Sex differences in brain anatomy

Progress in Brain Research

Volumn 186, Issue C, 2010, Pages 2-12

  Luders, Eileen ^a   Toga, Arthur W ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Brain; Cortex; Gender; MRI; Sex

Indexed keywords

AUTOPSY; BOOK; BRAIN; BRAIN REGION; BRAIN SIZE; GRAY MATTER; HUMAN; NEUROANATOMY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; SEX DIFFERENCE;

EID: 78649282849     PISSN: 00796123     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-444-53630-3.00001-4     Document Type: Chapter

References (96)

1. Aboitiz F., Scheibel A.B., Fisher R.S., Zaidel E. Fiber composition of the human corpus callosum. Brain Research 1992, 598:143-153.
2. Allen J.S., Damasio H., Grabowski T.J., Bruss J., Zhang W. Sexual dimorphism and asymmetries in the gray-white composition of the human cerebrum. NeuroImage 2003, 18:880-894.
3. Allen L.S., Gorski R.A. Sexual dimorphism of the anterior commissure and massa intermedia of the human brain. The Journal of Comparative Neurology 1991, 312:97-104.
4. Allen L.S., Hines M., Shryne J.E., Gorski R.A. Two sexually dimorphic cell groups in the human brain. Journal of Neuroscience 1989, 9:497-506.
5. Amunts K., Jancke L., Mohlberg H., Steinmetz H., Zilles K. Interhemispheric asymmetry of the human motor cortex related to handedness and gender. Neuropsychologia 2000, 38:304-312.
6. Ankney C.D. The brain size/IQ debate. Nature 1992, 360:292.
7. Arnold A.P. Sex chromosomes and brain gender. Nature Reviews. Neuroscience 2004, 5:701-708.
8. Arnold A.P. Mouse models for evaluating sex chromosome effects that cause sex differences in non-gonadal tissues. Journal of Neuroendocrinology 2009, 21:377-386.
9. Arnold A.P., Gorski R.A. Gonadal steroid induction of structural sex differences in the central nervous system. Annual Review of Neuroscience 1984, 7:413-442.
10. Bear D., Schiff D., Saver J., Greenberg M., Freeman R. Quantitative analysis of cerebral asymmetries. Fronto-Occipital correlation, sexual dimorphism and association with handedness. Archives of Neurology 1986, 43:598-603.
11. Bishop K.M., Wahlsten D. Sex differences in the human corpus callosum: Myth or reality?. Neuroscience and Biobehavioral Reviews 1997, 21:581-601.
12. Blanton R.E., Levitt J.G., Thompson P.M., Narr K.L., Capetillo-Cunliffe L., Nobel A., et al. Mapping cortical asymmetry and complexity patterns in normal children. Psychiatry Research 2001, 107:29-43.
13. Blatter D.D., Bigler E.D., Gale S.D., Johnson S.C., Anderson C.V., Burnett B.M., et al. Quantitative volumetric analysis of brain MR: Normative database spanning 5 decades of life. AJNR. American Journal of Neuroradiology 1995, 16:241-251.
14. Boyke J., Driemeyer J., Gaser C., Buchel C., May A. Training-induced brain structure changes in the elderly. Journal of Neuroscience 2008, 28:7031-7035.
15. Breedlove S.M. Sexual differentiation of the human nervous system. Annual Review of Psychology 1994, 45:389-418.
16. Clarke J.M., Zaidel E. Anatomical-behavioral relationships: Corpus callosum morphometry and hemispheric specialization. Behavioural Brain Research 1994, 64:185-202.
17. Clarke S., Kraftsik R., Van der L.H., Innocenti G.M. Forms and measures of adult and developing human corpus callosum: Is there sexual dimorphism?. The Journal of Comparative Neurology 1989, 280:213-230.
18. Cosgrove K.P., Mazure C.M., Staley J.K. Evolving knowledge of sex differences in brain structure, function, and chemistry. Biological Psychiatry 2007, 62:847-855.
19. Davatzikos C., Resnick S.M. Sex differences in anatomic measures of interhemispheric connectivity: Correlations with cognition in women but not men. Cerebral Cortex 1998, 8:635-640.
