Inactivation properties of sodium channel Nav1.8 maintain action potential amplitude in small DRG neurons in the context of depolarization

Molecular Pain

Volumn 3, Issue , 2007, Pages

  Harty, T Patrick ^a,b   Waxman, Stephen G ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VA CONNECTICUT HEALTHCARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; POTASSIUM CHANNEL BLOCKING AGENT; TETRODOTOXIN; VOLTAGE GATED SODIUM CHANNEL;

AMPLITUDE MODULATION; ANIMAL CELL; ARTICLE; CELL MEMBRANE DEPOLARIZATION; CONTROLLED STUDY; FEMALE; GENETIC TRANSFECTION; HYPERPOLARIZATION; MALE; MEMBRANE ELECTROPHYSIOLOGY; MOUSE; NERVE CELL CULTURE; NERVE CELL MEMBRANE POTENTIAL; NERVE FIBER; NERVE PROJECTION; NONHUMAN; PRIORITY JOURNAL; SPINAL CORD DORSAL HORN; SPINAL GANGLION; STEADY STATE; VOLTAGE CLAMP; WAVEFORM; WILD TYPE;

EID: 34250618329     PISSN: 17448069     EISSN: None     Source Type: Journal    
DOI: 10.1186/1744-8069-3-12     Document Type: Article

References (37)

