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Volumn 24, Issue 12, 2010, Pages 2292-2302

Mechanisms of progesterone receptor inhibition of inflammatory responses in cellular models of breast cancer

Author keywords

[No Author keywords available]

Indexed keywords

FACTOR AF2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; MIFEPRISTONE; ONAPRISTONE; PROGESTERONE RECEPTOR A; PROGESTERONE RECEPTOR B; PROMEGESTONE; TRANSCRIPTION FACTOR RELA;

EID: 78649397753     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2010-0289     Document Type: Article
Times cited : (33)

References (33)
  • 2
    • 0033082357 scopus 로고    scopus 로고
    • Onapristone, a progesterone receptor antagonist, as first-line therapy in primary breast cancer
    • DOI 10.1016/S0959-8049(98)00388-8, PII S0959804998003888
    • Robertson JF, Willsher PC, Winterbottom L, Blamey RW, Thorpe S 1999 Onapristone, a progesterone receptor antagonist, as first-line therapy in primary breast cancer. Eur J Cancer 35:214-218 (Pubitemid 29136770)
    • (1999) European Journal of Cancer , vol.35 , Issue.2 , pp. 214-218
    • Robertson, J.F.R.1    Willsher, P.C.2    Winterbottom, L.3    Blamey, R.W.4    Thorpe, S.5
  • 4
    • 0027299883 scopus 로고
    • Growth factor, steroid, and steroid antagonist regulation of cyclin gene expression associated with changes in T-47D human breast cancer cell cycle progression
    • Musgrove EA, Hamilton JA, Lee CS, Sweeney KJ, Watts CK, Sutherland RL 1993 Growth factor, steroid, and steroid antagonist regulation of cyclin gene expression associated with changes in T-47D human breast cancer cell cycle progression. Mol Cell Biol 13:3577-3587
    • (1993) Mol Cell Biol , vol.13 , pp. 3577-3587
    • Musgrove, E.A.1    Hamilton, J.A.2    Lee, C.S.3    Sweeney, K.J.4    Watts, C.K.5    Sutherland, R.L.6
  • 6
    • 35448981411 scopus 로고    scopus 로고
    • Progestin-dependent progression of human breast tumor xenografts: A novel model for evaluating antitumor therapeutics
    • Liang Y, Besch-Williford C, Brekken RA, Hyder SM 2007 Progestin-dependent progression of human breast tumor xenografts: a novel model for evaluating antitumor therapeutics. Cancer Res 67:9929-9936
    • (2007) Cancer Res , vol.67 , pp. 9929-9936
    • Liang, Y.1    Besch-Williford, C.2    Brekken, R.A.3    Hyder, S.M.4
  • 8
    • 0029939162 scopus 로고    scopus 로고
    • Negative interaction between the RelA(p65) subunit of NF-κB and the progesterone receptor
    • DOI 10.1074/jbc.271.11.6217
    • Kalkhoven E, Wissink S, van der Saag PT, van der Burg B 1996 Negative interaction between the RelA(p65) subunit of NF-κB and the progesterone receptor. J Biol Chem 271:6217-6224 (Pubitemid 26095429)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.11 , pp. 6217-6224
    • Kalkhoven, E.1    Wissink, S.2    Van Der Saag, P.T.3    Van Der Burg, B.4
  • 9
    • 33645406947 scopus 로고    scopus 로고
    • Up-regulation of the progesterone receptor (PR)-C isoform in laboring myometrium by activation of nuclear factor-κB may contribute to the onset of labor through inhibition of PR function
    • Condon JC, Hardy DB, Kovaric K, Mendelson CR 2006 Up-regulation of the progesterone receptor (PR)-C isoform in laboring myometrium by activation of nuclear factor-κB may contribute to the onset of labor through inhibition of PR function. Mol Endocrinol 20:764-775
    • (2006) Mol Endocrinol , vol.20 , pp. 764-775
    • Condon, J.C.1    Hardy, D.B.2    Kovaric, K.3    Mendelson, C.R.4
  • 10
    • 33751531210 scopus 로고    scopus 로고
    • Progesterone receptor plays a major antiinflammatory role in human myometrial cells by antagonism of nuclear factor-κB activation of cyclooxygenase 2 expression
    • Hardy DB, Janowski BA, Corey DR, Mendelson CR 2006 Progesterone receptor plays a major antiinflammatory role in human myometrial cells by antagonism of nuclear factor-κB activation of cyclooxygenase 2 expression. Mol Endocrinol 20:2724-2733
    • (2006) Mol Endocrinol , vol.20 , pp. 2724-2733
    • Hardy, D.B.1    Janowski, B.A.2    Corey, D.R.3    Mendelson, C.R.4
  • 11
