A review on the methods of preparation of pharmaceutical nanoparticles

Pharmaceutical Sciences

Volumn 15, Issue 4, 2009, Pages 303-314

  Adibkia, K ^a,b   Barzegar Jalali, Mohammad ^a,b   Nokhodchi, A ^f   Siahi Shadbad, M R ^f   Omidi, Y ^a,b   Javadzadeh, Y ^a,c   Mohammadi, G ^d,e  

^a TABRIZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b TABRIZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c TABRIZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^d TABRIZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^e KERMANSHAH UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^f NONE

Author keywords

Commercialization; Method of preparation; Pharmaceutical aspects; Pharmaceutical nanoparticles; Review

Indexed keywords

NANOPARTICLE; POLYMER; SOLVENT;

ARTICLE; BIOCOMPATIBILITY; CELL SIZE; DRUG DELIVERY SYSTEM; FREEZE DRYING; MACROMOLECULE; NANOTECHNOLOGY; PHYSICAL CHEMISTRY; POLYMERIZATION; PRECIPITATION; SUSTAINED RELEASE PREPARATION;

EID: 78649302786     PISSN: 1735403X     EISSN: 23832886     Source Type: Journal    
DOI: None     Document Type: Article

References (75)

1. Douglas S.J., Davis S.S., Illum L. Nanoparticles in drug delivery, Crit Rev. Ther. Drug Carrier Syst., 1987, 3: 233-261.
2. Lockman P.R., Mumper R.J., Khan M.A., Allen D.D. Nanoparticle technology for drug delivery across the blood-brain barrier, Drug Dev. Ind. Pharm., 2002, 28: 1-13.
3. Xia X., Hu Z., Marquez M. Physically bonded nanoparticle networks: a novel drug delivery system, J. Control Release, 2005, 103: 21-30.
4. Kreuter J. Nanoparticles - a historical perspective, Int. J. Pharm., 2007, 331: 1-10.
5. Kreuter J. Nanoparticles and nanocapsules - new dosage forms in the nanometer size range, Pharm. Acta Helv., 1978, 53: 33-39.
6. Barzegar-Jalali M., Adibkia K., Valizadeh H., Shadbad M.R., Nokhodchi A., Omidi Y., Mohammadi G., Nezhadi S.H., Hasan M. Kinetic analysis of drug release from nanoparticles, J. Pharm. Pharm. Sci., 2008, 11: 167-177.
7. Paolicelli P., de la F.M., Sanchez A., Seijo B., Alonso M.J. Chitosan nanoparticles for drug delivery to the eye, Expert. Opin. Drug Deliv., 2009, 6: 239-253.
8. Tan M.L., Choong P.F., Dass C.R. Cancer, chitosan nanoparticles and catalytic nucleic acids, J. Pharm. Pharmacol., 2009, 61: 3-12.
9. Agnihotri S.A., Mallikarjuna N.N., Aminabhavi T.M. Recent advances on chitosan-based micro- and nanoparticles in drug delivery, J. Control Release, 2004, 100: 5-28.
10. Rytting E., Nguyen J., Wang X., Kissel T. Biodegradable polymeric nanocarriers for pulmonary drug delivery, Expert. Opin. Drug Deliv., 2008, 5: 629-639.
11. Mohamed F., van der Walle C.F. Engineering biodegradable polyester particles with specific drug targeting and drug release properties, J. Pharm. Sci., 2008, 97: 71-87.
12. Astete C.E., Sabliov C.M. Synthesis and characterization of PLGA nanoparticles, J. Biomater. Sci. Polym. Ed, 2006, 17: 247-289.
13. Araujo J., Gonzalez E., Egea M.A., Garcia M.L., Souto E.B. Nanomedicines for ocular NSAIDs: Safety on drug delivery, Nanomedicine., 2009, In Press.
14. Nagarwal R.C., Kant S., Singh P.N., Maiti P., Pandit J.K. Polymeric Nanoparticulate System: A Potential Approach for Ocular Drug Delivery, J. Control Release, 2009, In Press.
15. Agarwal A., Lariya N., Saraogi G., Dubey N., Agrawal H., Agrawal G.P. Nanoparticles as novel carrier for brain delivery: a review, Curr. Pharm. Des, 2009, 15: 917-925.
16. Allemann E., Gurny R., Doelker E. Drug-loaded nanoparticles - Preparation methods and drug targeting issues, Eur. J. Pharm. Biopharm., 1993, 39: 173-191.
17. De Jaeghere F., Doelker E., Gurny R., in Encyclopedia of controlled drug delivery, E.Mathiowitz Ed.; John Wiley & Sons, Inc., New York. 1999, 641.
