메뉴 건너뛰기




Volumn 41, Issue 1, 2011, Pages 147-159

The fragile X mental retardation protein developmentally regulates the strength and fidelity of calcium signaling in Drosophila mushroom body neurons

Author keywords

Autism; Calcium buffering proteins; Cognitive impairment; Fragile X syndrome; Learning; Memory; MRNA; Synapse; Translation

Indexed keywords

CALBINDIN; CALCIUM; CALCIUM BINDING PROTEIN; CALMODULIN; FRAGILE X MENTAL RETARDATION PROTEIN; GREEN FLUORESCENT PROTEIN; MESSENGER RNA;

EID: 78349309391     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2010.09.002     Document Type: Article
Times cited : (39)

References (117)
  • 1
    • 65249106110 scopus 로고    scopus 로고
    • Crystal structures of the GCaMP calcium sensor reveal the mechanism of fluorescence signal change and aid rational design
    • Akerboom J., et al. Crystal structures of the GCaMP calcium sensor reveal the mechanism of fluorescence signal change and aid rational design. J. Biol. Chem. 2009, 284:6455-6464.
    • (2009) J. Biol. Chem. , vol.284 , pp. 6455-6464
    • Akerboom, J.1
  • 2
    • 1642336232 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor activation regulates fragile X mental retardation protein and FMR1 mRNA localization differentially in dendrites and at synapses
    • Antar L.N., et al. Metabotropic glutamate receptor activation regulates fragile X mental retardation protein and FMR1 mRNA localization differentially in dendrites and at synapses. J. Neurosci. 2004, 24:2648-2655.
    • (2004) J. Neurosci. , vol.24 , pp. 2648-2655
    • Antar, L.N.1
  • 3
    • 0031710933 scopus 로고    scopus 로고
    • Increased transmitter release and aberrant synapse morphology in a Drosophila calmodulin mutant
    • Arredondo L., et al. Increased transmitter release and aberrant synapse morphology in a Drosophila calmodulin mutant. Genetics 1998, 150:265-274.
    • (1998) Genetics , vol.150 , pp. 265-274
    • Arredondo, L.1
  • 4
    • 13844316424 scopus 로고    scopus 로고
    • The fragile X mental retardation protein and group I metabotropic glutamate receptors regulate levels of mRNA granules in brain
    • Aschrafi A., et al. The fragile X mental retardation protein and group I metabotropic glutamate receptors regulate levels of mRNA granules in brain. Proc. Natl Acad. Sci. USA 2005, 102:2180-2185.
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 2180-2185
    • Aschrafi, A.1
  • 5
    • 73749084118 scopus 로고    scopus 로고
    • Calcium-induced calcium release contributes to synaptic release from mouse rod photoreceptors
    • Babai N., et al. Calcium-induced calcium release contributes to synaptic release from mouse rod photoreceptors. Neuroscience 2009, 165:1447-1456.
    • (2009) Neuroscience , vol.165 , pp. 1447-1456
    • Babai, N.1
  • 6
    • 33748167050 scopus 로고    scopus 로고
    • Compensation of inositol 1,4,5-trisphosphate receptor function by altering sarco-endoplasmic reticulum calcium ATPase activity in the Drosophila flight circuit
    • Banerjee S., et al. Compensation of inositol 1,4,5-trisphosphate receptor function by altering sarco-endoplasmic reticulum calcium ATPase activity in the Drosophila flight circuit. J. Neurosci. 2006, 26:8278-8288.
    • (2006) J. Neurosci. , vol.26 , pp. 8278-8288
    • Banerjee, S.1
  • 7
    • 0038333642 scopus 로고    scopus 로고
    • Calbindin in cerebellar Purkinje cells is a critical determinant of the precision of motor coordination
    • Barski J.J., et al. Calbindin in cerebellar Purkinje cells is a critical determinant of the precision of motor coordination. J. Neurosci. 2003, 23:3469-3477.
    • (2003) J. Neurosci. , vol.23 , pp. 3469-3477
    • Barski, J.J.1
  • 8
    • 3042647610 scopus 로고    scopus 로고
    • The mGluR theory of fragile X mental retardation
    • Bear M.F., et al. The mGluR theory of fragile X mental retardation. Trends Neurosci. 2004, 27:370-377.
    • (2004) Trends Neurosci. , vol.27 , pp. 370-377
    • Bear, M.F.1
  • 9
    • 33748998205 scopus 로고    scopus 로고
    • Fragile X syndrome and autism at the intersection of genetic and neural networks
    • Belmonte M.K., Bourgeron T. Fragile X syndrome and autism at the intersection of genetic and neural networks. Nat. Neurosci. 2006, 9:1221-1225.
    • (2006) Nat. Neurosci. , vol.9 , pp. 1221-1225
    • Belmonte, M.K.1    Bourgeron, T.2
  • 10
    • 0034822840 scopus 로고    scopus 로고
    • Profile of cognitive functioning in women with the fragile X mutation
    • Bennetto L., et al. Profile of cognitive functioning in women with the fragile X mutation. Neuropsychology 2001, 15:290-299.
    • (2001) Neuropsychology , vol.15 , pp. 290-299
    • Bennetto, L.1
  • 11
    • 0034304906 scopus 로고    scopus 로고
    • The versatility and universality of calcium signalling
    • Berridge M.J., et al. The versatility and universality of calcium signalling. Nat. Rev. Mol. Cell Biol. 2000, 1:11-21.
    • (2000) Nat. Rev. Mol. Cell Biol. , vol.1 , pp. 11-21
    • Berridge, M.J.1
  • 12
    • 0031930176 scopus 로고    scopus 로고
    • Overexpression of fragile X gene (FMR-1) transcripts increases cAMP production in neural cells
    • Berry-Kravis E., Ciurlionis R. Overexpression of fragile X gene (FMR-1) transcripts increases cAMP production in neural cells. J. Neurosci. Res. 1998, 51:41-48.
    • (1998) J. Neurosci. Res. , vol.51 , pp. 41-48
    • Berry-Kravis, E.1    Ciurlionis, R.2
  • 13
    • 68849128519 scopus 로고    scopus 로고
    • Short- and long-term memory in Drosophila require cAMP signaling in distinct neuron types
    • Blum A.L., et al. Short- and long-term memory in Drosophila require cAMP signaling in distinct neuron types. Curr. Biol. 2009, 19:1341-1350.
    • (2009) Curr. Biol. , vol.19 , pp. 1341-1350
    • Blum, A.L.1
  • 14
    • 52949109182 scopus 로고    scopus 로고
    • Excess protein synthesis in Drosophila fragile X mutants impairs long-term memory
    • Bolduc F.V., et al. Excess protein synthesis in Drosophila fragile X mutants impairs long-term memory. Nat. Neurosci. 2008, 11:1143-1145.
