Short-term hyperglycaemia causes non-reversible changes in arterial gene expression in a fully 'switchable' in vivo mouse model of diabetes

Diabetologia

Volumn 53, Issue 12, 2010, Pages 2676-2687

  Zervou, S ^a,b   Wang, Y F ^b   Laiho, A ^c   Gyenesei, A ^c   Kytomaki L ^c   Hermann, R ^c   Abouna, S ^b   Epstein, D ^b   Pelengaris, S ^d   Khan, M ^b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF WARWICK   (United Kingdom)

^c Bioinformatics Unit   (Finland)

^d UNIVERSITY OF WARWICK   (United Kingdom)

Author keywords

Aorta; Cardiovascular; Diabetes; GeneChip arrays; Hyperglycaemia; Mouse

Indexed keywords

BONE MORPHOGENETIC PROTEIN RECEPTOR 2; CHOLESTEROL; COLLAGEN TYPE 1 ALPHA 1; CREATINE KINASE MM; CYCLIN D2; FATTY ACID BINDING PROTEIN 1; FATTY ACID BINDING PROTEIN 7; GELATINASE B; GENE PRODUCT; GLUCOSE; HEAT SHOCK PROTEIN 90; MYC PROTEIN; MYOZENIN 2; OSTEOMODULIN; PHOSPHOLAMBAN; PLASMINOGEN; STROMELYSIN; TRIACYLGLYCEROL; TROPONIN T2; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; VASCULOTROPIN; VOLTAGE GATED POTASSIUM CHANNEL; VON WILLEBRAND FACTOR; WNT INHIBITORY FACTOR 1;

ADULT ANIMAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; ARTERY CALCIFICATION; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; FEMALE; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; HYPOGLYCEMIA; IN VIVO STUDY; INFLAMMATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; WILD TYPE;

ANIMALS; ARTERIES; DIABETES MELLITUS, EXPERIMENTAL; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION; GENES, MYC; GLUCOSE; HYPERGLYCEMIA; INSULIN; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; MICE, TRANSGENIC; RECOVERY OF FUNCTION; TIME FACTORS;

EID: 78649325905     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-010-1887-5     Document Type: Article

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