18. Birrenbach G., Speiser P. Micelles and their use as adjuvants in immunology, J. Pharm. Sci., 1976, 65: 1763-1766.
19. Poupaert J.H., Couvreur P. A computationally derived structural model of doxorubicin interacting with oligomeric polyalkylcyanoacrylate in nanoparticles, J. Control Release, 2003, 92: 19-26.
20. Pinto-Alphandary H., Balland O., Couvreur P. A new method to isolate polyalkylcyanoacrylate nanoparticle preparations, J. Drug Target, 1995, 3: 167-169.
21. Chan V., Liu K.K., Le V.C., Ju B.F., Leong K.W. Bioadhesive characterization of poly(methylidene malonate 2.12) microparticle on model extracellular matrix, Biomaterials, 2004, 25: 4327-4332.
22. Le V.C., Quaglia F., Dreux M., Ounnar S., Breton P., Bru N., Couvreur P., Fattal E. Novel microparticulate system made of poly(methylidene malonate 2.1.2), Biomaterials, 2001, 22: 2229-2238.
23. Lescure F., Seguin C., Breton P., Bourrinet P., Roy D., Couvreur P. Preparation and characterization of novel poly(methylidene malonate 2.1.2.)-made nanoparticles, Pharm. Res., 1994, 11: 1270-1277.
24. Kreuter J., Speiser P. New adjuvants on a polymethylmethacrylate base, Infect. Immun., 1976, 13: 210
25. Kreuter J. Nanoparticles as adjuvants for vaccines, Pharm. Biotechnol., 1995, 6: 463-472.
26. Voltan R., Castaldello A., Brocca-Cofano E., Altavilla G., Caputo A., Laus M., Sparnacci K., Ensoli B., Spaccasassi S., Ballestri M., Tondelli L. Preparation and characterization of innovative protein-coated poly(methylmethacrylate) core-shell nanoparticles for vaccine purposes, Pharm. Res., 2007, 24: 1870-1882.
27. Kong H., Jang J. Antibacterial properties of novel poly(methyl methacrylate) nanofiber containing silver nanoparticles, Langmuir, 2008, 24: 2051-2056.
28. Kratz F. Albumin as a drug carrier: Design of prodrugs, drug conjugates and nanoparticles, J. Control Release, 2008,
29. Haidar Z.S., Hamdy R.C., Tabrizian M. Protein release kinetics for core-shell hybrid nanoparticles based on the layer-by-layer assembly of alginate and chitosan on liposomes, Biomaterials, 2008, 29: 1207-1215.
30. Bayomi M.A. Aqueous preparation and evaluation of albumin-chitosan microspheres containing indomethacin, Drug Dev. Ind. Pharm., 2004, 30: 329-339.
31. Yoshioka T., Hashida M., Muranishi S., Sezaki H. Specific delivery of mitomycin C to the liver, spleen and lung: nano- and microspherical carriers of gelatin, Int. J. Pharm., 1981, 81: 131-141.
32. Wang N., Wu X.S. Preparation and characterization of agarose hydrogel nanoparticles for protein and peptide drug delivery, Pharm. Dev. Technol., 1997, 2: 135-142.
33. Li J.K., Wang N., Wu X.S. A novel biodegradable system based on gelatin nanoparticles and poly(lactic-co-glycolic acid) microspheres for protein and peptide drug delivery, J. Pharm. Sci., 1997, 86: 891-895.
34. Ezpeleta I., Irache J.M., Gueguen J., Orecchioni A.M. Properties of glutaraldehyde cross-linked vicilin nano- and microparticles, J. Microencapsul., 1997, 14: 557-565.
35. Anais J.P., Razzouq N., Carvalho M., Fernandez C., Astier A., Paul M., Astier A., Fessi H., Lorino A.M. Development of alpha-tocopherol acetate nanoparticles: influence of preparative processes, Drug Dev. Ind. Pharm., 2009, 35: 216-223.
36. Jalil R., Nixon J.R. Biodegradable poly(lactic acid) and poly(lactide-co-glycolide) microcapsules: problems associated with preparative techniques and release properties, J. Microencapsul., 1990, 7: 325
37. Wu X.S., in Encyclopedic handbook of biomaterials and bioengineering, D.L.Wise Ed.; Marcel Dekker, New York.1995, 1200
38. Arshady R. Preparation of biodegradable microspheres and microcapsules: 2. Polylactides and related polyesters, J. Control Release, 1991, 17: 1-22.
