High-efficiency nano- and micro-HPLC - high-resolution orbitrap-MS platform for top-down proteomics

Proteomics

Volumn 10, Issue 20, 2010, Pages 3598-3609

  Mohr, Jens ^a   Swart, Remco ^b   Samonig, Martin ^a   Böhm, Günter ^c   Huber, Christian G ^a  

^a UNIVERSITY OF SALZBURG   (Austria)

^b Dionex Benelux BV   (Netherlands)

^c Thermo Fisher Scientific   (United States)

Author keywords

HPLC; Monolithic columns; Orbitrap MS; Technology; Top down proteomics

Indexed keywords

ALCOHOL; BETA LACTOGLOBULIN; BOVINE SERUM ALBUMIN; CYTOCHROME C; HEMOGLOBIN A; HEMOGLOBIN BETA CHAIN; INSULIN; ION; LYSOZYME; MONOCLONAL ANTIBODY; MYOGLOBIN; OVALBUMIN; RECOMBINANT PROTEIN; RIBONUCLEASE A; VEGETABLE PROTEIN;

ARTICLE; GRAIN; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY ORBITRAP MASS SPECTROMETRY; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STRUCTURE; PROTEOMICS; ULTRAVIOLET RADIATION; WHEAT;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; LIMIT OF DETECTION; MOLECULAR WEIGHT; PROTEINS; PROTEOMICS; QUALITY CONTROL; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

TRITICUM AESTIVUM;

EID: 78649423856     PISSN: 16159853     EISSN: 16159861     Source Type: Journal    
DOI: 10.1002/pmic.201000341     Document Type: Article

References (45)

