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Volumn 4, Issue 2, 2010, Pages 79-85

Strategies for detecting genomic DNA methylation: A survey of US patents

Author keywords

5 methylcytosine; CpG islands; DNA methylation; Promoter methylation

Indexed keywords

5 METHYLCYTOSINE; BISULFITE; CYTOSINE; GENOMIC DNA; URACIL;

EID: 78649639254     PISSN: 18722156     EISSN: None     Source Type: Journal    
DOI: 10.2174/187221510793205719     Document Type: Article
Times cited : (4)

References (62)
  • 3
    • 4644328089 scopus 로고    scopus 로고
    • Chromosomal regulation by MeCP2: Structural and enzymatic considerations
    • Bowen NJ, Palmer MB, Wade PA. Chromosomal regulation by MeCP2: structural and enzymatic considerations. Cell Mol Life Sci 2004; 61: 2163-7.
    • (2004) Cell Mol Life Sci , vol.61 , pp. 2163-2167
    • Bowen, N.J.1    Palmer, M.B.2    Wade, P.A.3
  • 4
    • 77649267695 scopus 로고    scopus 로고
    • Dynamic changes in the human methylome during differentiation
    • Laurent L, Wong E, Li G, Huynh T, Tsirigos A, Ong CT, et al. Dynamic changes in the human methylome during differentiation. Genome Res 2010; 20: 320-331.
    • (2010) Genome Res , vol.20 , pp. 320-331
    • Laurent, L.1    Wong, E.2    Li, G.3    Huynh, T.4    Tsirigos, A.5    Ong, C.T.6
  • 5
    • 61449339872 scopus 로고    scopus 로고
    • DNA methylation: An introduction to the biology and the disease-associated changes of a promising biomarker
    • Tost J. DNA methylation: an introduction to the biology and the disease-associated changes of a promising biomarker. Methods Mol Biol 2009; 507: 3-20.
    • (2009) Methods Mol Biol , vol.507 , pp. 3-20
    • Tost, J.1
  • 6
    • 0038576158 scopus 로고    scopus 로고
    • The power and the promise of DNA methylation markers
    • Laird PW. The power and the promise of DNA methylation markers. Nat Rev Cancer 2003; 3: 253-66.
    • (2003) Nat Rev Cancer , vol.3 , pp. 253-266
    • Laird, P.W.1
  • 7
    • 0037372003 scopus 로고    scopus 로고
    • Epigenetic regulation of gene expression: How the genome integrates intrinsic and environmental signals
    • Jaenisch R, Bird A. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat Genet 2003; 33 (Suppl): 245-54.
    • (2003) Nat Genet , vol.33 , Issue.SUPPL , pp. 245-254
    • Jaenisch, R.1    Bird, A.2
  • 9
    • 0028072991 scopus 로고
    • Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma
    • Herman JG, Latif F, Weng Y, Lerman MI, Zbar B, Liu S, et al. Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma. Proc Natl Acad Sci USA 1994; 91: 9700-4.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 9700-9704
    • Herman, J.G.1    Latif, F.2    Weng, Y.3    Lerman, M.I.4    Zbar, B.5    Liu, S.6
  • 10
    • 0033557903 scopus 로고    scopus 로고
    • Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia
    • Esteller M, Hamilton SR, Burger PC, Baylin SB, Herman GJ. Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia. Cancer Res 1999; 59: 793-7.
    • (1999) Cancer Res , vol.59 , pp. 793-797
    • Esteller, M.1    Hamilton, S.R.2    Burger, P.C.3    Baylin, S.B.4    Herman, G.J.5
  • 11
    • 13144266670 scopus 로고    scopus 로고
    • Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma
    • Herman JG, Umar A, Polyak K, Baylin SB, Herman JG. Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma. Proc Natl Acad Sci USA 1998; 95: 6870-5.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 6870-6875
    • Herman, J.G.1    Umar, A.2    Polyak, K.3    Baylin, S.B.4    Herman, J.G.5
  • 12
    • 0033564351 scopus 로고    scopus 로고
    • Hypermethylation of the DAP-kinase CpG island is a common alteration in B-cell malignancies
    • Katzenellenbogen RA, Baylin SB, Herman JG. Hypermethylation of the DAP-kinase CpG island is a common alteration in B-cell malignancies. Blood 1999; 93: 4347-53.
    • (1999) Blood , vol.93 , pp. 4347-4353
    • Katzenellenbogen, R.A.1    Baylin, S.B.2    Herman, J.G.3
  • 13
    • 12144291274 scopus 로고    scopus 로고
    • Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer
    • Suzuki H, Watkins DN, Jair KW, Schuebel KE, Markowitz SD, Chen WD, et al. Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer. Nat Genet 2004; 36: 417-22.
    • (2004) Nat Genet , vol.36 , pp. 417-422
