Reduced expression and activation of voltage-gated sodium channels contributes to blunted baroreflex sensitivity in heart failure rats

Journal of Neuroscience Research

Volumn 88, Issue 15, 2010, Pages 3337-3349

  Tu, Huiyin ^a   Zhang, Libin ^a   Tran, Thai P ^a   Muelleman, Robert L ^a   Li, Yu Long ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Aortic baroreceptor neuron; Baroreex; Heart failure; Sodium channel

Indexed keywords

MESSENGER RNA; VOLTAGE GATED SODIUM CHANNEL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTIC BAROREFLEX SENSITIVITY; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY LIGATION; HEART FAILURE; MALE; NERVE CELL EXCITABILITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REFLEX; REFLEX DISORDER; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ACTION POTENTIALS; ANIMALS; AORTA; BAROREFLEX; BLOTTING, WESTERN; FLUORESCENT ANTIBODY TECHNIQUE; HEART FAILURE; MALE; NEURONS; PATCH-CLAMP TECHNIQUES; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SODIUM CHANNELS;

EID: 78649438756     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.22483     Document Type: Article

References (59)

1. Arbuckle JB, Docherty RJ. 1995. Expression of tetrodotoxin-resistant sodium channels in capsaicin-sensitive dorsal root ganglion neurons of adult rats. Neurosci Lett 185:70-73.
2. + channels in pain pathways. Trends Pharmacol Sci 22:27-31.
3. Binkley PF, Nunziata E, Haas GJ, Nelson SD, Cody RJ. 1991. Parasympathetic withdrawal is an integral component of autonomic imbalance in congestive heart failure: demonstration in human subjects and verification in a paced canine model of ventricular failure. J Am Coll Cardiol 18:464-472.
4. Browning KN. 2003. Excitability of nodose ganglion cells and their role in vago-vagal reflex control of gastrointestinal function. Curr Opin Pharmacol 3:613-617.
5. Caffrey JM, Eng DL, Black JA, Waxman SG, Kocsis JD. 1992. Three types of sodium channels in adult rat dorsal root ganglion neurons. Brain Res 592:283-297.
6. Catterall WA, Goldin AL, Waxman SG. 2005. International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels. Pharmacol Rev 57:397-409.
7. Creager MA, Creager SJ. 1994. Arterial baroreflex regulation of blood pressure in patients with congestive heart failure. J Am Coll Cardiol 23:401-405.
8. Cummins TR, Sheets PL, Waxman SG. 2007. The roles of sodium channels in nociception: implications for mechanisms of pain. Pain 131:243-257.
9. Devor M. 1999. Unexplained peculiarities of the dorsal root ganglion. Pain Suppl 6:S27-S35.
10. Dibner-Dunlap ME, Thames MD. 1989. Baroreflex control of renal sympathetic nerve activity is preserved in heart failure despite reduced arterial baroreceptor sensitivity. Circ Res 65:1526-1535.
11. Ducreux C, Reynaud JC, Puizillout JJ. 1993. Spike conduction properties of T-shaped C neurons in the rabbit nodose ganglion. Pflugers Arch 424:238-244.
12. Fan W, Andresen MC. 1998. Differential frequency-dependent reflex integration of myelinated and nonmyelinated rat aortic baroreceptors. Am J Physiol 275:H632-H640.
13. Fan W, Reynolds PJ, Andresen MC. 1996. Baroreflex frequencyresponse characteristics to aortic depressor and carotid sinus nerve stimulation in rats. Am J Physiol 271:H2218-H2227.
14. Floras JS. 1993. Clinical aspects of sympathetic activation and parasympathetic withdrawal in heart failure. J Am Coll Cardiol 22:72A-84A.
15. Frenneaux MP. 2004. Autonomic changes in patients with heart failure and in post-myocardial infarction patients. Heart 90:1248-1255.
16. 2+ currents of acutely isolated adult rat nodose ganglion cells. J Neurophysiol 55:527-539.
17. Kleiger RE, Miller JP, Bigger JT Jr, Moss AJ. 1987. Decreased heart rate variability and its association with increased mortality after acute myocardial infarction. Am J Cardiol 59:256-262.
