Osteopontin prevents curcumin-induced apoptosis and promotes survival through akt activation via αvβ3 integrins in human gastric cancer cells

Experimental Biology and Medicine

Volumn 233, Issue 12, 2008, Pages 1537-1545

  Song, Gang ^a   Ming, Yanlin ^a   Mao, Yubin ^a   Bao, F Shideng ^a   Ouyang, Gaoliang ^a  

^a XIAMEN UNIVERSITY   (China)

Author keywords

Akt; Apoptosis; Curcumin; Gastric cancer; Osteopontin (OPN)

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CURCUMIN; MONOCLONAL ANTIBODY LM 609; OSTEOPONTIN; PHOSPHATIDYLINOSITOL 3 KINASE; VITRONECTIN RECEPTOR; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; CHROMONE DERIVATIVE; ENZYME INHIBITOR; MORPHOLINE DERIVATIVE; PROTEIN KINASE B; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CANCER GROWTH; CARCINOGENESIS; CELL STRAIN SGC7901; CELL SURVIVAL; CONTROLLED STUDY; DRUG BINDING SITE; HUMAN; HUMAN CELL; SERUM; STOMACH CANCER; CELL CLONE; CULTURE MEDIUM; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; METABOLISM; PATHOLOGY; STOMACH TUMOR; TIME; TUMOR CELL LINE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; APOPTOSIS; CELL LINE, TUMOR; CELL SURVIVAL; CHROMONES; CLONE CELLS; CULTURE MEDIA, SERUM-FREE; CURCUMIN; ENZYME INHIBITORS; HUMANS; INTEGRIN ALPHAVBETA3; MORPHOLINES; OSTEOPONTIN; PROTO-ONCOGENE PROTEINS C-AKT; RECOMBINANT PROTEINS; STOMACH NEOPLASMS; TIME FACTORS;

EID: 58749094152     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.3181/0805-RM-164     Document Type: Article

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