Humanization strategies for an anti-idiotypic antibody mimicking HIV-1 gp41

Protein Engineering, Design and Selection

Volumn 23, Issue 12, 2010, Pages 947-954

  Mader, A ^a   Kunert, R ^a  

^a UNIVERSITY OF AGRICULTURAL SCIENCES   (Austria)

Author keywords

2F5; anti idiotyp; HIV 1; humanization; vaccine

Indexed keywords

2F5; ANTI-IDIOTYP; ANTI-IDIOTYPIC ANTIBODIES; ANTIGEN RECOGNITION; BINDING ABILITIES; BINDING AFFINITIES; BINDING PROPERTIES; CLINICAL TRAILS; COMPLEMENTARITY-DETERMINING REGIONS; HIV-1; HUMANIZATION; IMMUNOGENICITY; THERAPEUTIC PROTEIN;

BINDING ENERGY; GRAFTING (CHEMICAL); MONOCLONAL ANTIBODIES; VACCINES;

DISEASES;

ANTIIDIOTYPIC ANTIBODY; GLYCOPROTEIN GP 41;

ANTIBODY AFFINITY; ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; CHIMERA; COMPLEMENTARITY DETERMINING REGION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; MOUSE; NONHUMAN; PRIORITY JOURNAL;

AIDS VACCINES; AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, ANTI-IDIOTYPIC; ANTIBODIES, MONOCLONAL; BIOMIMETIC MATERIALS; COMPLEMENTARITY DETERMINING REGIONS; HIV ENVELOPE PROTEIN GP41; HUMANS; IMMUNOGLOBULIN HEAVY CHAINS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; PROTEIN ENGINEERING; SEQUENCE ALIGNMENT; SINGLE-CHAIN ANTIBODIES;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 78649272270     PISSN: 17410126     EISSN: 17410134     Source Type: Journal    
DOI: 10.1093/protein/gzq092     Document Type: Article

References (54)

