SARS spike protein induces phenotypic conversion of human B cells to macrophage-like cells

Molecular Immunology

Volumn 47, Issue 16, 2010, Pages 2575-2586

  Chiang, Shu Fen ^a   Lin, Tze Yi ^b   Chow, Kuan Chih ^a   Chiou, Shiow Her ^a  

^a NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

B cell; Hypoxia; Mac 1 (CD11b); Macrophage; SARS associated coronavirus

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN BETA; CD11B ANTIGEN; CD19 ANTIGEN; CD68 ANTIGEN; HYPOXIA INDUCIBLE FACTOR 1; INTERCELLULAR ADHESION MOLECULE 1; KRUPPEL LIKE FACTOR 5; LIGAND; SARS SPIKE PROTEIN; SOMATOMEDIN BINDING PROTEIN 3; STAT PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; B CELL LYMPHOMA; B LYMPHOCYTE; BACULOVIRUS; CONTROLLED STUDY; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; GENETIC TRANSDUCTION; HYPOXIA; LYMPHOMA CELL; MACROPHAGE; MALE; MOUSE; NONHUMAN; PHAGOCYTOSIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SARS CORONAVIRUS; VIRUS RECOMBINANT;

ANIMALS; B-LYMPHOCYTES; CELL LINE; GENE EXPRESSION PROFILING; HUMANS; LYMPHOMA, B-CELL; MACROPHAGES; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED BALB C; PHENOTYPE; RECOMBINANT PROTEINS; SARS VIRUS; VIRAL ENVELOPE PROTEINS;

CORONAVIRUS; SARS CORONAVIRUS;

EID: 78649318694     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2010.06.014     Document Type: Article

References (50)