    • (2008) Nat. Neurosci. , vol.11 , pp. 1143-1145
    • Bolduc, F.V.1
  • 15
    • 45549107222 scopus 로고    scopus 로고
    • Circuit and plasticity defects in the developing somatosensory cortex of FMR1 knock-out mice
    • Bureau I., et al. Circuit and plasticity defects in the developing somatosensory cortex of FMR1 knock-out mice. J. Neurosci. 2008, 28:5178-5188.
    • (2008) J. Neurosci. , vol.28 , pp. 5178-5188
    • Bureau, I.1
  • 16
    • 60849129819 scopus 로고    scopus 로고
    • The Drosophila fragile X mental retardation gene regulates sleep need
    • Bushey D., et al. The Drosophila fragile X mental retardation gene regulates sleep need. J. Neurosci. 2009, 29:1948-1961.
    • (2009) J. Neurosci. , vol.29 , pp. 1948-1961
    • Bushey, D.1
  • 17
    • 77954815485 scopus 로고    scopus 로고
    • Age-dependent cognitive impairment in a Drosophila fragile X model and its pharmacological rescue
    • Choi C.H., et al. Age-dependent cognitive impairment in a Drosophila fragile X model and its pharmacological rescue. Biogerontology 2010, 11:347-362.
    • (2010) Biogerontology , vol.11 , pp. 347-362
    • Choi, C.H.1
  • 18
    • 34147129139 scopus 로고    scopus 로고
    • Autism spectrum phenotype in males and females with fragile X full mutation and premutation
    • Clifford S., et al. Autism spectrum phenotype in males and females with fragile X full mutation and premutation. J. Autism Dev. Disord. 2007, 37:738-747.
    • (2007) J. Autism Dev. Disord. , vol.37 , pp. 738-747
    • Clifford, S.1
  • 19
    • 77954843658 scopus 로고    scopus 로고
    • Fragile X mental retardation protein has a unique, evolutionarily conserved neuronal function not shared with FXR1P or FXR2P
    • Coffee R.L., et al. Fragile X mental retardation protein has a unique, evolutionarily conserved neuronal function not shared with FXR1P or FXR2P. Dis. Model Mech. 2010, 3:471-485.
    • (2010) Dis. Model Mech. , vol.3 , pp. 471-485
    • Coffee, R.L.1
  • 20
    • 21244472348 scopus 로고    scopus 로고
    • Specific genetic disorders and autism: clinical contribution towards their identification
    • Cohen D., et al. Specific genetic disorders and autism: clinical contribution towards their identification. J. Autism Dev. Disord. 2005, 35:103-116.
    • (2005) J. Autism Dev. Disord. , vol.35 , pp. 103-116
    • Cohen, D.1
  • 21
    • 0030986183 scopus 로고    scopus 로고
    • Abnormal dendritic spines in fragile X knockout mice: maturation and pruning deficits
    • Comery T.A., et al. Abnormal dendritic spines in fragile X knockout mice: maturation and pruning deficits. Proc. Natl Acad. Sci. USA 1997, 94:5401-5404.
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 5401-5404
    • Comery, T.A.1
  • 22
    • 3843074360 scopus 로고    scopus 로고
    • Action potential-evoked and ryanodine-sensitive spontaneous Ca2+ transients at the presynaptic terminal of a developing CNS inhibitory synapse
    • Conti R., et al. Action potential-evoked and ryanodine-sensitive spontaneous Ca2+ transients at the presynaptic terminal of a developing CNS inhibitory synapse. J. Neurosci. 2004, 24:6946-6957.
    • (2004) J. Neurosci. , vol.24 , pp. 6946-6957
    • Conti, R.1
  • 23
    • 42449090738 scopus 로고    scopus 로고
    • High speed two-photon imaging of calcium dynamics in dendritic spines: consequences for spine calcium kinetics and buffer capacity
    • Cornelisse L.N., et al. High speed two-photon imaging of calcium dynamics in dendritic spines: consequences for spine calcium kinetics and buffer capacity. PLoS ONE 2007, 2:e1073.
    • (2007) PLoS ONE , vol.2
    • Cornelisse, L.N.1
  • 24
    • 77953528456 scopus 로고    scopus 로고
    • Delayed stabilization of dendritic spines in fragile X mice
    • Cruz-Martin A., et al. Delayed stabilization of dendritic spines in fragile X mice. J. Neurosci. 2010, 30:7793-7803.
    • (2010) J. Neurosci. , vol.30 , pp. 7793-7803
    • Cruz-Martin, A.1
  • 25
    • 33750726094 scopus 로고    scopus 로고
    • Decreased expression of the GABAA receptor in fragile X syndrome
    • D'Hulst C., et al. Decreased expression of the GABAA receptor in fragile X syndrome. Brain Res. 2006, 1121:238-245.
    • (2006) Brain Res. , vol.1121 , pp. 238-245
    • D'Hulst, C.1
  • 26
    • 0035942734 scopus 로고    scopus 로고
    • Disruption of neurotransmission in Drosophila mushroom body blocks retrieval but not acquisition of memory
    • Dubnau J., et al. Disruption of neurotransmission in Drosophila mushroom body blocks retrieval but not acquisition of memory. Nature 2001, 411:476-480.
    • (2001) Nature , vol.411 , pp. 476-480
    • Dubnau, J.1
  • 27
    • 31744434726 scopus 로고    scopus 로고
    • Rapid and simple comparison of messenger RNA levels using real-time PCR
    • Dussault A.A., Pouliot M. Rapid and simple comparison of messenger RNA levels using real-time PCR. Biol. Proced Online 2006, 8:1-10.
    • (2006) Biol. Proced Online , vol.8 , pp. 1-10
    • Dussault, A.A.1    Pouliot, M.2
  • 28
    • 70450195596 scopus 로고    scopus 로고
    • Calcium buffering in rodent olfactory bulb granule cells and mitral cells
    • Egger V., Stroh O. Calcium buffering in rodent olfactory bulb granule cells and mitral cells. J. Physiol. 2009, 587:4467-4479.
    • (2009) J. Physiol. , vol.587 , pp. 4467-4479
    • Egger, V.1    Stroh, O.2
  • 29
    • 67349278796 scopus 로고    scopus 로고
    • Drosophila fragile X protein controls cellular proliferation by regulating cbl levels in the ovary
    • Epstein A.M., et al. Drosophila fragile X protein controls cellular proliferation by regulating cbl levels in the ovary. Dev. Biol. 2009, 330:83-92.
    • (2009) Dev. Biol. , vol.330 , pp. 83-92
    • Epstein, A.M.1
  • 30
    • 0037453129 scopus 로고    scopus 로고
    • In vivo calcium imaging of brain activity in Drosophila by transgenic cameleon expression
    • Fiala A., Spall T. In vivo calcium imaging of brain activity in Drosophila by transgenic cameleon expression. Sci. STKE 2003, PL6.