1. Svoboda J Motin V Hájek I Syková E Increase in extracellular potassium level in rat spinal dorsal horn induced by noxious stimulation and peripheral injury Brain Res 1988 458 97-105 10.1016/0006-8993(88)90500-8 3208102
2. Vyklický L Syková E Kříž N Ujec E Post-stimulation changes of extracellular potassium concenteration in the spinal cord of the rat Brain Res 1972 45 608-611 10.1016/ 0006-8993(72)90492-1 4343681
3. Wall PD Control of impulse conduction in long range branches of afferents by increases and decreases of primary afferent depolarization in the rat Eur J Neurosci 1994 6 1136-1142 10.1111/ j.1460-9568.1994.tb00611.x 7952294
4. Malenka RC Kocsis JD Ransom BR Waxman SG Modulation of parallel fiber excitability by postsynaptically mediated changes in extracellular potassium Science 1981 214 339-341 10.1126/science.7280695 7280695
5. Black JA Dib-Hajj S McNabola K Jeste S Rizzo MA Kocsis JD Waxman SG Spinal sensory neurons express multiple sodium channel alpha-subunit mRNAs Mol Brain Res 1996 43 117-131 10.1016/S0169-328X(96)00163-5 9037525
6. Akopian AN Sivilotti L Wood JN A tetrodotoxin-resistant voltage-gated sodium channel expressed by sensory neurons Nature 1996 379 257-262 10.1038/379257a0 8538791
7. Sangameswaran L Delgado SG Fish LM Koch BD Jakeman LB Stewart GR Sze P Hunter JC Eglen RM Herman RC Structure and function of a novel voltage-gated, tetrodotoxin-resistant sodium channel specific to sensory neurons J Biol Chem 1996 271 5953-5956 10.1074/jbc.271.11.5953 8626372
8. Dib-Hajj S Black JA Cummins TR Waxman SG NaN/Nav1.9: A sodium channel with unique properties Trends Neurosci 2002 25 253-259 10.1016/ S0166-2236(02)02150-1 11972962
9. Caffrey JM Eng DL Black JA Waxman SG Kocsis JD Three types of sodium channels in adult rat dorsal root ganglion neurons Brain Res 1992 592 283-297 10.1016/0006-8993(92)91687-A 1280518
10. Elliott AA Elliott JR Characterization of TTX-sensitive and TTX-resistant sodium currents in small cells from adult rat dorsal root ganglia J Physiol 1993 463 39-56 1175332 8246189
11. Kostyuk PG Veselovsky NS Tsyndrenko AY Ionic currents in the somatic membrane of rat dorsal root ganglion neurons-I. Sodium currents Neuroscience 1981 6 2423-2430 10.1016/0306-4522(81)90088-9 6275294
12. Roy ML Narahashi T Differential properties of tetrodotoxin-sensitive and tetrodotoxin-resistant sodium channels in rat dorsal root ganglion neurons J Neurosci 1992 12 2104-2111 1318956
13. Ogata N Tatebayashi H Kinetic analysis of two types of Na+ channels in rat dorsal root ganglia J Physiol 1993 466 9-37 1175464 8410717
14. Cummins TR Dib-Hajj SD Black JA Akopian AN Wood JN Waxman SG A novel persistent tetrodotoxin-resistant sodium current in SNS-null and wild-type small primary sensory neurons J Neurosci 1999 19 RC43 10594087
15. Cummins TR Howe JR Waxman SG Slow closed-state inactivation: A novel mechanism underlying ramp currents in cells expressing the hNE/PN1 sodium channel J Neurosci 1998 18 9607-9619 9822722
16. Jeftinija S The role of tetrodotoxin-resistant sodium channels of small primary afferent fibers Brain Res 1994 639 125-134 10.1016/ 0006-8993(94)91772-8 8180828
17. Gaumann DM Brunet PC Jirounek P Clonidine enhances the effects of lidocaine on C-fiber action potential Anesth Analg 1992 74 719-725 10.1213/00000539-199205000-00017 1567041
18. Kobayashi J Ohta M Terada Y C fiber generates a slow Na+ spike in the frog sciatic nerve Neurosci Lett 1993 162 93-96 10.1016/ 0304-3940(93)90568-6 8121645
19. Leffler A Herzog RI Dib-Hajj SD Waxman SG Cummins TR Pharmacological properties of neuronal TTX-resistant sodium channels and the role of a critical serine pore residue Pflugers Arch 2005 15981012
20. Renganathan M Cummins TR Waxman SG Contribution of Na[v]1.8 sodium channels to action potential electrogenesis in DRG neurons J Neurophysiol 2001 86 629-640 11495938
21. Blair NT Bean BP Roles of tetrodotoxin [TTX]-sensitive Na+ current, TTX-resistant Na+ current, and Ca2+ current in the action potentials of nociceptive sensory neurons J Neurosci 2002 22 10277-10290 12451128
22. Matsutomi T Nakamoto C Zheng T Kakimura J Ogata N Multiple types of Na[+ currents mediate action potential electrogenesis in small neurons of mouse dorsal root ganglia Pflugers Arch 2006 453 83-96 10.1007/ s00424-006-0104-3 16838161
23. Novakovic SD Tzoumaka E McGivern JG Haraguchi M Sangameswaran L Gogas KR Eglen RM Hunter JC Distribution of the tetrodoxin-resistant sodium channel PN3 in rat sensory neurons in normal and neuropathic conditions J Neurosci 1998 18 2174-2187 9482802
24. Amaya F Decosterd I Samad TA Plumpton C Tate S Mannion RJ Costigan M Woolf CJ Diversity of expression of the sensory neuron-specific TTX-resistant voltage-gated sodium ion channels SNS and SNS2 Molec and Cell Neurosci 2000 15 331-342 10.1006/mcne.1999.0828
25. Scroggs RS Todorovic SM Anderson EG Fox AP Variation in IH, IIR, and ILEAK between acutely isolated adult rat dorsal root ganglion neurons of different size J Neurophysiol 1994 71 271-279 7512627
26. Tu H Deng L Sun Q Yao L Han JS Wan Y Hyperpolarization-activated, cyclic nucleotide-gated cation channels: Roles in the differential electrophysiological properties of rat primary afferent neurons J Neurosci Res 2004 76 713-22 10.1002/jnr.20109 15139030
27. Akopian AN Souslova V England S Okuse K Ogata N Ure J Smith A Kerr BJ McMahon SB Boyce S Hill R Stanfa LC Dickenson AH Wood JN The tetrodotoxin-resistant sodium channel SNS has a specialized function in pain pathways Nat Neurosci 1999 2 541-548 10.1038/9195 10448219
28. Herzog RI Cummins TR Waxman SG Persistent TTX-resistant Na+ current affects resting potential and response to depolarization in simulated spinal sensory neurons J Neurophysiol 2001 86 1351-1364 11535682
29. Herzog RI Cummins TR Ghassemi F Dib-Hajj SD Waxman SG Distinct repriming and closed-state inactivation kinetics of Nav1.6 and Nav1.7 sodium channels in mouse spinal sensory neurons J Physiol 2003 551 741-750 10.1113/jphysiol.2003.047357 12843211
30. Saab CY Cummins TR Waxman SG GTP gamma S increases Nav1.8 current in small-diameter dorsal root ganglia neurons Exp Brain Res 2003 152 415-419 10.1007/s00221-003-1565-7 12898089
31. Lee GY Shin YK Lee CS Song JH Effects of arachidonic acid on sodium currents in rat dorsal root ganglion neurons Brain Res 2002 950 95-102 10.1016/S0006-8993(02)03008-1 12231233
32. Ahern CA Zhang JF Wookalis MJ Horn R Modulation of the cardiac sodium channel Nav1.5 by Fyn, a Src family tyrosine kinase Circ Res 2005 96 991-998 10.1161/01.RES.0000166324.00524.dd 15831816
33. Hilborn MD Vaillancourt RR Rane SG Growth factor receptor tyrosine kinases acutely regulate neuronal sodium channels through the src signaling pathway J Neurosci 1998 18 590-600 9425001
34. Vijayaragavan R Powell AJ Kinghorn IJ Chahine M Role of auxiliary beta1-, beta2-, and beta3-subunits and their interaction with Na[v]1.8 voltage-gated sodium channel Biochem Biophys Res Commun 2004 319 2 531-540 10.1016/j.bbrc.2004.05.026 15178439
35. Rizzo MA Kocsis JD Waxman SG Slow sodium conductances of dorsal root ganglion neurons: Intraneuronal homogeneity and interneuronal heterogeneity J Neurophysiol 1994 72 2796-2815 7897490
36. Dib-Hajj SD Rush AM Cummins TR Hisama FM Novella S Tyrrell L Marshall L Waxman SG Gain-of-function mutation in Nav1.7 in familial erythromelalgia induces bursting of sensory neurons Brain 2005 128 1847-1854 10.1093/brain/awh514 15958509
37. Rush AM Dib-Hajj SD Liu S Cummins TR Black JA Waxman SG A single sodium channel mutation produces hyper- or hypoexcitability in different types of neurons Proc Natl Acad Sci USA 2006 1472458 16702558