Increased atherosclerosis in streptozotocin-induced diabetic mice

Journal of Clinical Investigation

Volumn 97, Issue 7, 1996, Pages 1767-1773

  Kunjathoor, Vidya V ^a   Wilson, Deborah L ^a   LeBoeuf, Renée C ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

diabetic complications; fatty streaks; genetics; hyperglycemia; vascular disease

Indexed keywords

CHOLESTEROL; CITRIC ACID; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; STREPTOZOCIN; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA ATHEROSCLEROSIS; AORTA SINUS; ARTICLE; ATHEROGENIC DIET; CONTROLLED STUDY; FEMALE; HYPERGLYCEMIA; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; STREPTOZOCIN DIABETES;

EID: 0029912398     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI118604     Document Type: Article

References (36)

1. Pyorala, K., M. Laakso, and M. Uusitupa. 1987. Diabetes and atherosclerosis: an epidemiologic view. Diabetes Metab, Rev. 3:463-524.
2. Bierman, E.L. 1992. George Lyman Duft Memorial Lecture. Atherogenesis in diabetes. Arterioscler, Thromb. 12:647-656.
3. Krolewski, A.S., E J. Kosinski, J.H. Warram, O.S. Leland, E.J. Busick, A.C. Asmal, L.I. Rand, A.R. Christlieb, R.F. Bradley, and C.R. Kahn. 1987. Magnitude and determinants of coronary artery disease in juvenile-onset, insulin-dependent diabetes mellitus. Am. J. Cardiol. 59:750-755.
4. Andersen, A.R., J.S. Christiansen, J.K. Andersen. S. Kreiner, and T Deckert. 1983. Diabetic nephropathy in type I (insulin-dependent) diabetes: an cpidcmiological study. Diabetologia. 25:496-501.
5. Inoguchi, T., P. Xia, M. Kunisaki, S. Higashi, E.P. Feener, and G L. King. 1994. Insulin's effect on protein kinase C and diacylglycerol induced by diabetes and glucose m vascular tissues. Am J. Physiol 267:E369-E379.
6. Xia. P., T. Inoguchi. T.S. Kern, R.L. Engerman. P.J. Oates, and G.L. King. 1994. Characterization of the mechanism for the chronic activation of diacylglycerol-protein kinase C pathway in diabetes and hypergalactosemia. Diabetes. 43.1122-1129.
7. Olgemoller, B., and E. Schleicher. 1993. Alterations of glomerular matrix proteins in the pathogenesis of diabetic nephropathy. Clin. Invest. 71:S13-S19.
8. Still, W.J.S., J.M. Martin, and W.H. Gregor. 1964 The effect of alloxan diabetes on experimental atherosclerosis in the rat. Exp. Mol. Pathol. 3:141-147.
9. Nordestgaard, E.G., S. Stender, and K. Kjeldsen. 1988. Reduced atherogenesis in cholesterol-fed diabetic rabbits. Giant lipoproteins do not enter the arterial wall. Arteriosclerosis. 8.421-28.
10. Miller, R.A., and R.B. Wilson. 1984. Atherosclerosis and myocardial ischemic lesions in alloxan-diabetic rabbits fed a low cholesterol diet. Arteriosclerosis. 4 586-591.
11. The Diabetes Control and Complications Trial Research Group. 1993 The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N. Engl J. Med. 329:977-986.
12. Hunt. J.V., M.A. Bottoms, K. Clare, J.T. Skamarauskas, and M.J Mitchinson. 1994. Glucose oxidation and low-density lipoprotein-induced macrophage ceroid accumulation: possible implications for diabetic atherosclerosis. Biochem. J 300:243-249.
13. Bierman, E.L., and J.A. Glomsct. 1992. Disorders of lipid metabolism. In Williams Textbook of Endocrinology. 8th edition. J.D. Wilson and D.W. Foster, editors. W.B. Saunders, Philadelphia.
14. Lyons, T.J. 1992. Lipoprotein glycation and us metabolic complications Diabetes. 41(Suppl. 2):67-73.
15. Biesbroeck, R.C., J J. Albers, P.W. Wahl. C.R. Weinberg, M.L. Basset, and E.L. Bierman. 1982. Abnormal composition of high density lipoproieins in non-insulin-dependent diabetics. Diabetes. 31:126-131.
16. Barbaras, R , P. Puchois, J.C Fruchart. and G. Ailhaud. 1987. Cholesterol efflux from cultured adipose cells is mediated by Lp AI particles but not LpAI:AII particles. Biochem Biophys. Res. Commun. 142:63-69.