    • (2003) Sci. STKE
    • Fiala, A.1    Spall, T.2
  • 31
    • 0025974956 scopus 로고
    • Cognitive profiles associated with the fra(X) syndrome in males and females
    • Freund L.S., Reiss A.L. Cognitive profiles associated with the fra(X) syndrome in males and females. Am. J. Med. Genet. 1991, 38:542-547.
    • (1991) Am. J. Med. Genet. , vol.38 , pp. 542-547
    • Freund, L.S.1    Reiss, A.L.2
  • 32
    • 0021358472 scopus 로고
    • The psychological profile of the fragile X syndrome
    • Fryns J.P., et al. The psychological profile of the fragile X syndrome. Clin. Genet. 1984, 25:131-134.
    • (1984) Clin. Genet. , vol.25 , pp. 131-134
    • Fryns, J.P.1
  • 33
    • 9344246891 scopus 로고    scopus 로고
    • Visual experience regulates transient expression and dendritic localization of fragile X mental retardation protein
    • Gabel L.A., et al. Visual experience regulates transient expression and dendritic localization of fragile X mental retardation protein. J. Neurosci. 2004, 24:10579-10583.
    • (2004) J. Neurosci. , vol.24 , pp. 10579-10583
    • Gabel, L.A.1
  • 34
    • 20044388939 scopus 로고    scopus 로고
    • Sequence of abnormal dendritic spine development in primary somatosensory cortex of a mouse model of the fragile X mental retardation syndrome
    • Galvez R., Greenough W.T. Sequence of abnormal dendritic spine development in primary somatosensory cortex of a mouse model of the fragile X mental retardation syndrome. Am. J. Med. Genet. A 2005, 135:155-160.
    • (2005) Am. J. Med. Genet. A , vol.135 , pp. 155-160
    • Galvez, R.1    Greenough, W.T.2
  • 35
    • 20444431185 scopus 로고    scopus 로고
    • Olfactory bulb mitral cell dendritic pruning abnormalities in a mouse model of the fragile-X mental retardation syndrome: further support for FMRP's involvement in dendritic development
    • Galvez R., et al. Olfactory bulb mitral cell dendritic pruning abnormalities in a mouse model of the fragile-X mental retardation syndrome: further support for FMRP's involvement in dendritic development. Brain Res. Dev. Brain Res. 2005, 157:214-216.
    • (2005) Brain Res. Dev. Brain Res. , vol.157 , pp. 214-216
    • Galvez, R.1
  • 36
    • 66149123016 scopus 로고    scopus 로고
    • The fragile X mental retardation protein in circadian rhythmicity and memory consolidation
    • Gatto C.L., Broadie K. The fragile X mental retardation protein in circadian rhythmicity and memory consolidation. Mol. Neurobiol. 2009, 39:107-129.
    • (2009) Mol. Neurobiol. , vol.39 , pp. 107-129
    • Gatto, C.L.1    Broadie, K.2
  • 37
    • 0029955188 scopus 로고    scopus 로고
    • Long-term potentiation in the hippocampus of fragile X knockout mice
    • Godfraind J.M., et al. Long-term potentiation in the hippocampus of fragile X knockout mice. Am. J. Med. Genet. 1996, 64:246-251.
    • (1996) Am. J. Med. Genet. , vol.64 , pp. 246-251
    • Godfraind, J.M.1
  • 38
    • 33746892681 scopus 로고    scopus 로고
    • Hippocampal pyramidal cells in adult Fmr1 knockout mice exhibit an immature-appearing profile of dendritic spines
    • Grossman A.W., et al. Hippocampal pyramidal cells in adult Fmr1 knockout mice exhibit an immature-appearing profile of dendritic spines. Brain Res. 2006, 1084:158-164.
    • (2006) Brain Res. , vol.1084 , pp. 158-164
    • Grossman, A.W.1
  • 39
    • 76849083912 scopus 로고    scopus 로고
    • Origins of epilepsy in fragile x syndrome
    • Hagerman P.J., Stafstrom C.E. Origins of epilepsy in fragile x syndrome. Epilepsy Curr. 2009, 9:108-112.
    • (2009) Epilepsy Curr. , vol.9 , pp. 108-112
    • Hagerman, P.J.1    Stafstrom, C.E.2
  • 40
    • 23944490213 scopus 로고    scopus 로고
    • Recent advances in fragile X: a model for autism and neurodegeneration
    • Hagerman R.J., et al. Recent advances in fragile X: a model for autism and neurodegeneration. Curr. Opin. Psychiatry 2005, 18:490-496.
    • (2005) Curr. Opin. Psychiatry , vol.18 , pp. 490-496
    • Hagerman, R.J.1
  • 41
    • 34247116144 scopus 로고    scopus 로고
    • Presynaptic FMR1 genotype influences the degree of synaptic connectivity in a mosaic mouse model of fragile X syndrome
    • Hanson J.E., Madison D.V. Presynaptic FMR1 genotype influences the degree of synaptic connectivity in a mosaic mouse model of fragile X syndrome. J. Neurosci. 2007, 27:4014-4018.
    • (2007) J. Neurosci. , vol.27 , pp. 4014-4018
    • Hanson, J.E.1    Madison, D.V.2
  • 42
    • 0027338192 scopus 로고
    • Novel Ca2+ channels underlying transduction in Drosophila photoreceptors: implications for phosphoinositide-mediated Ca2+ mobilization
    • Hardie R.C., Minke B. Novel Ca2+ channels underlying transduction in Drosophila photoreceptors: implications for phosphoinositide-mediated Ca2+ mobilization. Trends Neurosci. 1993, 16:371-376.
    • (1993) Trends Neurosci. , vol.16 , pp. 371-376
    • Hardie, R.C.1    Minke, B.2
  • 43
    • 75949119188 scopus 로고    scopus 로고
    • Critical period plasticity is disrupted in the barrel cortex of FMR1 knockout mice
    • Harlow E.G., et al. Critical period plasticity is disrupted in the barrel cortex of FMR1 knockout mice. Neuron 2010, 65:385-398.
    • (2010) Neuron , vol.65 , pp. 385-398
    • Harlow, E.G.1
  • 44
    • 63349086828 scopus 로고    scopus 로고
    • Differences in Ca2+ regulation for high-output Is and low-output Ib motor terminals in Drosophila larvae
    • He T., et al. Differences in Ca2+ regulation for high-output Is and low-output Ib motor terminals in Drosophila larvae. Neuroscience 2009, 159:1283-1291.