1. Adams, C., Allison, D., Flagella, K., Presta, L., Clarke, J., Dybdal, N., McKeever, K. and Sliwkowski, M. (2006) Cancer Immunol. Immunother., 55, 717-727.
2. Almagro, J. and Fransson, J. (2008)Front. Biosci., 13, 1619-1633.
3. Amanna, I., Messaoudi, I. and Slifka, M. (2008) Hum. Vaccin., 4, 316-319.
4. Baker D. and Sali, A. (2001) Science 294: 93-96. doi: 10.1126/science.1065659.
5. Bruccoleri, R. and Karplus, M. (1987) Biopolymers, 26, 137-168.
6. Burton, D., Desrosiers, R., Doms, R., et al. (2004) Nat. Immunol., 5, 233-236. doi: 10.1038/ni0304-233.
7. Caldas, C., Coelho, V., Rigden, D., Neschich, G., Moro, A. and Bŕigido, M. (2000) Protein Eng., 13, 353-360.
8. Cardoso, R., Zwick, M., Stanfield, R., Kunert, R., Binley, J., Katinger, H., Burton, D. and Wilson, I. (2005) Immunity, 22, 163-173. doi: 10.1016/j.immuni.2004.12.011.
9. Carter, P., Presta, L., Gorman, C., et al. (1992) Proc. Natl Acad. Sci. USA, 89, 4285-4289.
10. Chothia, C. and Lesk, A. (1987) J. Mol. Biol., 196, 901-917.
11. Chothia, C., Lesk, A., Tramontano, A., et al. (1989) Nature, 342, 877-883.
12. Co, M., Deschamps, M., Whitley, R. and Queen, C. (1991) Proc. Natl Acad. Sci. USA, 88, 2869-2873.
13. Dauber-Osguthorpe, P., Roberts, V., Osguthorpe, D., Wolff, J., Genest, M. and Hagler, A. (1988) Proteins, 4, 31-47.
14. Fields, B., Goldbaum, F., Ysern, X., Poljak, R. and Mariuzza, R. (1995) Nature, 374, 739-742. doi: 10.1038/374739a0.
15. Flynn, N., Forthal, D., Harro, C., Judson, F, Mayer, K. and Para, M. and Group r.H.V.S. (2005) J. Infect. Dis., 191, 654-665. doi: 10.1086/428404.
16. Foote, J. and Winter, G. (1992) J. Mol. Biol., 224, 487-499.
17. Gach, J., Quendler, H., Weik, R., Katinger, H. and Kunert, R. (2007) AIDS Res. Hum. Retroviruses, 23, 1405-1415.
18. Gonzales, N., Padlan, E., De Pascalis, R., Schuck, P., Schlom, J. and Kashmiri, S. (2003) Mol. Immunol., 40, 337-349. doi: S0161589003001664.
19. Guex, N. and Peitsch, M. (1997) Electrophoresis, 18, 2714-2723.
20. Haynes, B. and Montefiori, D. (2006) Expert Rev. Vaccines, 5, 579-595. doi: 10.1586/14760584.5.4.579.
21. Hu, W., Chau, D., Wu, J., Jager, S. and Nagata, L. (2007) Vaccine, 25, 3210-3214.
22. Hurvitz, S. and Timmerman, J. (2005) Curr. Opin. Oncol., 17, 432-440. doi: 00001622-200509000-00003.
23. Hwang, W. and Foote, J. (2005) Methods, 36, 3-10. doi: 10.1016/j.ymeth.2005.01.001.
24. Hwang, W., Almagro, J., Buss, T., Tan, P. and Foote, J. (2005) Methods, 36, 35-42.
25. Inogès, S., Rodr̀iguez-Calvillo, M., Zabalegui, N., et al. (2006) J. Natl Cancer Inst., 98, 1292-1301. doi: 10.1093/jnci/djj358.
26. Jerne, N. (1974)Ann. Immunol. (Paris), 125C, 373-389.
27. Jerne, N., Roland, J. and Cazenave, P. (1982) EMBO J., 1, 243-247.
28. Jones, P., Dear, P., Foote, J., Neuberger, M. and Winter, G. (1986) Nature, 321, 522-525.
29. Kunert, R., Steinfellner, W., Purtscher, M., Assadian, A. and Katinger, H. (2000) Biotechnol. Bioeng., 67, 97-103.
30. Kunert, R., Weik, R., Ferko, B., Stiegler, G. and Katinger, H. (2002) AIDS, 16, 667-668.
31. Maiorov, V. and Crippen, G. (1994) J. Mol. Biol., 235, 625-634. doi: 10.1006/jmbi.1994.1017.
32. Mian, I., Bradwell, A. and Olson, A. (1991) J. Mol. Biol., 217, 133-151.
33. Novotný, J., Handschumacher, M., Haber, E., Bruccoleri, R., Carlson, W., Fanning, D., Smith, J. and Rose, G. (1986) Proc. Natl Acad. Sci. USA, 83, 226-230.
34. Ofek, G., Tang, M., Sambor, A., Katinger, H., Mascola, J., Wyatt, R. and Kwong, P. (2004) J. Virol., 78, 10724-10737. doi: 10.1128/JVI.78.19.10724-10737. 2004.
35. Park, I., Youn, J., Choi, I., Nahm, M., Kim, S. and Shin, J. (2005) Infect. Immun., 73, 6399-6406. doi: 10.1128/IAI.73.10.6399-6406.2005.
36. Pedersen, J., Henry, A., Searle, S., Guild, B., Roguska, M. and Rees, A. (1994) J. Mol. Biol., 235, 959-973.
37. Plotkin, S. (2008) Clin. Infect. Dis., 47, 401-409. doi: 10.1086/589862.
38. Presta, L., Lahr, S., Shields, R., Porter, J., Gorman, C., Fendly, B. and Jardieu, P. (1993) J. Immunol., 151, 2623-2632.
39. Purtscher, M., Trkola, A., Gruber, G., et al. (1994) AIDS Res. Hum. Retroviruses, 10, 1651-1658.
40. Queen, C., Schneider, W., Selick, H., et al. (1989) Proc. Natl Acad. Sci. USA, 86, 10029-10033.
41. Rerks-Ngarm, S., Pitisuttithum, P., Nitayaphan, S., et al. (2009) N. Engl. J. Med., 361, 2209-2220. doi: 10.1056/NEJMoa0908492.
42. Riechmann, L., Clark, M., Waldmann, H. and Winter, G. (1988) Nature, 332, 323-327.
43. Rodon, J., Garrison, M., Hammond, L., et al. (2008) Cancer Chemother. Pharmacol., 62, 911-919. doi: 10.1007/s00280-007-0672-8.
44. Roguska, M., Pedersen, J., Keddy, C., et al. (1994) Proc. Natl Acad. Sci. USA, 91, 969-973.
45. Rosok, M., Yelton, D., Harris, L., et al. (1996) J. Biol. Chem., 271, 22611-22618.
46. Sgro, C. (1995) Toxicology, 105, 23-29. doi: 0300483X9503123W.
47. Shoenfeld, Y. (1995) Clin. Exp. Immunol., 101(Suppl. 1), 26-28.
48. Staelens, S., Desmet, J., Ngo, T., et al. (2006) Mol. Immunol., 43, 1243-1257.
49. Stoiber, H., Frank, I., Spruth, M., et al. (1997) Mol. Immunol., 34, 855-863.
50. Tan, P., Mitchell, D., Buss, T., Holmes, M., Anasetti, C. and Foote, J. (2002) J. Immunol., 169, 1119-1125.
51. Trkola, A., Pomales, A., Yuan, H., et al. (1995) J. Virol., 69, 6609-6617.
52. Urlaub, G. and Chasin, L. (1980) Proc. Natl Acad. Sci. USA, 77, 4216-4220.
53. Van Gunsteren, W.F, Billeter, S.R., Eising, A.A., Huenenberger, P.H., Krueger, P., Mark, A.E., Scott, W.R.P. and Tiron, I.G. (1996) Biomolecular Simulation: The GROMOS96 Manual and User Guide, VdF: Hochschulverlag AG, Zuerich, Switzerland.
54. Whitelegg, N. and Rees, A. (2000) Protein Eng., 13, 819-824.