Impact of predatory threat on fear extinction in Lewis rats

Learning and Memory

Volumn 17, Issue 10, 2010, Pages 494-501

  Goswami, Sonal ^a   Cascardi, Michele ^a,b   Rodríguez Sierra, Olga E ^a   Duvarci, Sevil ^a   Paré, Denis ^a  

^a RUTGERS UNIVERSITY   (United States)

^b MONTCLAIR STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONDITIONING; CONTROLLED STUDY; EXPLORATORY BEHAVIOR; FEAR; HABITUATION; LEWIS RAT; MALE; MAZE TEST; MEMORY; MENTAL STRESS; NONHUMAN; PATHOPHYSIOLOGY; POSTTRAUMATIC STRESS DISORDER; PREDATION; PRIORITY JOURNAL; RAT; RECALL; REINFORCEMENT; THREAT;

ACOUSTIC STIMULATION; ANIMALS; CONDITIONING, CLASSICAL; DISEASE MODELS, ANIMAL; EXPLORATORY BEHAVIOR; EXTINCTION, PSYCHOLOGICAL; FEAR; FREEZING REACTION, CATALEPTIC; MAZE LEARNING; PREDATORY BEHAVIOR; RATS; RATS, INBRED LEW; STRESS DISORDERS, POST-TRAUMATIC; TIME FACTORS;

EID: 78649540996     PISSN: 10720502     EISSN: 15495485     Source Type: Journal    
DOI: 10.1101/lm.1948910     Document Type: Article

References (48)

