SMT-A07, a 3-(Indol-2-yl) indazole derivative, induces apoptosis of leukemia cells in vitro

Molecular and Cellular Biochemistry

Volumn 345, Issue 1-2, 2010, Pages 13-21

  Qian, Shijing ^a   Cao, Ji ^a   Yan, Yan ^a   Sun, Maotang ^b   Zhu, Hong ^a   Hu, Yongzhou ^b   He, Qiaojun ^a   Yang, Bo ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY   (China)

Author keywords

Apoptosis; Caspases; Leukemia; SMT A07

Indexed keywords

ANTINEOPLASTIC AGENT; INDAZOLE DERIVATIVE; N [2 (1H INDAZOL 3 YL) 1H PYRROLO[3,2 B] PYRIDIN 5 YL] 4 CHLORO N METHYLBENZAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROCASPASE 3; PROCASPASE 8; PROTEIN BID; SMT A07; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CYTOTOXICITY; DNA FRAGMENTATION; DOWN REGULATION; DRUG STRUCTURE; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IC 50; LEUKEMIA CELL; UPREGULATION;

APOPTOSIS; BENZAMIDES; CASPASES; CELL LINE, TUMOR; DNA FRAGMENTATION; HL-60 CELLS; HUMANS; INDAZOLES; INHIBITORY CONCENTRATION 50; LEUKEMIA;

EID: 78449314063     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-010-0554-y     Document Type: Article

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