Sequence-dependent prion protein misfolding and neurotoxicity

Journal of Biological Chemistry

Volumn 285, Issue 47, 2010, Pages 36897-36908

  Fernandez Funez, Pedro ^a   Zhang, Yan ^a   Casas Tinto, Sergio ^b   Xiao, Xiangzhu ^c   Zou, Wen Quan ^c   Rincon Limas, Diego E ^a  

^a UNIVERSITY OF FLORIDA   (United States)

^b Structural Biology and Biocomputing Programme   (Spain)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID SEQUENCE; CONFORMATIONAL CHANGE; CONFORMATIONAL DYNAMICS; MAMMALIAN PRION PROTEINS; MISFOLDING; MOLECULAR MECHANISM; NEURODEGENERATION; NEURODEGENERATIVE DISORDERS; NEUROTOXICITY; PRION DISEASE; PRION PROTEIN; SEQUENCE-DEPENDENT; TRANSGENICS;

AMINO ACIDS; MAMMALS;

PROTEINS;

PRION PROTEIN;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DEGENERATIVE DISEASE; DROSOPHILA; LOCOMOTION; MOLECULAR MECHANICS; MOTOR DYSFUNCTION; MOUSE; NEUROTOXICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRION DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN LOCALIZATION; RABBIT; SCRAPIE; SYRIAN HAMSTER; TRANSGENIC ANIMAL;

AMINO ACID SEQUENCE; ANIMALS; ANIMALS, GENETICALLY MODIFIED; BLOTTING, WESTERN; CHROMATOGRAPHY, GEL; CONSERVED SEQUENCE; CRICETINAE; DROSOPHILA MELANOGASTER; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; IMMUNOPRECIPITATION; LOCOMOTION; MALE; MICE; MOLECULAR SEQUENCE DATA; NEUROTOXICITY SYNDROMES; PRION DISEASES; PRIONS; PROTEIN CONFORMATION; PROTEIN FOLDING; RABBITS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SEQUENCE HOMOLOGY, AMINO ACID;

CRICETINAE; MAMMALIA; MAMMALIAN PRION; ORYCTOLAGUS CUNICULUS;

EID: 78449260181     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.174391     Document Type: Article

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