression. Blood 113: 744-754, 2009.
    • (2009) Blood , vol.113 , pp. 744-754
    • Tang, Y.1    Scheef, E.A.2    Wang, S.3    Sorenson, C.M.4    Marcus, C.B.5    Jefcoate, C.R.6    Sheibani, N.7
  • 46
    • 0035869397 scopus 로고    scopus 로고
    • Platelet-endothelial cell adhesion molecule-1 (PECAM-1)-deficient mice demonstrate a transient and cytokine-specific role for PECAM-1 in leukocyte migration through the perivascular basement membrane
    • Thompson RD, Noble KE, Larbi KY, Dewar A, Duncan GS, Mak TW, Nourshargh S. Platelet-endothelial cell adhesion molecule-1 (PECAM-1)-deficient mice demonstrate a transient and cytokine-specific role for PECAM-1 in leukocyte migration through the perivascular basement membrane. Blood 97: 1854-1860, 2001.
    • (2001) Blood , vol.97 , pp. 1854-1860
    • Thompson, R.D.1    Noble, K.E.2    Larbi, K.Y.3    Dewar, A.4    Duncan, G.S.5    Mak, T.W.6    Nourshargh, S.7
  • 47
    • 0025992031 scopus 로고
    • The distribution of J1/tenascin and its transcript during the development of the avian cornea
    • Tucker RP. The distribution of J1/tenascin and its transcript during the development of the avian cornea. Differentiation 48: 59-66, 1991.
    • (1991) Differentiation , vol.48 , pp. 59-66
    • Tucker, R.P.1
  • 48
    • 1442354183 scopus 로고    scopus 로고
    • Expression pattern of alternatively spliced PECAM-1 isoforms in retinal vasculature
    • Wang Y, Repyak K, Sheibani N. Expression pattern of alternatively spliced PECAM-1 isoforms in retinal vasculature. Mol Vis 10: 103-111, 2004.
    • (2004) Mol Vis , vol.10 , pp. 103-111
    • Wang, Y.1    Repyak, K.2    Sheibani, N.3
  • 49
    • 0036031889 scopus 로고    scopus 로고
    • Expression pattern of alternatively spliced PECAM-1ba isoforms in hematopoietic cells and platelets
    • Wang Y, Sheibani N. Expression pattern of alternatively spliced PECAM-1ba isoforms in hematopoietic cells and platelets. J Cell Biochem 87: 424-438, 2002.
    • (2002) J Cell Biochem , vol.87 , pp. 424-438
    • Wang, Y.1    Sheibani, N.2
  • 50
    • 33646136466 scopus 로고    scopus 로고
    • PECAM-1 isoform-specific activation of MAPK/ERKs and small GTPases: Implications in inflammation and angiogenesis
    • Wang Y, Sheibani N. PECAM-1 isoform-specific activation of MAPK/ERKs and small GTPases: implications in inflammation and angiogenesis. J Cell Biochem 98: 451-468, 2006.
    • (2006) J Cell Biochem , vol.98 , pp. 451-468
    • Wang, Y.1    Sheibani, N.2
  • 51
    • 0037376250 scopus 로고    scopus 로고
    • Modulation of PECAM-1 expression and alternative splicing during differentiation and activation of hematopoietic cells
    • Wang Y, Su X, Sorenson CM, Sheibani N. Modulation of PECAM-1 expression and alternative splicing during differentiation and activation of hematopoietic cells. J Cell Biochem 88: 1012-1024, 2003.
    • (2003) J Cell Biochem , vol.88 , pp. 1012-1024
    • Wang, Y.1    Su, X.2    Sorenson, C.M.3    Sheibani, N.4
  • 52
  • 53
    • 20144383295 scopus 로고    scopus 로고
    • Thrombospondin-1 deficient mice exhibit an altered expression pattern of alternatively spliced PECAM-1 isoforms in retinal vasculature and endothelial cells
    • Wang Y, Su X, Wu Z, Sheibani N. Thrombospondin-1 deficient mice exhibit an altered expression pattern of alternatively spliced PECAM-1 isoforms in retinal vasculature and endothelial cells. J Cell Physiol 204: 352-361, 2005.
    • (2005) J Cell Physiol , vol.204 , pp. 352-361
    • Wang, Y.1    Su, X.2    Wu, Z.3    Sheibani, N.4
  • 54
    • 33646922275 scopus 로고    scopus 로고
    • Enhanced proangiogenic signaling in thrombospondin-1-deficient retinal endothelial cells
    • Wang Y, Wang S, Sheibani N. Enhanced proangiogenic signaling in thrombospondin-1-deficient retinal endothelial cells. Microvasc Res 71: 143-151, 2006.
    • (2006) Microvasc Res , vol.71 , pp. 143-151
    • Wang, Y.1    Wang, S.2    Sheibani, N.3
  • 55
    • 0042320953 scopus 로고    scopus 로고
    • Modulation of VE-cadherin and PECAM-1 mediated cell-cell adhesions by mitogen-activated protein kinases
    • Wu J, Sheibani N. Modulation of VE-cadherin and PECAM-1 mediated cell-cell adhesions by mitogen-activated protein kinases. J Cell Biochem 90: 121-137, 2003.
    • (2003) J Cell Biochem , vol.90 , pp. 121-137
    • Wu, J.1    Sheibani, N.2
  • 56
    • 0028865256 scopus 로고
    • Alternative splicing of a specific cytoplasmic exon alters the binding characteristics of murine platelet/endothelial cell adhesion molecule-1 (PECAM-1)
    • Yan HC, Baldwin HS, Sun J, Buck CA, Albelda SM, DeLisser HM. Alternative splicing of a specific cytoplasmic exon alters the binding characteristics of murine platelet/endothelial cell adhesion molecule-1 (PECAM-1). J Biol Chem 270: 23672-23680, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 23672-23680
    • Yan, H.C.1    Baldwin, H.S.2    Sun, J.3    Buck, C.A.4    Albelda, S.M.5    DeLisser, H.M.6


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