메뉴 건너뛰기




Volumn 153, Issue 6, 2010, Pages 378-386

Proton-pump inhibitors are associated with increased cardiovascular risk independent of clopidogrel use: A nationwide cohort study

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ANTIDIABETIC AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CLOPIDOGREL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ESOMEPRAZOLE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LANSOPRAZOLE; LOOP DIURETIC AGENT; OMEPRAZOLE; PANTOPRAZOLE; PROTON PUMP INHIBITOR; RABEPRAZOLE; SPIRONOLACTONE; ANTITHROMBOCYTIC AGENT; DRUG DERIVATIVE; TICLOPIDINE;

EID: 77957372907     PISSN: 00034819     EISSN: 15393704     Source Type: Journal    
DOI: 10.7326/0003-4819-153-6-201009210-00005     Document Type: Article
Times cited : (239)

References (29)
  • 1
    • 34547655744 scopus 로고    scopus 로고
    • ACC/AHA 2007 guidelines for the management of patients with unstable angina/non-ST-Elevation myocardial infarction: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines for the Management of Patients with Unstable Angina/Non-ST-Elevation Myocardial Infarction)
    • PMID: 17692738
    • Anderson JL, Adams CD, Antman EM, Bridges CR, Califf RM, Casey DE Jr, et al. ACC/AHA 2007 guidelines for the management of patients with unstable angina/non-ST-Elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines for the Management of Patients With Unstable Angina/Non-ST-Elevation Myocardial Infarction) developed in collaboration with the American College of Emergency Physicians, the Society for Cardiovascular Angiography and Interventions, and the Society of Thoracic Surgeons endorsed by the American Association of Cardiovascular and Pulmonary Rehabilitation and the Society for Academic Emergency Medicine. J Am Coll Cardiol. 2007;50:e1-e157. [PMID: 17692738]
    • (2007) J Am Coll Cardiol , vol.50
    • Anderson, J.L.1    Adams, C.D.2    Antman, E.M.3    Bridges, C.R.4    Califf, R.M.5    Casey Jr., D.E.6
  • 2
    • 0037145863 scopus 로고    scopus 로고
    • Clopidogrel for the Reduction of Events during Observation. Early and sustained dual oral antiplatelet therapy following percutaneous coronary intervention: A randomized controlled trial
    • CREDO Investigators [PMID: 12435254]
    • Steinhubl SR, Berger PB, Mann JT 3rd, Fry ET, DeLago A, Wilmer C, et al; CREDO Investigators. Clopidogrel for the Reduction of Events During Observation. Early and sustained dual oral antiplatelet therapy following percutaneous coronary intervention: a randomized controlled trial. JAMA. 2002;288:2411-20. [PMID: 12435254]
    • (2002) JAMA , vol.288 , pp. 2411-2420
    • Steinhubl, S.R.1    Berger, P.B.2    Mann III, J.T.3    Fry, E.T.4    DeLago, A.5    Wilmer, C.6
  • 3
    • 0035899289 scopus 로고    scopus 로고
    • Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation
    • Clopidogrel in Unstable Angina to Prevent Recurrent Events Trial Investigators. [PMID: 11519503]
    • Yusuf S, Zhao F, Mehta SR, Chrolavicius S, Tognoni G, Fox KK; Clopidogrel in Unstable Angina to Prevent Recurrent Events Trial Investigators. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N Engl J Med. 2001;345:494-502. [PMID: 11519503]
    • (2001) N Engl J Med , vol.345 , pp. 494-502
    • Yusuf, S.1    Zhao, F.2    Mehta, S.R.3    Chrolavicius, S.4    Tognoni, G.5    Fox, K.K.6
  • 4
    • 33749339075 scopus 로고    scopus 로고
    • Cytochrome P450 2C19 loss-of-function polymorphism is a major determinant of clopidogrel responsiveness in healthy subjects
    • PMID: 16772608
    • Hulot JS, Bura A, Villard E, Azizi M, Remones V, Goyenvalle C, et al. Cytochrome P450 2C19 loss-of-function polymorphism is a major determinant of clopidogrel responsiveness in healthy subjects. Blood. 2006;108:2244-7. [PMID: 16772608]
    • (2006) Blood , vol.108 , pp. 2244-2247
    • Hulot, J.S.1    Bura, A.2    Villard, E.3    Azizi, M.4    Remones, V.5    Goyenvalle, C.6
  • 5