1. Adamec RE, Shallow T. 1993. Lasting effects on rodent anxiety of a single exposure to a cat. Physiol Behav 54: 101-109. (Pubitemid 23172429)
2. Adamec R, Head D, Blundell J, Burton P, Berton O. 2006. Lasting anxiogenic effects of feline predator stress in mice: Sex differences in vulnerability to stress and predicting severity of anxiogenic response from the stress experience. Physiol Behav 88: 12-29. (Pubitemid 43795970)
3. Afifi TO, Asmundson GJ, Taylor S, Jang KL. 2010. The role of genes and environment on trauma exposure and posttraumatic stress disorder symptoms: A review of twin studies. Clin Psychol Rev 30: 101-112.
4. Apfelbach R, Blanchard CD, Blanchard RJ, Hayes RA, McGregor IS. 2005. The effects of predator odors in mammalian prey species: A review of field and laboratory studies. Neurosci Biobehav Rev 29: 1123-1144. (Pubitemid 41446891)
5. Armario A, Escorihuela RM, Nadal R. 2008. Long-term neuroendocrine and behavioural effects of a single exposure to stress in adult animals. Neurosci Biobehav Rev 32: 1121-1135.
6. Baran SE, Armstrong CE, Niren DC, Hanna JJ, Conrad CD. 2009. Chronic stress and sex differences on the recall of fear conditioning and extinction. Neurobiol Learn Mem 91: 323-332.
7. Binder EB, Bradley RG, Liu W, Epstein MP, Deveau TC, Mercer KB, Tang Y, Gillespie CF, Heim CM, Nemeroff CB, et al. 2008. Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults. JAMA 299: 1291-1305. (Pubitemid 351439075)
8. Blanchard RJ, Yang M, Li CI, Gervacio A, Blanchard DC. 2001. Cue and context conditioning of defensive behaviors to cat odor stimuli. Neurosci Biobehav Rev 25: 587-595. (Pubitemid 34136888)
9. Blanchard DC, Griebel G, Blanchard RJ. 2003. Conditioning and residual emotionality effects of predator stimuli: Some reflections on stress and emotion. Prog Neuropsychopharmacol Biol Psychiatry 27: 1177-1185. (Pubitemid 37501024)
10. Blechert J, Michael T, Vriends N, Margraf J, Wilhelm FH. 2007. Fear conditioning in posttraumatic stress disorder: Evidence for delayed extinction of autonomic, experiential, and behavioural responses. Behav Res Ther 45: 2019-2033. (Pubitemid 47210952)
11. Bremner JD, Elzinga B, Schmahl C, Vermetten E. 2008. Structural and functional plasticity of the human brain in posttraumatic stress disorder. Prog Brain Res 167: 171-186.
12. Burgos-Robles A, Vidal-Gonzalez I, Santini E, Quirk GJ. 2007. Consolidation of fear extinction requires NMDA receptor-dependent bursting in the ventromedial prefrontal cortex. Neuron 53: 871-880. (Pubitemid 46367556)
13. Camp M, Norcross M, Whittle N, Feyder M, D'Hanis W, Yilmazer-Hanke D, Singewald N, Holmes A. 2009. Impaired Pavlovian fear extinction is a common phenotype across genetic lineages of the 129 inbred mouse strain. Genes Brain Behav 8: 744-752.
14. Chantarujikapong SI, Scherrer JF, Xian H, Eisen SA, Lyons MJ, Goldberg J, Tsuang M, True WR. 2001. A twin study of generalized anxiety disorder symptoms, panic disorder symptoms and post-traumatic stress disorder in men. Psychiatry Res 103: 133-145.
15. Cohen H, Matar MA, Richter-Levin G, Zohar J. 2006a. The contribution of an animal model toward uncovering biological risk factors for PTSD. Ann NY Acad Sci 1071: 335-350.
16. Cohen H, Zohar J, Gidron Y, Matar MA, Belkind D, Loewenthal U, Kozlovsky N, Kaplan Z. 2006b. Blunted HPA axis response to stress influences susceptibility to posttraumatic stress response in rats. Biol Psychiatry 59: 1208-1218. (Pubitemid 43912551)
17. Duvarci S, Bauer EP, Pare D. 2009. The bed nucleus of the stria terminalis mediates inter-individual differences in anxiety and fear. J Neurosci 29: 10357-10361.
18. Fu Q, Koenen KC, Miller MW, Heath AC, Bucholz KK, Lyons MJ, Eisen SA, True WR, Goldberg J, Tsuang MT. 2007. Differential etiology of posttraumatic stress disorder with conduct disorder and major depression in male veterans. Biol Psychiatry 62: 1088-1094.
19. Gilbertson MW, Shenton ME, Ciszewski A, Kasai K, Lasko NB, Orr SP, Pitman RK. 2002. Smaller hippocampal volume predicts pathologic vulnerability to psychological trauma. Nat Neurosci 5: 1242-1247. (Pubitemid 35247185)
20. Gilbertson MW, Williston SK, Paulus LA, Lasko NB, Gurvits TV, Shenton ME, Pitman RK, Orr SP. 2007. Configural cue performance in identical twins discordant for posttraumatic stress disorder: Theoretical implications for the role of hippocampal function. Biol Psychiatry 62:513-520.
21. Guthrie RM, Bryant RA. 2006. Extinction learning before trauma and subsequent posttraumatic stress. Psychosom Med 68: 307-311.
22. Jovanovic T, Ressler KJ. 2010. How the neurocircuitry and genetics of fear inhibition may informour understanding of PTSD. Am J Psychiatry 167: 648-62.
23. Keane TM, Zimering RT, Caddell JM. 1985. A behavioral formulation of post-traumatic stress disorder in Vietnam veterans. Behav Ther 8: 9-12.
