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Volumn 95, Issue 12, 2010, Pages 1132-1144

Altered ion transport by thyroid epithelia from CFTR-/- pigs suggests mechanisms for hypothyroidism in cystic fibrosis

Author keywords

[No Author keywords available]

Indexed keywords

AMILORIDE; CHLORIDE ION; EPITHELIAL SODIUM CHANNEL; ISOPRENALINE; PENDRIN; SODIUM ION; TRANSMEMBRANE CONDUCTANCE REGULATOR;

EID: 78649615188     PISSN: 09580670     EISSN: 1469445X     Source Type: Journal    
DOI: 10.1113/expphysiol.2010.054700     Document Type: Article
Times cited : (41)

References (69)
  • 3
    • 0026731615 scopus 로고
    • Chloride conductance of apical membrane in cultured porcine thyroid cells activated by cyclic AMP
    • Armstrong JW, Cragoe EJ Jr, Bourke JR, Huxham GJ & Manley SW (1992b). Chloride conductance of apical membrane in cultured porcine thyroid cells activated by cyclic AMP. Mol Cell Endocrinol 88, 105-110.
    • (1992) Mol Cell Endocrinol , vol.88 , pp. 105-110
    • Armstrong, J.W.1    Cragoe Jr, E.J.2    Bourke, J.R.3    Huxham, G.J.4    Manley, S.W.5
  • 4
    • 34047166052 scopus 로고    scopus 로고
    • Airway surface dehydration in cystic fibrosis: pathogenesis and therapy
    • Boucher RC (2007a). Airway surface dehydration in cystic fibrosis: pathogenesis and therapy. Annu Rev Med 58, 157-170.
    • (2007) Annu Rev Med , vol.58 , pp. 157-170
    • Boucher, R.C.1
  • 5
    • 34249662628 scopus 로고    scopus 로고
    • Cystic fibrosis: a disease of vulnerability to airway surface dehydration
    • Boucher RC (2007b). Cystic fibrosis: a disease of vulnerability to airway surface dehydration. Trends Mol Med 13, 231-240.
    • (2007) Trends Mol Med , vol.13 , pp. 231-240
    • Boucher, R.C.1
  • 6
    • 33845992179 scopus 로고    scopus 로고
    • Evidence for airway surface dehydration as the initiating event in CF airway disease
    • Boucher RC (2007c). Evidence for airway surface dehydration as the initiating event in CF airway disease. J Intern Med 261, 5-16.
    • (2007) J Intern Med , vol.261 , pp. 5-16
    • Boucher, R.C.1
  • 8
    • 0029959063 scopus 로고    scopus 로고
    • Sodium channel heterogeneity in the apical membrane of porcine thyroid epithelial cells
    • Bourke JR, Abel KC, Huxham GJ, Sand O & Manley SW (1996). Sodium channel heterogeneity in the apical membrane of porcine thyroid epithelial cells. J Endocrinol 149, 101-108.
    • (1996) J Endocrinol , vol.149 , pp. 101-108
    • Bourke, J.R.1    Abel, K.C.2    Huxham, G.J.3    Sand, O.4    Manley, S.W.5
  • 9
    • 0023619197 scopus 로고
    • Cyclic AMP-stimulated fluid transport in the thyroid: influence of thyroid stimulators, amiloride and acetazolamide on the dynamics of domes in monolayer cultures of porcine thyroid cells
    • Bourke JR, Matainaho T, Huxham GJ & Manley SW (1987). Cyclic AMP-stimulated fluid transport in the thyroid: influence of thyroid stimulators, amiloride and acetazolamide on the dynamics of domes in monolayer cultures of porcine thyroid cells. J Endocrinol 115, 19-26.
    • (1987) J Endocrinol , vol.115 , pp. 19-26
    • Bourke, J.R.1    Matainaho, T.2    Huxham, G.J.3    Manley, S.W.4
  • 10
    • 0028790621 scopus 로고
    • Chloride channels in the apical membrane of thyroid epithelial cells are regulated by cyclic AMP
    • Bourke JR, Sand O, Abel KC, Huxham GJ & Manley SW (1995). Chloride channels in the apical membrane of thyroid epithelial cells are regulated by cyclic AMP. J Endocrinol 147, 441-448.