39. Hrkach J.S., Peracchia M.T., Domb A., Lotan N., Langer R. Nanotechnology for biomaterials engineering: structural characterization of amphiphilic polymeric nanoparticles by 1H NMR spectroscopy, Biomaterials, 1997, 18: 27-30.
40. Mu L., Feng S.S. PLGA/TPGS nanoparticles for controlled release of paclitaxel: effects of the emulsifier and drug loading ratio, Pharm. Res., 2003, 20: 1864-1872.
41. Rosca I.D., Watari F., Uo M. Microparticle formation and its mechanism in single and double emulsion solvent evaporation, J. Control Release, 2004, 99: 271-280.
42. Choi S.H., Park T.G. G-CSF loaded biodegradable PLGA nanoparticles prepared by a single oil-in-water emulsion method, Int. J. Pharm., 2006, 311: 223-228.
43. Pillai R.R., Somayaji S.N., Rabinovich M., Hudson M.C., Gonsalves K.E. Nafcillin-loaded PLGA nanoparticles for treatment of osteomyelitis, Biomed. Mater., 2008, 3: 034114
44. Mei L., Sun H., Jin X., Zhu D., Sun R., Zhang M., Song C. Modified paclitaxel-loaded nanoparticles for inhibition of hyperplasia in a rabbit arterial balloon injury model, Pharm. Res., 2007, 24: 955-962.
45. Adibkia K., Omidi Y., Siahi M.R., Javadzadeh A.R., Barzegar-Jalali M., Barar J., Maleki N., Mohammadi G., Nokhodchi A. Inhibition of endotoxin-induced uveitis by methylprednisolone acetate nanosuspension in rabbits, J. Ocul. Pharmacol. Ther., 2007, 23: 421-432.
46. Adibkia K., Siahi Shadbad M.R., Nokhodchi A., Javadzedeh A., Barzegar-Jalali M., Barar J., Mohammadi G., Omidi Y. Piroxicam nanoparticles for ocular delivery: physicochemical characterization and implementation in endotoxin-induced uveitis, J. Drug Target, 2007, 15: 407-416.
47. Yuan H., Jiang S.P., Du Y.Z., Miao J., Zhang X.G., Hu F.Q. Strategic approaches for improving entrapment of hydrophilic peptide drugs by lipid nanoparticles, Colloids Surf. B Biointerfaces., 2009, 70: 248-253.
48. Dillen K., Bridts C., van d., V, Cos P., Vandervoort J., Augustyns K., Stevens W., Ludwig A. Adhesion of PLGA or Eudragit((R))/PLGA nanoparticles to Staphylococcus and Pseudomonas, Int. J. Pharm., 2008, 349: 234-240.
49. Li X., Xu Y., Chen G., Wei P., Ping Q. PLGA Nanoparticles for the Oral Delivery of 5-Fluorouracil Using High Pressure Homogenization-Emulsification as the Preparation Method and In Vitro/In Vivo Studies, Drug Dev. Ind. Pharm., 2008, 34: 107-115.
50. Eley J.G., Mathew P. Preparation and release characteristics of insulin and insulin-like growth factor-one from polymer nanoparticles, J. Microencapsul., 2007, 24: 225-234.
51. Gvili K., Benny O., Danino D., Machluf M. Poly(D,L-lactide-co-glycolide acid) nanoparticles for DNA delivery: waiving preparation complexity and increasing efficiency, Biopolymers, 2007, 85: 379-391.
52. Dillen K., Vandervoort J., Van den M.G., Ludwig A. Evaluation of ciprofloxacin-loaded Eudragit® RS100 or RL100/PLGA nanoparticles, Int. J. Pharm., 2006, 314: 72-82.
53. Sarmento B., Martins S., Ferreira D., Souto E.B. Oral insulin delivery by means of solid lipid nanoparticles, Int. J. Nanomedicine., 2007, 2: 743-749.
54. Hsu S.H., Kao Y.C. Biocompatibility of poly(carbonate urethane)s with various degrees of nanophase separation, Macromol. Biosci., 2005, 5: 246-253.
55. Gan Q., Wang T. Chitosan nanoparticle as protein delivery carrier - systematic examination of fabrication conditions for efficient loading and release, Colloids Surf. B Biointerfaces., 2007, 59: 24-34.
56. Huang M., Vitharana S.N., Peek L.J., Coop T., Berkland C. Polyelectrolyte complexes stabilize and controllably release vascular endothelial growth factor, Biomacromolecules., 2007, 8: 1607-1614.