1. Akashi K., Traver D., Miyamoto T., Weissman I.L. A clonogenic common myeloid progenitor that gives rise to all myeloid lineages. Nature 2000, 404:193-197.
2. Alcivar A., Hu S., Tang J., Yang X. DEDD and DEDD2 associate with caspase-8/10 and signal cell death. Oncogene 2003, 22:291-297.
3. Alexander W.S. Cytokines in hematopoiesis. Int. Rev. Immunol. 1998, 16:651-682.
4. Anand R.J., Gribar S.C., Li J., Kohler J.W., Branca M.F., Dubowski T., Sodhi C.P., Hackam D.J. Hypoxia causes an increase in phagocytosis by macrophages in a HIF-1α-dependent manner. J. Leukoc. Biol. 2007, 82:1257-1265.
5. Chang Y.J., Liu C.Y., Chiang B.L., Chao Y.C., Chen C.C. Induction of IL-8 release in lung cells via activator protein-1 by recombinant baculovirus displaying severe acute respiratory syndrome-coronavirus spike proteins: identification of two functional regions. J. Immunol. 2004, 173:7602-7614.
6. Chen J.T., Lin T.S., Chow K.C., Huang H.H., Chiou S.H., Chiang S.F., Chen H.C., Chuang T.L., Lin T.Y., Chen C.Y. Cigarette smoking induces overexpression of HGF in type II pneumocytes and lung cancer cells. Am. J. Respir. Cell Mol. Biol. 2006, 34:264-273.
7. Chiu C.F., Chow K.C., Lin T.Y., Tsai M.H., Shih C.M., Chen L.M. Involvement of virus infection in patients with histiocytic necrotizing lymphadenitis in Taiwan-detection of Epstein-Barr virus, type I human T-cell lymphotropic virus and parvovirus B19. Am. J. Clin. Pathol. 2000, 113:774-781.
8. Chow K.C., Hsiao C.H., Lin T.Y., Chen C.L., Chiou S.H. Detection of severe acute respiratory syndrome-associated coronavirus in pneumocytes of the lung. Am. J. Clin. Pathol. 2004, 121:574-580.
9. Claviez A., Tiemann M., Lüders H., Krams M., Parwaresch R., Schellong G., Dörffel W. Impact of latent Epstein-Barr virus infection on outcome in children and adolescents with Hodgkin's lymphoma. J. Clin. Oncol. 2005, 23:4048-4056.
10. Corti M., Brody A.R., Harrison J.H. Isolation and primary culture of murine alveolar type II cells. Am. J. Respir. Cell Mol. Biol. 1996, 14:309-315.
11. Ding Y., Wang H., Shen H., Li Z., Geng J., Han H., Cai J., Li X., Kang W., Weng D., Lu Y., Wu D., He L., Yao K. The clinical pathology of severe acute respiratory syndrome (SARS): a report from China. J. Pathol. 2003, 200:282-289.
12. Ding Y., He L., Zhang Q., Huang Z., Che X., Hou J., Wang H., Shen H., Qiu L., Li Z., Geng J., Cai J., Han H., Li X., Kang W., Weng D., Liang P., Jiang S. Organ distribution of severe acute respiratory syndrome (SARS) associated coronavirus (SARS-CoV) in SARS patients: implications for pathogenesis and virus transmission pathways. J. Pathol. 2004, 203:622-630.
13. Granata R., Trovato L., Garbarino G., Taliano M., Ponti R., Sala G., Ghidoni R., Ghigo E. Dual effects of IGFBP-3 on endothelial cell apoptosis and survival: involvement of the sphingolipid signaling pathways. FASEB J. 2004, 18:1456-1458.
14. Grutkoski P.S., Chen Y., Chung C.S., Ayala A. Sepsis-induced SOCS-3 expression is immunologically restricted to phagocytes. J. Leukoc. Biol. 2003, 74:916-922.
15. Gu J., Gong E., Zhang B., Zheng J., Gao Z., Zhong Y., Zou W., Zhan J., Wang S., Xie Z., Zhuang H., Wu B., Zhong H., Shao H., Fang W., Gao D., Pei F., Li X., He Z., Xu D., Shi X., Anderson V.M., Leong A.S. Multiple organ infection and the pathogenesis of SARS. J. Exp. Med. 2005, 202:415-424.
16. Gupta M., Gupta S.K., Hoffman B., Liebermann D.A. Gadd45a and Gadd45b protect hematopoietic cells from UV-induced apoptosis via distinct signaling pathways, including p38 activation and JNK inhibition. J. Biol. Chem. 2006, 281:17552-17558.
17. Heyworth C., Pearson S., May G., Enver T. Transcription factor-mediated lineage switching reveals plasticity in primary committed progenitor cells. EMBO J. 2002, 21:3770-3781.
18. Horny H.P., Wehrmann M., Steinke B., Kaiserling E. Assessment of the value of immunohistochemistry in the subtyping of acute leukemia on routinely processed bone marrow biopsy specimens with particular reference to macrophage-associated antibodies. Hum. Pathol. 1994, 25:810-814.
19. Hsu S.M., Xie S.S., Hsu P.L. Cultured Reed-Sternberg cells HDLM-1 and KM-H2 can be induced to become histiocyte-like cells. H-RS cells are not derived from lymphocytes. Am. J. Pathol. 1990, 137:353-367.
20. Itoh N., Yonehara S., Ishii A., Yonehara M., Mizushima S., Sameshima M., Hase A., Seto Y., Nagata S. The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis. Cell 1991, 66:233-243.
21. Keegan T.H., Glaser S.L., Clarke C.A., Gulley M.L., Craig F.E., Digiuseppe J.A., Dorfman R.F., Mann R.B., Ambinder R.F. Epstein-Barr virus as a marker of survival after Hodgkin's lymphoma: a population-based study. J. Clin. Oncol. 2005, 23:7604-7613.
22. Kerr J.F.R., Wyllie A.H., Currie A.R. Apoptosis: a basic biological phenomenon with wide ranging implications in tissue kinetics. Br. J. Cancer 1972, 26:239-257.
23. + B1 cells to a macrophage-like morphology induced by gamma interferon and inhibited by interleukin-4. Clin. Diagn. Lab. Immunol. 2002, 9:1169-1174.
24. Kovács-Sólyom F., Blaskó A., Fajka-Boja R., Katona R.L., Végh L., Novák J., Szebeni G.J., Krenács L., Uher F., Tubak V., Kiss R., Monostori E. Mechanism of tumor cell-induced T-cell apoptosis mediated by galectin-1. Immunol. Lett. 2010, 127:108-118.