    • (1995) J Endocrinol , vol.147 , pp. 441-448
    • Bourke, J.R.1    Sand, O.2    Abel, K.C.3    Huxham, G.J.4    Manley, S.W.5
  • 14
    • 0027288003 scopus 로고
    • Iodide transport in the thyroid gland
    • Carrasco N (1993). Iodide transport in the thyroid gland. Biochim Biophys Acta 1154, 65-82.
    • (1993) Biochim Biophys Acta , vol.1154 , pp. 65-82
    • Carrasco, N.1
  • 15
    • 0025014729 scopus 로고
    • Small conductance chloride channels in the apical membrane of thyroid cells
    • Champigny G, Verrier B, Gerard C, Mauchamp J & Lazdunski M (1990). Small conductance chloride channels in the apical membrane of thyroid cells. FEBS Lett 259, 263-268.
    • (1990) FEBS Lett , vol.259 , pp. 263-268
    • Champigny, G.1    Verrier, B.2    Gerard, C.3    Mauchamp, J.4    Lazdunski, M.5
  • 16
    • 39049152539 scopus 로고    scopus 로고
    • Relative quantification of mRNA: comparison of methods currently used for real-time PCR data analysis
    • Cikos S, Bukovská A & Koppel J (2007). Relative quantification of mRNA: comparison of methods currently used for real-time PCR data analysis. BMC Mol Biol 8, 113.
    • (2007) BMC Mol Biol , vol.8 , pp. 113
    • Cikos, S.1    Bukovská, A.2    Koppel, J.3
  • 18
    • 0030053759 scopus 로고    scopus 로고
    • Cloning and characterization of the thyroid iodide transporter
    • Dai G, Levy O & Carrasco N (1996). Cloning and characterization of the thyroid iodide transporter. Nature 379, 458-460.
    • (1996) Nature , vol.379 , pp. 458-460
    • Dai, G.1    Levy, O.2    Carrasco, N.3
  • 19
    • 0033922682 scopus 로고    scopus 로고
    • Molecular analysis of the sodium/iodide symporter: impact on thyroid and extrathyroid pathophysiology
    • De La Vieja A, Dohan O, Levy O & Carrasco N (2000). Molecular analysis of the sodium/iodide symporter: impact on thyroid and extrathyroid pathophysiology. Physiol Rev 80, 1083-1105.
    • (2000) Physiol Rev , vol.80 , pp. 1083-1105
    • De La Vieja, A.1    Dohan, O.2    Levy, O.3    Carrasco, N.4
  • 21
    • 77952486738 scopus 로고    scopus 로고
    • Molecular and functional characterization of the cystic fibrosis transmembrane conductance regulator from the Australian common brushtail possum, Trichosurus vulpecula
    • Demmers KJ, Carter D, Fan S, Mao P, Maqbool NJ, McLeod BJ et al . (2010). Molecular and functional characterization of the cystic fibrosis transmembrane conductance regulator from the Australian common brushtail possum, Trichosurus vulpecula. J Comp Physiol B 180, 545-561.
    • (2010) J Comp Physiol B , vol.180 , pp. 545-561
    • Demmers, K.J.1    Carter, D.2    Fan, S.3    Mao, P.4    Maqbool, N.J.5    McLeod, B.J.6
  • 23
    • 36348979793 scopus 로고    scopus 로고
    • Sodium channels and cystic fibrosis
    • Donaldson SH & Boucher RC (2007). Sodium channels and cystic fibrosis. Chest 132, 1631-1636.