    • Suzuki, H.1    Watkins, D.N.2    Jair, K.W.3    Schuebel, K.E.4    Markowitz, S.D.5    Chen, W.D.6
  • 14
    • 0038784365 scopus 로고    scopus 로고
    • SOCS-1, a negative regulator of cytokine signaling, is frequently silenced by methylation in multiple myeloma
    • Galm O, Yoshikawa H, Esteller M, Rainhardt O, James GH. SOCS-1, a negative regulator of cytokine signaling, is frequently silenced by methylation in multiple myeloma. Blood 2003; 101: 2784-8.
    • (2003) Blood , vol.101 , pp. 2784-2788
    • Galm, O.1    Yoshikawa, H.2    Esteller, M.3    Rainhardt, O.4    James, G.H.5
  • 16
    • 0026546877 scopus 로고
    • A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands
    • Frommer M, McDonald LE, Millar DS, Collis MC, Watt F, Grigg GW, et al. A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands. Proc Natl Acad Sci USA 1992; 89: 1827-31.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 1827-1831
    • Frommer, M.1    McDonald, L.E.2    Millar, D.S.3    Collis, M.C.4    Watt, F.5    Grigg, G.W.6
  • 18
    • 47849128445 scopus 로고    scopus 로고
    • The bisulfite genomic sequencing used in the analysis of epigenetic states, a technique in the emerging environmental genotoxicology research
    • Hayatsu H. The bisulfite genomic sequencing used in the analysis of epigenetic states, a technique in the emerging environmental genotoxicology research. Mutat Res 2008; 659: 77-82.
    • (2008) Mutat Res , vol.659 , pp. 77-82
    • Hayatsu, H.1
  • 20
    • 0035041886 scopus 로고    scopus 로고
    • A novel MSP/DHPLC method for the investigation of the methylation status of imprinted genes enables the molecular detection of low cell mosaicisms
    • Baumer A, Wiedemann U, Hergersberg M, Schinzel A. A novel MSP/DHPLC method for the investigation of the methylation status of imprinted genes enables the molecular detection of low cell mosaicisms. Hum Mutat 2001; 17: 423-30.
    • (2001) Hum Mutat , vol.17 , pp. 423-430
    • Baumer, A.1    Wiedemann, U.2    Hergersberg, M.3    Schinzel, A.4
  • 21
    • 0036311281 scopus 로고    scopus 로고
    • Analysis of the methylation status of imprinted genes based on methylation-specific polymerase chain reaction combined with denaturing high-performance liquid chromatography
    • Baumer A. Analysis of the methylation status of imprinted genes based on methylation-specific polymerase chain reaction combined with denaturing high-performance liquid chromatography. Methods 2002; 27: 139-43.
    • (2002) Methods , vol.27 , pp. 139-143
    • Baumer, A.1
  • 22
    • 0037314263 scopus 로고    scopus 로고
    • DHPLC-based method for DNA methylation analysis of differential methylated regions from imprinted genes
    • Couvert P, Poirier K, Carrie A, Chalas C, Jouannet P, Beldjord C, et al. DHPLC-based method for DNA methylation analysis of differential methylated regions from imprinted genes. Biotechniques 2003; 34: 356-62.
    • (2003) Biotechniques , vol.34 , pp. 356-362
    • Couvert, P.1    Poirier, K.2    Carrie, A.3    Chalas, C.4    Jouannet, P.5    Beldjord, C.6
  • 23
    • 43849094336 scopus 로고    scopus 로고
    • A mobility shift detection method for DNA methylation analysis using phosphate affinity polyacrylamide gel electrophoresis
    • Kinoshita-Kikuta E, Kinoshita E, Koike T. A mobility shift detection method for DNA methylation analysis using phosphate affinity polyacrylamide gel electrophoresis. Anal Biochem 2008; 378: 102-4.
    • (2008) Anal Biochem , vol.378 , pp. 102-104
    • Kinoshita-Kikuta, E.1    Kinoshita, E.2    Koike, T.3
  • 24
    • 0036962761 scopus 로고    scopus 로고
    • Evaluation of a potential epigenetic biomarker by quantitative methyl-single nucleotide polymorphism analysis
    • Uhlmann K, Brinckmann A, Toliat MR, Ritter H, Nurnberg P. Evaluation of a potential epigenetic biomarker by quantitative methyl-single nucleotide polymorphism analysis. Electrophoresis 2002; 23: 4072-9.
    • (2002) Electrophoresis , vol.23 , pp. 4072-4079
    • Uhlmann, K.1    Brinckmann, A.2    Toliat, M.R.3    Ritter, H.4    Nurnberg, P.5
  • 25
    • 41149156894 scopus 로고    scopus 로고
    • A nanocarbon film electrode as a platform for exploring DNA methylation
    • Kato D, Sekioka N, Ueda A, Kurita R, Hirono S, Suzuki K. A nanocarbon film electrode as a platform for exploring DNA methylation. J Am Chem Soc 2008; 130: 3716-7.
