-
1
-
-
33750432183
-
Nuclear factor-kB and inhibitor of kB kinase pathways in oncogenic initiation and progression
-
Basseres DS, Baldwin AS. (2006). Nuclear factor-kB and inhibitor of kB kinase pathways in oncogenic initiation and progression. Oncogene 25: 6817-6830.
-
(2006)
Oncogene
, vol.25
, pp. 6817-6830
-
-
Basseres, D.S.1
Baldwin, A.S.2
-
2
-
-
0035902180
-
Oncogenic kinase signalling
-
Blume-Jensen P, Hunter T. (2001). Oncogenic kinase signalling. Nature 411: 355-365.
-
(2001)
Nature
, vol.411
, pp. 355-365
-
-
Blume-Jensen, P.1
Hunter, T.2
-
3
-
-
34547857049
-
The functional contrariety of JNK
-
Bode AM, Dong Z. (2007). The functional contrariety of JNK. Mol Carcinog 46: 591-598.
-
(2007)
Mol Carcinog
, vol.46
, pp. 591-598
-
-
Bode, A.M.1
Dong, Z.2
-
4
-
-
2342464085
-
The two NF-kB activation pathways and their role in innate and adaptive immunity
-
Bonizzi G, Karin M. (2004). The two NF-kB activation pathways and their role in innate and adaptive immunity. Trends Immunol 25: 280-288.
-
(2004)
Trends Immunol
, vol.25
, pp. 280-288
-
-
Bonizzi, G.1
Karin, M.2
-
5
-
-
0032980723
-
The Jun kinase 2 isoform is preferentially required for epidermal growth factor-induced transformation of human A549 lung carcinoma cells
-
Bost F, McKay R, Bost M, Potapova O, Dean NM, Mercola D. (1999). The Jun kinase 2 isoform is preferentially required for epidermal growth factor-induced transformation of human A549 lung carcinoma cells. Mol Cell Biol 19: 1938-1949.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 1938-1949
-
-
Bost, F.1
McKay, R.2
Bost, M.3
Potapova, O.4
Dean, N.M.5
Mercola, D.6
-
6
-
-
0033557839
-
Survey of gene amplifications during prostate cancer progression by high-throughout fluorescence in situ hybridization on tissue microarrays
-
Bubendorf L, Kononen J, Koivisto P, Schraml P, Moch H, Gasser TC et al. (1999). Survey of gene amplifications during prostate cancer progression by high-throughout fluorescence in situ hybridization on tissue microarrays. Cancer Res 59: 803-806.
-
(1999)
Cancer Res
, vol.59
, pp. 803-806
-
-
Bubendorf, L.1
Kononen, J.2
Koivisto, P.3
Schraml, P.4
Moch, H.5
Gasser, T.C.6
-
7
-
-
34249799899
-
Genome-wide analysis of gene expression in T cells to identify targets of the NF-kB transcription factor c-Rel
-
Bunting K, Rao S, Hardy K, Woltring D, Denyer GS, Wang J et al. (2007). Genome-wide analysis of gene expression in T cells to identify targets of the NF-kB transcription factor c-Rel. J Immunol 178: 7097-7109.
-
(2007)
J Immunol
, vol.178
, pp. 7097-7109
-
-
Bunting, K.1
Rao, S.2
Hardy, K.3
Woltring, D.4
Denyer, G.S.5
Wang, J.6
-
9
-
-
33644770221
-
The MYC oncogene in breast cancer progression: From benign epithelium to invasive carcinoma
-
Corzo C, Corominas JM, Tusquets I, Salido M, Bellet M, Fabregat X et al. (2006). The MYC oncogene in breast cancer progression: from benign epithelium to invasive carcinoma. Cancer Genet Cytogenet 165: 151-156.
-
(2006)
Cancer Genet Cytogenet
, vol.165
, pp. 151-156
-
-
Corzo, C.1
Corominas, J.M.2
Tusquets, I.3
Salido, M.4
Bellet, M.5
Fabregat, X.6
-
10
-
-
42949129074
-
Many roads lead to oncogene-induced senescence
-
Courtois-Cox S, Jones SL, Cichowski K. (2008). Many roads lead to oncogene-induced senescence. Oncogene 27: 2801-2809.
