Lysine deacetylases are produced in pancreatic beta cells and are differentially regulated by proinflammatory cytokines

Diabetologia

Volumn 53, Issue 12, 2010, Pages 2569-2578

  Lundh, M ^a   Christensen, D P ^a   Rasmussen, D N ^a   Mascagni, P ^b   Dinarello, C A ^c   Billestrup, N ^a   Grunnet, L G ^a   Mandrup Poulsen, T ^a,d,e  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b Italfarmaco SpA   (Italy)

^c UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^d HAGEDORN RESEARCH INSTITUTE   (Denmark)

^e KAROLINSKA INSTITUTE   (Sweden)

Author keywords

HDAC; Histone; IL 1; KDAC; Lysine deacetylase inhibitors

Indexed keywords

ACYLTRANSFERASE; CYTOKINE; GAMMA INTERFERON; GIVINOSTAT; HISTONE DEACETYLASE; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 11; HISTONE DEACETYLASE 2; HISTONE DEACETYLASE 6; INSULIN; INTERLEUKIN 1BETA; LYSINE DEACETYLASE; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL CELL CULTURE; APOPTOSIS; ARTICLE; CELL LINE; CELL PROTECTION; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; INSULIN RELEASE; KDAC GENE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM;

ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; CELLS, CULTURED; CYTOKINES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HISTONE DEACETYLASE INHIBITORS; HISTONE DEACETYLASES; HUMANS; INFLAMMATION MEDIATORS; INSULIN-SECRETING CELLS; LYSINE; RATS; RATS, WISTAR; TIME FACTORS;

EID: 78649321082     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-010-1892-8     Document Type: Article

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