Inhibition of HIV-1 infection in vitro by monoclonal antibodies to the complement receptor type 3 (CR3): An accessory role for CR3 during virus entry?

Molecular Immunology

Volumn 34, Issue 12-13, 1997, Pages 855-863

  Stoiber, Heribert ^a,e   Frank, Ines ^a   Spruth, Martin ^a   Schwendinger, Michael ^a   Mullauer, Brigitte ^a   Windisch, Jörg M ^b   Schneider, Rainer ^b   Katinger, Hermann ^c   Ando, Istvan ^d   Dierich, Manfred P ^a,f  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^b UNIVERSITY OF INNSBRUCK   (Austria)

^c UNIVERSITY OF NATURAL RESOURCES AND LIFE SCIENCES   (Austria)

^d INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^e UNIVERSITY OF LIVERPOOL   (United Kingdom)

^f Inst fur Hygiene und Sozialmedizin   (Austria)

Author keywords

Adhesion molecule; CR3; gp41; HIV

Indexed keywords

CD11B ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; GLYCOPROTEIN GP 41; INTEGRIN; INTERCELLULAR ADHESION MOLECULE 1; MONOCLONAL ANTIBODY; PHORBOL 13 ACETATE 12 MYRISTATE; POLYCLONAL ANTIBODY; VIRUS GLYCOPROTEIN;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLUORESCENCE ACTIVATED CELL SORTER; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LIGAND BINDING; MONONUCLEAR CELL; NONHUMAN; PRIORITY JOURNAL; ROSETTE FORMATION; VIRUS CELL INTERACTION; VIRUS INFECTION; VIRUS INHIBITION;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; OVIS ARIES;

EID: 0031414824     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0161-5890(97)00108-9     Document Type: Article

References (47)