    • (2009) Neuroscience , vol.159 , pp. 1283-1291
    • He, T.1
  • 45
    • 84907112220 scopus 로고
    • Drosophila mushroom body mutants are deficient in olfactory learning
    • Heisenberg M., et al. Drosophila mushroom body mutants are deficient in olfactory learning. J. Neurogenet. 1985, 2:1-30.
    • (1985) J. Neurogenet. , vol.2 , pp. 1-30
    • Heisenberg, M.1
  • 46
    • 68549121216 scopus 로고    scopus 로고
    • Functional coupling between mGluR1 and Cav3.1 T-type calcium channels contributes to parallel fiber-induced fast calcium signaling within Purkinje cell dendritic spines
    • Hildebrand M.E., et al. Functional coupling between mGluR1 and Cav3.1 T-type calcium channels contributes to parallel fiber-induced fast calcium signaling within Purkinje cell dendritic spines. J. Neurosci. 2009, 29:9668-9682.
    • (2009) J. Neurosci. , vol.29 , pp. 9668-9682
    • Hildebrand, M.E.1
  • 47
    • 0042568798 scopus 로고    scopus 로고
    • Neuronal calcium sensor-1: a multifunctional regulator of secretion
    • Hilfiker S. Neuronal calcium sensor-1: a multifunctional regulator of secretion. Biochem. Soc. Trans. 2003, 31:828-832.
    • (2003) Biochem. Soc. Trans. , vol.31 , pp. 828-832
    • Hilfiker, S.1
  • 48
    • 33746866693 scopus 로고    scopus 로고
    • Dynamic translational and proteasomal regulation of fragile X mental retardation protein controls mGluR-dependent long-term depression
    • Hou L., et al. Dynamic translational and proteasomal regulation of fragile X mental retardation protein controls mGluR-dependent long-term depression. Neuron 2006, 51:441-454.
    • (2006) Neuron , vol.51 , pp. 441-454
    • Hou, L.1
  • 49
    • 0037188502 scopus 로고    scopus 로고
    • Altered synaptic plasticity in a mouse model of fragile X mental retardation
    • Huber K.M., et al. Altered synaptic plasticity in a mouse model of fragile X mental retardation. Proc. Natl Acad. Sci. USA 2002, 99:7746-7750.
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 7746-7750
    • Huber, K.M.1
  • 50
    • 0037158482 scopus 로고    scopus 로고
    • Dendritic spine and dendritic field characteristics of layer V pyramidal neurons in the visual cortex of fragile-X knockout mice
    • Irwin S.A., et al. Dendritic spine and dendritic field characteristics of layer V pyramidal neurons in the visual cortex of fragile-X knockout mice. Am. J. Med. Genet. 2002, 111:140-146.
    • (2002) Am. J. Med. Genet. , vol.111 , pp. 140-146
    • Irwin, S.A.1
  • 51
    • 21544482277 scopus 로고    scopus 로고
    • Drosophila mushroom body Kenyon cells generate spontaneous calcium transients mediated by PLTX-sensitive calcium channels
    • Jiang S.A., et al. Drosophila mushroom body Kenyon cells generate spontaneous calcium transients mediated by PLTX-sensitive calcium channels. J. Neurophysiol. 2005, 94:491-500.
    • (2005) J. Neurophysiol. , vol.94 , pp. 491-500
    • Jiang, S.A.1
  • 52
    • 4444238669 scopus 로고    scopus 로고
    • Biochemical evidence for the association of fragile X mental retardation protein with brain polyribosomal ribonucleoparticles
    • Khandjian E.W., et al. Biochemical evidence for the association of fragile X mental retardation protein with brain polyribosomal ribonucleoparticles. Proc. Natl Acad. Sci. USA 2004, 101:13357-13362.
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 13357-13362
    • Khandjian, E.W.1
  • 53
    • 23044503253 scopus 로고    scopus 로고
    • Deletion of FMR1 in Purkinje cells enhances parallel fiber LTD, enlarges spines, and attenuates cerebellar eyelid conditioning in fragile X syndrome
    • Koekkoek S.K., et al. Deletion of FMR1 in Purkinje cells enhances parallel fiber LTD, enlarges spines, and attenuates cerebellar eyelid conditioning in fragile X syndrome. Neuron 2005, 47:339-352.
    • (2005) Neuron , vol.47 , pp. 339-352
    • Koekkoek, S.K.1
  • 54
    • 0037130472 scopus 로고    scopus 로고
    • Selective replenishment of two vesicle pools depends on the source of Ca2+ at the Drosophila synapse
    • Kuromi H., Kidokoro Y. Selective replenishment of two vesicle pools depends on the source of Ca2+ at the Drosophila synapse. Neuron 2002, 35:333-343.
    • (2002) Neuron , vol.35 , pp. 333-343
    • Kuromi, H.1    Kidokoro, Y.2
  • 55
    • 0346687601 scopus 로고    scopus 로고
    • Ca2+ influx through distinct routes controls exocytosis and endocytosis at Drosophila presynaptic terminals
    • Kuromi H., et al. Ca2+ influx through distinct routes controls exocytosis and endocytosis at Drosophila presynaptic terminals. Neuron 2004, 41:101-111.
    • (2004) Neuron , vol.41 , pp. 101-111
    • Kuromi, H.1
  • 56
    • 26844565093 scopus 로고    scopus 로고
    • Age-dependent and selective impairment of long-term potentiation in the anterior piriform cortex of mice lacking the fragile X mental retardation protein
    • Larson J., et al. Age-dependent and selective impairment of long-term potentiation in the anterior piriform cortex of mice lacking the fragile X mental retardation protein. J. Neurosci. 2005, 25:9460-9469.
    • (2005) J. Neurosci. , vol.25 , pp. 9460-9469
    • Larson, J.1
  • 57
    • 33751343407 scopus 로고    scopus 로고
    • Ca2+ dynamics along identified synaptic terminals in Drosophila larvae
    • Lnenicka G.A., et al. Ca2+ dynamics along identified synaptic terminals in Drosophila larvae. J. Neurosci. 2006, 26:12283-12293.
    • (2006) J. Neurosci. , vol.26 , pp. 12283-12293
    • Lnenicka, G.A.1
  • 58
    • 67849133734 scopus 로고    scopus 로고
    • Calcium signaling and the development of specific neuronal connections
    • Lohmann C. Calcium signaling and the development of specific neuronal connections. Prog. Brain Res. 2009, 175:443-452.
    • (2009) Prog. Brain Res. , vol.175 , pp. 443-452
    • Lohmann, C.1
  • 59
    • 0033378174 scopus 로고    scopus 로고
    • Mushroom body ablation impairs short-term memory and long-term memory of courtship conditioning in Drosophila melanogaster
    • McBride S.M., et al. Mushroom body ablation impairs short-term memory and long-term memory of courtship conditioning in Drosophila melanogaster. Neuron 1999, 24:967-977.