    • (2007) Chest , vol.132 , pp. 1631-1636
    • Donaldson, S.H.1    Boucher, R.C.2
  • 25
    • 0033578352 scopus 로고    scopus 로고
    • Expression pattern of the mouse ortholog of the Pendred's syndrome gene (Pds) suggests a key role for pendrin in the inner ear
    • Everett LA, Morsli H, Wu DK & Green ED (1999). Expression pattern of the mouse ortholog of the Pendred's syndrome gene (Pds) suggests a key role for pendrin in the inner ear. Proc Natl Acad Sci USA 96, 9727-9732.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 9727-9732
    • Everett, L.A.1    Morsli, H.2    Wu, D.K.3    Green, E.D.4
  • 26
    • 2342656361 scopus 로고    scopus 로고
    • Bicarbonate secretion: it takes two to tango
    • Gray MA (2004). Bicarbonate secretion: it takes two to tango. Nat Cell Biol 6, 292-294.
    • (2004) Nat Cell Biol , vol.6 , pp. 292-294
    • Gray, M.A.1
  • 28
    • 0032962320 scopus 로고    scopus 로고
    • Pathophysiology of gene-targeted mouse models for cystic fibrosis
    • Grubb BR & Boucher RC (1999). Pathophysiology of gene-targeted mouse models for cystic fibrosis. Physiol Rev 79, S193-S214.
    • (1999) Physiol Rev , vol.79
    • Grubb, B.R.1    Boucher, R.C.2
  • 29
    • 0037404439 scopus 로고    scopus 로고
    • Translational physiology: porcine models of human coronary artery disease: implications for preclinical trials of therapeutic angiogenesis
    • Hughes GC, Post MJ, Simons M & Annex BH (2003). Translational physiology: porcine models of human coronary artery disease: implications for preclinical trials of therapeutic angiogenesis. J Appl Physiol 94, 1689-1701.
    • (2003) J Appl Physiol , vol.94 , pp. 1689-1701
    • Hughes, G.C.1    Post, M.J.2    Simons, M.3    Annex, B.H.4
  • 30
    • 35148895083 scopus 로고    scopus 로고
    • Thyroid disease and the heart
    • Klein I & Danzi S (2007). Thyroid disease and the heart. Circulation 116, 1725-1735.
    • (2007) Circulation , vol.116 , pp. 1725-1735
    • Klein, I.1    Danzi, S.2
  • 31
    • 68949094195 scopus 로고    scopus 로고
    • ENaC at the cutting edge: regulation of epithelial sodium channels by proteases
    • Kleyman TR, Carattino MD & Hughey RP (2009). ENaC at the cutting edge: regulation of epithelial sodium channels by proteases. J Biol Chem 284, 20447-20451.
    • (2009) J Biol Chem , vol.284 , pp. 20447-20451
    • Kleyman, T.R.1    Carattino, M.D.2    Hughey, R.P.3
  • 33
    • 77952942959 scopus 로고    scopus 로고
    • Cystic fibrosis transmembrane conductance regulator trafficking modulates the barrier function of airway epithelial cell monolayers
    • LeSimple P, Liao J, Robert R, Gruenert DC & Hanrahan JW (2010). Cystic fibrosis transmembrane conductance regulator trafficking modulates the barrier function of airway epithelial cell monolayers. J Physiol 588, 1195-1209.
    • (2010) J Physiol , vol.588 , pp. 1195-1209
    • LeSimple, P.1    Liao, J.2    Robert, R.3    Gruenert, D.C.4    Hanrahan, J.W.5
  • 35
    • 45849126788 scopus 로고    scopus 로고
    • Mild processing defect of porcine δF508-CFTR suggests that δF508 pigs may not develop cystic fibrosis disease
    • Liu Y, Wang Y, Jiang Y, Zhu N, Liang H, Xu L et al . (2008). Mild processing defect of porcine δF508-CFTR suggests that δF508 pigs may not develop cystic fibrosis disease. Biochem Biophys Res Commun 373, 113-118.
    • (2008) Biochem Biophys Res Commun , vol.373 , pp. 113-118
    • Liu, Y.1    Wang, Y.2    Jiang, Y.3    Zhu, N.4    Liang, H.5    Xu, L.6
  • 36
    • 77949329263 scopus 로고    scopus 로고
    • Thyroid hormone crosstalk with nuclear receptor signaling in metabolic regulation
    • Liu YY & Brent GA (2010). Thyroid hormone crosstalk with nuclear receptor signaling in metabolic regulation. Trends Endocrinol Metab 21, 166-173.
