메뉴 건너뛰기




Volumn 5, Issue 6, 2010, Pages 891-900

An efficient method for generation of neural-like cells from adult human bone marrow-derived mesenchymal stem cells

Author keywords

epigenetics; glial; mesenchymal stem cell; neural stem cell; neuronal; transdifferentiation

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CELL MARKER; CYCLIC AMP; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; HISTONE;

EID: 78649352249     PISSN: 17460751     EISSN: None     Source Type: Journal    
DOI: 10.2217/rme.10.67     Document Type: Article
Times cited : (31)

References (67)
  • 1
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fbroblast cultures by defned factors
    • Takahashi K, Yamanaka S: Induction of pluripotent stem cells from mouse embryonic and adult fbroblast cultures by defned factors. Cell 126(4), 663-676 (2006).
    • (2006) Cell , vol.126 , Issue.4 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 2
    • 66049143859 scopus 로고    scopus 로고
    • Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins
    • Kim D, Kim CH, Moon JI et al.: Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins. Cell Stem Cell 4(6), 472-476 (2009).
    • (2009) Cell Stem Cell , vol.4 , Issue.6 , pp. 472-476
    • Kim, D.1    Kim, C.H.2    Moon, J.I.3
  • 3
    • 77649159797 scopus 로고    scopus 로고
    • Generation of induced pluripotent stem (iPS) cells by effcient reprogramming of adult bone marrow cells
    • Kunisato A, Wakatsuki M, Kodama Y et al.: Generation of induced pluripotent stem (iPS) cells by effcient reprogramming of adult bone marrow cells. Stem Cells Dev. 19(2), 229-238 (2009).
    • (2009) Stem Cells Dev. , vol.19 , Issue.2 , pp. 229-238
    • Kunisato, A.1    Wakatsuki, M.2    Kodama, Y.3
  • 4
    • 68549107942 scopus 로고    scopus 로고
    • Generation and characterization of human induced pluripotent stem cells
    • Unit 4A.2
    • Ohnuki M, Takahashi K, Yamanaka S: Generation and characterization of human induced pluripotent stem cells. Curr. Protoc. Stem Cell Biol. 4, Unit 4A.2 (2009).
    • (2009) Curr. Protoc. Stem Cell Biol. , vol.4
    • Ohnuki, M.1    Takahashi, K.2    Yamanaka, S.3
  • 5
    • 35448949103 scopus 로고    scopus 로고
    • Inhibition of histone deacetylase activity induces developmental plasticity in oligodendrocyte precursor cells
    • Lyssiotis CA, Walker J, Wu C et al.: Inhibition of histone deacetylase activity induces developmental plasticity in oligodendrocyte precursor cells. Proc. Natl Acad. Sci. USA 104(38), 14982-14987 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , Issue.38 , pp. 14982-14987
    • Lyssiotis, C.A.1    Walker, J.2    Wu, C.3
  • 6
    • 0030889354 scopus 로고    scopus 로고
    • Marrow stromal cells as stem cells for nonhematopoietic tissues
    • Prockop DJ: Marrow stromal cells as stem cells for nonhematopoietic tissues. Science 276(5309), 71-74 (1997).
    • (1997) Science , vol.276 , Issue.5309 , pp. 71-74
    • Prockop, D.J.1
  • 8
    • 0034605069 scopus 로고    scopus 로고
    • Clonal isolation of muscle-derived cells capable of enhancing muscle regeneration and bone healing
    • Lee JY, Qu-Petersen Z, Cao B et al.: Clonal isolation of muscle-derived cells capable of enhancing muscle regeneration and bone healing. J. Cell Biol. 150(5), 1085-1100 (2000).
    • (2000) J. Cell Biol. , vol.150 , Issue.5 , pp. 1085-1100
    • Lee, J.Y.1    Qu-Petersen, Z.2    Cao, B.3
  • 9
    • 0026501993 scopus 로고
    • The pericyte as a possible osteoblast progenitor cell
    • Brighton CT, Lorich DG, Kupcha R et al.: The pericyte as a possible osteoblast progenitor cell. Clin. Orthop. (275), 287-299 (1992).