    • (1999) Neuron , vol.24 , pp. 967-977
    • McBride, S.M.1
  • 60
    • 20044388322 scopus 로고    scopus 로고
    • Pharmacological rescue of synaptic plasticity, courtship behavior, and mushroom body defects in a Drosophila model of fragile X syndrome
    • McBride S.M., et al. Pharmacological rescue of synaptic plasticity, courtship behavior, and mushroom body defects in a Drosophila model of fragile X syndrome. Neuron 2005, 45:753-764.
    • (2005) Neuron , vol.45 , pp. 753-764
    • McBride, S.M.1
  • 61
    • 0035903017 scopus 로고    scopus 로고
    • The role of Drosophila mushroom body signaling in olfactory memory
    • McGuire S.E., et al. The role of Drosophila mushroom body signaling in olfactory memory. Science 2001, 293:1330-1333.
    • (2001) Science , vol.293 , pp. 1330-1333
    • McGuire, S.E.1
  • 62
    • 0031594742 scopus 로고    scopus 로고
    • The endoplasmic reticulum Ca2+ store: a view from the lumen
    • Meldolesi J., Pozzan T. The endoplasmic reticulum Ca2+ store: a view from the lumen. Trends Biochem. Sci. 1998, 23:10-14.
    • (1998) Trends Biochem. Sci. , vol.23 , pp. 10-14
    • Meldolesi, J.1    Pozzan, T.2
  • 63
    • 34248548824 scopus 로고    scopus 로고
    • Increased threshold for spike-timing-dependent plasticity is caused by unreliable calcium signaling in mice lacking fragile X gene FMR1
    • Meredith R.M., et al. Increased threshold for spike-timing-dependent plasticity is caused by unreliable calcium signaling in mice lacking fragile X gene FMR1. Neuron 2007, 54:627-638.
    • (2007) Neuron , vol.54 , pp. 627-638
    • Meredith, R.M.1
  • 64
    • 3042735950 scopus 로고    scopus 로고
    • Defective neuronal development in the mushroom bodies of Drosophila fragile X mental retardation 1 mutants
    • Michel C.I., et al. Defective neuronal development in the mushroom bodies of Drosophila fragile X mental retardation 1 mutants. J. Neurosci. 2004, 24:5798-5809.
    • (2004) J. Neurosci. , vol.24 , pp. 5798-5809
    • Michel, C.I.1
  • 65
    • 34249064936 scopus 로고    scopus 로고
    • Dysregulated metabotropic glutamate receptor-dependent translation of AMPA receptor and postsynaptic density-95 mRNAs at synapses in a mouse model of fragile X syndrome
    • Muddashetty R.S., et al. Dysregulated metabotropic glutamate receptor-dependent translation of AMPA receptor and postsynaptic density-95 mRNAs at synapses in a mouse model of fragile X syndrome. J. Neurosci. 2007, 27:5338-5348.
    • (2007) J. Neurosci. , vol.27 , pp. 5338-5348
    • Muddashetty, R.S.1
  • 66
    • 0035129282 scopus 로고    scopus 로고
    • A high signal-to-noise Ca(2+) probe composed of a single green fluorescent protein
    • Nakai J., et al. A high signal-to-noise Ca(2+) probe composed of a single green fluorescent protein. Nat. Biotechnol. 2001, 19:137-141.
    • (2001) Nat. Biotechnol. , vol.19 , pp. 137-141
    • Nakai, J.1
  • 67
    • 0035879180 scopus 로고    scopus 로고
    • Abnormal development of dendritic spines in FMR1 knock-out mice
    • Nimchinsky E.A., et al. Abnormal development of dendritic spines in FMR1 knock-out mice. J. Neurosci. 2001, 21:5139-5146.
    • (2001) J. Neurosci. , vol.21 , pp. 5139-5146
    • Nimchinsky, E.A.1
  • 68
    • 33646194363 scopus 로고    scopus 로고
    • Metabotropic receptor-dependent long-term depression persists in the absence of protein synthesis in the mouse model of fragile X syndrome
    • Nosyreva E.D., Huber K.M. Metabotropic receptor-dependent long-term depression persists in the absence of protein synthesis in the mouse model of fragile X syndrome. J. Neurophysiol. 2006, 95:3291-3295.
    • (2006) J. Neurophysiol. , vol.95 , pp. 3291-3295
    • Nosyreva, E.D.1    Huber, K.M.2
  • 69
    • 39349103605 scopus 로고    scopus 로고
    • Ultrastructural analysis of chemical synapses and gap junctions between Drosophila brain neurons in culture
    • Oh H.W., et al. Ultrastructural analysis of chemical synapses and gap junctions between Drosophila brain neurons in culture. Dev. Neurobiol. 2008, 68:281-294.
    • (2008) Dev. Neurobiol. , vol.68 , pp. 281-294
    • Oh, H.W.1
  • 70
    • 67649834454 scopus 로고    scopus 로고
    • Increased GABA(B) receptor-mediated signaling reduces the susceptibility of fragile X knockout mice to audiogenic seizures
    • Pacey L.K., et al. Increased GABA(B) receptor-mediated signaling reduces the susceptibility of fragile X knockout mice to audiogenic seizures. Mol. Pharmacol. 2009, 76:18-24.
    • (2009) Mol. Pharmacol. , vol.76 , pp. 18-24
    • Pacey, L.K.1
  • 71
    • 6944247816 scopus 로고    scopus 로고
    • The Drosophila fragile X gene negatively regulates neuronal elaboration and synaptic differentiation
    • Pan L., et al. The Drosophila fragile X gene negatively regulates neuronal elaboration and synaptic differentiation. Curr. Biol. 2004, 14:1863-1870.
    • (2004) Curr. Biol. , vol.14 , pp. 1863-1870
    • Pan, L.1
  • 72
    • 41149114485 scopus 로고    scopus 로고
    • Mechanistic relationships between Drosophila fragile X mental retardation protein and metabotropic glutamate receptor A signaling
    • Pan L., et al. Mechanistic relationships between Drosophila fragile X mental retardation protein and metabotropic glutamate receptor A signaling. Mol. Cell. Neurosci. 2008, 37:747-760.
    • (2008) Mol. Cell. Neurosci. , vol.37 , pp. 747-760
    • Pan, L.1
  • 73
    • 15544368216 scopus 로고    scopus 로고
    • Store-operated calcium channels
    • Parekh A.B., Putney J.W. Store-operated calcium channels. Physiol. Rev. 2005, 85:757-810.
    • (2005) Physiol. Rev. , vol.85 , pp. 757-810
    • Parekh, A.B.1    Putney, J.W.2
  • 74
    • 46149087988 scopus 로고    scopus 로고
    • Elongation factor 2 and fragile X mental retardation protein control the dynamic translation of Arc/Arg3.1 essential for mGluR-LTD
    • Park S., et al. Elongation factor 2 and fragile X mental retardation protein control the dynamic translation of Arc/Arg3.1 essential for mGluR-LTD. Neuron 2008, 59:70-83.