-
(2008)
Oncogene
, vol.27
, pp. 2801-2809
-
-
Courtois-Cox, S.1
Jones, S.L.2
Cichowski, K.3
-
12
-
-
33750475618
-
Current insights into the regulation of programmed cell death by NF-kB
-
Dutta J, Fan Y, Gupta N, Fan G, Gelinas C. (2006). Current insights into the regulation of programmed cell death by NF-kB. Oncogene 25: 6800-6816.
-
(2006)
Oncogene
, vol.25
, pp. 6800-6816
-
-
Dutta, J.1
Fan, Y.2
Gupta, N.3
Fan, G.4
Gelinas, C.5
-
13
-
-
0030011706
-
Selective activation of the proto-oncogene c-jun promoter by the transforming protein v-Rel
-
Fujii M, Minamino T, Nomura M, Miyamoto KI, Tanaka J, Seiki M. (1996). Selective activation of the proto-oncogene c-jun promoter by the transforming protein v-Rel. Oncogene 12: 2193-2202.
-
(1996)
Oncogene
, vol.12
, pp. 2193-2202
-
-
Fujii, M.1
Minamino, T.2
Nomura, M.3
Miyamoto, K.I.4
Tanaka, J.5
Seiki, M.6
-
14
-
-
0033596128
-
Multiple mutations contribute to the oncogeni-city of the retroviral oncoprotein v-Rel
-
Gilmore TD. (1999). Multiple mutations contribute to the oncogeni-city of the retroviral oncoprotein v-Rel. Oncogene 18: 6925-6937.
-
(1999)
Oncogene
, vol.18
, pp. 6925-6937
-
-
Gilmore, T.D.1
-
15
-
-
1842432464
-
The c-Rel transcription factor and B-cell proliferation: A deal with the devil
-
Gilmore TD, Kalaitzidis D, Liang MC, Starczynowski DT. (2004). The c-Rel transcription factor and B-cell proliferation: a deal with the devil. Oncogene 23: 2275-2286.
-
(2004)
Oncogene
, vol.23
, pp. 2275-2286
-
-
Gilmore, T.D.1
Kalaitzidis, D.2
Liang, M.C.3
Starczynowski, D.T.4
-
16
-
-
38849106942
-
Repression of B-cell linker (BLNK) and B-cell adaptor for phosphoinositide 3-kinase (BCAP) is important for lymphocyte transformation by rel proteins
-
Gupta N, Delrow J, Drawid A, Sengupta AM, Fan G, Gelinas C. (2008). Repression of B-cell linker (BLNK) and B-cell adaptor for phosphoinositide 3-kinase (BCAP) is important for lymphocyte transformation by rel proteins. Cancer Res 68: 808-814.
-
(2008)
Cancer Res
, vol.68
, pp. 808-814
-
-
Gupta, N.1
Delrow, J.2
Drawid, A.3
Sengupta, A.M.4
Fan, G.5
Gelinas, C.6
-
17
-
-
4444376712
-
Signaling to NF-kB
-
Hayden MS, Ghosh S. (2004). Signaling to NF-kB. Genes Dev 18: 2195-2224.
-
(2004)
Genes Dev
, vol.18
, pp. 2195-2224
-
-
Hayden, M.S.1
Ghosh, S.2
-
18
-
-
0032823313
-
Induction of interleukin-8 synthesis integrates effects on transcription and mRNA degradation from at least three different cytokine- or stress-activated signal transduc-tion pathways
-
Holtmann H, Winzen R, Holland P, Eickemeier S, Hoffmann E, Wallach D et al. (1999). Induction of interleukin-8 synthesis integrates effects on transcription and mRNA degradation from at least three different cytokine- or stress-activated signal transduc-tion pathways. Mol Cell Biol 19: 6742-6753.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 6742-6753
-
-
Holtmann, H.1
Winzen, R.2
Holland, P.3
Eickemeier, S.4
Hoffmann, E.5
Wallach, D.6
-
19
-
-
47349103884
-
Phospho-ERK staining is a poor indicator of the mutational status of BRAF and NRAS in human melanoma
-
Houben R, Vetter-Kauczok CS, Ortmann S, Rapp UR, Broecker EB, Becker JC. (2008). Phospho-ERK staining is a poor indicator of the mutational status of BRAF and NRAS in human melanoma. J Invest Dermatol 128: 2003-2012.