    • (1992) Clin. Orthop. , vol.275 , pp. 287-299
    • Brighton, C.T.1    Lorich, D.G.2    Kupcha, R.3
  • 10
    • 0030601329 scopus 로고    scopus 로고
    • Chondroinduction of human dermal fbroblasts by demineralized bone in three-dimensional culture
    • Mizuno S, Glowacki J: Chondroinduction of human dermal fbroblasts by demineralized bone in three-dimensional culture. Exp. Cell Res. 227(1), 89-97 (1996).
    • (1996) Exp. Cell Res. , vol.227 , Issue.1 , pp. 89-97
    • Mizuno, S.1    Glowacki, J.2
  • 11
    • 0035067539 scopus 로고    scopus 로고
    • Multilineage cells from human adipose tissue: Implications for cell-based therapies
    • Zuk PA, Zhu M, Mizuno H et al.: Multilineage cells from human adipose tissue: implications for cell-based therapies. Tissue Eng. 7(2), 211-228 (2001).
    • (2001) Tissue Eng. , vol.7 , Issue.2 , pp. 211-228
    • Zuk, P.A.1    Zhu, M.2    Mizuno, H.3
  • 12
    • 1442356953 scopus 로고    scopus 로고
    • Isolation of multipotent mesenchymal stem cells from umbilical cord blood
    • Lee OK, Kuo TK, Chen WM et al.: Isolation of multipotent mesenchymal stem cells from umbilical cord blood. Blood 103(5), 1669-1675 (2004).
    • (2004) Blood , vol.103 , Issue.5 , pp. 1669-1675
    • Lee, O.K.1    Kuo, T.K.2    Chen, W.M.3
  • 13
    • 0029000896 scopus 로고
    • Cultured adherent cells from marrow can serve as long-lasting precursor cells for bone, cartilage, and lung in irradiated mice
    • Pereira RF, Halford KW, O'Hara MD et al.: Cultured adherent cells from marrow can serve as long-lasting precursor cells for bone, cartilage, and lung in irradiated mice. Proc. Natl Acad. Sci. USA 92(11), 4857-4861 (1995).
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , Issue.11 , pp. 4857-4861
    • Pereira, R.F.1    Halford, K.W.2    O'Hara, M.D.3
  • 14
    • 0032477883 scopus 로고    scopus 로고
    • Marrow stromal cells as a source of progenitor cells for nonhematopoietic tissues in transgenic mice with a phenotype of osteogenesis imperfecta
    • Pereira RF, O'Hara MD, Laptev AV et al.: Marrow stromal cells as a source of progenitor cells for nonhematopoietic tissues in transgenic mice with a phenotype of osteogenesis imperfecta. Proc. Natl Acad. Sci. USA 95(3), 1142-1147 (1998).
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , Issue.3 , pp. 1142-1147
    • Pereira, R.F.1    O'Hara, M.D.2    Laptev, A.V.3
  • 15
    • 0025965055 scopus 로고
    • Colony-stimulating factor 1 expression is down-regulated during the adipocyte differentiation of H-1/A marrow stromal cells and induced by cachectin/tumor necrosis factor
    • Umezawa A, Tachibana K, Harigaya K et al.: Colony-stimulating factor 1 expression is down-regulated during the adipocyte differentiation of H-1/A marrow stromal cells and induced by cachectin/tumor necrosis factor. Mol. Cell Biol. 11(2), 920-927 (1991).
    • (1991) Mol. Cell Biol. , vol.11 , Issue.2 , pp. 920-927
    • Umezawa, A.1    Tachibana, K.2    Harigaya, K.3
  • 16
    • 0032489651 scopus 로고    scopus 로고
    • Muscle regeneration by bone marrow-derived myogenic progenitors
    • Ferrari G, Cusella-De Angelis G, Coletta M et al.: Muscle regeneration by bone marrow-derived myogenic progenitors. Science 279(5356), 1528-1530 (1998).
    • (1998) Science , vol.279 , Issue.5356 , pp. 1528-1530
    • Ferrari, G.1    Cusella-De Angelis, G.2    Coletta, M.3
  • 17
    • 0033106384 scopus 로고    scopus 로고
    • Cardiomyocytes can be generated from marrow stromal cells in vitro
    • Makino S, Fukuda K, Miyoshi S et al.: Cardiomyocytes can be generated from marrow stromal cells in vitro. J. Clin. Invest. 103(5), 697-705 (1999).