1. Aebersold, R., Mann, M., Mass spectrometry-based proteomics. Nature 2003, 422, 198-207.
2. Marko-Varga, G. (Ed.), Proteomics and Peptidomics. New Technology Platforms Elucidating Biology. Elsevier, Amsterdam 2005.
3. Cantin, G. T., Yates, J. R. I., Strategies for shotgun identification of post-translational modifications by mass spectrometry. J. Chromatogr. A 2004, 1053, 7-14.
4. Wu, S., Lourette, N. M., Tolic, N., Zhao, R. et al., An integrated top-down and bottom-up strategy for broadly characterizing protein isoforms and modifications. J. Proteome Res. 2009, 8, 1347-1357.
5. Whitelegge, J. P., Zabrouskov, V., Halgand, F., Souda, P. et al., Protein-sequence polymorphisms and post-translational modifications in proteins from human saliva using top-down Fourier-transform ion cyclotron resonance mass spectrometry. Int. J. Mass Spectrom. 2007, 268, 190-197.
6. Kelleher, N. L., Top-down proteomics. Anal. Chem. 2004, 76, 197A-203A.
7. Bogdanov, B., Smith, R. D., Proteomics by fticr mass spectrometry: top down and bottom up. Mass Spectrom. Rev. 2005, 24, 168-200.
8. Ferguson, J. T., Wenger, C. D., Metcalf, W. W., Kelleher, N. L., Top-down proteomics reveals novel protein forms expressed in Methanosarcina acetivorans. J. Am. Soc. Mass Spectrom. 2009, 20, 1743-1750.
9. Gygi, S. P., Corthals, G. L., Zhang, Y., Rochon, Y., Aebersold, R., Evaluation of two-dimensional gel electrophoresisbased proteome analysis technology. Proc. Natl. Acad. Sci. USA 2000, 97, 9390-9395.
10. Opiteck, G. J., Lewis, K. C., Jorgenson, J. W., Anderegg, R. J., Comprehensive on-line LC/LC/MS of proteins. Anal. Chem. 1997, 69, 1518-1524.
11. Lubman, D. M., Kachman, M. T., Wang, H., Gong, S. et al., Two-dimensional liquid separations-mass mapping of proteins from human cancer cell lysates. J. Chromatogr. B 2002, 782, 183-196.
12. Huber, C. G., Walcher, W., Timperio, A.-M., Troiani, S., Porceddu, E., Zolla, L., Multidimensional proteomic analysis of photosynthetic membrante proteins by liquid extractionultracentrifugation-liquid chromatography-mass spectrometry. Proteomics 2004, 4, 3909-3920.
13. Stephenson, J. L., Jr.,, McLuckey, S. A., Simplification of product ion spectra derived frommultiply charged parent ions via ion/ion chemistry. Anal. Chem. 1998, 70, 3533-3544.
14. Little, D. P., Speir, J. P., Senko, M. W., Oconnor, P. B., Mclafferty, F. W., Infrared multiphoton dissociation of large multiply-charged ions for biomolecule sequencing. Anal. Chem. 1994, 66, 2809-2815.
15. Cerda, B. A., Horn, D. M., Breuker, K., Carpenter, B. K., McLafferty, F. W., Electron capture dissociation of multiplycharged oxygenated cations. A nonergodic process. Eur. Mass Spectrom. 1999, 5, 335-338.
16. McAlister, G. C. P. D., Good, D. M., Berggren, W. T., Coon, J. J., Implementation of electron-transfer dissociation on a hybrid linear ion trap-orbitrap mass spectrometer. Anal. Chem. 2007, 79, 3525-3534.
17. Syka, J. E. P., Coon, J. J., Schroeder, M. J., Shabanowitz, J., Hunt, D. F., Peptide and protein sequence analysis by electron transfer dissociation mass spectrometry. Proc. Natl. Acad. Sci. USA 2004, 101, 9528-9533.
18. Jian Liu, P. A. C., Erickson, D. E., Scott, A., McLuckey, relative information content and top-down proteomics by mass spectrometry: Utility of ion/ion proton-transfer reactions in electrospray-based approaches. Anal. Chem. 2007, 79, 1073-1081.
19. McLafferty, F. W., Horn, D. M., Breuker, K., Ge, Y. et al., Electron capture dissociation of gaseous multiply charged ions by Fourier-transform ion cyclotron resonance. J. Am. Soc. Mass. Spectrom. 2001, 12, 245-249.
20. Hu, Q., Noll, R. J., Li, H., Makarov, A. et al., The orbitrap: a new mass spectrometer. J. Mass Spectrom. 2005, 40, 430-443.
21. Macek, B., Waanders, L. F., Olsen, J. V., Mann, M., Topdown protein sequencing and MS3 on a hybrid linear quadrupole ion trap-orbitrap mass spectrometer. Mol. Cell. Proteomics 2006, 5, 949-958.
22. Taylor, G. K., Kim, Y. B., Forbes, A. J., Meng, F. et al., Web and database software for identification of intact proteins using "Top down" mass spectrometry. Anal. Chem. 2003, 75, 4081-4086.
23. Zamdborg, L., LeDuc, R. D., Glowacz, K. J., Kim, Y. B. et al., Prosight ptm 2.0: improved protein identification and characterization for top down mass spectrometry. Nucleic Acids Res. 2007, 35, W701-W706.
24. Bondarenko, P. V., Second, T. P., Zabrouskov, V., Makarov, A. A., Zhang, Z., Mass measurement and top-down hplc/ms analysis of intact monoclonal antibodies on a hybrid linear quadrupole ion trap-orbitrap mass spectrometer. J. Am. Soc. Mass Spectrom. 2009, 20, 1415-1424.
