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Volumn 45, Issue 12, 2010, Pages 6045-6051

Synthesis of novel α-santonin derivatives as potential cytotoxic agents

(9) Arantes, Francisco F P a Barbosa, Luiz C A a Maltha, Célia R A a Demuner, Antônio J a Marçal Da Costa, Patricia b Ferreira, José R O b Costa Lotufo, Letícia V b Moraes, Manoel O b Pessoa, Cláudia b

a FEDERAL UNIVERSITY OF VIÇOSA (Brazil)

b FEDERAL UNIVERSITY OF CEARÁ (Brazil)

Author keywords

methylene lactone; Cytotoxicity; Endoperoxide bridge; Parishin A synthesis; Sesquiterpene lactones

Indexed keywords

10ALPHA HYDROXY 3 OXO 1,7ALPHAH,6,11BETAH 13 ACETYLGUAIA 4 EN 6,12 OLIDE; 10ALPHA HYDROXY 3 OXO 1,7ALPHAH,6BETAH GUAIA 4,11 DIEN 6,12 OLIDE; 11,13 DEHYDROISOFOTOSANTONIC ACID; 11,13 DEHYDROMAZDASANTONIN; 13 ACETYLISOPHOTOSANTONIC ACID; 13 ACETYLLUMISANTONIN; 3 OXO 7ALPHAH,6,11BETAH 13 ACETYLEUDESMA 1,4 DIEN 6,12 OLIDE; ALPHA METHYLENE GAMMA LACTONE; ALPHA SANTONIN; CYTOTOXIC AGENT; DOXORUBICIN; ENDOPEROXIDE; PHENYLSELENYL LUMISANTONIN; SESQUITERPENE LACTONE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL MEMBRANE; CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; ERYTHROCYTE; HEMOLYSIS; IC 50; MOUSE; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; DRUG SCREENING ASSAYS, ANTITUMOR; HL-60 CELLS; HUMANS; MOLECULAR STRUCTURE; SANTONIN; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 78649328995 PISSN: 02235234 EISSN: 17683254 Source Type: Journal
DOI: 10.1016/j.ejmech.2010.10.003 Document Type: Article

Times cited : (32)

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