20. de Courten-Myers G.M. The human cerebral cortex: Gender differences in structure and function. Journal of Neuropathology and Experimental Neurology 1999, 58:217-226.
21. DeLacoste-Utamsing C., Holloway R.L. Sexual dimorphism in the human corpus callosum. Science 1982, 216:1431-1432.
22. Dekaban A.S. Changes in brain weights during the span of human life: Relation of brain weights to body heights and body weights. Annals of Neurology 1978, 4:345-356.
23. Diamond M.C. Response of the brain to enrichment. Anais da Academia Brasileira de Ciĉncias 2001, 73:211-220.
24. Do Carmo M.P. Differential geometry of curves and surfaces 1976, Englewood Cliffs, Prentice Hall, NJ.
25. Draganski B., Gaser C., Busch V., Schuierer G., Bogdahn U., May A. Neuroplasticity: Changes in grey matter induced by training. Nature 2004, 427:311-312.
26. Draganski B., Gaser C., Kempermann G., Kuhn H.G., Winkler J., Buchel C., et al. Temporal and spatial dynamics of brain structure changes during extensive learning. Journal of Neuroscience 2006, 26:6314-6317.
27. Driemeyer J., Boyke J., Gaser C., Buchel C., May A. Changes in gray matter induced by learning-revisited. PLoS One 2008, 3:e2669.
28. Fernandez-Guasti A., Kruijver F.P., Fodor M., Swaab D.F. Sex differences in the distribution of androgen receptors in the human hypothalamus. The Journal of Comparative Neurology 2000, 425:422-435.
29. Filipek P.A., Richelme C., Kennedy D.N., Caviness V.S. The young adult human brain: An MRI-based morphometric analysis. Cerebral Cortex 1994, 4:344-360.
30. Forget H., Cohen H. Life after birth: The influence of steroid hormones on cerebral structure and function is not fixed prenatally. Brain and Cognition 1994, 26:243-248.
31. Foundas A.L., Faulhaber J.R., Kulynych J.J., Browning C.A., Weinberger D.R. Hemispheric and sex-linked differences in Sylvian fissure morphology: A quantitative approach using volumetric magnetic resonance imaging. Neuropsychiatry, Neuropsychology, and Behavioral Neurology 1999, 12:1-10.
32. Frederikse M.E., Lu A., Aylward E., Barta P., Pearlson G. Sex differences in the inferior parietal lobule. Cerebral Cortex 1999, 9:896-901.
33. Gaser C., Schlaug G. Brain structures differ between musicians and non-musicians. Journal of Neuroscience 2003, 23:9240-9245.
34. Giedd J.N., Blumenthal J., Jeffries N.O., Rajapakse J.C., Vaituzis A.C., Liu H., et al. Development of the human corpus callosum during childhood and adolescence: A longitudinal MRI study. Progress in Neuro-Psychopharmacology & Biological Psychiatry 1999, 23:571-588.
35. Gilmore J.H., Lin W., Prastawa M.W., Looney C.B., Vetsa Y.S., Knickmeyer R.C., et al. Regional gray matter growth, sexual dimorphism, and cerebral asymmetry in the neonatal brain. Journal of Neuroscience 2007, 27:1255-1260.
36. Goldstein J.M., Seidman L.J., Horton N.J., Makris N., Kennedy D.N., Caviness V.S., et al. Normal sexual dimorphism of the adult human brain assessed by in vivo magnetic resonance imaging. Cerebral Cortex 2001, 11:490-497.
37. Good C.D., Johnsrude I., Ashburner J., Henson R.N., Friston K.J., Frackowiak R.S. Cerebral asymmetry and the effects of sex and handedness on brain structure: A voxel-based morphometric analysis of 465 normal adult human brains. NeuroImage 2001, 14:685-700.
38. Gur R.C., Turetsky B.I., Matsui M., Yan M., Bilker W., Hughett P., et al. Sex differences in brain gray and white matter in healthy young adults: Correlations with cognitive performance. Journal of Neuroscience 1999, 19:4065-4072.
39. Harasty J., Double K.L., Halliday G.M., Kril J.J., McRitchie D.A. Language-associated cortical regions are proportionally larger in the female brain. Archives of Neurology 1997, 54:171-176.