25. Makarov, A., Denisov, E., Dynamics of ions of intact proteins in the orbitrap mass analyzer. J. Am. Soc. Mass Spectrom. 2009, 20, 1486-1495.
26. Zhang, Z., Shah, B., Characterization of variable regions of monoclonal antibodies by top-down mass spectrometry. Anal. Chem. 2007, 79, 5723-5729.
27. Makarov, A., Denisov, E., Kholomeev, A., Balschun, W. et al., Performance evaluation of a hybrid linear ion trap/orbitrap mass spectrometer. Anal. Chem. 2006, 78, 2113-2120.
28. Wu, S. L., Jardine, I., Hancock, W. S., Karger, B. L., A new and sensitive on-line liquid chromatography/mass spectrometric approach for top-down protein analysis: The comprehensive analysis of human growth hormone in an e. Coli lysate using a hybrid linear ion trap/Fourier transform ion cyclotron resonance mass spectrometer. Rapid Commun. Mass Spectrom. 2004, 18, 2201-2207.
29. Vellaichamy, A., Tran, J. C., Catherman, A. D., Lee, J. E. et al., Size-sorting combined with improved nanocapillary liquid chromatography-mass spectrometry for identification of intact proteins up to 80 kda. Anal. Chem. 2010, 82, 1234-1244.
30. Eschelbach, J. W., Jorgenson, J. W., Improved protein recovery in reversed-phase liquid chromatography by the use of ultrahigh pressures. Anal. Chem. 2006, 78, 1697-1706.
31. Premstaller, A., Oberacher, H., Walcher, W., Timperio, A.-M. et al., High-performance liquid chromatography-electrospray ionization mass spectrometry using monolithic capillary columns for proteomic studies. Anal. Chem. 2001, 73, 2390-2396.
32. Walcher, W., Oberacher, H., Troiani, S., Hö lzl, G. et al., Monolithic capillary columns for liquid chromatographyelectrospray ionization mass spectrometry in proteomic and genomic research. J. Chromatogr. B 2002, 782, 111-125.
33. Dullnig, V., Weiss, R., Amon, S., Rizzi, A., Stutz, H., Confirmation of immuno-reactivity of the recombinant major birch pollen allergen bet v 1a by affinity-cief. Electrophoresis 2009, 30, 2337-2346.
34. Premstaller, A., Oberacher, H., Huber, C. G., High-performance liquid chromatography-electrospray ionization mass spectrometry of single- and double stranded nucleic acids using monolithic capillary columns. Anal. Chem. 2000, 72, 4386-4393.
35. Schley, C., Swart, R., Huber, C. G., Capillary scale monolithic trap column for desalting and preconcentration of peptides and proteins in one- and twodimensional separations. J. Chromatogr. A 2006, 1136, 210-220.
36. Hsieh, S., Jorgenson, J. W., Preparation and evaluation of slurry-packed liquid chromatography microcolumns with inner diameters from 12 to 33 μm. Anal. Chem. 1996, 68, 1212-1217.
37. Pearson, J. D., Regnier, F. E., The influence of reversedphase n-alkyl chain length on protein retention, resolution, and recovery - implications for preparative hplc. J. Liq. Chromatogr. 1983, 6, 497-510.
38. Senko, M. W., Beu, S. C., Mclafferty, F. W., Determination of monoisotopic masses and ion populations for large biomolecules from resolved isotopic distributions. J. Am. Soc. Mass Spectrom. 1995, 6, 229-233.
39. Zhang, Z. Q., Marshall, A. G., A universal algorithm for fast and automated charge state deconvolution of electrospray mass-to-charge ratio spectra. J. Am. Soc. Mass. Spectrom. 1998, 9, 225-233.
40. Bar-Or, D., Bar-Or, R., Rael, L. T., Gardner, D. K. et al., Heterogeneity and oxidation status of commercial human albumin preparations in clinical use. Crit. Care Med. 2005, 33, 1638-1641.
41. Wada, Y., Tamura, J., Musselman, B. D., Kassel, D. B. et al., Electrospray ionization mass spectra of hemoglobin and transferrin by a magnetic sector mass spectrometer Comparison with theoretical isotopic distributions. Rapid Commun. Mass Spectrom. 1992, 6, 9-13.
42. Camafeita, E., Solis, J., Alfonso, P., Lopez, J. A. et al., Selective identification by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry of different types of gluten in foods made with cereal mixtures. J. Chromatogr. A 1998, 823, 299-306.
43. Mamone, G., Ferranti, P., Chianese, L., Scafuri, L., Addeo, F., Qualitative and quantitative analysis of wheat gluten proteins by liquid chromatography and electrospray mass spectrometry. Rapid Commun. Mass Spectrom. 2000, 14, 897-904.
44. Yang, F., Bogdanov, B., Strittmatter, E. F., Vilkov, A. N. et al., Characterization of purified c-type heme-containing peptides and identification of c-type heme-attachment sites in Shewanella oneidensis cytochromes using mass spectrometry. J. Proteome Res. 2005, 4, 846-854.
45. Ryan, C. M., Souda, P., Bassilian, S., Ujwal, R. et al., Posttranslational modifications of integral membrane proteins resolved by top-down Fourier transform mass spectrometry with collisionally activated dissociation. Mol. Cell. Proteomics 2010, 9, 791-803.