    • (2010) Trends Endocrinol Metab , vol.21 , pp. 166-173
    • Liu, Y.Y.1    Brent, G.A.2
  • 37
    • 0014318713 scopus 로고
    • Elevated sweat chlorides and hypothyroidism
    • Madoff L (1968). Elevated sweat chlorides and hypothyroidism. J Pediatr 73, 244-246.
    • (1968) J Pediatr , vol.73 , pp. 244-246
    • Madoff, L.1
  • 39
    • 0032698749 scopus 로고    scopus 로고
    • Aldosterone-mediated regulation of ENaC α, β, and γ subunit proteins in rat kidney
    • Masilamani S, Kim GH, Mitchell C, Wade JB & Knepper MA (1999). Aldosterone-mediated regulation of ENaC α, β, and γ subunit proteins in rat kidney. J Clin Invest 104, R19-R23.
    • (1999) J Clin Invest , vol.104
    • Masilamani, S.1    Kim, G.H.2    Mitchell, C.3    Wade, J.B.4    Knepper, M.A.5
  • 40
    • 0025126939 scopus 로고
    • Iodide transport in primary cultured thyroid follicle cells: evidence of a TSH-regulated channel mediating iodide efflux selectively across the apical domain of the plasma membrane
    • Nilsson M, Bjorkman U, Ekholm R & Ericson LE (1990). Iodide transport in primary cultured thyroid follicle cells: evidence of a TSH-regulated channel mediating iodide efflux selectively across the apical domain of the plasma membrane. Eur J Cell Biol 52, 270-281.
    • (1990) Eur J Cell Biol , vol.52 , pp. 270-281
    • Nilsson, M.1    Bjorkman, U.2    Ekholm, R.3    Ericson, L.E.4
  • 41
    • 0026604615 scopus 로고
    • Polarized efflux of iodide in porcine thyrocytes occurs via a cAMP-regulated iodide channel in the apical plasma membrane
    • Nilsson M, Björkman U, Ekholm R & Ericson LE (1992). Polarized efflux of iodide in porcine thyrocytes occurs via a cAMP-regulated iodide channel in the apical plasma membrane. Acta Endocrinol (Copenh) 126, 67-74.
    • (1992) Acta Endocrinol (Copenh) , vol.126 , pp. 67-74
    • Nilsson, M.1    Björkman, U.2    Ekholm, R.3    Ericson, L.E.4
  • 43
    • 0033382812 scopus 로고    scopus 로고
    • Could growth retardation in cystic fibrosis be partly due to deficient steroid and thyroid hormonogenesis?
    • Panesar NS (1999). Could growth retardation in cystic fibrosis be partly due to deficient steroid and thyroid hormonogenesis? Med Hypotheses 53, 530-532.
    • (1999) Med Hypotheses , vol.53 , pp. 530-532
    • Panesar, N.S.1
  • 44
  • 45
    • 0242317675 scopus 로고    scopus 로고
    • Experimental validation of novel and conventional approaches to quantitative real-time PCR data analysis
    • Peirson SN, Butler JN & Foster RG (2003). Experimental validation of novel and conventional approaches to quantitative real-time PCR data analysis. Nucleic Acids Res 31, e73.
    • (2003) Nucleic Acids Res , vol.31
    • Peirson, S.N.1    Butler, J.N.2    Foster, R.G.3
  • 46
    • 0024317655 scopus 로고
    • The thyroid cell monolayer in culture. A tight sodium absorbing epithelium
    • Penel C, Gerard C, Mauchamp J & Verrier B (1989). The thyroid cell monolayer in culture. A tight sodium absorbing epithelium. Pflugers Arch 414, 509-515.