-
(2008)
J Invest Dermatol
, vol.128
, pp. 2003-2012
-
-
Houben, R.1
Vetter-Kauczok, C.S.2
Ortmann, S.3
Rapp, U.R.4
Broecker, E.B.5
Becker, J.C.6
-
20
-
-
31344472398
-
Genetic models of human cancer as a multistep process. Paradigm models of colorectal cancer, breast cancer, and chronic myelogenous and acute lymphoblastic leukaemia
-
Karakosta A, Golias C, Charalabopoulos A, Peschos D, Batistatou A, Charalabopoulos K. (2005). Genetic models of human cancer as a multistep process. Paradigm models of colorectal cancer, breast cancer, and chronic myelogenous and acute lymphoblastic leukaemia. J Exp Clin Cancer Res 24: 505-514.
-
(2005)
J Exp Clin Cancer Res
, vol.24
, pp. 505-514
-
-
Karakosta, A.1
Golias, C.2
Charalabopoulos, A.3
Peschos, D.4
Batistatou, A.5
Charalabopoulos, K.6
-
21
-
-
33745298519
-
Nuclear factor-kB in cancer development and progression
-
Karin M. (2006). Nuclear factor-kB in cancer development and progression. Nature 441: 431-436.
-
(2006)
Nature
, vol.441
, pp. 431-436
-
-
Karin, M.1
-
22
-
-
0037337694
-
Suppression of Ras-stimulated transformation by the JNK signal transduction pathway
-
Kennedy NJ, Sluss HK, Jones SN, Bar-Sagi D, Flavell RA, Davis RJ. (2003). Suppression of Ras-stimulated transformation by the JNK signal transduction pathway. Genes Dev 17: 629-637.
-
(2003)
Genes Dev
, vol.17
, pp. 629-637
-
-
Kennedy, N.J.1
Sluss, H.K.2
Jones, S.N.3
Bar-Sagi, D.4
Flavell, R.A.5
Davis, R.J.6
-
23
-
-
0031893017
-
AP-1 factors play an important role in transformation induced by the v-rel oncogene
-
Kralova J, Liss AS, Bargmann W, Bose Jr HR. (1998). AP-1 factors play an important role in transformation induced by the v-rel oncogene. Mol Cell Biol 18: 2997-3009.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 2997-3009
-
-
Kralova, J.1
Liss, A.S.2
Bargmann, W.3
Bose Jr., H.R.4
-
24
-
-
0029948788
-
Synergistic stimulation of avian IkBa transcription by rel and fos/ jun factors
-
Kralova J, Schatzle JD, Liss AS, Bargmann W, Bose Jr HR. (1996). Synergistic stimulation of avian IkBa transcription by rel and fos/ jun factors. Oncogene 12: 2595-2604.
-
(1996)
Oncogene
, vol.12
, pp. 2595-2604
-
-
Kralova, J.1
Schatzle, J.D.2
Liss, A.S.3
Bargmann, W.4
Bose Jr., H.R.5
-
25
-
-
0037230304
-
Activation of the JNK signaling pathway: Breaking the brake on apoptosis
-
Lin A. (2003). Activation of the JNK signaling pathway: breaking the brake on apoptosis. Bioessays 25: 17-24.
-
(2003)
Bioessays
, vol.25
, pp. 17-24
-
-
Lin, A.1
-
26
-
-
77956341456
-
Cell transformation by v-Rel reveals distinct roles of AP-1 family members in Rel/NF-kB oncogenesis
-
Liss AS, Tiwari R, Kralova J, Bose Jr HR. (2010). Cell transformation by v-Rel reveals distinct roles of AP-1 family members in Rel/NF-kB oncogenesis. Oncogene 29: 4925-4937.
-
(2010)
Oncogene
, vol.29
, pp. 4925-4937
-
-
Liss, A.S.1
Tiwari, R.2
Kralova, J.3
Bose Jr., H.R.4
-
27
-
-
32244438118
-
The suppression of SH3BGRL is important for v-Rel-mediated transformation
-
Majid SM, Liss AS, You M, Bose Jr HR. (2006). The suppression of SH3BGRL is important for v-Rel-mediated transformation. Oncogene 25: 756-768.
-
(2006)
Oncogene
, vol.25
, pp. 756-768
-
-
Majid, S.M.1
Liss, A.S.2
You, M.3
Bose Jr., H.R.4
-
28
-
-
0028141496
-
Transformation of mammalian cells by constitutively active MAP kinase kinase
-
Mansour SJ, Matten WT, Hermann AS, Candia JM, Rong S, Fukasawa K et al. (1994). Transformation of mammalian cells by constitutively active MAP kinase kinase. Science 265: 966-970.