    • (1999) J. Clin. Invest. , vol.103 , Issue.5 , pp. 697-705
    • Makino, S.1    Fukuda, K.2    Miyoshi, S.3
  • 18
    • 0035495740 scopus 로고    scopus 로고
    • Brain from bone: Effcient 'meta-differentiation' of marrow stroma-derived mature osteoblasts to neurons with Noggin or a demethylating agent
    • Kohyama J, Abe H, Shimazaki T et al.: Brain from bone: effcient 'meta-differentiation' of marrow stroma-derived mature osteoblasts to neurons with Noggin or a demethylating agent. Differentiation 68(4-5), 235-244 (2001).
    • (2001) Differentiation , vol.68 , Issue.4-5 , pp. 235-244
    • Kohyama, J.1    Abe, H.2    Shimazaki, T.3
  • 19
    • 0032584132 scopus 로고    scopus 로고
    • Engraftment and migration of human bone marrow stromal cells implanted in the brains of albino rats-similarities to astrocyte grafts
    • Azizi SA, Stokes D, Augelli BJ, DiGirolamo C, Prockop DJ: Engraftment and migration of human bone marrow stromal cells implanted in the brains of albino rats-similarities to astrocyte grafts. Proc. Natl Acad. Sci. USA 95(7), 3908-3913 (1998).
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , Issue.7 , pp. 3908-3913
    • Azizi, S.A.1    Stokes, D.2    Augelli, B.J.3    Digirolamo, C.4    Prockop, D.J.5
  • 20
    • 0032874061 scopus 로고    scopus 로고
    • Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains
    • Kopen GC, Prockop DJ, Phinney DG: Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains. Proc. Natl Acad. Sci. USA 96(19), 10711-10716 (1999).
    • (1999) Proc. Natl Acad. Sci. USA , vol.96 , Issue.19 , pp. 10711-10716
    • Kopen, G.C.1    Prockop, D.J.2    Phinney, D.G.3
  • 21
    • 2442666643 scopus 로고    scopus 로고
    • Adult bone marrow stromal cells in the embryonic brain: Engraftment, migration, differentiation, and long-term survival
    • Munoz-Elias G, Marcus AJ, Coyne TM, Woodbury D, Black IB: Adult bone marrow stromal cells in the embryonic brain: engraftment, migration, differentiation, and long-term survival. J. Neurosci. 24(19), 4585-4595 (2004).
    • (2004) J. Neurosci. , vol.24 , Issue.19 , pp. 4585-4595
    • Munoz-Elias, G.1    Marcus, A.J.2    Coyne, T.M.3    Woodbury, D.4    Black, I.B.5
  • 22
    • 24044528210 scopus 로고    scopus 로고
    • CAMP induces neuronal differentiation of mesenchymal stem cells via activation of extracellular signal-regulated kinase/MAPK
    • Kim SS, Choi JM, Kim JW et al.: cAMP induces neuronal differentiation of mesenchymal stem cells via activation of extracellular signal-regulated kinase/MAPK. Neuroreport 16(12), 1357-1361 (2005).
    • (2005) Neuroreport , vol.16 , Issue.12 , pp. 1357-1361
    • Kim, S.S.1    Choi, J.M.2    Kim, J.W.3
  • 23
    • 0034537437 scopus 로고    scopus 로고
    • Adult bone marrow stromal cells differentiate into neural cells in vitro
    • Sanchez-Ramos J, Song S, Cardozo-Pelaez F et al.: Adult bone marrow stromal cells differentiate into neural cells in vitro. Exp. Neurol. 164(2), 247-256 (2000).
    • (2000) Exp. Neurol. , vol.164 , Issue.2 , pp. 247-256
    • Sanchez-Ramos, J.1    Song, S.2    Cardozo-Pelaez, F.3
  • 24
    • 0037007985 scopus 로고    scopus 로고
    • Differentiation of adult bone marrow stem cells into neuroprogenitor cells in vitro
    • Kim BJ, Seo JH, Bubien JK, Oh YS: Differentiation of adult bone marrow stem cells into neuroprogenitor cells in vitro. Neuroreport 13(9), 1185-1188 (2002).
    • (2002) Neuroreport , vol.13 , Issue.9 , pp. 1185-1188
    • Kim, B.J.1    Seo, J.H.2    Bubien, J.K.3    Oh, Y.S.4
  • 25
    • 0346502992 scopus 로고    scopus 로고
    • Postnatal astrocytes promote neural induction from adult human bone marrow-derived stem cells
    • Joannides A, Gaughwin P, Scott M et al.: Postnatal astrocytes promote neural induction from adult human bone marrow-derived stem cells. J. Hematother. Stem Cell Res. 12(6), 681-688 (2003).
