Alcohol alters hepatic FoxO1, p53, and mitochondrial SIRT5 deacetylation function

Biochemical and Biophysical Research Communications

Volumn 373, Issue 2, 2008, Pages 246-252

  Lieber, Charles S ^a,b   Leo, Maria Anna ^a,b   Wang, Xiaolei ^b   DeCarli, Leonore M ^a  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Alcohol; Foxo1; Liver; Mitochondria; p53; SIRT5

Indexed keywords

ALCOHOL; MESSENGER RNA; NICOTINAMIDE ADENINE DINUCLEOTIDE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PROTEIN P53; SIRTUIN 1; SIRTUIN 5; TRANSCRIPTION FACTOR FKHR; TRANSFERASE;

ACETYLATION; ALCOHOL CONSUMPTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; MALE; MITOCHONDRION; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN SYNTHESIS; RAT; REACTION ANALYSIS; SPRAGUE DAWLEY RAT;

ACETYLATION; ALCOHOL DRINKING; ANIMALS; ETHANOL; FORKHEAD TRANSCRIPTION FACTORS; MALE; MITOCHONDRIA; NERVE TISSUE PROTEINS; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; SIRTUINS; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEIN P53;

RATTUS;

EID: 46049084164     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.06.006     Document Type: Article

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