    • (2008) Neuron , vol.59 , pp. 70-83
    • Park, S.1
  • 75
    • 0034194228 scopus 로고    scopus 로고
    • (Over)correction of FMR1 deficiency with YAC transgenics: behavioral and physical features
    • Peier A.M., et al. (Over)correction of FMR1 deficiency with YAC transgenics: behavioral and physical features. Hum. Mol. Genet. 2000, 9:1145-1159.
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 1145-1159
    • Peier, A.M.1
  • 76
    • 34147196414 scopus 로고    scopus 로고
    • Novel stimulus-induced calcium efflux in Drosophila mushroom bodies
    • Peng Y., Guo A. Novel stimulus-induced calcium efflux in Drosophila mushroom bodies. Eur. J. Neurosci. 2007, 25:2034-2044.
    • (2007) Eur. J. Neurosci. , vol.25 , pp. 2034-2044
    • Peng, Y.1    Guo, A.2
  • 77
    • 48549102737 scopus 로고    scopus 로고
    • Neuronal loss of Drosophila NPC1a causes cholesterol aggregation and age-progressive neurodegeneration
    • Phillips S.E., et al. Neuronal loss of Drosophila NPC1a causes cholesterol aggregation and age-progressive neurodegeneration. J. Neurosci. 2008, 28:6569-6582.
    • (2008) J. Neurosci. , vol.28 , pp. 6569-6582
    • Phillips, S.E.1
  • 78
    • 0027219753 scopus 로고
    • Frequenin-a novel calcium-binding protein that modulates synaptic efficacy in the Drosophila nervous system
    • Pongs O., et al. Frequenin-a novel calcium-binding protein that modulates synaptic efficacy in the Drosophila nervous system. Neuron 1993, 11:15-28.
    • (1993) Neuron , vol.11 , pp. 15-28
    • Pongs, O.1
  • 79
    • 0027768695 scopus 로고
    • Dependence of calmodulin localization in the retina on the NINAC unconventional myosin
    • Porter J.A., et al. Dependence of calmodulin localization in the retina on the NINAC unconventional myosin. Science 1993, 262:1038-1042.
    • (1993) Science , vol.262 , pp. 1038-1042
    • Porter, J.A.1
  • 80
    • 34247115505 scopus 로고    scopus 로고
    • Aging is associated with elevated intracellular calcium levels and altered calcium homeostatic mechanisms in hippocampal neurons
    • Raza M., et al. Aging is associated with elevated intracellular calcium levels and altered calcium homeostatic mechanisms in hippocampal neurons. Neurosci. Lett. 2007, 418:77-81.
    • (2007) Neurosci. Lett. , vol.418 , pp. 77-81
    • Raza, M.1
  • 81
    • 0027409006 scopus 로고
    • An invertebrate calcium-binding protein of the calbindin subfamily: protein structure, genomic organization, and expression pattern of the calbindin-32 gene of Drosophila
    • Reifegerste R., et al. An invertebrate calcium-binding protein of the calbindin subfamily: protein structure, genomic organization, and expression pattern of the calbindin-32 gene of Drosophila. J. Neurosci. 1993, 13:2186-2198.
    • (1993) J. Neurosci. , vol.13 , pp. 2186-2198
    • Reifegerste, R.1
  • 82
    • 18644370150 scopus 로고    scopus 로고
    • In vivo performance of genetically encoded indicators of neural activity in flies
    • Reiff D.F., et al. In vivo performance of genetically encoded indicators of neural activity in flies. J. Neurosci. 2005, 25:4766-4778.
    • (2005) J. Neurosci. , vol.25 , pp. 4766-4778
    • Reiff, D.F.1
  • 83
    • 61349164873 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor-mediated use-dependent down-regulation of synaptic excitability involves the fragile X mental retardation protein
    • Repicky S., Broadie K. Metabotropic glutamate receptor-mediated use-dependent down-regulation of synaptic excitability involves the fragile X mental retardation protein. J. Neurophysiol. 2009, 101:672-687.
    • (2009) J. Neurophysiol. , vol.101 , pp. 672-687
    • Repicky, S.1    Broadie, K.2
  • 84
    • 0028117351 scopus 로고
    • Implication of frequenin in the facilitation of transmitter release in Drosophila
    • Rivosecchi R., et al. Implication of frequenin in the facilitation of transmitter release in Drosophila. J. Physiol. 1994, 474:223-232.
    • (1994) J. Physiol. , vol.474 , pp. 223-232
    • Rivosecchi, R.1
  • 85
    • 0035675794 scopus 로고    scopus 로고
    • The behavioral phenotype in fragile X: symptoms of autism in very young children with fragile X syndrome, idiopathic autism, and other developmental disorders
    • Rogers S.J., et al. The behavioral phenotype in fragile X: symptoms of autism in very young children with fragile X syndrome, idiopathic autism, and other developmental disorders. J. Dev. Behav. Pediatr. 2001, 22:409-417.
    • (2001) J. Dev. Behav. Pediatr. , vol.22 , pp. 409-417
    • Rogers, S.J.1
  • 86
    • 35748986120 scopus 로고    scopus 로고
    • Chronic and acute alterations in the functional levels of frequenins 1 and 2 reveal their roles in synaptic transmission and axon terminal morphology
    • Romero-Pozuelo J., et al. Chronic and acute alterations in the functional levels of frequenins 1 and 2 reveal their roles in synaptic transmission and axon terminal morphology. Eur. J. Neurosci. 2007, 26:2428-2443.
    • (2007) Eur. J. Neurosci. , vol.26 , pp. 2428-2443
    • Romero-Pozuelo, J.1
  • 87
    • 34247340936 scopus 로고    scopus 로고
    • Expanding the neuron's calcium signaling repertoire: intracellular calcium release via voltage-induced PLC and IP3R activation
    • Ryglewski S., et al. Expanding the neuron's calcium signaling repertoire: intracellular calcium release via voltage-induced PLC and IP3R activation. PLoS Biol. 2007, 5:e66.
    • (2007) PLoS Biol. , vol.5
    • Ryglewski, S.1
  • 88
    • 0035099308 scopus 로고    scopus 로고
    • Epilepsy and EEG findings in 18 males with fragile X syndrome
    • Sabaratnam M., et al. Epilepsy and EEG findings in 18 males with fragile X syndrome. Seizure 2001, 10:60-63.
    • (2001) Seizure , vol.10 , pp. 60-63
    • Sabaratnam, M.1
  • 89
    • 0027966107 scopus 로고
    • Ion channel regulation by calmodulin binding
    • Saimi Y., Kung C. Ion channel regulation by calmodulin binding. FEBS Lett. 1994, 350:155-158.