1. Alkhatib G., Combadiere C., Broder C. C., Feng Y., Kennedy P. E., Murphy P. M. and Berger E. A. (1996) CC CKR5: a RANTES, MIPl-alpha, MIPl-beta receptor as a fusin cofactor for macrophage-tropic HIV. Science 272, 1955-1958.
2. Andersson E. C., Christensen J. P., Marker O. and Thomsen A. R. (1994) Changes in cell adhesion molecules expression on T cells associated with systemic virus infection. J. Immun. 152, 1237-1245.
3. Arnaout A. (1990) Structure and function of the leucocyte adhesion molecules CD11/CD18. Blood 75, 1037-1050.
4. Arthur L. O., Bess J. W., Sowder R. C., Benveniste R. E., Mann D. L., Chermann C.-J. and Henderson L. E. (1992) Cellular proteins bound to immunodeficiency viruses: implications for pathogenesis and vaccines. Science 258, 1935-1938.
5. Chomczynski P. and Sacchi N. (1987) Single step method of RNA isolation by acid guanidium thiocyanate phenolchloroform extraction. Analyt. Biochem. 162, 156-159.
6. Clerici M. and Shearer G. M. (1993) A TH1 → TH2 switch is a critical step in the etiology of HIV infection. Immun. Today 14, 107-111.
7. Dalgleish A. G., Beverley P. C. L., Clapham P. R., Crawford D. H., Greaves M. F. and Weiss R. A. (1984) The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus. Nature 312, 763-767.
8. Dedera D. and Gu R., Ratner L. (1992) Role of asperagine linked glycosylation in human immunodeficiency virus type 1 transmembrane envelope function. Virology 187, 377-382.
9. Deng H., Liu R., Ellmeier W., Choc S., Unutmaz D., Burkhart M., DiMazio P., Marmon S., Sutton R. E., Hill C. M., Davis C. B., Peiper C., Schall T. J., Littman D. R. and Landau N. R. (1996) Identifcation of a major co-receptor for primary isolates of HIV-1. Nature 381, 661-666.
10. Diamond M. S., Garcia-Aguilar J., Bickford J. K., Corbi A. L. and Springer T. A. J. (1993) The I domain is a major recognition site on leucocyte integrin Mac-1 (CD1lb/CD18) for four distinct adhesion ligands. Cell Biol. 120, 1031-1043.
11. Dimitrov D. S., Broder C. C., Berger E. A. and Blumenthal R. (1993) Calcium ions are required for cell fusion mediated by the CD4-human immunodeficiency virus type 1 envelope glycoprotein interaction. J. Virol. 67, 1647-1652.
12. Doranz B. J., Rucker J., Yi Y., Smyth R. J., Samson M.,Peiper C., Parmentier M., Collman R. G. and Doms R. W. (1996) A dual-tropic HIV primary-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors. Cell 85, 1149-1158.
13. Ebenbichler C., Thielens N., Arlaud G. and Dierich M. P. (1991) Human immunodeficiency virus type 1 activates the classical pathway of complement by direct Cl binding through specific sites in the transmembrane glycoprotein gp41. J. exp. Med. 174, 1417-1424.
14. Ebenbichler C. F., Stoiber H., Schneider R., Patsch J. R. and Dierich M. P. (1996) The human immunodeficiency virus type 1 transmembrane gp41 protein is a calcium-binding protein and interacts with the putative second-receptor molecules in a calcium-dependent manner. J. Virol. 70, 1723-1728.
15. Feng Y., Broder C. C., Kennedy P. E. and Berger E. A. (1996) HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor. Science 272, 872-877.
16. Frank I., Stoiber H., Godar S., Stockinger H., Steindl F., Katinger H. W. and Dierich M. P. (1996) Acquisition of host cell-surface-derived molecules by HIV-1. AIDS 10, 1611-1620.
17. Frey S., Marsh M., Gunther S., Pelchen-Matthews A., Stephen P., Ortlepp S. and Stegmann T. (1995) Temperature dependence of cell-cell fusion induced by the envelope glycoprotein of human immunodeficiency virus type 1. J. Virol. 69, 1462-1472.
18. Fu Y. K., Hart T. K., Jonak Z. L. and Bugelski P. J. (1993) Physiochemical dissociation of CD4-mediated syncytium formation and shedding of human immunodeficiency virus type 1 gp120. J. Virol. 67, 3818-3825.
19. Gomez M. B. and Hildreth J. E. K. (1995) Antibodies of adhesion molecule LFA-1 enhances plasma neutralization of human immunodeficiency virus type 1. J. Virol. 69, 4628-4632.
20. Hildreth J. E. K. and Orentas R. J. (1989) Involvment of a leukocyte adhesion receptor (LFA-1) in HIV-induced syscytium formation. Science 244, 1075-1078.
21. Kalter D. C., Gendelman H. E. and Meltzer M. S. (1991) Inhibition of human immunodeficiency virus infection in monocytes by monoclonal antibodies against leukocyte adhesion molecules. Immun. Lett. 30, 219-228.
22. Klatzmann D., Champagne E., Chamaret S., Gruest J., Guetard D., Hercend T., Gluckman J.-C. and Montagnier L. (1984) T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV. Nature 312, 767-768.
23. Kowalski M., Potz J., Basiripour L., Dorfman T., Goh C. W., Terwilliger E., Dayton A., Rosen C., Haseltine W. and Sodroski J. (1987) Functional regions of the envelope glycoprotein of human immunodeficency virus type 1. Science 237, 1351-1355
24. Lambris J. D. (1990) The Third Component of Complement. Springer-Verlag, Berlin.
25. Marth T. and Kelsall B. (1997) Regulation of interleukin-12 by complement receptor 3 signaling. J. exp. Med. 185, 1987-1995.