-
(1994)
Science
, vol.265
, pp. 966-970
-
-
Mansour, S.J.1
Matten, W.T.2
Hermann, A.S.3
Candia, J.M.4
Rong, S.5
Fukasawa, K.6
-
29
-
-
34547209343
-
Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance
-
McCubrey JA, Steelman LS, Chappell WH, Abrams SL, Wong EW, Chang F et al. (2007). Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance. Biochim Biophys Acta 1773: 1263-1284.
-
(2007)
Biochim Biophys Acta
, vol.1773
, pp. 1263-1284
-
-
McCubrey, J.A.1
Steelman, L.S.2
Chappell, W.H.3
Abrams, S.L.4
Wong, E.W.5
Chang, F.6
-
30
-
-
33646336602
-
MAPK signal specificity: The right place at the right time
-
Murphy LO, Blenis J. (2006). MAPK signal specificity: the right place at the right time. Trends Biochem Sci 31: 268-275.
-
(2006)
Trends Biochem Sci
, vol.31
, pp. 268-275
-
-
Murphy, L.O.1
Blenis, J.2
-
31
-
-
0030612289
-
Differences in kB DNA-binding properties of v-Rel and c-Rel are the result of oncogenic mutations in three distinct functional regions of the Rel protein
-
Nehyba J, Hrdlickova R, Bose Jr HR. (1997). Differences in kB DNA-binding properties of v-Rel and c-Rel are the result of oncogenic mutations in three distinct functional regions of the Rel protein. Oncogene 14: 2881-2897.
-
(1997)
Oncogene
, vol.14
, pp. 2881-2897
-
-
Nehyba, J.1
Hrdlickova, R.2
Bose Jr., H.R.3
-
32
-
-
17344371391
-
Characterization of diverse viral vector preparations, using a simple and rapid whole-virion dot-blot method
-
Nelson DM, Wahlfors JJ, Chen L, Onodera M, Morgan RA. (1998). Characterization of diverse viral vector preparations, using a simple and rapid whole-virion dot-blot method. Hum Gene Ther 9: 2401-2405.
-
(1998)
Hum Gene Ther
, vol.9
, pp. 2401-2405
-
-
Nelson, D.M.1
Wahlfors, J.J.2
Chen, L.3
Onodera, M.4
Morgan, R.A.5
-
34
-
-
0025850381
-
Inhibition of jun transformation by a mutated fos gene: Design of an anti-oncogene
-
Okuno H, Suzuki T, Yoshida T, Hashimoto Y, Curran T, Iba H. (1991). Inhibition of jun transformation by a mutated fos gene: design of an anti-oncogene. Oncogene 6: 1491-1497.
-
(1991)
Oncogene
, vol.6
, pp. 1491-1497
-
-
Okuno, H.1
Suzuki, T.2
Yoshida, T.3
Hashimoto, Y.4
Curran, T.5
Iba, H.6
-
35
-
-
36049011859
-
Cooperation between JNK1 and JNK2 in activation of p53 apoptotic pathway
-
Oleinik NV, Krupenko NI, Krupenko SA. (2007). Cooperation between JNK1 and JNK2 in activation of p53 apoptotic pathway. Oncogene 26: 7222-7230.
-
(2007)
Oncogene
, vol.26
, pp. 7222-7230
-
-
Oleinik, N.V.1
Krupenko, N.I.2
Krupenko, S.A.3
-
37
-
-
63149194964
-
(V600E) BRAF is associated with disabled feedback inhibition of RAF-MEK signaling and elevated transcriptional output of the pathway
-
Pratilas CA, Taylor BS, Ye Q, Viale A, Sander C, Solit DB et al. (2009). (V600E)BRAF is associated with disabled feedback inhibition of RAF-MEK signaling and elevated transcriptional output of the pathway. Proc Natl Acad Sci USA 106: 4519-4524.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 4519-4524
-
-
Pratilas, C.A.1
Taylor, B.S.2
Ye, Q.3
Viale, A.4
Sander, C.5
Solit, D.B.6
-
38
-
-
34248597065
-
Differential regulation and properties of MAPKs
-
Raman M, Chen W, Cobb MH. (2007). Differential regulation and properties of MAPKs. Oncogene 26: 3100-3112.