    • (2003) J. Hematother. Stem Cell Res. , vol.12 , Issue.6 , pp. 681-688
    • Joannides, A.1    Gaughwin, P.2    Scott, M.3
  • 27
    • 16344379018 scopus 로고    scopus 로고
    • Sonic hedgehog and retinoic acid synergistically promote sensory fate specifcation from bone marrow-derived pluripotent stem cells
    • Kondo T, Johnson SA, Yoder MC, Romand R, Hashino E: Sonic hedgehog and retinoic acid synergistically promote sensory fate specifcation from bone marrow-derived pluripotent stem cells. Proc. Natl Acad. Sci. USA 102(13), 4789-4794 (2005).
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , Issue.13 , pp. 4789-4794
    • Kondo, T.1    Johnson, S.A.2    Yoder, M.C.3    Romand, R.4    Hashino, E.5
  • 28
    • 21244477905 scopus 로고    scopus 로고
    • Protective effects of bone marrow stromal cell transplantation in injured rodent brain: Synthesis of neurotrophic factors
    • Chen Q, Long Y, Yuan X et al.: Protective effects of bone marrow stromal cell transplantation in injured rodent brain: synthesis of neurotrophic factors. J. Neurosci. Res. 80(5), 611-619 (2005).
    • (2005) J. Neurosci. Res. , vol.80 , Issue.5 , pp. 611-619
    • Chen, Q.1    Long, Y.2    Yuan, X.3
  • 29
    • 14744272963 scopus 로고    scopus 로고
    • Neural cell differentiation in vitro from adult human bone marrow mesenchymal stem cells
    • Long X, Olszewski M, Huang W, Kletzel M: Neural cell differentiation in vitro from adult human bone marrow mesenchymal stem cells. Stem Cells Dev. 14(1), 65-69 (2005).
    • (2005) Stem Cells Dev. , vol.14 , Issue.1 , pp. 65-69
    • Long, X.1    Olszewski, M.2    Huang, W.3    Kletzel, M.4
  • 30
    • 3042798843 scopus 로고    scopus 로고
    • Induction of bone marrow stromal cells to neurons: Differentiation, transdifferentiation, or artifact?
    • Lu P, Blesch A, Tuszynski MH: Induction of bone marrow stromal cells to neurons: differentiation, transdifferentiation, or artifact? J. Neurosci. Res. 77(2), 174-191 (2004).
    • (2004) J. Neurosci. Res. , vol.77 , Issue.2 , pp. 174-191
    • Lu, P.1    Blesch, A.2    Tuszynski, M.H.3
  • 31
    • 20944437813 scopus 로고    scopus 로고
    • Human mesenchymal stem cells differentiate into neuron-like cells and show SMN protein expression
    • Yang XS, Wu HX, Xiao B: [Human mesenchymal stem cells differentiate into neuron-like cells and show SMN protein expression]. Zhonghua Yi Xue Za Zhi 85(16), 1125-1128 (2005).
    • (2005) Zhonghua Yi Xue Za Zhi , vol.85 , Issue.16 , pp. 1125-1128
    • Yang, X.S.1    Wu, H.X.2    Xiao, B.3
  • 32
    • 0038787488 scopus 로고    scopus 로고
    • Marrow stromal cells, mitosis, and neuronal differentiation: Stem cell and precursor functions
    • Munoz-Elias G, Woodbury D, Black IB: Marrow stromal cells, mitosis, and neuronal differentiation: stem cell and precursor functions. Stem Cells 21(4), 437-448 (2003).
    • (2003) Stem Cells , vol.21 , Issue.4 , pp. 437-448
    • Munoz-Elias, G.1    Woodbury, D.2    Black, I.B.3
  • 33
    • 0034809239 scopus 로고    scopus 로고
    • In vitro differentiation of human marrow stromal cells into early progenitors of neural cells by conditions that increase intracellular cyclic AMP
    • Deng W, Obrocka M, Fischer I, Prockop DJ: In vitro differentiation of human marrow stromal cells into early progenitors of neural cells by conditions that increase intracellular cyclic AMP. Biochem. Biophys. Res. Commun. 282(1), 148-152 (2001).
