Arsenic trioxide (As2O3) inhibits peritoneal invasion of ovarian carcinoma cells in vitro and in vivo

Gynecologic Oncology

Volumn 103, Issue 1, 2006, Pages 199-206

  Zhang, Jingjing ^a   Wang, Bo ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

Arsenic trioxide; Metastasis; Ovarian neoplasms; Peritoneum

Indexed keywords

ARSENIC TRIOXIDE; BETA ACTIN; GELATINASE A; GELATINASE B; RNA; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2;

ARTICLE; CANCER CELL; CANCER INVASION; CELL ADHESION; CELL MIGRATION; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; GENE EXPRESSION; HUMAN; HUMAN CELL; METASTASIS; OVARY CARCINOMA; PERITONEUM CANCER; PERITONEUM METASTASIS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANTINEOPLASTIC AGENTS; ARSENICALS; CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; NEOPLASM INVASIVENESS; OVARIAN NEOPLASMS; OXIDES; PERITONEAL NEOPLASMS; RNA, MESSENGER; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TISSUE INHIBITOR OF METALLOPROTEINASE-2;

EID: 33748537775     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2006.02.037     Document Type: Article

References (30)

1. Gallagher R.E. Arsenic: new life for an old potion. N. Engl. J. Med. 339 (1998) 1389-1391
2. 3. Int. J. Mol. Med. 9 (2002) 385-390
3. Uslu R., Sanli U.A., Sezgin C., Karabulut B., Terzioglu E., Omay S.B., et al. Arsenic trioxide-mediated cytotoxicity and apoptosis in prostate and ovarian carcinoma cell lines. Clin. Cancer Res. 6 (2000) 4957-4964
4. Mizutani K., Kofuji K., and Shirouzu K. The significance of MMP-1 and MMP-2 in peritoneal disseminated metastasis of gastric cancer. Surg. Today 30 (2000) 612-621
5. Van Rossen M.E., Hofland L.J., van den Tol M.P., van Koetsveld P.M., Jeekel J., Marquet R.L., et al. Effect of inflammatory cytokines and growth factors on tumor cell adhesion to the peritoneum. J. Pathol. 193 (2001) 530-537
6. Hirashima Y., Kobayashi H., Suzuki M., Tanaka Y., Kanayama N., and Terao T. Transforming growth factor-β1 produced by ovarian cancer cell line HRA stimulates attachment and invasion through an up-regulation of plasminogen activator inhibitor type-1 in human peritoneal mesothelial cells. J. Biol. Chem. 278 (2003) 26793-26802
7. 3) inhibits invasion of HT1080 human fibrosarcoma cells: role of nuclear factor-κB and reactive oxygen species. J. Cell. Biochem. 95 (2005) 955-969
8. Hsu M.Y., Meier F.E., Nesbit M., Hsu J.Y., Van Belle P., Elder D.E., et al. E-cadherin expression in melanoma cells restores keratinocyte-mediated growth control and down-regulates expression of invasion-related adhesion receptors. Am. J. Pathol. 156 (2000) 1515-1525
9. Davidson B., Gotlieb W.H., Ben-Baruch G., Nesland J.M., Bryne M., Goldberg I., et al. E-cadherin complex protein expression and survival in ovarian carcinoma. Gynecol. Oncol. 79 (2000) 362-371
10. Lessan K., Aguiar D.J., Oegama T., Siebenson L., and Skubitz A.P. CD44 and β1 integrin mediate ovarian carcinoma cell adhesion to peritoneal mesothelial cells. Am. J. Pathol. 154 (1999) 1525-1537
11. Liu T.F., Cheng B.L., Guan Y.G., and Liang T. Study on relationship between expressions of CD44 and inhibition effect of arsenic trioxide on carcinoma. J. Harbin Med. Univ. 35 (2001) 111-112
12. Wells A. Tumor invasion: role of growth factor-induced cell motility. Adv. Cancer Res. 78 (2000) 31-101
