The underlying anatomical correlates of long-term meditation: Larger hippocampal and frontal volumes of gray matter

NeuroImage

Volumn 45, Issue 3, 2009, Pages 672-678

  Luders, Eileen ^a   Toga, Arthur W ^a   Lepore, Natasha ^a   Gaser, Christian ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

Hippocampus; MRI; Orbital; Plasticity; Thalamus; VBM

Indexed keywords

ADULT; AGED; ARTICLE; BRAIN REGION; BRAIN SIZE; CONTROLLED STUDY; EMOTIONAL STABILITY; FEMALE; FRONTAL CORTEX; GRAY MATTER; HIPPOCAMPUS; HUMAN; MALE; MEDITATION; MORPHOMETRICS; PRIORITY JOURNAL;

BRAIN; BRAIN MAPPING; HUMANS; MAGNETIC RESONANCE IMAGING; MEDITATION;

EID: 61449177745     PISSN: 10538119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroimage.2008.12.061     Document Type: Article

References (44)

1. Ashburner J., and Friston K.J. Voxel-based morphometry - the methods. Neuroimage 11 (2000) 805-821
2. Ashburner J., and Friston K.J. Unified segmentation. Neuroimage 26 (2005) 839-851
3. Baer R.A. Mindfulness training as a clinical intervention: a conceptual and empirical review. Clin. Psychol. Sci. Pract. 10 (2003) 125-143
4. Boyke J., Driemeyer J., Gaser C., Buchel C., and May A. Training-induced brain structure changes in the elderly. J. Neurosci. 28 (2008) 7031-7035
5. Brown K.W., and Ryan R.M. The benefits of being present: mindfulness and its role in psychological well-being. J. Pers. Soc. Psychol. 84 (2003) 822-848
6. Creswell J.D., Way B.M., Eisenberger N.I., and Lieberman M.D. Neural correlates of dispositional mindfulness during affect labeling. Psychosom. Med. 69 (2007) 560-565
7. Creswell, J.D., Myers, H.F., Cole, S.W., Irwin, M.R., in press. Mindfulness meditation training effects on CD4+ T lymphocytes in HIV-1 infected adults: a small randomized controlled trial. Brain Behav. Immun. (Electronic publication ahead of print).
8. Davidson R.J., Jackson D.C., and Kalin N.H. Emotion, plasticity, context, and regulation: perspectives from affective neuroscience. Psychol. Bull 126 (2000) 890-909
9. DeMartino B., Kumaran D., Seymour B., and Dolan R.J. Frames, biases, and rational decision-making in the human brain. Science 313 (2006) 684-687
10. Diamond M.C. Response of the brain to enrichment. An. Acad. Bras. Cienc. 73 (2001) 211-220
11. Doraiswami P.M., and Xiong C.L. Does meditation enhance cognition and brain longevity?. Ann. N.Y. Acad. Sci. (2007) [Electronic Publication ahead of print]
12. Draganski B., Gaser C., Busch V., Schuierer G., Bogdahn U., and May A. Neuroplasticity: changes in grey matter induced by training. Nature 427 (2004) 311-312
13. Draganski B., Gaser C., Kempermann G., Kuhn H.G., Winkler J., Buchel C., and May A. Temporal and spatial dynamics of brain structure changes during extensive learning. J. Neurosci. 26 (2006) 6314-6317
14. Driemeyer J., Boyke J., Gaser C., Buchel C., and May A. Changes in gray matter induced by learning-revisited. PLoS ONE 3 (2008) e2669
15. Eriksson P.S., Perfilieva E., Bjork-Eriksson T., Alborn A.M., Nordborg C., Peterson D.A., and Gage F.H. Neurogenesis in the adult human hippocampus. Nat. Med. 4 (1998) 1313-1317
16. Gage F.H. Neurogenesis in the adult brain. J. Neurosci. 22 (2002) 612-613
17. Gaser C., and Schlaug G. Brain structures differ between musicians and non-musicians. J. Neurosci. 23 (2003) 9240-9245
18. Grossman P., Niemann L., Schmidt S., and Walach H. Mindfulness-based stress reduction and health benefits. A meta-analysis. J. Psychosom. Res. 57 (2004) 35-43
19. Holzel B.K., Ott U., Hempel H., Hackl A., Wolf K., Stark R., and Vaitl D. Differential engagement of anterior cingulate and adjacent medial frontal cortex in adept meditators and non-meditators. Neurosci. Lett. 421 (2007) 16-21
20. Holzel B.K., Ott U., Gard T., Hempel H., Weygandt M., Morgen K., and Vaitl D. Investigation of mindfulness meditation practitioners with voxel-based morphometry. Scan 3 (2008) 55-61
21. Jha A.P., Krompinger J., and Baime M.J. Mindfulness training modifies subsystems of attention. Cogn. Affect. Behav. Neurosci. 7 (2007) 109-119
22. Kempermann G., Gast D., and Gage F.H. Neuroplasticity in old age: sustained fivefold induction of hippocampal neurogenesis by long-term environmental enrichment. Ann. Neurol. 52 (2002) 135-143