    • 0032807774 scopus 로고    scopus 로고
    • Review article: Cytochrome P450 and the metabolism of proton pump inhibitors - Emphasis on rabeprazole
    • PMID: 10491726
    • Ishizaki T, Horai Y. Review article: cytochrome P450 and the metabolism of proton pump inhibitors - emphasis on rabeprazole. Aliment Pharmacol Ther. 1999;13 Suppl 3:27-36. [PMID: 10491726]
    • (1999) Aliment Pharmacol Ther , vol.13 , Issue.SUPPL. 3 , pp. 27-36
    • Ishizaki, T.1    Horai, Y.2
  • 6
    • 38349065084 scopus 로고    scopus 로고
    • Influence of omeprazole on the antiplatelet action of clopidogrel associated with aspirin: The randomized, double-blind OCLA (Omeprazole CLopidogrel Aspirin) study
    • PMID: 18206732
    • Gilard M, Arnaud B, Cornily JC, Le Gal G, Lacut K, Le Calvez G, et al. Influence of omeprazole on the antiplatelet action of clopidogrel associated with aspirin: the randomized, double-blind OCLA (Omeprazole CLopidogrel Aspirin) study. J Am Coll Cardiol. 2008;51:256-60. [PMID: 18206732]
    • (2008) J Am Coll Cardiol , vol.51 , pp. 256-260
    • Gilard, M.1    Arnaud, B.2    Cornily, J.C.3    Le Gal, G.4    Lacut, K.5    Le Calvez, G.6
  • 7
    • 33750079553 scopus 로고    scopus 로고
    • Influence of omeprazol on the antiplatelet action of clopidogrel associated to aspirin
    • [Letter]. [PMID: 16898956]
    • Gilard M, Arnaud B, Le Gal G, Abgrall JF, Boschat J. Influence of omeprazol on the antiplatelet action of clopidogrel associated to aspirin [Letter]. J Thromb Haemost. 2006;4:2508-9. [PMID: 16898956]
    • (2006) J Thromb Haemost , vol.4 , pp. 2508-2509
    • Gilard, M.1    Arnaud, B.2    Le Gal, G.3    Abgrall, J.F.4    Boschat, J.5
  • 8
    • 76449083482 scopus 로고    scopus 로고
    • Effect of comedication with proton pump inhibitors (PPIs) on post-interventional residual platelet aggregation in patients undergoing coronary stenting treated by dual antiplatelet therapy
    • PMID: 19781742
    • Zuern CS, Geisler T, Lutilsky N, Winter S, Schwab M, Gawaz M. Effect of comedication with proton pump inhibitors (PPIs) on post-interventional residual platelet aggregation in patients undergoing coronary stenting treated by dual antiplatelet therapy. Thromb Res. 2010;125:e51-4. [PMID: 19781742]
    • (2010) Thromb Res , vol.125
    • Zuern, C.S.1    Geisler, T.2    Lutilsky, N.3    Winter, S.4    Schwab, M.5    Gawaz, M.6
  • 9
    • 62649164844 scopus 로고    scopus 로고
    • A population-based study of the drug interaction between proton pump inhibitors and clopidogrel
    • PMID: 19176635
    • Juurlink DN, Gomes T, Ko DT, Szmitko PE, Austin PC, Tu JV, et al. A population-based study of the drug interaction between proton pump inhibitors and clopidogrel. CMAJ. 2009;180:713-8. [PMID: 19176635]
    • (2009) CMAJ , vol.180 , pp. 713-718
    • Juurlink, D.N.1    Gomes, T.2    Ko, D.T.3    Szmitko, P.E.4    Austin, P.C.5    Tu, J.V.6
  • 10
    • 61549124132 scopus 로고    scopus 로고
    • Risk of adverse outcomes associated with concomitant use of clopidogrel and proton pump inhibitors following acute coronary syndrome
    • PMID: 19258584
    • Ho PM, Maddox TM, Wang L, Fihn SD, Jesse RL, Peterson ED, et al. Risk of adverse outcomes associated with concomitant use of clopidogrel and proton pump inhibitors following acute coronary syndrome. JAMA. 2009;301:937-44. [PMID: 19258584]
    • (2009) JAMA , vol.301 , pp. 937-944
    • Ho, P.M.1    Maddox, T.M.2    Wang, L.3    Fihn, S.D.4    Jesse, R.L.5    Peterson, E.D.6
  • 11
    • 64849116567 scopus 로고    scopus 로고
    • Abstract 3999: Baseline proton pump inhibitor use is associated with increased cardiovascular events with and without the use of clopidogrel in the CREDO Trial
    • Dunn SP, Macaulay TE, Brennan DM, Campbell CL, Charnigo RJ, Smyth SS, et al. Abstract 3999: Baseline proton pump inhibitor use is associated with increased cardiovascular events with and without the use of clopidogrel in the CREDO Trial. Circulation. 2008;118:S815.