25. Laslo P., Spooner C.J., Warmflash A., Lancki D.W., Lee H.J., Sciammas R., Gantner B.N., Dinner A.R., Singh H. Multilineage transcriptional priming and determination of alternate hematopoietic cell fates. Cell 2006, 126:755-766.
26. Loose M., Patient R. Global genetic regulatory networks controlling hematopoietic cell fates. Curr. Opin. Hematol. 2006, 13:229-236.
27. Liao Q., Ozawa F., Friess H., Zimmermann A., Takayama S., Reed J.C., Kleeff J., Büchler M.W. The anti-apoptotic protein BAG-3 is overexpressed in pancreatic cancer and induced by heat stress in pancreatic cancer cell lines. FEBS Lett. 2001, 503:151-157.
28. Liberek T., Chmielewski M., Lichodziejewska-Niemierko M., Lewandowski K., Rutkowski B. Transmigration of blood leukocytes into the peritoneal cavity is related to the upregulation of ICAM-1 (CD54) and Mac-1 (CD11b/CD18) adhesion molecules. Perit. Dial. Int. 2004, 24:139-146.
29. Nakajima H., Kizaki M., Sonoda A., Mori S., Harigaya K., Ikeda Y. Retinoids (all-trans and 9-cis retinoic acid) stimulate production of macrophage colony-stimulating factor and granulocyte-macrophage colony-stimulating factor by human bone marrow stromal cells. Blood 1994, 84:4107-4115.
30. Ng W.F., To K.F., Lam W.W., Ng T.K., Lee K.C. The comparative pathology of severe acute respiratory syndrome and avian influenza A subtype H5N1-a review. Hum. Pathol. 2006, 37:381-390.
31. Nicholls J.M., Poon L.L., Lee K.C., Ng W.F., Lai S.T., Leung C.Y., Chu C.M., Hui P.K., Mak K.L., Lim W., Yan K.W., Chan K.H., Tsang N.C., Guan Y., Yuen K.Y., Peiris J.S. Lung pathology of fatal severe acute respiratory syndrome. Lancet 2003, 361:1773-1778.
32. Orkin S.H. Diversification of haematopoietic stem cells to specific lineages. Nat. Rev. Genet. 2000, 1:57-64.
33. Rich T., Watson C.J., Wyllie A. Apoptosis: the germs of death. Nat. Cell Biol. 1999, 1:E69-E71.
34. Reddy V.A., Iwama A., Iotzova G., Schulz M., Elsasser A., Vangala R.K., Tenen D.G., Hiddemann W., Behre G. Granulocyte inducer C/EBPalpha inactivates the myeloid master regulator PU.1: possible role in lineage commitment decisions. Blood 2002, 100:483-490.
35. Re F., Arpinati M., Testoni N., Ricci P., Terragna C., Preda P., Ruggeri D., Senese B., Chirumbolo G., Martelli V., Urbini B., Baccarani M., Tura S., Rondelli D. Expression of CD86 in acute myelogenous leukemia is a marker of dendritic/monocytic lineage. Exp. Hematol. 2002, 30:126-134.
36. Shieh W.J., Hsiao C.H., Paddock C.D., Guarner J., Goldsmith C.S., Tatti K., Packard M., Mueller L., Wu M.Z., Rollin P., Su I.J., Zaki S.R. Immunohistochemical, in situ hybridization, and ultrastructural localization of SARS-associated coronavirus in lung of a fatal case of severe acute respiratory syndrome in Taiwan. Hum. Pathol. 2005, 36:303-309.
37. Shimabukuro-Vornhagen A., Haverkamp H., Engert A., Balleisen L., Majunke P., Heil G., Eich H.T., Stein H., Diehl V., Josting A. Lymphocyte-rich classical Hodgkin's lymphoma: clinical presentation and treatment outcome in 100 patients treated within German Hodgkin's Study Group trials. J. Clin. Oncol. 2005, 23:5739-5745.
38. Sieweke M.H., Graf T. A transcription factor party during blood cell differentiation. Curr. Opin. Genet. Dev. 1998, 8:545-551.
39. Song G., Ming Y., Mao Y., Bao S., Ouyang G. Osteopontin prevents curcumin-induced apoptosis and promotes survival through Akt activation via alpha v beta 3 integrins in human gastric cancer cells. Exp. Biol. Med. 2008, 233:1537-1545.
40. Spencker T., Neumann D., Strasser A., Resch K., Martin M. Lineage switch of a mouse pre-B-cell line (SPMG-1) to macrophage-like cells after incubation with phorbol ester and calcium ionophore. Biochem. Biophys. Res. Commun. 1995, 216:540-548.
41. Stanley E.R., Jubinsky P.T. Factors affecting the growth and differentiation of haemopoietic cells in culture. Clin. Hematol. 1984, 13:329-348.
42. Tanaka T., Wu G.E., Paige C.J. Characterization of the B cell-macrophage lineage transition in 70Z/3 cells. Eur. J. Immunol. 1994, 24:1544-1548.
43. Trepicchio W.L., Bozza M., Pedneault G. Recombinant human IL-11 attenuates the inflammatory response through down-regulation of proinflammatory cytokine release and nitric oxide production. J. Immunol. 1996, 157:3627-3634.
44. Umiel T., Pattengale P., Weinberg K. Recombination activating gene-1 (RAG-1) expression in all differentiation stages of B-lineage precursor acute lymphoblastic leukemia. Leukemia 1993, 7:435-440.
45. Wang D., D'Costa J., Civin C.I., Friedman A.D. C/EBPalpha directs monocytic commitment of primary myeloid progenitors. Blood 2006, 108:1223-1229.
46. Weiss L.M., Strickler J.G., Warnke R.A., Purtilo D.T., Sklar J. Epstein-Barr viral DNA in tissues of Hodgkin's disease. Am. J. Pathol. 1987, 129:86-91.
47. Wilson H.M., Lesnikov V., Plymate S.R., Ward J., Deeg H.J. High IGFBP-3 levels in marrow plasma in early-stage MDS: effects on apoptosis and hemopoiesis. Leukemia 2005, 19:580-585.
48. Xie H., Ye M., Feng R., Graf T. Stepwise reprogramming of B cells into macrophages. Cell 2004, 117:663-676.
49. Zhan J., Deng R., Tang J., Zhang B., Tang Y., Wang J.K., Li F., Anderson V.M., McNutt M.A., Gu J. The spleen as a target in severe acute respiratory syndrome. FASEB J. 2006, 20:2321-2328.
50. Zukerberg L.R., Collins A.B., Ferry J.A., Harris N.L. Coexpression of CD15 and CD20 by Reed-Sternberg cells in Hodgkin's disease. Am. J. Pathol. 1991, 139:475-483.