24. Kilpatrick DG, Koenen KC, Ruggiero KJ, Acierno R, Galea S, Resnick HS, Roitzsch J, Boyle J, Gelernter J. 2007. The serotonin transporter genotype and social support and moderation of posttraumatic stress disorder and depression in hurricane-exposed adults. Am J Psychiatry 164: 1693-1699.
25. Kitayama N, Vaccarino V, Kutner M, Weiss P, Bremner JD. 2005. Magnetic resonance imaging (MRI) measurement of hippocampal volume in posttraumatic stress disorder: A meta-analysis. J Affect Disord 88: 79-86.
26. McGregor IS, Schrama L, Ambermoon P, Dielenberg RA. 2002. Not all 'predator odours' are equal: Cat odour but not 2,4,5 trimethylthiazoline (TMT; fox odour) elicits specific defensive behaviours in rats. Behav Brain Res 129: 1-16.
27. McNally RJ. 2002. On nonassociative fear emergence. Behav Res Ther 40: 169-172.
28. Milad MR, Quirk GJ. 2002. Neurons in medial prefrontal cortex signal memory for fear extinction. Nature 420: 70-74.
29. Milad MR, Orr SP, Lasko NB, Chang Y, Rauch SL, Pitman RK. 2008. Presence and acquired origin of reduced recall for fear extinction in PTSD: Results of a twin study. J Psychiatry Res 42: 515-520.
30. Milad MR, Pitman RK, Ellis CB, Gold AL, Shin LM, Lasko NB, Zeidan MA, Handwerger K, Orr SP, Rauch SL. 2009. Neurobiological basis of failure to recall extinction memory in posttraumatic stress disorder. Biol Psychiatry 66: 1075-1082.
31. Mineka S, Oehlberg K. 2008. The relevance of recent developments in classical conditioning to understanding the etiology and maintenance of anxiety disorders. Acta Psychol (Amst) 127: 567-580.
32. Mineka S, Ohman A. 2002. Born to fear: Non-associative vs associative factors in the etiology of phobias. Behav Res Ther 40: 173-184.
33. Muigg P, Hetzenauer A, Hauer G, Hauschild M, Gaburro S, Frank E, Landgraf R, Singewald N. 2008. Impaired extinction of learned fear in rats selectively bred for high anxiety - evidence of altered neuronal processing in prefrontal-amygdala pathways. Eur J Neurosci 28: 2299-2309.
34. Nugent NR, Amstadter AB, Koenen KC. 2008. Genetics of post-traumatic stress disorder: Informing clinical conceptualizations and promoting future research. Am J Med Genet C 148C: 127-132.
35. Orr SP, Metzger LJ, Lasko NB, Macklin ML, Peri T, Pitman RK. 2000. De novo conditioning in trauma-exposed individuals with and without posttraumatic stress disorder. J Abnorm Psychol 109: 290-298. (Pubitemid 30616926)
36. Pape HC, Pare D. 2010. Plastic synaptic networks of the amygdala for the acquisition, expression, and extinction of conditioned fear. Physiol Rev 90: 419-463.
37. Peri T, Ben-Shakhar G, Orr SP, Shalev AY. 2000. Psychophysiologic assessment of aversive conditioning in posttraumatic stress disorder. Biol Psychiatry 47: 512-519. (Pubitemid 30129079)
38. Poulton R, Menzies RG. 2002. Non-associative fear acquisition: A review of the evidence from retrospective and longitudinal research. Behav Res Ther 40: 127-149.
39. Quirk GJ, Mueller D. 2008. Neural mechanisms of extinction learning and retrieval. Neuropsychopharmacology 33: 56-72.
40. Rauch SL, Shin LM, Phelps EA. 2006. Neurocircuitry models of post-traumatic stress disorder and extinction: Human neuroimaging research - past, present, and future. Biol Psychiatry 60: 376-382.
41. Rosario LA, Abercrombie ED. 1999. Individual differences in behavioral reactivity: Correlation with stress-induced norepinephrine efflux in the hippocampus of Sprague-Dawley rats. Brain Res Bull 48: 595-602.
42. Shin LM, Rauch SL, Pitman RK. 2006. Amygdala, medial prefrontal cortex, and hippocampal function in PTSD. Ann NY Acad Sci 1071: 67-79.
43. Siegmund A, Wotjak CT. 2006. Toward an animal model of posttraumatic stress disorder. Ann NY Acad Sci 1071: 324-334.
44. Sotres-Bayon F, Bush DE, LeDoux JE. 2007. Acquisition of fear extinction requires activation of NR2B-containing NMDA receptors in the lateral amygdala. Neuropsychopharmacology 32: 1929-1940.
45. Wellman CL, Izquierdo A, Garrett JE, Martin KP, Carroll J, Millstein R, Lesch KP, Murphy DL, Holmes A. 2007. Impaired stress-coping and fear extinction and abnormal corticolimbic morphology in serotonin transporter knock-out mice. J Neurosci 27: 684-691.
46. Yamamoto S, Morinobu S, Fuchikami M, Kurata A, Kozuru T, Yamawaki S. 2008. Effects of single prolonged stress and D-cycloserine on contextual fear extinction and hippocampal NMDA receptor expression in a rat model of PTSD. Neuropsychopharmacology 33: 2108-2116.
47. Yamamoto S, Morinobu S, Takei S, Fuchikami M, Matsuki A, Yamawaki S, Liberzon I. 2009. Single prolonged stress: Toward an animal model of posttraumatic stress disorder. Depress Anxiety 26: 1110-1117.
48. Zhang TY, Meaney MJ. 2010. Epigenetics and the environmental regulation of the genome and its function. Annu Rev Psychol 61: 439-466.