    • (2008) Circulation , vol.118
    • Dunn, S.P.1    Macaulay, T.E.2    Brennan, D.M.3    Campbell, C.L.4    Charnigo, R.J.5    Smyth, S.S.6
  • 12
    • 70249139788 scopus 로고    scopus 로고
    • Pharmacodynamic effect and clinical efficacy of clopidogrel and prasugrel with or without a proton-pump inhibitor: An analysis of two randomised trials
    • PMID: 19726078
    • O'Donoghue ML, Braunwald E, Antman EM, Murphy SA, Bates ER, Rozenman Y, et al. Pharmacodynamic effect and clinical efficacy of clopidogrel and prasugrel with or without a proton-pump inhibitor: an analysis of two randomised trials. Lancet. 2009;374:989-97. [PMID: 19726078]
    • (2009) Lancet , vol.374 , pp. 989-997
    • O'Donoghue, M.L.1    Braunwald, E.2    Antman, E.M.3    Murphy, S.A.4    Bates, E.R.5    Rozenman, Y.6
  • 13
    • 77950895115 scopus 로고    scopus 로고
    • Outcomes with concurrent use of clopidogrel and proton-pump inhibitors: A cohort study
    • PMID: 20231564
    • Ray WA, Murray KT, Griffin MR, Chung CP, Smalley WE, Hall K, et al. Outcomes with concurrent use of clopidogrel and proton-pump inhibitors: a cohort study. Ann Intern Med. 2010;152:337-45. [PMID: 20231564]
    • (2010) Ann Intern Med , vol.152 , pp. 337-345
    • Ray, W.A.1    Murray, K.T.2    Griffin, M.R.3    Chung, C.P.4    Smalley, W.E.5    Hall, K.6
  • 14
    • 70249116131 scopus 로고    scopus 로고
    • Silver Spring, MD: U.S. Food and Drug Administration; Accessed at on 27 July 2010
    • U.S. Food and Drug Administration. Early Communication About an Ongoing Safety Review of Clopidogrel Bisulfate (Marketed as Plavix). Silver Spring, MD: U.S. Food and Drug Administration; 2009. Accessed at www.fda.gov/Drugs/ DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ DrugSafetyInformationforHeathcareProfessionals/ucm079520.htm on 27 July 2010.