    • 48249132500 scopus 로고    scopus 로고
    • Progesterone receptor inhibits aromatase and inflammatory response pathways in breast cancer cells via ligand-dependent and ligand-independent mechanisms
    • Hardy DB, Janowski BA, Chen CC, Mendelson CR 2008 Progesterone receptor inhibits aromatase and inflammatory response pathways in breast cancer cells via ligand-dependent and ligand-independent mechanisms. Mol Endocrinol 22:1812-1824
    • (2008) Mol Endocrinol , vol.22 , pp. 1812-1824
    • Hardy, D.B.1    Janowski, B.A.2    Chen, C.C.3    Mendelson, C.R.4
  • 12
    • 1542644825 scopus 로고    scopus 로고
    • NF-κB in Mammary Gland Development and Breast Cancer
    • DOI 10.1023/A:1025905008934, Transcription Factors in Mammary Gland Biology and Neoplasia
    • Cao Y, Karin M 2003 NF-κB in mammary gland development and breast cancer. J Mammary Gland Biol Neoplasia 8:215-223 (Pubitemid 38129943)
    • (2003) Journal of Mammary Gland Biology and Neoplasia , vol.8 , Issue.2 , pp. 215-223
    • Cao, Y.1    Karin, M.2
  • 13
    • 0028867899 scopus 로고
    • Immunosuppression by glucocorticoids: Inhibition of NF-κB activity through induction of IκB synthesis
    • Auphan N, DiDonato JA, Rosette C, Helmberg A, Karin M 1995 Immunosuppression by glucocorticoids: inhibition of NF-κB activity through induction of IκB synthesis. Science 270:286-290
    • (1995) Science , vol.270 , pp. 286-290
    • Auphan, N.1    DiDonato, J.A.2    Rosette, C.3    Helmberg, A.4    Karin, M.5
  • 16
    • 34447331410 scopus 로고    scopus 로고
    • Dexamethasone suppresses monocyte chemoattractant protein-1 production via mitogen activated protein kinase phosphatase-1 dependent inhibition of Jun N-terminal kinase and p38 mitogen-activated protein kinase in activated rat microglia
    • Zhou Y, Ling EA, Dheen ST 2007 Dexamethasone suppresses monocyte chemoattractant protein-1 production via mitogen activated protein kinase phosphatase-1 dependent inhibition of Jun N-terminal kinase and p38 mitogen-activated protein kinase in activated rat microglia. J Neurochem 102:667-678
    • (2007) J Neurochem , vol.102 , pp. 667-678
    • Zhou, Y.1    Ling, E.A.2    Dheen, S.T.3
  • 18
    • 0035861855 scopus 로고    scopus 로고
    • Human macrophage inflammatory protein-3α/CCL20/LARC/Exodus/SCYA20 is transcriptionally upregulated by tumor necrosis factor-α via a non-standard NF-κB site
    • Harant H, Eldershaw SA, Lindley IJ 2001 Human macrophage inflammatory protein-3α/CCL20/LARC/Exodus/SCYA20 is transcriptionally upregulated by tumor necrosis factor-α via a non-standard NF-κB site. FEBS Lett 509:439-445
    • (2001) FEBS Lett , vol.509 , pp. 439-445
    • Harant, H.1    Eldershaw, S.A.2    Lindley, I.J.3
  • 19
    • 0034665748 scopus 로고    scopus 로고
    • The glucocorticoid receptor inhibits NFκB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain
    • Nissen RM, Yamamoto KR 2000 The glucocorticoid receptor inhibits NFκB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain. Genes Dev 14:2314-2329
    • (2000) Genes Dev , vol.14 , pp. 2314-2329
    • Nissen, R.M.1    Yamamoto, K.R.2
  • 20
    • 0033513582 scopus 로고    scopus 로고
    • Dissection of the LXXLL nuclear receptor-coactivator interaction motif using combinatorial peptide libraries: Discovery of peptide antagonists of estrogen receptors α and β
    • Chang C, Norris JD, Grøn H, Paige LA, Hamilton PT, Kenan DJ, Fowlkes D, McDonnell DP 1999 Dissection of the LXXLL nuclear receptor-coactivator interaction motif using combinatorial peptide libraries: discovery of peptide antagonists of estrogen receptors α and β. Mol Cell Biol 19:8226-8239
    • (1999) Mol Cell Biol , vol.19 , pp. 8226-8239
    • Chang, C.1    Norris, J.D.2    Grøn, H.3    Paige, L.A.4    Hamilton, P.T.5    Kenan, D.J.6    Fowlkes, D.7    McDonnell, D.P.8
  • 21
    • 0030986236 scopus 로고    scopus 로고
    • A signature motif in transcriptional co-activators mediates binding to nuclear receptors
    • DOI 10.1038/42750
    • Heery DM, Kalkhoven E, Hoare S, Parker MG 1997 A signature motif in transcriptional co-activators mediates binding to nuclear receptors. Nature 387:733-736 (Pubitemid 27270617)