    • (1994) FEBS Lett. , vol.350 , pp. 155-158
    • Saimi, Y.1    Kung, C.2
  • 90
    • 77649278678 scopus 로고    scopus 로고
    • Two frequenins in Drosophila: unveiling the evolutionary history of an unusual neuronal calcium sensor (NCS) duplication
    • Sanchez-Gracia A., et al. Two frequenins in Drosophila: unveiling the evolutionary history of an unusual neuronal calcium sensor (NCS) duplication. BMC Evol. Biol. 2010, 10:54.
    • (2010) BMC Evol. Biol. , vol.10 , pp. 54
    • Sanchez-Gracia, A.1
  • 91
    • 15544364246 scopus 로고    scopus 로고
    • Analysis of conditional paralytic mutants in Drosophila sarco-endoplasmic reticulum calcium ATPase reveals novel mechanisms for regulating membrane excitability
    • Sanyal S., et al. Analysis of conditional paralytic mutants in Drosophila sarco-endoplasmic reticulum calcium ATPase reveals novel mechanisms for regulating membrane excitability. Genetics 2005, 169:737-750.
    • (2005) Genetics , vol.169 , pp. 737-750
    • Sanyal, S.1
  • 92
    • 0035239006 scopus 로고    scopus 로고
    • Rapid plasticity of dendritic spine: hints to possible functions?
    • Segal M. Rapid plasticity of dendritic spine: hints to possible functions?. Prog. Neurobiol. 2001, 63:61-70.
    • (2001) Prog. Neurobiol. , vol.63 , pp. 61-70
    • Segal, M.1
  • 93
    • 80355125874 scopus 로고    scopus 로고
    • Primary neuronal cultures from the brains of late stage Drosophila pupae
    • Sicaeros B., et al. Primary neuronal cultures from the brains of late stage Drosophila pupae. J. Vis. Exp. 2007, 200.
    • (2007) J. Vis. Exp. , vol.200
    • Sicaeros, B.1
  • 94
    • 7244224871 scopus 로고    scopus 로고
    • Fragile X mental retardation protein is associated with translating polyribosomes in neuronal cells
    • Stefani G., et al. Fragile X mental retardation protein is associated with translating polyribosomes in neuronal cells. J. Neurosci. 2004, 24:7272-7276.
    • (2004) J. Neurosci. , vol.24 , pp. 7272-7276
    • Stefani, G.1
  • 95
    • 0141919602 scopus 로고    scopus 로고
    • Fast synaptic currents in Drosophila mushroom body Kenyon cells are mediated by alpha-bungarotoxin-sensitive nicotinic acetylcholine receptors and picrotoxin-sensitive GABA receptors
    • Su H., O'Dowd D.K. Fast synaptic currents in Drosophila mushroom body Kenyon cells are mediated by alpha-bungarotoxin-sensitive nicotinic acetylcholine receptors and picrotoxin-sensitive GABA receptors. J. Neurosci. 2003, 23:9246-9253.
    • (2003) J. Neurosci. , vol.23 , pp. 9246-9253
    • Su, H.1    O'Dowd, D.K.2
  • 96
    • 12344279989 scopus 로고    scopus 로고
    • Rgs4 mRNA expression is decreased in the brain of Fmr1 knockout mouse
    • Tervonen T., et al. Rgs4 mRNA expression is decreased in the brain of Fmr1 knockout mouse. Brain Res. Mol. Brain Res. 2005, 133:162-165.
    • (2005) Brain Res. Mol. Brain Res. , vol.133 , pp. 162-165
    • Tervonen, T.1
  • 97
    • 44449130390 scopus 로고    scopus 로고
    • Drosophila fragile X mental retardation protein developmentally regulates activity-dependent axon pruning
    • Tessier C.R., Broadie K. Drosophila fragile X mental retardation protein developmentally regulates activity-dependent axon pruning. Development 2008, 135:1547-1557.
    • (2008) Development , vol.135 , pp. 1547-1557
    • Tessier, C.R.1    Broadie, K.2
  • 98
    • 74749086909 scopus 로고    scopus 로고
    • Activity-dependent modulation of neural circuit synaptic connectivity
    • Tessier C.R., Broadie K. Activity-dependent modulation of neural circuit synaptic connectivity. Front Mol. Neurosci. 2009, 2:8.
    • (2009) Front Mol. Neurosci. , vol.2 , pp. 8
    • Tessier, C.R.1    Broadie, K.2
  • 99
    • 0345492360 scopus 로고    scopus 로고
    • The fragile X mental retardation protein is required for type-I metabotropic glutamate receptor-dependent translation of PSD-95
    • Todd P.K., et al. The fragile X mental retardation protein is required for type-I metabotropic glutamate receptor-dependent translation of PSD-95. Proc. Natl Acad. Sci. USA 2003, 100:14374-14378.
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 14374-14378
    • Todd, P.K.1
  • 100
    • 41849117708 scopus 로고    scopus 로고
    • A double-blind, parallel, multicenter comparison of l-acetylcarnitine with placebo on the attention deficit hyperactivity disorder in fragile X syndrome boys
    • Torrioli M.G., et al. A double-blind, parallel, multicenter comparison of l-acetylcarnitine with placebo on the attention deficit hyperactivity disorder in fragile X syndrome boys. Am. J. Med. Genet. A 2008, 146:803-812.
    • (2008) Am. J. Med. Genet. A , vol.146 , pp. 803-812
    • Torrioli, M.G.1
  • 101
    • 0033956907 scopus 로고    scopus 로고
    • Fragile X (fmr1) mRNA expression is differentially regulated in two adult models of activity-dependent gene expression
    • Valentine G., et al. Fragile X (fmr1) mRNA expression is differentially regulated in two adult models of activity-dependent gene expression. Brain Res. Mol. Brain Res. 2000, 75:337-341.
    • (2000) Brain Res. Mol. Brain Res. , vol.75 , pp. 337-341
    • Valentine, G.1
  • 102
    • 0036878801 scopus 로고    scopus 로고
    • The endoplasmic reticulum and neuronal calcium signalling
    • Verkhratsky A. The endoplasmic reticulum and neuronal calcium signalling. Cell Calcium 2002, 32:393-404.
    • (2002) Cell Calcium , vol.32 , pp. 393-404
    • Verkhratsky, A.1
  • 103
    • 62149115738 scopus 로고    scopus 로고
    • Rolling blackout is required for bulk endocytosis in non-neuronal cells and neuronal synapses
    • Vijayakrishnan N., et al. Rolling blackout is required for bulk endocytosis in non-neuronal cells and neuronal synapses. J. Cell Sci. 2009, 122:114-125.