    • (2009) Early Communication about An Ongoing Safety Review of Clopidogrel Bisulfate (Marketed As Plavix)
  • 17
    • 15144344551 scopus 로고    scopus 로고
    • The Danish prescription registries
    • PMID: 9377907
    • Gaist D, Sørensen HT, Hallas J. The Danish prescription registries. Dan Med Bull. 1997;44:445-8. [PMID: 9377907]
    • (1997) Dan Med Bull , vol.44 , pp. 445-448
    • Gaist, D.1    Sørensen, H.T.2    Hallas, J.3
  • 18
    • 56849095254 scopus 로고    scopus 로고
    • Initiation and persistence with clopidogrel treatment after acute myocardial infarction: A nationwide study
    • PMID: 18823305
    • Sørensen R, Gislason GH, Fosbøl EL, Rasmussen S, Køber L, Madsen JK, et al. Initiation and persistence with clopidogrel treatment after acute myocardial infarction: a nationwide study. Br J Clin Pharmacol. 2008;66:875-84. [PMID: 18823305]
    • (2008) Br J Clin Pharmacol , vol.66 , pp. 875-884
    • Sørensen, R.1    Gislason, G.H.2    Fosbøl, E.L.3    Rasmussen, S.4    Køber, L.5    Madsen, J.K.6
  • 19
    • 0037296498 scopus 로고    scopus 로고
    • The validity of the diagnosis of acute myocardial infarction in routine statistics: A comparison of mortality and hospital discharge data with the Danish MONICA registry
    • PMID: 12654406
    • Madsen M, Davidsen M, Rasmussen S, Abildstrom SZ, Osler M. The validity of the diagnosis of acute myocardial infarction in routine statistics: a comparison of mortality and hospital discharge data with the Danish MONICA registry. J Clin Epidemiol. 2003;56:124-30. [PMID: 12654406]
    • (2003) J Clin Epidemiol , vol.56 , pp. 124-130
    • Madsen, M.1    Davidsen, M.2    Rasmussen, S.3    Abildstrom, S.Z.4    Osler, M.5
  • 20
    • 34548361895 scopus 로고    scopus 로고
    • Validity of stroke diagnoses in a National Register of Patients
    • PMID: 17478969
    • Krarup LH, Boysen G, Janjua H, Prescott E, Truelsen T. Validity of stroke diagnoses in a National Register of Patients. Neuroepidemiology. 2007;28:150-4. [PMID: 17478969]
    • (2007) Neuroepidemiology , vol.28 , pp. 150-154
    • Krarup, L.H.1    Boysen, G.2    Janjua, H.3    Prescott, E.4    Truelsen, T.5
  • 21
    • 0035869582 scopus 로고    scopus 로고
    • Development and validation of the Ontario acute myocardial infarction mortality prediction rules
    • PMID: 11263626
    • Tu JV, Austin PC, Walld R, Roos L, Agras J, McDonald KM. Development and validation of the Ontario acute myocardial infarction mortality prediction rules. J Am Coll Cardiol. 2001;37:992-7. [PMID: 11263626]
    • (2001) J Am Coll Cardiol , vol.37 , pp. 992-997
    • Tu, J.V.1    Austin, P.C.2    Walld, R.3    Roos, L.4    Agras, J.5    McDonald, K.M.6
  • 22
    • 26644463417 scopus 로고    scopus 로고
    • Hospital variation in mortality after first acute myocardial infarction in Denmark from 1995 to 2002: Lower short-term and 1-year mortality in high-volume and specialized hospitals
    • PMID: 16166866
    • Rasmussen S, Zwisler AD, Abildstrom SZ, Madsen JK, Madsen M. Hospital variation in mortality after first acute myocardial infarction in Denmark from 1995 to 2002: lower short-term and 1-year mortality in high-volume and specialized hospitals. Med Care. 2005;43:970-8. [PMID: 16166866]
    • (2005) Med Care , vol.43 , pp. 970-978
    • Rasmussen, S.1    Zwisler, A.D.2    Abildstrom, S.Z.3    Madsen, J.K.4    Madsen, M.5
  • 23
    • 33747125484 scopus 로고    scopus 로고
    • Risk of death or reinfarction associated with the use of selective cyclooxygenase-2 inhibitors and nonselective nonsteroidal antiinflammatory drugs after acute myocardial infarction
    • DOI 10.1161/CIRCULATIONAHA.106.616219, PII 0000301720060627000010