    • (2001) Biochem. Biophys. Res. Commun. , vol.282 , Issue.1 , pp. 148-152
    • Deng, W.1    Obrocka, M.2    Fischer, I.3    Prockop, D.J.4
  • 34
    • 33744914853 scopus 로고    scopus 로고
    • Comparative ana lysis of neuroectodermal differentiation capacity of human bone marrow stromal cells using various conversion protocols
    • Hermann A, Liebau S, Gastl R et al.: Comparative ana lysis of neuroectodermal differentiation capacity of human bone marrow stromal cells using various conversion protocols. J. Neurosci. Res. 83(8), 1502-1514 (2006)
    • (2006) J. Neurosci. Res. , vol.83 , Issue.8 , pp. 1502-1514
    • Hermann, A.1    Liebau, S.2    Gastl, R.3
  • 35
    • 21744446893 scopus 로고    scopus 로고
    • SOX2 functions in adult neural stem cells
    • Episkopou V: SOX2 functions in adult neural stem cells. Trends Neurosci. 28(5), 219-221 (2005).
    • (2005) Trends Neurosci. , vol.28 , Issue.5 , pp. 219-221
    • Episkopou, V.1
  • 36
    • 5044220530 scopus 로고    scopus 로고
    • Bone marrow transplants provide tissue protection and directional guidance for axons after contusive spinal cord injury in rats
    • Ankeny DP, McTigue DM, Jakeman LB: Bone marrow transplants provide tissue protection and directional guidance for axons after contusive spinal cord injury in rats. Exp. Neurol. 190(1), 17-31 (2004).
    • (2004) Exp. Neurol. , vol.190 , Issue.1 , pp. 17-31
    • Ankeny, D.P.1    McTigue, D.M.2    Jakeman, L.B.3
  • 37
    • 21744460838 scopus 로고    scopus 로고
    • Molecular pathways involved in neural in vitro differentiation of marrow stromal stem cells
    • Jori FP, Napolitano MA, Melone MA et al.: Molecular pathways involved in neural in vitro differentiation of marrow stromal stem cells. J. Cell Biochem. 94(4), 645-655 (2005).
    • (2005) J. Cell Biochem. , vol.94 , Issue.4 , pp. 645-655
    • Jori, F.P.1    Napolitano, M.A.2    Melone, M.A.3
  • 38
    • 3042769428 scopus 로고    scopus 로고
    • Specifc induction of neuronal cells from bone marrow stromal cells and application for autologous transplantation
    • Dezawa M, Kanno H, Hoshino M et al.: Specifc induction of neuronal cells from bone marrow stromal cells and application for autologous transplantation. J. Clin. Invest. 113(12), 1701-1710 (2004).
    • (2004) J. Clin. Invest. , vol.113 , Issue.12 , pp. 1701-1710
    • Dezawa, M.1    Kanno, H.2    Hoshino, M.3
  • 39
    • 0344825241 scopus 로고    scopus 로고
    • Improving the expansion and neuronal differentiation of mesenchymal stem cells through culture surface modifcation
    • Qian L, Saltzman WM: Improving the expansion and neuronal differentiation of mesenchymal stem cells through culture surface modifcation. Biomaterials 25(7-8), 1331-1337 (2004).
    • (2004) Biomaterials , vol.25 , Issue.7-8 , pp. 1331-1337
    • Qian, L.1    Saltzman, W.M.2
  • 40
    • 0141817748 scopus 로고    scopus 로고
    • Neuroectodermal differentiation from mouse multipotent adult progenitor cells
    • Jiang Y, Henderson D, Blackstad M et al.: Neuroectodermal differentiation from mouse multipotent adult progenitor cells. Proc. Natl Acad. Sci. USA 100(Suppl. 1), 11854-11860 (2003).
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , Issue.SUPPL. 1 , pp. 11854-11860
    • Jiang, Y.1    Henderson, D.2    Blackstad, M.3
  • 41
    • 15544376664 scopus 로고    scopus 로고
    • Plasticity of cultured mesenchymal stem cells: Switch from nestin-positive to excitable neuron-like phenotype
    • Wislet-Gendebien S, Hans G, Leprince P et al.: Plasticity of cultured mesenchymal stem cells: switch from nestin-positive to excitable neuron-like phenotype. Stem Cells 23(3), 392-402 (2005).