    • (1989) Pflugers Arch , vol.414 , pp. 509-515
    • Penel, C.1    Gerard, C.2    Mauchamp, J.3    Verrier, B.4
  • 47
    • 0029816943 scopus 로고    scopus 로고
    • Function of Xenopus cystic fibrosis transmembrane conductance regulator (CFTR) Cl channels and use of human-Xenopus chimeras to investigate the pore properties of CFTR
    • Price MP, Ishihara H, Sheppard DN & Welsh MJ (1996). Function of Xenopus cystic fibrosis transmembrane conductance regulator (CFTR) Cl channels and use of human-Xenopus chimeras to investigate the pore properties of CFTR. J Biol Chem 271, 25184-25191.
    • (1996) J Biol Chem , vol.271 , pp. 25184-25191
    • Price, M.P.1    Ishihara, H.2    Sheppard, D.N.3    Welsh, M.J.4
  • 48
    • 0034484796 scopus 로고    scopus 로고
    • Hormones increase mRNA of cyclic-nucleotide-gated cation channels in airway epithelia
    • Qiu W, Laheri A, Leung S & Guggino SE (2000). Hormones increase mRNA of cyclic-nucleotide-gated cation channels in airway epithelia. Pflugers Arch 441, 69-77.
    • (2000) Pflugers Arch , vol.441 , pp. 69-77
    • Qiu, W.1    Laheri, A.2    Leung, S.3    Guggino, S.E.4
  • 50
    • 0024424270 scopus 로고
    • Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA
    • Riordan JR, Rommens JM, Kerem B, Alon N, Rozmahel R, Grzelczak Z et al . (1989). Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA. Science 245, 1066-1073.
    • (1989) Science , vol.245 , pp. 1066-1073
    • Riordan, J.R.1    Rommens, J.M.2    Kerem, B.3    Alon, N.4    Rozmahel, R.5    Grzelczak, Z.6
  • 52
    • 41849148289 scopus 로고    scopus 로고
    • Production of CFTR-null and CFTR-δF508 heterozygous pigs by adeno-associated virus-mediated gene targeting and somatic cell nuclear transfer
    • Rogers CS, Hao Y, Rokhlina T, Samuel M, Stoltz DA, Li Y et al . (2008a). Production of CFTR-null and CFTR-δF508 heterozygous pigs by adeno-associated virus-mediated gene targeting and somatic cell nuclear transfer. J Clin Invest 118, 1571-1577.
    • (2008) J Clin Invest , vol.118 , pp. 1571-1577
    • Rogers, C.S.1    Hao, Y.2    Rokhlina, T.3    Samuel, M.4    Stoltz, D.A.5    Li, Y.6
  • 53
    • 52949154301 scopus 로고    scopus 로고
    • Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs
    • Rogers CS, Stoltz DA, Meyerholz DK, Ostedgaard LS, Rokhlina T et al . (2008b). Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs. Science 321, 1837-1841.
    • (2008) Science , vol.321 , pp. 1837-1841
    • Rogers, C.S.1    Stoltz, D.A.2    Meyerholz, D.K.3    Ostedgaard, L.S.4    Rokhlina, T.5
  • 54
    • 0034463973 scopus 로고    scopus 로고
    • Pendrin, the protein encoded by the Pendred syndrome gene (PDS), is an apical porter of iodide in the thyroid and is regulated by thyroglobulin in FRTL-5 cells
    • Royaux IE, Suzuki K, Mori A, Katoh R, Everett LA, Kohn LD et al . (2000). Pendrin, the protein encoded by the Pendred syndrome gene (PDS), is an apical porter of iodide in the thyroid and is regulated by thyroglobulin in FRTL-5 cells. Endocrinology 141, 839-845.
    • (2000) Endocrinology , vol.141 , pp. 839-845
    • Royaux, I.E.1    Suzuki, K.2    Mori, A.3    Katoh, R.4    Everett, L.A.5    Kohn, L.D.6
  • 59
    • 0032912589 scopus 로고    scopus 로고
    • Structure and function of the CFTR chloride channel
    • Sheppard DN & Welsh MJ (1999). Structure and function of the CFTR chloride channel. Physiol Rev 79, S23-S45.
