Synthesis of some new 1,2,4-triazoles starting from isonicotinic acid hydrazide and evaluation of their antimicrobial activities

European Journal of Medicinal Chemistry

Volumn 44, Issue 11, 2009, Pages 4362-4366

  Bayrak, Hacer ^a   Demirbas, Ahmet ^a   Demirbas, Neslihan ^a   Karaoglu, Sengül Alpay ^b  

^a KARADENIZ TECHNICAL UNIVERSITY   (Turkey)

^b RECEP TAYYIP ERDOGAN UNIVERSITY   (Turkey)

Author keywords

1,2,4 Triazole; 1,3,4 Oxadiazole; Antimicrobial activity; Isonicotinic acid hydrazide

Indexed keywords

3 (ETHYLTHIO) 5 PYRIDIN 4 YL 4H 1,2,4 TRIAZOL 4 AMINE; 3 [(4 METHYLPIPERAZIN 1 YL)METHYL] 5 PYRIDIN 4 YL 1,3,4 OXADIAZOLE 2(3H) THIONE; 3 [[(2 MORPHOLIN 4 YLETHYL)AMINO]METHYL] 5 PYRIDIN 4 YL 1,3,4 OXADIAZOLE 2(3H) THIONE; 4 [5 (ETHYLTHIO) 1,3,4 OXADIAZOL 2 YL]PYRIDINE; 4 [[(4 FLUOROPHENYL)METHYLENE]AMINO] 5 PYRIDIN 4 YL 2 [(4 METHYLPIPERAZIN 1 YL)METHYL 2,4 DIHYDRO 3H 1,2,4 TRIAZOLE 3 THIONE; 4 [[(4 FLUOROPHENYL)METHYLENE]AMINO] 5 PYRIDIN 4 YL 4H 1,2,4 TRIAZOLE 3 THIONE; 4 [[1H INDOL 3 YLMETHYLENE]AMINO] 5 PYRIDIN 4 YL 4H 1,2,4 TRIAZOLE 3 THIONE; 4 AMINO 2 (MORPHOLIN 4 YLMETHYL) 5 PYRIDIN 4 YL 2,4 DIHYDRO 3H 1,2,4 TRIAZOLE 3 THIONE; 4 AMINO 2 [(4 METHYLPIPERAZIN 1 YL)METHYL] 5 PYRIDIN 4 YL 2,4 DIHYDRO 3H 1,2,4 TRIAZOLE 3 THIONE; 4 AMINO 2 [[(2 MORPHOLIN 4 YLETHYL)AMINO]METHYL] 5 PYRIDIN 4 YL 2,4 DIHYDRO 3H 1,2,4 TRIAZOLE 3 THIONE; 4 AMINO 5 PYRIDIN 4 YL 4H 1,2,4 TRIAZOLE 3 THIOL; 5 PYRIDIN 4 YL 1,3,4 OXADIAZOLE 2 THIOL; AMPICILLIN; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; CARBON DISULFIDE; FLUCONAZOLE; ISONICOTINIC ACID; MANNICH BASE; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBIOTIC SENSITIVITY; ANTIFUNGAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; BACILLUS CEREUS; CANDIDA ALBICANS; CANDIDA TROPICALIS; CHEMICAL REACTION; CONTROLLED STUDY; DRUG SCREENING; DRUG SYNTHESIS; ENTEROCOCCUS FAECALIS; ESCHERICHIA COLI; NONHUMAN; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS; YERSINIA PSEUDOTUBERCULOSIS;

ANTI-INFECTIVE AGENTS; BACTERIA; ISONIAZID; MANNICH BASES; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; OXADIAZOLES; STRUCTURE-ACTIVITY RELATIONSHIP; TRIAZOLES; YEASTS;

EID: 70349774242     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2009.05.022     Document Type: Article

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