    • (2005) Stem Cells , vol.23 , Issue.3 , pp. 392-402
    • Wislet-Gendebien, S.1    Hans, G.2    Leprince, P.3
  • 42
    • 26844431677 scopus 로고    scopus 로고
    • Neural stem cells induce bone-marrow-derived mesenchymal stem cells to generate neural stem-like cells via juxtacrine and paracrine interactions
    • Alexanian AR: Neural stem cells induce bone-marrow-derived mesenchymal stem cells to generate neural stem-like cells via juxtacrine and paracrine interactions. Exp. Cell Res. 310(2), 383-391 (2005).
    • (2005) Exp. Cell Res. , vol.310 , Issue.2 , pp. 383-391
    • Alexanian, A.R.1
  • 43
    • 33846013213 scopus 로고    scopus 로고
    • Induction of neural-like differentiation in human mesenchymal stem cells derived from bone marrow, fat, spleen and thymus
    • Krampera M, Marconi S, Pasini A et al.: Induction of neural-like differentiation in human mesenchymal stem cells derived from bone marrow, fat, spleen and thymus. Bone 40(2), 382-390 (2007).
    • (2007) Bone , vol.40 , Issue.2 , pp. 382-390
    • Krampera, M.1    Marconi, S.2    Pasini, A.3
  • 44
    • 33847066751 scopus 로고    scopus 로고
    • Isolation and characterization of bone marrow-derived mesenchymal progenitor cells with myogenic and neuronal properties
    • Shiota M, Heike T, Haruyama M et al.: Isolation and characterization of bone marrow-derived mesenchymal progenitor cells with myogenic and neuronal properties. Exp. Cell Res. 313(5), 1008-1023 (2007).
    • (2007) Exp. Cell Res. , vol.313 , Issue.5 , pp. 1008-1023
    • Shiota, M.1    Heike, T.2    Haruyama, M.3
  • 45
    • 17244373506 scopus 로고    scopus 로고
    • Bromodeoxyuridine increases multipotency of human bone marrow-derived stem cells
    • Qu TY, Dong XJ, Sugaya I et al.: Bromodeoxyuridine increases multipotency of human bone marrow-derived stem cells. Restor. Neurol. Neurosci. 22(6), 459-468 (2004).
    • (2004) Restor. Neurol. Neurosci. , vol.22 , Issue.6 , pp. 459-468
    • Qu, T.Y.1    Dong, X.J.2    Sugaya, I.3
  • 46
    • 0037041427 scopus 로고    scopus 로고
    • Bone marrow cells adopt the phenotype of other cells by spontaneous cell fusion
    • Terada N, Hamazaki T, Oka M et al.: Bone marrow cells adopt the phenotype of other cells by spontaneous cell fusion. Nature 416(6880), 542-545 (2002).
    • (2002) Nature , vol.416 , Issue.6880 , pp. 542-545
    • Terada, N.1    Hamazaki, T.2    Oka, M.3
  • 47
    • 3042801100 scopus 로고    scopus 로고
    • Reevaluation of in vitro differentiation protocols for bone marrow stromal cells: Disruption of actin cytoskeleton induces rapid morphological changes and mimics neuronal phenotype
    • Neuhuber B, Gallo G, Howard L et al.: Reevaluation of in vitro differentiation protocols for bone marrow stromal cells: disruption of actin cytoskeleton induces rapid morphological changes and mimics neuronal phenotype. J. Neurosci. Res. 77(2), 192-204 (2004).
    • (2004) J. Neurosci. Res. , vol.77 , Issue.2 , pp. 192-204
    • Neuhuber, B.1    Gallo, G.2    Howard, L.3
  • 48
    • 70849127052 scopus 로고    scopus 로고
    • Multipotent mesenchymal stem cells from amniotic fuid originate neural precursors with functional voltage-gated sodium channels
    • Mareschi K, Rustichelli D, Comunanza V et al.: Multipotent mesenchymal stem cells from amniotic fuid originate neural precursors with functional voltage-gated sodium channels. Cytotherapy 11(5), 534-547 (2009).
    • (2009) Cytotherapy , vol.11 , Issue.5 , pp. 534-547
    • Mareschi, K.1    Rustichelli, D.2    Comunanza, V.3
  • 49
    • 18844362410 scopus 로고    scopus 로고
    • Functional neural stem cells derived from adult bone marrow
    • Bonilla S, Silva A, Valdes L et al.: Functional neural stem cells derived from adult bone marrow. Neuroscience 133(1), 85-95 (2005).