    • Gislason GH, Jacobsen S, Rasmussen JN, Rasmussen S, Buch P, Friberg J, et al. Risk of death or reinfarction associated with the use of selective cyclooxygenase-2 inhibitors and nonselective nonsteroidal antiinflammatory drugs after acute myocardial infarction. Circulation. 2006;113:2906-13. [PMID: 16785336] (Pubitemid 44297231)
    • (2006) Circulation , vol.113 , Issue.25 , pp. 2906-2913
    • Gislason, G.H.1    Jacobsen, S.2    Rasmussen, J.N.3    Rasmussen, S.4    Buch, P.5    Friberg, J.6    Schramm, T.K.7    Abildstrom, S.Z.8    Kober, L.9    Madsen, M.10    Torp-Pedersen, C.11
  • 24
    • 33744495314 scopus 로고    scopus 로고
    • Sensitivity analysis and external adjustment for unmeasured confounders in epidemiologic database studies of therapeutics
    • DOI 10.1002/pds.1200
    • Schneeweiss S. Sensitivity analysis and external adjustment for unmeasured confounders in epidemiologic database studies of therapeutics. Pharmacoepidemiol Drug Saf. 2006;15:291-303. [PMID: 16447304] (Pubitemid 43797117)
    • (2006) Pharmacoepidemiology and Drug Safety , vol.15 , Issue.5 , pp. 291-303
    • Schneeweiss, S.1
  • 25
    • 73449122247 scopus 로고    scopus 로고
    • Cardiovascular outcomes and mortality in patients using clopidogrel with proton pump inhibitors after percutaneous coronary intervention or acute coronary syndrome
    • PMID: 19933932
    • Rassen JA, Choudhry NK, Avorn J, Schneeweiss S. Cardiovascular outcomes and mortality in patients using clopidogrel with proton pump inhibitors after percutaneous coronary intervention or acute coronary syndrome. Circulation. 2009;120:2322-9. [PMID: 19933932]
    • (2009) Circulation , vol.120 , pp. 2322-2329
    • Rassen, J.A.1    Choudhry, N.K.2    Avorn, J.3    Schneeweiss, S.4
  • 27
    • 70450237790 scopus 로고    scopus 로고
    • Upper gastrointestinal bleeding in patients receiving dual antiplatelet therapy after coronary stenting
    • PMID: 19797827
    • Yasuda H, Yamada M, Sawada S, Endo Y, Inoue K, Asano F, et al. Upper gastrointestinal bleeding in patients receiving dual antiplatelet therapy after coronary stenting. Intern Med. 2009;48:1725-30. [PMID: 19797827]
    • (2009) Intern Med , vol.48 , pp. 1725-1730
    • Yasuda, H.1    Yamada, M.2    Sawada, S.3    Endo, Y.4    Inoue, K.5    Asano, F.6
  • 28
    • 58749090547 scopus 로고    scopus 로고
    • Genetic determinants of response to clopidogrel and cardiovascular events
    • French Registry of Acute ST-Elevation and Non-ST-Elevation Myocardial Infarction (FAST-MI) Investigators. [PMID: 19106083]
    • Simon T, Verstuyft C, Mary-Krause M, Quteineh L, Drouet E, Méneveau N, et al; French Registry of Acute ST-Elevation and Non-ST-Elevation Myocardial Infarction (FAST-MI) Investigators. Genetic determinants of response to clopidogrel and cardiovascular events. N Engl J Med. 2009;360:363-75. [PMID: 19106083]
    • (2009) N Engl J Med , vol.360 , pp. 363-375
    • Simon, T.1    Verstuyft, C.2    Mary-Krause, M.3    Quteineh, L.4    Drouet, E.5    Méneveau, N.6
  • 29
    • 67649645191 scopus 로고    scopus 로고
    • Genetic variation of CYP2C19 affects both pharmacokinetic and pharmacodynamic responses to clopidogrel but not prasugrel in aspirin-treated patients with coronary artery disease
    • PMID: 19429918
    • Varenhorst C, James S, Erlinge D, Brandt JT, Braun OO, Man M, et al. Genetic variation of CYP2C19 affects both pharmacokinetic and pharmacodynamic responses to clopidogrel but not prasugrel in aspirin-treated patients with coronary artery disease. Eur Heart J. 2009;30:1744-52. [PMID: 19429918]
    • (2009) Eur Heart J , vol.30 , pp. 1744-1752
    • Varenhorst, C.1    James, S.2    Erlinge, D.3    Brandt, J.T.4    Braun, O.O.5    Man, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.