57. Boyoglu S., Vig K., Pillai S., Rangari V., Dennis V.A., Khazi F., Singh S.R. Enhanced Delivery and Expression of a Nanoencapsulated DNA Vaccine Vector for RSV, Nanomedicine., 2009,
58. Jain R.A. The manufacturing techniques of various drug loaded biodegradable poly(lactide-co-glycolide) (PLGA) devices, Biomaterials, 2000, 21: 2475-2490.
59. Hore M.J., Laradji M. Microphase separation induced by interfacial segregation of isotropic, spherical nanoparticles, J. Chem. Phys., 2007, 126: 244903
60. Fessi H., Puisieux F., Davissaguet J.Ph., Ammoury N., Benita S. Nanocapsule formation by interfacial polymer deposition following solvent displacement, Int. J. Pharm., 1989, 55: R1-R4
61. Hyvonen S., Peltonen L., Karjalainen M., Hirvonen J. Effect of nanoprecipitation on the physicochemical properties of low molecular weight poly(L-lactic acid) nanoparticles loaded with salbutamol sulphate and beclomethasone dipropionate, Int. J. Pharm., 2005, 295: 269-281.
62. Pignatello R., Amico D., Chiechio S., Spadaro C., Puglisi G., Giunchedi P. Preparation and analgesic activity of Eudragit RS100 microparticles containing diflunisal, Drug Deliv., 2001, 8: 35-45.
63. Pignatello R., Bucolo C., Ferrara P., Maltese A., Puleo A., Puglisi G. Eudragit RS100 nanosuspensions for the ophthalmic controlled delivery of ibuprofen, Eur. J. Pharm. Sci., 2002, 16: 53-61.
64. Pignatello R., Bucolo C., Spedalieri G., Maltese A., Puglisi G. Flurbiprofen-loaded acrylate polymer nanosuspensions for ophthalmic application, Biomaterials, 2002, 23: 3247-3255.
65. Pignatello R., Ricupero N., Bucolo C., Maugeri F., Maltese A., Puglisi G. Preparation and characterization of eudragit retard nanosuspensions for the ocular delivery of cloricromene, AAPS. PharmSciTech., 2006, 7: E27
66. Zhang X., Pan W., Gan L., Zhu C., Gan Y., Nie S. Preparation of a dispersible PEGylate nanostructured lipid carriers (NLC) loaded with 10-hydroxycamptothecin by spray-drying, Chem. Pharm. Bull. (Tokyo), 2008, 56: 1645-1650.
67. Iskandar F., Gradon L., Okuyama K. Control of the morphology of nanostructured particles prepared by the spray drying of a nanoparticle sol, J. Colloid Interface Sci., 2003, 265: 296-303.
68. Varia J.K., Dodiya S.S., Sawant K.K. Cyclosporine a loaded solid lipid nanoparticles: optimization of formulation, process variable and characterization, Curr. Drug Deliv., 2008, 5: 64-69.
69. Eerikainen H., Kauppinen E.I., Kansikas J. Polymeric drug nanoparticles prepared by an aerosol flow reactor method, Pharm. Res., 2004, 21: 136-143.
70. Byrappa K., Ohara S., Adschiri T. Nanoparticles synthesis using supercritical fluid technology - towards biomedical applications, Adv. Drug Deliv. Rev., 2008, 60: 299-327.
71. Castrillo P.D., Olmos D., Amador D.R., Gonzalez-Benito J. Real dispersion of isolated fumed silica nanoparticles in highly filled PMMA prepared by high energy ball milling, J. Colloid Interface Sci., 2007, 308: 318-324.
72. Krause K., Muller R.H. Production and characterization of highly concentrated nanosuspensions by high pressure homogenization, Int. J. Pharm., 2001, 214: 21-24.
73. Douroumis D., Fahr A. Nano- and micro-particulate formulations of poorly water-soluble drugs by using a novel optimized technique, Eur. J. Pharm. Biopharm., 2006, 63: 173-175.
74. Cheng K., Lim L.Y. Insulin-loaded calcium pectinate nanoparticles: effects of pectin molecular weight and formulation pH, Drug Dev. Ind. Pharm., 2004, 30: 359-367.
75. Konan Y.N., Cerny R., Favet J., Berton M., Gurny R., Allemann E. Preparation and characterization of sterile sub-200 nm meso-tetra(4- hydroxylphenyl)porphyrin-loaded nanoparticles for photodynamic therapy, Eur. J. Pharm. Biopharm., 2003, 55: 115-124.