    • (2005) Neuroscience , vol.133 , Issue.1 , pp. 85-95
    • Bonilla, S.1    Silva, A.2    Valdes, L.3
  • 50
    • 55049110117 scopus 로고    scopus 로고
    • Neural induction with neurogenin1 increases the therapeutic effects of mesenchymal stem cells in the ischemic brain
    • Kim SS, Yoo SW, Park TS et al.: Neural induction with neurogenin1 increases the therapeutic effects of mesenchymal stem cells in the ischemic brain. Stem Cells 26(9), 2217-2228 (2008).
    • (2008) Stem Cells , vol.26 , Issue.9 , pp. 2217-2228
    • Kim, S.S.1    Yoo, S.W.2    Park, T.S.3
  • 51
    • 67650472646 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor facilitates maturation of mesenchymal stem cell-derived dopamine progenitors to functional neurons
    • Trzaska KA, King CC, Li KY et al.: Brain-derived neurotrophic factor facilitates maturation of mesenchymal stem cell-derived dopamine progenitors to functional neurons. J. Neurochem. 110(3), 1058-1069 (2009).
    • (2009) J. Neurochem. , vol.110 , Issue.3 , pp. 1058-1069
    • Trzaska, K.A.1    King, C.C.2    Li, K.Y.3
  • 52
    • 57449101862 scopus 로고    scopus 로고
    • In vitro and in vivo characterization of neurally modifed mesenchymal stem cells induced by epigenetic modifers and neural stem cell environment
    • Alexanian AR, Maiman DJ, Kurpad SN, Gennarelli TA: In vitro and in vivo characterization of neurally modifed mesenchymal stem cells induced by epigenetic modifers and neural stem cell environment. Stem Cells Dev. 17(6), 1123-1130 (2008).
    • (2008) Stem Cells Dev. , vol.17 , Issue.6 , pp. 1123-1130
    • Alexanian, A.R.1    Maiman, D.J.2    Kurpad, S.N.3    Gennarelli, T.A.4
  • 53
    • 5444246148 scopus 로고    scopus 로고
    • Effcient generation of neural stem cell-like cells from adult human bone marrow stromal cells
    • Hermann A, Gastl R, Liebau S et al.: Effcient generation of neural stem cell-like cells from adult human bone marrow stromal cells. J. Cell Sci. 117(Pt 19), 4411-4422 (2004).
    • (2004) J. Cell Sci. , vol.117 , Issue.PART 19 , pp. 4411-4422
    • Hermann, A.1    Gastl, R.2    Liebau, S.3
  • 54
    • 33846428781 scopus 로고    scopus 로고
    • Epigenetic modifers promote effcient generation of neural-like cells from bone marrow-derived mesenchymal cells grown in neural environment
    • Alexanian AR: Epigenetic modifers promote effcient generation of neural-like cells from bone marrow-derived mesenchymal cells grown in neural environment. J. Cell Biochem. 100(2), 362-371 (2007).
    • (2007) J. Cell Biochem. , vol.100 , Issue.2 , pp. 362-371
    • Alexanian, A.R.1
  • 55
    • 0009482260 scopus 로고
    • Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
    • Towbin H, Staehelin T, Gordon J: Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl Acad. Sci. USA 76(9), 4350-4354 (1979).
    • (1979) Proc. Natl Acad. Sci. USA , vol.76 , Issue.9 , pp. 4350-4354
    • Towbin, H.1    Staehelin, T.2    Gordon, J.3
  • 57
    • 34249880066 scopus 로고    scopus 로고
    • Generation of germline-competent induced pluripotent stem cells
    • Okita K, Ichisaka T, Yamanaka S: Generation of germline-competent induced pluripotent stem cells. Nature 448(7151), 313-317 (2007).
    • (2007) Nature , vol.448 , Issue.7151 , pp. 313-317
    • Okita, K.1    Ichisaka, T.2    Yamanaka, S.3
  • 58
    • 36749043230 scopus 로고    scopus 로고
    • Induced pluripotent stem cell lines derived from human somatic cells
    • Yu J, Vodyanik MA, Smuga-Otto K et al.: Induced pluripotent stem cell lines derived from human somatic cells. Science 318(5858), 1917-1920 (2007).