23. Lazar S.W., Bush G., Gollub R.L., Fricchione G.L., Khalsa G., and Benson H. Functional brain mapping of the relaxation response and meditation. Neuroreport 11 (2000) 1581-1585
24. Lazar S.W., Kerr C.E., Wasserman R.H., Gray J.R., Greve D.N., Treadway M.T., McGarvey M., Quinn B.T., Dusek J.A., Benson H., Rauch S.L., Moore C.I., and Fischl B. Meditation experience is associated with increased cortical thickness. Neuroreport 16 (2005) 1893-1897
25. Lou H.C., Kjaer T.W., Friberg L., Wildschiodtz G., Holm S., and Nowak M. A 15O-H2O PET study of meditation and the resting state of normal consciousness. Hum. Brain Mapp. 7 (1999) 98-105
26. Lutz A., Brefczynski-Lewis J., Johnstone T., and Davidson R.J. Regulation of the neural circuitry of emotion by compassion meditation: effects of meditative expertise. PloS ONE 3 (2008) e1897
27. Maguire E.A., Gadian D.G., Johnsrude I.S., Good C.D., Ashburner J., Frackowiak R.S., and Frith C.D. Navigation-related structural change in the hippocampi of taxi drivers. Proc. Natl. Acad. Sci. U. S. A. 97 (2000) 4398-4403
28. May A., Hajak G., Ganssbauer S., Steffens T., Langguth B., Kleinjung T., and Eichhammer P. Structural brain alterations following 5 days of intervention: dynamic aspects of neuroplasticity. Cereb. Cortex 17 (2007) 205-210
29. Mechelli A., Crinion J.T., Noppeney U., O'Doherty J., Ashburner J., Frackowiak R.S., and Price C.J. Neurolinguistics: structural plasticity in the bilingual brain. Nature 431 (2004) 757
30. Narr K.L., Bilder R.M., Toga A.W., Woods R.P., Rex D.E., Szeszko P.R., Robinson D., Sevy S., Gunduz-Bruce H., Wang Y.P., DeLuca H., and Thompson P.M. Mapping cortical thickness and gray matter concentration in first episode schizophrenia. Cereb. Cortex 15 (2005) 708-719
31. Newberg A.B., and Iversen J. The neural basis of the complex mental task of meditation: neurotransmitter and neurochemical considerations. Med. Hypotheses 61 (2003) 282-291
32. Newberg A., Alavi A., Baime M., Pourdehnad M., Santanna J., and d'Aquili E. The measurement of regional cerebral blood flow during the complex cognitive task of meditation: a preliminary SPECT study. Psychiatry Res. 106 (2001) 113-122
33. Pagnoni G., and Cekic M. Age effects on gray matter volume and attentional performance in Zen meditation. Neurobiol. Aging 28 (2007) 1623-1627
34. Quirk G.J., and Beer J.S. Prefrontal involvement in the regulation of emotion: convergence of rat and human studies. Curr. Opin. Neurobiol. 16 (2006) 723-727
35. Shattuck D.W., Sandor-Leahy S.R., Schaper K.A., Rottenberg D.A., and Leahy R.M. Magnetic resonance image tissue classification using a partial volume model. Neuroimage 13 (2001) 856-876
36. Smith S.M. Fast robust automated brain extraction. Hum. Brain Mapp. 17 (2002) 143-155
37. So K.T., and Orme-Johnson D.W. Three randomized experiments on the longitudinal effects of the Transcendental Meditation technique on cognition. Intelligence 29 (2001) 419-440
38. Solberg E.E., Ekeberg O., Holen A., Ingjer F., Sandvik L., Standal P.A., and Vikman A. Hemodynamic changes during long meditation. Appl. Psychophysiol. Biofeedback 29 (2004) 213-221
39. Sowell E.R., Peterson B.S., Thompson P.M., Welcome S.E., Henkenius A.L., and Toga A.W. Mapping cortical change across the human life span. Nat. Neurosci. 6 (2003) 309-315
40. Srinivasan N., and Baijal S. Concentrative meditation enhances preattentive processing: a mismatch negativity study. Neuroreport 18 (2007) 1709-1712
41. Tu Z., Narr K.L., Dollar P., Dinov I., Thompson P.M., and Toga A.W. Brain anatomical structure segmentation by hybrid discriminative/generative models. IEEE Trans. Med. Imag. 27 (2008) 495-508
42. Tversky A., and Kahneman D. The framing of decisions and the psychology of choice. Science 211 (1981) 453-458
43. Vestergaard-Poulsen P., van B.M., Skewes J., Bjarkam C.R., Stubberup M., Bertelsen J., and Roepstorff A. Long-term meditation is associated with increased gray matter density in the brain stem. Neuroreport 20 2 (2009) 170-174
44. Woods R.P., Grafton S.T., Watson J.D., Sicotte N.L., and Mazziotta J.C. Automated image registration: II. Intersubject validation of linear and nonlinear models. J. Comput. Assist. Tomogr. 22 (1998) 153-165