    • (2009) J. Cell Sci. , vol.122 , pp. 114-125
    • Vijayakrishnan, N.1
  • 104
    • 35548930804 scopus 로고    scopus 로고
    • Multiple Gq-coupled receptors converge on a common protein synthesis-dependent long-term depression that is affected in fragile X syndrome mental retardation
    • Volk L.J., et al. Multiple Gq-coupled receptors converge on a common protein synthesis-dependent long-term depression that is affected in fragile X syndrome mental retardation. J. Neurosci. 2007, 27:11624-11634.
    • (2007) J. Neurosci. , vol.27 , pp. 11624-11634
    • Volk, L.J.1
  • 105
    • 0346656871 scopus 로고    scopus 로고
    • Developmentally-programmed FMRP expression in oligodendrocytes: a potential role of FMRP in regulating translation in oligodendroglia progenitors
    • Wang H., et al. Developmentally-programmed FMRP expression in oligodendrocytes: a potential role of FMRP in regulating translation in oligodendroglia progenitors. Hum. Mol. Genet. 2004, 13:79-89.
    • (2004) Hum. Mol. Genet. , vol.13 , pp. 79-89
    • Wang, H.1
  • 106
    • 3242753324 scopus 로고    scopus 로고
    • Stereotyped odor-evoked activity in the mushroom body of Drosophila revealed by green fluorescent protein-based Ca2+ imaging
    • Wang Y., et al. Stereotyped odor-evoked activity in the mushroom body of Drosophila revealed by green fluorescent protein-based Ca2+ imaging. J. Neurosci. 2004, 24:6507-6514.
    • (2004) J. Neurosci. , vol.24 , pp. 6507-6514
    • Wang, Y.1
  • 107
    • 49849098290 scopus 로고    scopus 로고
    • FMRP acts as a key messenger for dopamine modulation in the forebrain
    • Wang H., et al. FMRP acts as a key messenger for dopamine modulation in the forebrain. Neuron 2008, 59:634-647.
    • (2008) Neuron , vol.59 , pp. 634-647
    • Wang, H.1
  • 108
    • 43749093221 scopus 로고    scopus 로고
    • Roles of calcium-stimulated adenylyl cyclase and calmodulin-dependent protein kinase IV in the regulation of FMRP by group I metabotropic glutamate receptors
    • Wang H., et al. Roles of calcium-stimulated adenylyl cyclase and calmodulin-dependent protein kinase IV in the regulation of FMRP by group I metabotropic glutamate receptors. J. Neurosci. 2008, 28:4385-4397.
    • (2008) J. Neurosci. , vol.28 , pp. 4385-4397
    • Wang, H.1
  • 109
    • 2942715357 scopus 로고    scopus 로고
    • The fragile X-related gene affects the crawling behavior of Drosophila larvae by regulating the mRNA level of the DEG/ENaC protein pickpocket1
    • Xu K., et al. The fragile X-related gene affects the crawling behavior of Drosophila larvae by regulating the mRNA level of the DEG/ENaC protein pickpocket1. Curr. Biol. 2004, 14:1025-1034.
    • (2004) Curr. Biol. , vol.14 , pp. 1025-1034
    • Xu, K.1
  • 110
    • 0037218895 scopus 로고    scopus 로고
    • Detection of calcium transients in Drosophila mushroom body neurons with camgaroo reporters
    • Yu D., et al. Detection of calcium transients in Drosophila mushroom body neurons with camgaroo reporters. J. Neurosci. 2003, 23:64-72.
    • (2003) J. Neurosci. , vol.23 , pp. 64-72
    • Yu, D.1
  • 111
    • 33947257624 scopus 로고    scopus 로고
    • Drosophila alpha/beta mushroom body neurons form a branch-specific, long-term cellular memory trace after spaced olfactory conditioning
    • Yu D., et al. Drosophila alpha/beta mushroom body neurons form a branch-specific, long-term cellular memory trace after spaced olfactory conditioning. Neuron 2006, 52:845-855.
    • (2006) Neuron , vol.52 , pp. 845-855
    • Yu, D.1
  • 112
    • 33748457881 scopus 로고    scopus 로고
    • Fmrp is required for the establishment of the startle response during the critical period of auditory development
    • Yun S.W., et al. Fmrp is required for the establishment of the startle response during the critical period of auditory development. Brain Res. 2006, 1110:159-165.
    • (2006) Brain Res. , vol.1110 , pp. 159-165
    • Yun, S.W.1
  • 113
    • 0037423293 scopus 로고    scopus 로고
    • The fragile X syndrome protein FMRP associates with BC1 RNA and regulates the translation of specific mRNAs at synapses
    • Zalfa F., et al. The fragile X syndrome protein FMRP associates with BC1 RNA and regulates the translation of specific mRNAs at synapses. Cell 2003, 112:317-327.
    • (2003) Cell , vol.112 , pp. 317-327
    • Zalfa, F.1
  • 114
    • 34247485947 scopus 로고    scopus 로고
    • A new function for the fragile X mental retardation protein in regulation of PSD-95 mRNA stability
    • Zalfa F., et al. A new function for the fragile X mental retardation protein in regulation of PSD-95 mRNA stability. Nat. Neurosci. 2007, 10:578-587.
    • (2007) Nat. Neurosci. , vol.10 , pp. 578-587
    • Zalfa, F.1
  • 115
    • 71849091938 scopus 로고    scopus 로고
    • Neuromodulation at single presynaptic boutons of cerebellar parallel fibers is determined by bouton size and basal action potential-evoked Ca transient amplitude
    • Zhang W., Linden D.J. Neuromodulation at single presynaptic boutons of cerebellar parallel fibers is determined by bouton size and basal action potential-evoked Ca transient amplitude. J. Neurosci. 2009, 29:15586-15594.
    • (2009) J. Neurosci. , vol.29 , pp. 15586-15594
    • Zhang, W.1    Linden, D.J.2
  • 116
    • 0035977134 scopus 로고    scopus 로고
    • Drosophila fragile X-related gene regulates the MAP1B homolog Futsch to control synaptic structure and function
    • Zhang Y.Q., et al. Drosophila fragile X-related gene regulates the MAP1B homolog Futsch to control synaptic structure and function. Cell 2001, 107:591-603.
    • (2001) Cell , vol.107 , pp. 591-603
    • Zhang, Y.Q.1
  • 117
    • 23744492534 scopus 로고    scopus 로고
    • Deficits in trace fear memory and long-term potentiation in a mouse model for fragile X syndrome
    • Zhao M.G., et al. Deficits in trace fear memory and long-term potentiation in a mouse model for fragile X syndrome. J. Neurosci. 2005, 25:7385-7392.
    • (2005) J. Neurosci. , vol.25 , pp. 7385-7392
    • Zhao, M.G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.