    • (2007) Science , vol.318 , Issue.5858 , pp. 1917-1920
    • Yu, J.1    Vodyanik, M.A.2    Smuga-Otto, K.3
  • 59
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fbroblasts by defned factors
    • Takahashi K, Tanabe K, Ohnuki M et al.: Induction of pluripotent stem cells from adult human fbroblasts by defned factors. Cell 131(5), 861-872 (2007).
    • (2007) Cell , vol.131 , Issue.5 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3
  • 60
    • 67449156378 scopus 로고    scopus 로고
    • Induced pluripotent stem cells generated without viral integration
    • Eggenschwiler R, Cantz T: Induced pluripotent stem cells generated without viral integration. Hepatology 49(3), 1048-1049 (2009).
    • (2009) Hepatology , vol.49 , Issue.3 , pp. 1048-1049
    • Eggenschwiler, R.1    Cantz, T.2
  • 61
    • 55849117368 scopus 로고    scopus 로고
    • Generation of mouse induced pluripotent stem cells without viral vectors
    • Okita K, Nakagawa M, Hyenjong H, Ichisaka T, Yamanaka S: Generation of mouse induced pluripotent stem cells without viral vectors. Science 322(5903), 949-953 (2008).
    • (2008) Science , vol.322 , Issue.5903 , pp. 949-953
    • Okita, K.1    Nakagawa, M.2    Hyenjong, H.3    Ichisaka, T.4    Yamanaka, S.5
  • 62
    • 66049135249 scopus 로고    scopus 로고
    • Generation of induced pluripotent stem cells using recombinant proteins
    • Zhou H, Wu S, Joo JY et al.: Generation of induced pluripotent stem cells using recombinant proteins. Cell Stem Cell 4(5), 381-384 (2009).
    • (2009) Cell Stem Cell , vol.4 , Issue.5 , pp. 381-384
    • Zhou, H.1    Wu, S.2    Joo, J.Y.3
  • 63
    • 48349095740 scopus 로고    scopus 로고
    • Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors
    • Kim JB, Zaehres H, Wu G et al.: Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors. Nature 454(7204), 646-650 (2008).
    • (2008) Nature , vol.454 , Issue.7204 , pp. 646-650
    • Kim, J.B.1    Zaehres, H.2    Wu, G.3
  • 64
    • 70349206185 scopus 로고    scopus 로고
    • Induction of stem cell gene expression in adult human fbroblasts without transgenes
    • Page RL, Ambady S, Holmes WF et al.: Induction of stem cell gene expression in adult human fbroblasts without transgenes. Cloning Stem Cells 11(3), 417-426 (2009).
    • (2009) Cloning Stem Cells , vol.11 , Issue.3 , pp. 417-426
    • Page, R.L.1    Ambady, S.2    Holmes, W.F.3
  • 65
    • 14844321862 scopus 로고    scopus 로고
    • In vivo haematopoietic activity is induced in neurosphere cells by chromatin-modifying agents
    • Schmittwolf C, Kirchhof N, Jauch A et al.: In vivo haematopoietic activity is induced in neurosphere cells by chromatin-modifying agents. EMBO J. 24(3), 554-566 (2005).
    • (2005) EMBO J. , vol.24 , Issue.3 , pp. 554-566
    • Schmittwolf, C.1    Kirchhof, N.2    Jauch, A.3
  • 66
    • 48349122654 scopus 로고    scopus 로고
    • Pluripotency associated genes are reactivated by chromatin-modifying agents in neurosphere cells
    • Ruau D, Ensenat-Waser R, Dinger TC et al.: Pluripotency associated genes are reactivated by chromatin-modifying agents in neurosphere cells. Stem Cells 26(4), 920-926 (2008).
    • (2008) Stem Cells , vol.26 , Issue.4 , pp. 920-926
    • Ruau, D.1    Ensenat-Waser, R.2    Dinger, T.C.3
  • 67
    • 65349131822 scopus 로고    scopus 로고
    • Elevation of cAMP in mesenchymal stem cells transiently upregulates neural markers rather than inducing neural differentiation
    • Rooney GE, Howard L, O'Brien T, Windebank AJ, Barry FP: Elevation of cAMP in mesenchymal stem cells transiently upregulates neural markers rather than inducing neural differentiation. Stem Cells Dev. 18(3), 387-398 (2009).
    • (2009) Stem Cells Dev. , vol.18 , Issue.3 , pp. 387-398
    • Rooney, G.E.1    Howard, L.2    O'Brien, T.3    Windebank, A.J.4    Barry, F.P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.