18. Kobayashi M, Cheng ZB, Tanaka K, Nosaka S. 1999. Is the aortic depressor nerve involved in arterial chemoreflexes in rats? J Auton Nerv Syst 78:38-48.
19. Kwong K, Carr MJ, Gibbard A, Savage TJ, Singh K, Jing J, Meeker S, Undem BJ. 2008. Voltage-gated sodium channels in nociceptive versus non-nociceptive nodose vagal sensory neurons innervating guinea pig lungs. J Physiol 586:1321-1336.
20. Li YL, Xia XH, Zheng H, Gao L, Li YF, Liu D, Patel KP, Wang W, Schultz HD. 2006. Angiotensin II enhances carotid body chemoreflex control of sympathetic outflow in chronic heart failure rabbits. Cardiovasc Res 71:129-138.
21. Li YL, Tran TP, Muelleman R, Schultz HD. 2008. Blunted excitability of aortic baroreceptor neurons in diabetic rats: involvement of hyperpolarization-activated channel. Cardiovasc Res 79:715-721.
22. + current in aortic baroreceptor neurones of rats. J Physiol 501:275-287.
23. -Delta Delta C(T) method. Methods 25:402-408.
24. + currents mediate action potential electrogenesis in small neurons of mouse dorsal root ganglia. Pflugers Arch 453:83-96.
25. Obias-Manno D, Wijetunga M. 2004. Risk stratification and primary prevention of sudden cardiac death: sudden death prevention. AACN Clin Issues 15:404-418.
26. v1.8 maintain action potential amplitude in small DRG neurons in the context of depolarization. Mol Pain 3:12.
27. Perry MJ, Lawson SN, Robertson J. 1991. Neurofilament immunoreactivity in populations of rat primary afferent neurons: a quantitative study of phosphorylated and non-phosphorylated subunits. J Neurocytol 20:746-758.
28. Pinna GD, Maestri R, Capomolla S, Febo O, Robbi E, Cobelli F, La Rovere MT. 2005. Applicability and clinical relevance of the transfer function method in the assessment of baroreflex sensitivity in heart failure patients. J Am Coll Cardiol 46:1314-1321.
29. v1.9 is required for inflammation-based urinary bladder dysfunction. Neurosci Lett 452:28-32.
30. Roig E, Perez-Villa F, Morales M, Jimenez W, Orus J, Heras M, Sanz G. 2000. Clinical implications of increased plasma angiotensin II despite ACE inhibitor therapy in patients with congestive heart failure. Eur Heart J 21:53-57.
31. Rondon E, Brasileiro-Santos MS, Moreira ED, Rondon MU, Mattos KC, Coelho MA, Silva GJ, Brum PC, Fiorino P, Irigoyen MC, Krieger EM, Middlekauff HR, Negrao CE. 2006. Exercise training improves aortic depressor nerve sensitivity in rats with ischemiainduced heart failure. Am J Physiol Heart Circ Physiol 291:H2801-H2806.
32. Rosamond W, Flegal K, Furie K, Go A, Greenlund K, Haase N, Hailpern SM, Ho M, Howard V, Kissela B, Kittner S, Lloyd-Jones D, McDermott M, Meigs J, Moy C, Nichol G, O'Donnell C, Roger V, Sorlie P, Steinberger J, Thom T, Wilson M, Hong Y. 2008. Heart disease and stroke statistics-2008 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 117:e25-e146.
33. Ruttanaumpawan P, Gilman MP, Usui K, Floras JS, Bradley TD. 2008. Sustained effect of continuous positive airway pressure on baroreflex sensitivity in congestive heart failure patients with obstructive sleep apnea. J Hypertens 26:1163-1168.
34. Salgado HC, Barale AR, Castania JA, Machado BH, Chapleau MW, Fazan R Jr. 2007. Baroreflex responses to electrical stimulation of aortic depressor nerve in conscious SHR. Am J Physiol Heart Circ Physiol 292:H593-H600.
35. Sapru HN, Gonzalez E, Krieger AJ. 1981. Aortic nerve stimulation in the rat: cardiovascular and respiratory responses. Brain Res Bull 6:393-398.
36. Sapru HN, Krieger AJ. 1977. Carotid and aortic chemoreceptor function in the rat. J Appl Physiol 42:344-348.
37. + current heterogeneity in rat nodose neurons and its impact on neuronal discharge. J Neurophysiol 78:3198-3209.