    • (1997) Nature , vol.387 , Issue.6634 , pp. 733-736
    • Heery, D.M.1    Kalkhoven, E.2    Hoare, S.3    Parker, M.G.4
  • 22
    • 0035794168 scopus 로고    scopus 로고
    • Core LXXLL motif sequences in CREB-binding protein, SRC1, and RIP140 define affinity and selectivity for steroid and retinoid receptors
    • Heery DM, Hoare S, Hussain S, Parker MG, Sheppard H 2001 Core LXXLL motif sequences in CREB-binding protein, SRC1, and RIP140 define affinity and selectivity for steroid and retinoid receptors. J Biol Chem 276:6695-6702
    • (2001) J Biol Chem , vol.276 , pp. 6695-6702
    • Heery, D.M.1    Hoare, S.2    Hussain, S.3    Parker, M.G.4    Sheppard, H.5
  • 25
    • 18244381020 scopus 로고    scopus 로고
    • The glucocorticoid receptor blocks P-TEFb recruitment by NFκB to effect promoter-specific transcriptional repression
    • Luecke HF, Yamamoto KR 2005 The glucocorticoid receptor blocks P-TEFb recruitment by NFκB to effect promoter-specific transcriptional repression. Genes Dev 19:1116-1127
    • (2005) Genes Dev , vol.19 , pp. 1116-1127
    • Luecke, H.F.1    Yamamoto, K.R.2
  • 26
    • 44549088535 scopus 로고    scopus 로고
    • Challenges to defining a role for progesterone in breast cancer
    • Lange CA 2008 Challenges to defining a role for progesterone in breast cancer. Steroids 73:914-921
    • (2008) Steroids , vol.73 , pp. 914-921
    • Lange, C.A.1
  • 27
    • 0034597740 scopus 로고    scopus 로고
    • Progestin effects on long-term growth, death, and Bcl-xL in breast cancer cells
    • Moore MR, Conover JL, Franks KM 2000 Progestin effects on long-term growth, death, and Bcl-xL in breast cancer cells. Biochem Biophys Res Commun 277:650-654
    • (2000) Biochem Biophys Res Commun , vol.277 , pp. 650-654
    • Moore, M.R.1    Conover, J.L.2    Franks, K.M.3
  • 28
    • 33846581488 scopus 로고    scopus 로고
    • The role of extranuclear signaling actions of progesterone receptor in mediating progesterone regulation of gene expression and the cell cycle
    • Boonyaratanakornkit V, McGowan E, Sherman L, Mancini MA, Cheskis BJ, Edwards DP 2007 The role of extranuclear signaling actions of progesterone receptor in mediating progesterone regulation of gene expression and the cell cycle. Mol Endocrinol 21:359-375
    • (2007) Mol Endocrinol , vol.21 , pp. 359-375
    • Boonyaratanakornkit, V.1    McGowan, E.2    Sherman, L.3    Mancini, M.A.4    Cheskis, B.J.5    Edwards, D.P.6
  • 29
    • 11144337833 scopus 로고    scopus 로고
    • Quantitative real-time PCR protocol for analysis of nuclear receptor signaling pathways
    • Bookout AL, Mangelsdorf DJ 2003 Quantitative real-time PCR protocol for analysis of nuclear receptor signaling pathways. Nucl Recept Signal 1:e012
    • (2003) Nucl Recept Signal , vol.1
    • Bookout, A.L.1    Mangelsdorf, D.J.2
  • 30
    • 35148869577 scopus 로고    scopus 로고
    • Definition of functionally important mechanistic differences among selective estrogen receptor down-regulators
    • Wittmann BM, Sherk A, McDonnell DP 2007 Definition of functionally important mechanistic differences among selective estrogen receptor down-regulators. Cancer Res 67:9549-9560
    • (2007) Cancer Res , vol.67 , pp. 9549-9560
    • Wittmann, B.M.1    Sherk, A.2    McDonnell, D.P.3
  • 31
    • 0034463134 scopus 로고    scopus 로고
    • Differential hormone-dependent phosphorylation of progesterone receptor a and B forms revealed by a phosphoserine site-specific monoclonal antibody
    • DOI 10.1210/me.14.1.52
    • Clemm DL, Sherman L, Boonyaratanakornkit V, Schrader WT, Weigel NL, Edwards DP 2000 Differential hormone-dependent phosphorylation of progesterone receptor A and B forms revealed by a phosphoserine site-specific monoclonal antibody. Mol Endocrinol 14:52-65 (Pubitemid 32260327)
    • (2000) Molecular Endocrinology , vol.14 , Issue.1 , pp. 52-65
    • Clemm, D.L.1    Sherman, L.2    Boonyaratanakornkit, V.3    Schrader, W.T.4    Weigel, N.L.5    Edwards, D.P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.