17. Oram, J.F. 1995. Can insulin promote atherogenesis by altering cellular cholesterol metabolism? J. Lab. Clin Med. 126-229-230.
18. Paigen. B., B.Y. Ishida, J Verstuyft, R.B. Winters, and D. Albee. 1990 Atherosclerosis susceptibility differences among progenitors of recombinant inbred strains of mice Arteriosclerosis. 10:316-323.
19. LeBoeuf, R.C., M. Caldwell, and E. Kirk, 1994. Regulation by nutritional status of lipids and apolipoproteins A-I, A-II, and A-IV in inbred mice. J. Lipid Res. 35:121-133.
20. Izzo, C . F Grillo. and E. Murador. 1978. Improved method for determination of high-density-lipoprotein cholesterol. I. Isolation of high-density-lipoproteins by using polyethylene glycol 6000. Clin Chem. 27:371-374.
21. Foich. J., M. Lees, and G.H. Sloane Stanley. 1957. A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem. 226:497-509.
22. Carr, T.P., C.J. Andresen, and L.L. Rudel 1993. Enzymatic determination of triglyceride, free cholesterol, and total cholesterol in tissue lipid extracts Clin. Biochem. 26:39-42
23. Paigen. B., A. Morrow, P.A Holmes, D. Mitchell, and R.A. Williams. 1987 Quantitative assessment of atherosclerotic lesions in mice Atherosclerosis. 68:231-240.
24. Hsu, S.M., L. Raine, and H. Fanger. 1981. Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedure. J. Histochem. Cytochem. 29: 577-580.
25. Bonnevic-Nielsen. V., M.W. Steffes, and A. Lcrnmark. 1981. A major loss in islet mass and B-cell function precedes hyperglycermia in mice given multiple low doses of streptozotocin. Diabetes. 30.424-429.
26. LeBoeuf, R.C., M.H. Doolittle, A. Montcalm, D.C. Martin, K. Reue, and A.J. Lusis. 1990. Phenotypic characterization of the Ath-1 gene controlling high density lipoprotein levels and susceptibility to atherosclerosis. J. Lipid Res. 31.91-101.
27. Stewart-Phillips. J.L., and J. Lough. 1991. Pathology and atherosclerosis in cholesterol-fed susceptible mice. Atherosclerosis 90:211-218.
28. Nishina. P.M., J Verstuyft. and B. Paigen. 1990. Synthetic low and high fat diets for the study of atherosclerosis in the mouse. J. Lipid Res. 31:859-869.
29. Nishina, P M., J.K. Naggert, J. Verstuyft, and B. Paigen. 1994. Atherosclerosis in genetically obese mice the mutant obese, diabetes, fat, tubby, and lethal yellow. Metab. Clin. Exp. 43-554-558.
30. Liao. F., A Andalibi. F.C. deBeer, A.M. Fogelman, and A J. Lusis. 1993 Genetic control of inflammatory gene induction and NF-κB-like transcription factor activation in response to an atherogenic diet in mice. J. Clin, invest. 91.2572-2579.
31. Mullarkey, C J., D. Edelstein, and M Brownlee. 1990. Free radical generation by early glycation products: a mechanism for accelerated atherogenesis in diabetes. Biochem. Biophys. Res. Commun. 173:932-939.
32. Baynes, J.W. 1991. Role of oxidative stress in development of complications in diabetes. Diabetes 40:405-412.
33. Stary, H.C., A.B. Chandler. S. Glagov, J.R. Guyton, W. Insull, M.E. Rosenfeld, S.A. Schaffet, C J. Schwartz, W.D. Wagner, and R.W. Wissler. 1994. A definition of initial, fatty streak, and intermediate lesions of atherosclerosis. Circulation. 89 2462-2478.
34. Qiao, J -H., P.-Z. Xic, M.C. Fishbein, J. Kreuzer, T.A. Drake. L.L. Demer, and A.J. Lusis. 1994. Pathology of atheromatous lesions in inbred and genetically engineered mice. Genetic determination of arterial calcification. Arierioscler. Thromb. 14:1480-1497.
35. Nakashima, Y., A.S. Plump, E.W. Raines. J.L. Breslow, and R. Ross, 1994. ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree Arterioscler. Thromb. 14:133-140.
36. Pfeiffer, A , and H. Schatz 1995. Diabetic microvascular complications and growth factors Endocrinol. Diabetes. 103:7-14.