    • (2008) J Am Chem Soc , vol.130 , pp. 3716-3717
    • Kato, D.1    Sekioka, N.2    Ueda, A.3    Kurita, R.4    Hirono, S.5    Suzuki, K.6
  • 26
    • 36348956688 scopus 로고    scopus 로고
    • A new dimethyl sulfoxide-based method for gene promoter methylation detection
    • Kholod N, Boniver J, Delvenne P. A new dimethyl sulfoxide-based method for gene promoter methylation detection. J Mol Diagn 2007; 9: 574-81.
    • (2007) J Mol Diagn , vol.9 , pp. 574-581
    • Kholod, N.1    Boniver, J.2    Delvenne, P.3
  • 27
    • 61549137178 scopus 로고    scopus 로고
    • Emerging methods for analysis of the cancer methylome
    • Chang JW, Huang TH, Wang YC. Emerging methods for analysis of the cancer methylome. Pharmacogenomics 2008; 9: 1869-78.
    • (2008) Pharmacogenomics , vol.9 , pp. 1869-1878
    • Chang, J.W.1    Huang, T.H.2    Wang, Y.C.3
  • 28
    • 0030825309 scopus 로고    scopus 로고
    • COBRA: A sensitive and quantitative DNA methylation assay
    • Xiong Z, Laird PW. COBRA: a sensitive and quantitative DNA methylation assay. Nucleic Acids Res 1997; 25: 2532-4.
    • (1997) Nucleic Acids Res , vol.25 , pp. 2532-2534
    • Xiong, Z.1    Laird, P.W.2
  • 29
    • 34548188589 scopus 로고    scopus 로고
    • Methylation-sensitive single-nucleotide primer extension (Ms-SNuPE) for quantitative measurement of DNA methylation
    • Gonzalgo ML, Liang G. Methylation-sensitive single-nucleotide primer extension (Ms-SNuPE) for quantitative measurement of DNA methylation. Nat Protoc 2007; 2: 1931-6.
    • (2007) Nat Protoc , vol.2 , pp. 1931-1936
    • Gonzalgo, M.L.1    Liang, G.2
  • 32
    • 5444256342 scopus 로고    scopus 로고
    • Methylation-sensitive single-strand conformation analysis: A rapid method to screen for and analyze DNA methylation
    • Benhattar J, Clement G. Methylation-sensitive single-strand conformation analysis: a rapid method to screen for and analyze DNA methylation. Methods Mol Biol 2004; 287: 181-93.
    • (2004) Methods Mol Biol , vol.287 , pp. 181-193
    • Benhattar, J.1    Clement, G.2
  • 33
    • 24044464247 scopus 로고    scopus 로고
    • Methylation-specific MLPA (MS-MLPA): Simultaneous detection of CpG methylation and copy number changes of up to 40 sequences
    • Nygren AO, Ameziane N, Duarte HM, Vijzelaar RN, Waisfisz Q, Hess CJ, et al. Methylation-specific MLPA (MS-MLPA): simultaneous detection of CpG methylation and copy number changes of up to 40 sequences. Nucleic Acids Res 2005; 33: e128.
    • (2005) Nucleic Acids Res , vol.e128 , pp. 33
    • Nygren, A.O.1    Ameziane, N.2    Duarte, H.M.3    Vijzelaar, R.N.4    Waisfisz, Q.5    Hess, C.J.6
  • 34
    • 34247136384 scopus 로고    scopus 로고
    • Techniques used in studies of epigenome dysregulation due to aberrant DNA methylation: An emphasis on fetal-based adult diseases
    • Ho SM, Tang WY. Techniques used in studies of epigenome dysregulation due to aberrant DNA methylation: an emphasis on fetal-based adult diseases. Reprod Toxicol 2007; 23: 267-82.
    • (2007) Reprod Toxicol , vol.23 , pp. 267-282
    • Ho, S.M.1    Tang, W.Y.2
  • 35
    • 33745315497 scopus 로고    scopus 로고
    • Promoter array studies identify cohorts of genes directly regulated by methylation, copy number change, or transcription factor binding in human cancer cells
    • Wang Y, Hayakawa J, Long F, Quiju Y, Cho AH, Rondeau G, et al. Promoter array studies identify cohorts of genes directly regulated by methylation, copy number change, or transcription factor binding in human cancer cells. Ann N Y Acad Sci 2005; 1058: 162-85.
    • (2005) Ann N Y Acad Sci , vol.1058 , pp. 162-185
    • Wang, Y.1    Hayakawa, J.2    Long, F.3    Quiju, Y.4    Cho, A.H.5    Rondeau, G.6
  • 36
    • 55849128917 scopus 로고    scopus 로고
    • Recent patents concerning diagnostic and therapeutic applications of aberrantly methylated sequences in pancreatic cancer
    • Wehrum D, Grutzmann R, Hennig M, Saeger HD, Pilarsky C. Recent patents concerning diagnostic and therapeutic applications of aberrantly methylated sequences in pancreatic cancer. Recent Pat DNA Gene Seq 2008; 2: 97-106.
    • (2008) Recent Pat DNA Gene Seq , vol.2 , pp. 97-106
    • Wehrum, D.1    Grutzmann, R.2    Hennig, M.3    Saeger, H.D.4    Pilarsky, C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.