    • (1999) Physiol Rev , vol.79
    • Sheppard, D.N.1    Welsh, M.J.2
  • 61
    • 0026629383 scopus 로고
    • The cystic fibrosis transmembrane conductance regulator chloride channel. Iodide block and permeation
    • Tabcharani JA, Chang XB, Riordan JR & Hanrahan JW (1992). The cystic fibrosis transmembrane conductance regulator chloride channel. Iodide block and permeation. Biophys J 62, 1-4.
    • (1992) Biophys J , vol.62 , pp. 1-4
    • Tabcharani, J.A.1    Chang, X.B.2    Riordan, J.R.3    Hanrahan, J.W.4
  • 62
    • 0030964656 scopus 로고    scopus 로고
    • Halide permeation in wild-type and mutant cystic fibrosis transmembrane conductance regulator chloride channels
    • Tabcharani JA, Linsdell P & Hanrahan JW (1997). Halide permeation in wild-type and mutant cystic fibrosis transmembrane conductance regulator chloride channels. J Gen Physiol 110, 341-354.
    • (1997) J Gen Physiol , vol.110 , pp. 341-354
    • Tabcharani, J.A.1    Linsdell, P.2    Hanrahan, J.W.3
  • 63
    • 33646763506 scopus 로고    scopus 로고
    • Amiodarone inhibits thyroidal iodide transport in vitro by a cyclic adenosine 5'-monophosphate- and iodine-independent mechanism
    • Tedelind S, Larsson F, Johanson C, Van Beeren HC, Wiersinga WM, Nyström E et al . (2006). Amiodarone inhibits thyroidal iodide transport in vitro by a cyclic adenosine 5'-monophosphate- and iodine-independent mechanism. Endocrinology 147, 2936-2943.
    • (2006) Endocrinology , vol.147 , pp. 2936-2943
    • Tedelind, S.1    Larsson, F.2    Johanson, C.3    Van Beeren, H.C.4    Wiersinga, W.M.5    Nyström6    et, al.E.7
  • 64
    • 32644449168 scopus 로고    scopus 로고
    • The loss of the chloride channel, ClC-5, delays apical iodide efflux and induces a euthyroid goiter in the mouse thyroid gland
    • Van Den Hove MF, Croizet-Berger K, Jouret F, Guggino SE, Guggino WB, Devuyst O et al . (2006). The loss of the chloride channel, ClC-5, delays apical iodide efflux and induces a euthyroid goiter in the mouse thyroid gland. Endocrinology 147, 1287-1296.
    • (2006) Endocrinology , vol.147 , pp. 1287-1296
    • Van Den Hove, M.F.1    Croizet-Berger, K.2    Jouret, F.3    Guggino, S.E.4    Guggino, W.B.5    Devuyst, O.6
  • 66
    • 70350705957 scopus 로고    scopus 로고
    • Developmental delays consistent with cochlear hypothyroidism contribute to failure to develop hearing in mice lacking Slc26a4/pendrin expression
    • Wangemann P, Kim HM, Billings S, Nakaya K, Li X, Singh R et al . (2009). Developmental delays consistent with cochlear hypothyroidism contribute to failure to develop hearing in mice lacking Slc26a4/pendrin expression. Am J Physiol Renal Physiol 297, F1435-F1447.
    • (2009) Am J Physiol Renal Physiol , vol.297
    • Wangemann, P.1    Kim, H.M.2    Billings, S.3    Nakaya, K.4    Li, X.5    Singh, R.6
  • 67
    • 0001752544 scopus 로고    scopus 로고
    • Metabolic and Molecular Basis of Inherited Disease
    • ed. Scriver CR, Beaudet AL, Sly WS &, Valle D -. McGraw-Hill, New York
    • Welsh MJ, Ramsey BW, Accurso F & Cutting G (2001). Cystic fibrosis. In Metabolic and Molecular Basis of Inherited Disease, ed. Scriver CR, Beaudet AL, Sly WS & Valle D, pp. 5121-5188. McGraw-Hill, New York .
    • (2001) Cystic fibrosis , pp. 5121-5188
    • Welsh, M.J.1    Ramsey, B.W.2    Accurso, F.3    Cutting, G.4


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