40. Highley J.R., Esiri M.M., McDonald B., Roberts H.C., Walker M.A., Crow T.J. The size and fiber composition of the anterior commissure with respect to gender and schizophrenia. Biological Psychiatry 1999, 45:1120-1127.
41. Holloway R.L., de Lacoste M.C. Sexual dimorphism in the human corpus callosum: An extension and replication study. Human Neurobiology 1986, 5:87-91.
42. Ide A., Rodriguez E., Zaidel E., Aboitiz F. Bifurcation patterns in the human Sylvian fissure: Hemispheric and sex differences. Cerebral Cortex 1996, 6:717-725.
43. Im K., Lee J.M., Lee J., Shin Y.W., Kim I.Y., Kwon J.S., et al. Gender difference analysis of cortical thickness in healthy young adults with surface-based methods. Neuroimage 2006, 31:31-38.
44. Jacobs B., Schall M., Scheibel A.B. A quantitative dendritic analysis of Wernicke's area in humans. II. Gender, hemispheric, and environmental factors. The Journal of Comparative Neurology 1993, 327:97-111.
45. Jancke L., Schlaug G., Huang Y., Steinmetz H. Asymmetry of the planum parietale. Neuroreport 1994, 5:1161-1163.
46. Juraska J.M., Fitch J.M., Henderson C., Rivers N. Sex differences in the dendritic branching of dentate granule cells following differential experience. Brain Research 1985, 333:73-80.
47. Kawata M. Roles of steroid hormones and their receptors in structural organization in the nervous system. Neuroscience Research 1995, 24:1-46.
48. Kempermann G., Gast D., Gage F.H. Neuroplasticity in old age: Sustained fivefold induction of hippocampal neurogenesis by long-term environmental enrichment. Annals of Neurology 2002, 52:135-143.
49. Konradi C., Kornhuber J., Sofic E., Heckers S., Riederer P., Beckmann H. Variations of monoamines and their metabolites in the human brain putamen. Brain Research 1992, 579:285-290.
50. Koscik T., O'Leary D., Moser D.J., Andreasen N.C., Nopoulos P. Sex differences in parietal lobe morphology: Relationship to mental rotation performance. Brain and Cognition 2008, 69(3):451-459.
51. Kulynych J.J., Vladar K., Jones D.W., Weinberger D.R. Gender differences in the normal lateralization of the supratemporal cortex: MRI surface-rendering morphometry of Heschl's gyrus and the planum temporale. Cerebral Cortex 1994, 4:107-118.
52. Lee D.J., Chen Y., Schlaug G. Corpus callosum: Musician and gender effects. Neuroreport 2003, 14:205-209.
53. Leonard C.M., Towler S., Welcome S., Halderman L.K., Otto R., Eckert M.A., et al. Size matters: Cerebral volume influences sex differences in neuroanatomy. Cerebral Cortex 2008, 18:2920-2931.
54. Luders E., Gaser C., Jancke L., Schlaug G. A voxel-based approach to gray matter asymmetries. Neuroimage 2004, 22:656-664.
55. Luders E., Gaser C., Narr K.L., Toga A.W. Why sex matters: Brain size independent differences in gray matter distributions between men and women. Journal of Neuroscience 2009, 29:14265-14270.
56. Luders E., Narr K.L., Thompson P.M., Rex D.E., Jancke L., Steinmetz H., et al. Gender differences in cortical complexity. Nature Neuroscience 2004, 7:799-800.
57. Luders E., Narr K.L., Thompson P.M., Rex D.E., Woods R.P., DeLuca H., et al. Gender effects on cortical thickness and the influence of scaling. Human Brain Mapping 2006, 27:314-324.
58. Luders E., Narr K.L., Thompson P.M., Woods R.P., Rex D.E., Jancke L., et al. Mapping cortical gray matter in the young adult brain: Effects of gender. Neuroimage 2005, 26:493-501.
59. Luders E., Narr K.L., Zaidel E., Thompson P.M., Jancke L., Toga A.W. Parasagittal asymmetries of the corpus callosum. Cerebral Cortex 2005, 16(3):347-354.