-
(2007)
Oncogene
, vol.26
, pp. 3100-3112
-
-
Raman, M.1
Chen, W.2
Cobb, M.H.3
-
39
-
-
0032558692
-
A constitutively active and nuclear form of the MAP kinase ERK2 is sufficient for neurite outgrowth and cell transformation
-
Robinson MJ, Stippec SA, Goldsmith E, White MA, Cobb MH. (1998). A constitutively active and nuclear form of the MAP kinase ERK2 is sufficient for neurite outgrowth and cell transformation. Curr Biol 8: 1141-1150.
-
(1998)
Curr Biol
, vol.8
, pp. 1141-1150
-
-
Robinson, M.J.1
Stippec, S.A.2
Goldsmith, E.3
White, M.A.4
Cobb, M.H.5
-
41
-
-
0036098552
-
AP-1 as a regulator of cell life and death
-
Shaulian E, Karin M. (2002). AP-1 as a regulator of cell life and death. Nat Cell Biol 4: E131-E136.
-
(2002)
Nat Cell Biol
, vol.4
-
-
Shaulian, E.1
Karin, M.2
-
42
-
-
38949172004
-
MEK1 and MEK2 regulate distinct functions by sorting ERK2 to different intracellular compartments
-
Skarpen E, Flinder LI, Rosseland CM, Orstavik S, Wier0d L, Oksvold MP et al. (2008). MEK1 and MEK2 regulate distinct functions by sorting ERK2 to different intracellular compartments. FASEB J 22: 466-476.
-
(2008)
FASEB J
, vol.22
, pp. 466-476
-
-
Skarpen, E.1
Flinder, L.I.2
Rosseland, C.M.3
Orstavik, S.4
Wierod, L.5
Oksvold, M.P.6
-
43
-
-
0036738640
-
AP-1, NF-kB, and ERK activation thresholds for promotion of neoplastic transformation in the mouse epidermal JB6 model
-
Suzukawa K, Weber TJ, Colburn NH. (2002). AP-1, NF-kB, and ERK activation thresholds for promotion of neoplastic transformation in the mouse epidermal JB6 model. Environ Health Perspect 110: 865-870.
-
(2002)
Environ Health Perspect
, vol.110
, pp. 865-870
-
-
Suzukawa, K.1
Weber, T.J.2
Colburn, N.H.3
-
44
-
-
4143139997
-
SPRY2 is an inhibitor of the ras/extracellular signal-regulated kinase pathway in melanocytes and melanoma cells with wild-type BRAF but not with the V599E mutant
-
Tsavachidou D, Coleman ML, Athanasiadis G, Li S, Licht JD, Olson MF et al. (2004). SPRY2 is an inhibitor of the ras/extracellular signal-regulated kinase pathway in melanocytes and melanoma cells with wild-type BRAF but not with the V599E mutant. Cancer Res 64: 5556-5559.
-
(2004)
Cancer Res
, vol.64
, pp. 5556-5559
-
-
Tsavachidou, D.1
Coleman, M.L.2
Athanasiadis, G.3
Li, S.4
Licht, J.D.5
Olson, M.F.6
-
46
-
-
34248597048
-
Role of mitogen-activated protein kinase kinase 4 in cancer
-
Whitmarsh AJ, Davis RJ. (2007). Role of mitogen-activated protein kinase kinase 4 in cancer. Oncogene 26: 3172-3184.
-
(2007)
Oncogene
, vol.26
, pp. 3172-3184
-
-
Whitmarsh, A.J.1
Davis, R.J.2
-
49
-
-
30944447568
-
The extracellular signal-regulated kinase: Multiple substrates regulate diverse cellular functions
-
Yoon S, Seger R. (2006). The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions. Growth Factors 24: 21-44.
-
(2006)
Growth Factors
, vol.24
, pp. 21-44
-
-
Yoon, S.1
Seger, R.2
-
50
-
-
0032831780
-
The JNKK2-JNK1 fusion protein acts as a constitutively active c-Jun kinase that stimulates c-Jun transcription activity
-
Zheng C, Xiang J, Hunter T, Lin A. (1999). The JNKK2-JNK1 fusion protein acts as a constitutively active c-Jun kinase that stimulates c-Jun transcription activity. J Biol Chem 274: 28966-28971.
-
(1999)
J Biol Chem
, vol.274
, pp. 28966-28971
-
-
Zheng, C.1
Xiang, J.2
Hunter, T.3
Lin, A.4
|