38. Schild JH, Clark JW, Hay M, Mendelowitz D, Andresen MC, Kunze DL. 1994. A-and C-type rat nodose sensory neurons: model interpretations of dynamic discharge characteristics. J Neurophysiol 71:2338-2358.
39. Schunkert H, Tang SS, Litwin SE, Diamant D, Riegger G, Dzau VJ, Ingelfinger JR. 1993. Regulation of intrarenal and circulating renin-angiotensin systems in severe heart failure in the rat. Cardiovasc Res 27:731-735.
40. Shang LL, Sanyal S, Pfahnl AE, Jiao Z, Allen J, Liu H, Dudley SC Jr. 2008. NF-kappaB-dependent transcriptional regulation of the cardiac scn5a sodium channel by angiotensin II. Am J Physiol Cell Physiol 294:C372-C379.
41. Shen W, Gill RM, Zhang JP, Jones BD, Corbly AK, Steinberg MI. 2005. Sodium channel enhancer restores baroreflex sensitivity in conscious dogs with heart failure. Am J Physiol Heart Circ Physiol 288:H1508-H1514.
42. Tang X, Dworkin BR. 2007. Baroreflexes of the rat. V. Tetanus-induced potentiation of ADN A-fiber responses at the NTS. Am J Physiol Regul Integr Comp Physiol 293:R2254-R2259.
43. Tate S, Benn S, Hick C, Trezise D, John V, Mannion RJ, Costigan M, Plumpton C, Grose D, Gladwell Z, Kendall G, Dale K, Bountra C, Woolf CJ. 1998. Two sodium channels contribute to the TTX-R sodium current in primary sensory neurons. Nat Neurosci 1:653-655.
44. Touyz RM, Berry C. 2002. Recent advances in angiotensin II signaling. Braz J Med Biol Res 35:1001-1015.
45. Wang H, Rivero-Melian C, Robertson B, Grant G. 1994. Transganglionic transport and binding of the isolectin B4 from Griffonia simplicifolia I in rat primary sensory neurons. Neuroscience 62:539-551.
46. Wang W, Chen JS, Zucker IH. 1990. Carotid sinus baroreceptor sensitivity in experimental heart failure. Circulation 81:1959-1966.
47. Wang W, Chen JS, Zucker IH. 1991a. Carotid sinus baroreceptor reflex in dogs with experimental heart failure. Circ Res 68:1294-1301.
48. Wang W, Chen JS, Zucker IH. 1991b. Postexcitatory depression of baroreceptors in dogs with experimental heart failure. Am J Physiol 260:H1160-H1165.
49. Wang W, Han HY, Zucker IH. 1996. Depressed baroreflex in heart failure is not due to structural change in carotid sinus nerve fibers. J Auton Nerv Syst 57:101-108.
50. Waxman SG, Dib-Hajj S, Cummins TR, Black JA. 1999. Sodium channels and pain. Proc Natl Acad Sci U S A 96:7635-7639.
51. White CW. 1981. Abnormalities in baroreflex control of heart rate in canine heart failure. Am J Physiol 240:H793-H799.
52. Yoshida S. 1994. Tetrodotoxin-resistant sodium channels. Cell Mol Neurobiol 14:227-244.
53. Yu FH, Catterall WA. 2003. Overview of the voltage-gated sodium channel family. Genome Biol 4:207.
54. Zhang GX, Lu XM, Kimura S, Nishiyama A. 2007. Role of mitochondria in angiotensin II-induced reactive oxygen species and mitogenactivated protein kinase activation. Cardiovasc Res 76:204-212.
55. Zheng H, Li YF, Zucker IH, Patel KP. 2006. Exercise training improves renal excretory responses to acute volume expansion in rats with heart failure. Am J Physiol Renal Physiol 291:F1148-F1156.
56. Zhu GQ, Gao L, Li Y, Patel KP, Zucker IH, Wang W. 2004. AT1 receptor mRNA antisense normalizes enhanced cardiac sympathetic afferent reflex in rats with chronic heart failure. Am J Physiol Heart Circ Physiol 287:H1828-H1835.
57. Zucker IH, Liu JL. 2000. Angiotensin II-nitric oxide interactions in the control of sympathetic outflow in heart failure. Heart Fail Rev 5:27-43.
58. Zucker IH, Wang W, Brandle M, Schultz HD, Patel KP. 1995. Neural regulation of sympathetic nerve activity in heart failure. Prog Cardiovasc Dis 37:397-414.
59. Zucker IH, Hackley JF, Cornish KG, Hiser BA, Anderson NR, Kieval R, Irwin ED, Serdar DJ, Peuler JD, Rossing MA. 2007. Chronic baroreceptor activation enhances survival in dogs with pacing-induced heart failure. Hypertension 50:904-910.