60. Luders E., Narr K.L., Zaidel E., Thompson P.M., Toga A.W. Gender effects on callosal thickness in scaled and unscaled space. Neuroreport 2006, 17:1103-1106.
61. Luders E., Rex D.E., Narr K.L., Woods R.P., Jancke L., Thompson P.M., et al. Relationships between sulcal asymmetries and corpus callosum size: Gender and handedness effects. Cerebral Cortex 2003, 13:1084-1093.
62. Luders E., Steinmetz H., Jancke L. Brain size and grey matter volume in the healthy human brain. Neuroreport 2002, 13:2371-2374.
63. Luders E., Thompson P.M., Narr K.L., Toga A.W., Jancke L., Gaser C. A curvature-based approach to estimate local gyrification on the cortical surface. Neuroimage 2006, 29:1224-1230.
64. Luders E., Toga A.W., Lepore N., Gaser C. The underlying anatomical correlates of long-term meditation: Larger hippocampal and frontal volumes of gray matter. Neuroimage 2009, 45:672-678.
65. Lyttelton O.C., Karama S., Ad-Dab'bagh Y., Zatorre R.J., Carbonell F., Worsley K., et al. Positional and surface area asymmetry of the human cerebral cortex. Neuroimage 2009, 46:895-903.
66. Maguire E.A., Gadian D.G., Johnsrude I.S., Good C.D., Ashburner J., Frackowiak R.S., et al. Navigation-related structural change in the hippocampi of taxi drivers. Proceedings of the National Academy of Sciences of the United States of America 2000, 97:4398-4403.
67. May A., Hajak G., Ganssbauer S., Steffens T., Langguth B., Kleinjung T., et al. Structural brain alterations following 5 days of intervention: Dynamic aspects of neuroplasticity. Cerebral Cortex 2007, 17:205-210.
68. Mechelli A., Crinion J.T., Noppeney U., O'Doherty J., Ashburner J., Frackowiak R.S., et al. Neurolinguistics: Structural plasticity in the bilingual brain. Nature 2004, 431:757.
69. Ng W.H., Chan Y.L., Au K.S., Yeung K.W., Kwan T.F., To C.Y. Morphometry of the corpus callosum in chinese children: Relationship with gender and academic performance. Pediatric Radiology 2005, 35:565-571.
70. Nopoulos P., Flaum M., O'Leary D., Andreasen N.C. Sexual dimorphism in the human brain: Evaluation of tissue volume, tissue composition and surface anatomy using magnetic resonance imaging. Psychiatry Research 2000, 98:1-13.
71. Pakkenberg B., Gundersen H.J. Neocortical neuron number in humans: Effect of sex and age. The Journal of Comparative Neurology 1997, 384:312-320.
72. Passe T.J., Rajagopalan P., Tupler L.A., Byrum C.E., MacFall J.R., Krishnan K.R. Age and sex effects on brain morphology. Progress in Neuro-Psychopharmacology & Biological Psychiatry 1997, 21:1231-1237.
73. Paus T., Otaky N., Caramanos Z., MacDonald D., Zijdenbos A., D'Avirro D., et al. In vivo morphometry of the intrasulcal gray matter in the human cingulate, paracingulate, and superior-rostral sulci: Hemispheric asymmetries, gender differences and probability maps. The Journal of Comparative Neurology 1996, 376:664-673.
74. Peters M. Sex differences in human brain size and the general meaning of differences in brain size. Canadian Journal of Psychology 1991, 45:507-522.
75. Rabinowicz T., Dean D.E., Petetot J.M., de Courten-Myers G.M. Gender differences in the human cerebral cortex: More neurons in males; more processes in females. Journal of Child Neurology 1999, 14:98-107.
76. Rabinowicz T., Petetot J.M., Gartside P.S., Sheyn D., Sheyn T., de C.M. Structure of the cerebral cortex in men and women. Journal of Neuropathology and Experimental Neurology 2002, 61:46-57.
77. Salat D.H., Buckner R.L., Snyder A.Z., Greve D.N., Desikan R.S., Busa E., et al. Thinning of the cerebral cortex in aging. Cerebral Cortex 2004, 14:721-730.