13. Hayot C., Farinelle S., De Decker R., Decaestecker C., Darro F., Kiss R., et al. In vitro pharmacological characterization of the anti-angiogenic and anti-tumor cell migration properties mediated by mirotubule-affecting drugs, with special emphasis on the organization of the actin cytoskeleton. Int. J. Oncol. 21 (2002) 417-425
14. Li Y.M., and Broome J.D. Arsenic targets tubulins to induce apoptosis in myeloid leukemia cells. Cancer Res. 59 (1999) 776-780
15. Stamenkovic I. Matrix metalloproteinases in tumor invasion and metastasis. Semin. Cancer Biol. 10 (2000) 415-433
16. Fan Y.Z., Zhang J.T., Yang H.C., and Yang Y.Q. Expression of MMP-2, TIMP-2 protein and the ratio of MMP-2/TIMP-2 in gallbladder carcinoma and their significance. World J. Gastroenterol. 8 (2002) 1138-1143
17. Zucher S., Cao J., and Chen W.T. Critical appraisal of the use of the matrix metalloproteinase inhibitors in cancer treatment. Oncogene 19 (2000) 6642-6650
18. Stetler-Stevenson W.G., Brown P.D., Onisto M., Levy A.T., and Liotta L.A. Tissue inhibitor of metalloproteinases-2 (TIMP-2) mRNA expression in tumor cell lines and human tumor tissues. J. Biol. Chem. 265 (1990) 13933-13938
19. Shapiro S.D., Kobayashi D.K., and Welgus H.G. Identification of TIMP-2 in human alveolar macrophages. Regulation of biosynthesis is opposite to that of metalloproteinases and TIMP-1. J. Biol. Chem. 267 (1992) 13890-13894
20. Zafarullah M., Su S., Martel-Pelletier J., DiBattista J.A., Costello B.G., Stetler-Stevenson W.G., et al. Tissue inhibitor of metalloproteinase-2 (TIMP-2) mRNA is constitutively expressed in bovine, human normal, and osteoarthritic articular chondrocytes. J. Cell. Biochem. 60 (1996) 211-217
21. Hammani K., Blakis A., Morsette D., Bowcock A.M., Schmutte C., Henriet P., et al. Structure and characterization of the human tissue inhibitor of metalloproteinases-2 gene. J. Biol. Chem. 271 (1996) 25498-25505
22. Kim H., and Koh G. Lipopolysaccharide activates matrix metalloproteinase-2 in endothelial cells through an NF-kappaB-dependent pathway. Biochem. Biophys. Res. Commun. 269 (2000) 401-405
23. 2 activates pro-matrix metalloproteinase-2 through receptor tyrosine kinases/phosphatidylinositol 3-kinase/NF-kappaB pathway. J. Biol. Chem. 277 (2002) 30271-30282
24. Miller Jr. W.H., Schipper H.M., Lee J.S., Singer J., and Waxman S. Mechanisms of action of arsenic trioxide. Cancer Res. 62 (2002) 3893-3903
25. Liu Q., Hilsenbeck S., and Gazitt Y. Arsenic trioxide-induced apoptosis in myeloma cells: p53-dependent G1 or G2/M cell cycle arrest, activation of caspase-8 or caspase-9, and synergy with APO2/TRAIL. Blood 101 (2003) 4078-4087
26. Kreppel H., Reichl F.X., Szinicz L., Fichtl B., and Forth W. Efficacy of various dithiol compounds in acute As2O3 poisoning in mice. Arch. Toxicol. 64 (1990) 387-392
27. 3 on transplanting ovarian cancer in the normal immunity mouse. China J. Mod. Med. 13 (2003) 18-22
28. Huang S.G., Kong B.H., Yang R.F., and Jiang S. Primary study of arsenic trioxide inhibits abdomino-metastatic tumor formation of human ovarian carcinoma in nude mice and its mechanisms. Ai Zheng 21 (2002) 401-404
29. Wei L.H., Lai K.P., Chen C.A., Cheng C.H., Huang Y.J., Chou C.H., et al. Arsenic trioxide prevents radiation-enhanced tumor invasiveness and inhibits matrix metalloproteinase-9 through downregulation of nuclear factor kappaB. Oncogene 243 (2005) 390-398
30. 3 on ascites production in nude mice with colorectal cancer. Chin. J. Dig. 19 (1999) 378-380