26. Messika E. J., Avni O., Gallily R., Yefenof E. and Barniyash M. (1995) Identification and characterization of a novel protein associated with macrophage complement receptor 3. J. Immun. 154, 6563-6570.
27. Nielsen H. V., Christensen J. P., Andersson E. C., Marker O. and Thomsen A. R. (1994) Expression of type 3 complement receptor on activated CD8+ T cells facilitates homing to inflammatory sites. J. Immun. 153, 2021-2028.
28. Orentas R. J. and Hildreth J. E. K. (1993) Association of host cell surface adhesion receptors and other membrane proteins with HIV and SIV. AIDS Res. Hum. Retroviruses 9, 1157-1164.
29. Palmer S. and Hamblin A. S. (1993) Increased CD11/CD18 expression on the peripheral blood leucocytes of patients with HIV disease: relationship to disease severity. Clin. exp. Immun. 93, 344-349.
30. Pantaleo G., Butini L., Graziosi C., Poli G., Schnittman S. M., Greenhouse J. J., Gallin J. I. and Fauci A. S. (1991) Human immunodeficiency virus (HIV) infection in CD4+ T lymphocytes genetically deficient in LFA-1: LFA-1 is required for HIV-mediated cell fusion but not for viral transmission. J. exp. Med. 173, 511-514.
31. Purtscher M., Trkola A., Gruber G., Buchacher A., Predl R., Steindl F., Tauer C., Berger R., Barrett N., Jungbauer A. and Katinger H. (1995) A broadly neutralizing human monoclonal antibody against gp41 of human immunodeficiency virus type 1. AIDS Res. Hum. Retroviruses 10, 1651-1658.
32. Rizzuto C. D. and Sodroski J. G. (1997) Contribution of virion ICAM-1 to human immunodeficiency virus infectivity and sensitivity to neutralization. J. Virol. 71, 4847-4851.
33. Sattentau Q. J. and Moore J. P. (1991) Conformational changes induced in the human immunodeficiency virus envelope glycoprotein by soluble CD4 binding. J. exp. Med. 174, 407-415.
34. Springer T. A. (1990) Adhesion receptors of the immune system. Nature 346, 425-431.
35. Stöckl J., Majdic O., Pickl W. F., Rosenkranz A., Prager E., Gschwantler E., Knapp W. (1995) Granulocyte activation via a binding site near the C-terminal region of complement receptor type 3 α-chain (CD11b) potentially involved in intramembrane complex formation with glycosylphosphatidylinositol-anchored Fc γRIIIB (CD16) molecules. J. Immun. 154, 5452-5463.
36. Stoiber H., Ebenbichler C., Schneider R., Janatova J. and Dierich M. P. (1995) Interaction of several complement proteins with gp120 and gp41, the two envelope glycoproteins of HIV-1. AIDS 9, 19-26.
37. Stoiber H., Ebenbichler C., Schneider R., Janatova J. and Dierich M. P. (1995) Human complement proteins C3b, C4b, factor H and properdin react with specific sites in gp120 and gp4l, the envelope proteins of HIV-1. Immunobiology 193, 98-113.
38. Stoiber H., Ebenbichler C. F., Thielens N. M., Arlaud G. J. and Dierich M. P. (1995) HIV I rsgp41 depends on calcium for binding of human Clq but not for binding of gp120. Molec. Immun. 32, 371-374.
39. Stoiber H., Pintér C., Siccardi A. G., Clivio A. and Dierich M. P. (1996) Efficient destruction of HIV in human serum by inhibiting the protective action of complement factor H and decay accelerating factor (DAF, CD55). J. exp. Med. 183, 307-310.
40. Stoiber H., Clivio A. and Dierich M. P. (1997) Role of complement in HIV infection. Annu. Rev. Immun. 15, 649-674.
41. Thieblemont N., Haeffner-Cavaillon N., Haeffner A., Cholley B., Weiss L., Kazatchkine M. D. (1995) Triggering of complement receptors CR1 (CD35) and CR3 (CD11b/CD18) induces nuclear translocation of NF-kappa B (p50/p65) in human monocytcs and enhances viral replication in HIV-infected monocytic cells. J. Immun. 155, 4861-4867.
42. Thielens N., Bally I. M., Ebenbichler C., Dierich M. P. and Arlaud G. (1993) Further characterization of the interaction between the Clq subcomponent of human C1 and the transmembrane envelope glycoprotein gp41 of HIV-1. J. Immun. 151, 6583-6592
43. Uciechowski P. and Schmidt H. (1989) Cluster report: CD11. In Leucocyte Typing IV: White Cell Differantiation Antigens (Edited by Knapp W., Dorken B., Gilks W., et al.), pp. 543-551. Oxford University Press, Oxford.
44. Vornhagen R., Hinderer W. and Nebel-Schnickel H. (1990) Development of efficient HIV-specific test system using recombinant viral antigens. Biotest Bull. 4, 91-99.
45. Weis J. J., Fearon D. T., Klickstein L. B., Wong W. W., Richards S. A., de Bruyn Kops A., Smith J. A., Weis J. H. (1986) Identification of a partial cDNA clone for the C3d/Epstein-Barr virus receptor of human B lymphocytes: homology with the receptor for fragments C3b and C4b of the third and fourth components of complement. Proc. natn. Acad. Sci. U.S.A. 83, 5639-5643.
46. Wild C., Oas T., Bolognesi D. and Matthews T. (1992) A synthetic peptide inhibitor of human immunodeficiency virus replication: correlation between solution and viral inhibition. Proc. natn. Acad. Sci. U.S.A. 89, 10537-10541.
47. Wild C., Greenwell T., Shugars D., Rimsky-Clark L. and Matthews T. (1995) The inhibitory activity of an HIV type 1 peptide correlates with its ability to interact with a leucine zipper structure. AIDS Res. Hum. Retroviruses 11, 323-325.