78. Schlaepfer T.E., Harris G.J., Tien A.Y., Peng L., Lee S., Pearlson G.D. Structural differences in the cerebral cortex of healthy female and male subjects: A magnetic resonance imaging study. Psychiatry Research 1995, 61:129-135.
79. Shin Y.W., Kim D.J., Ha T.H., Park H.J., Moon W.J., Chung E.C., et al. Sex differences in the human corpus callosum: Diffusion tensor imaging study. Neuroreport 2005, 16:795-798.
80. Sowell E.R., Peterson B.S., Kan E., Woods R.P., Yoshii J., Bansal R., et al. Sex differences in cortical thickness mapped in 176 healthy individuals between 7 and 87 years of age. Cerebral Cortex 2007, 17:1550-1560.
81. Steinmetz H., Jancke L., Kleinschmidt A., Schlaug G., Volkmann J., Huang Y. Sex but no hand difference in the isthmus of the corpus callosum. Neurology 1992, 42:749-752.
82. Steinmetz H., Staiger J.F., Schlaug G., Huang Y., Jancke L. Corpus callosum and brain volume in women and men. Neuroreport 1995, 6:1002-1004.
83. Swaab D.F., Fliers E. A sexually dimorphic nucleus in the human brain. Science 1985, 228:1112-1115.
84. Swaab D.F., Fliers E., Partiman T.S. The suprachiasmatic nucleus of the human brain in relation to sex, age and senile dementia. Brain Research 1985, 342:37-44.
85. Thompson P.M., Schwartz C., Lin R.T., Khan A.A., Toga A.W. Three-dimensional statistical analysis of sulcal variability in the human brain. Journal of Neuroscience 1996, 16:4261-4274.
86. Thompson P.M., Schwartz C., Toga A.W. High-resolution random mesh algorithms for creating a probabilistic 3D surface atlas of the human brain. Neuroimage 1996, 3:19-34.
87. Trachtenberg J.T., Chen B.E., Knott G.W., Feng G., Sanes J.R., Welker E., et al. Long-term in vivo imaging of experience-dependent synaptic plasticity in adult cortex. Nature 2002, 420:788-794.
88. Watkins K.E., Paus T., Lerch J.P., Zijdenbos A., Collins D.L., Neelin P., et al. Structural asymmetries in the human brain: A voxel-based statistical analysis of 142 MRI scans. Cerebral Cortex 2001, 11:868-877.
89. Westerhausen R., Kreuder F., Dos Santos S.S., Walter C., Woerner W., Wittling R.A., et al. Effects of handedness and gender on macro- and microstructure of the corpus callosum and its subregions: A combined high-resolution and diffusion-tensor MRI study. Brain Research. Cognitive Brain Research 2004, 21:418-426.
90. Witelson S.F. Hand and sex differences in the isthmus and genu of the human corpus callosum. A postmortem morphological study. Brain 1989, 112(Pt 3):799-835.
91. Witelson S.F., Glezer I.I., Kigar D.L. Women have greater density of neurons in posterior temporal cortex. Journal of Neuroscience 1995, 15:3418-3428.
92. Witelson S.F., Kigar D.L. Sylvian fissure morphology and asymmetry in men and women: bilateral differences in relation to handedness in men. The Journal of Comparative Neurology 1992, 323:326-340.
93. Yucel M., Stuart G.W., Maruff P., Velakoulis D., Crowe S.F., Savage G., et al. Hemispheric and gender-related differences in the gross morphology of the anterior cingulate/paracingulate cortex in normal volunteers: An MRI morphometric study. Cerebral Cortex 2001, 11:17-25.
94. Zhou J.N., Hofman M.A., Gooren L.J., Swaab D.F. A sex difference in the human brain and its relation to transsexuality. Nature 1995, 378:68-70.
95. Zilles K., Armstrong E., Schleicher A., Kretschmann H.J. The human pattern of gyrification in the cerebral cortex. Anatomy and Embryology 1988, 179:173-179.
96. Zilles K., Dabringhaus A., Geyer S., Amunts K., Qu M., Schleicher A., et al. Structural asymmetries in the human forebrain and the forebrain of non-human primates and rats. Neuroscience and Biobehavioral Reviews 1996, 20:593-605.