Visual experience regulates transient expression and dendritic localization of fragile X mental retardation protein

Journal of Neuroscience

Volumn 24, Issue 47, 2004, Pages 10579-10583

  Gabel, Lisa A ^a   Won, Sandra ^a   Kawai, Hideki ^a   McKinney, Margaret ^a   Tartakoff, Alan M ^b   Fallon, Justin R ^a  

^a BROWN UNIVERSITY   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Dark reared; FMRP; Fragile X mental retardation; mGluR; NMDA; Synaptoneurosomes

Indexed keywords

FRAGILE X MENTAL RETARDATION PROTEIN; MESSENGER RNA; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PROTEIN KINASE (CALCIUM,CALMODULIN) II; RNA BINDING PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DENDRITIC CELL; FRAGILE X SYNDROME; GENETIC TRANSCRIPTION; LIGHT EXPOSURE; MENTAL DEFICIENCY; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS; RAT; RECEPTOR BLOCKING; VISION; VISUAL CORTEX;

ANIMALS; DARKNESS; DENDRITES; FRAGILE X MENTAL RETARDATION PROTEIN; IMMUNOHISTOCHEMISTRY; LIGHT; NERVE TISSUE PROTEINS; NEURONAL PLASTICITY; NEURONS; PHOTIC STIMULATION; RATS; RATS, LONG-EVANS; RECEPTORS, N-METHYL-D-ASPARTATE; RNA, MESSENGER; RNA-BINDING PROTEINS; SYNAPSES; TIME FACTORS; UP-REGULATION; VISUAL CORTEX;

EID: 9344246891     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2185-04.2004     Document Type: Article

References (25)

1. Adinolfi S, Bagni C, Musco G, Gibson T, Mazzarella L, Pastore A (1999) Dissecting FMR1, the protein responsible for fragile X syndrome, in its structural and functional domains. RNA 5:1248-1258.
2. Antar LN, Afroz R, Dictenberg JB, Carroll RC, Bassell GJ (2004) Metabotropic glutamate receptor activation regulates fragile X mental retardation protein and Fmr1 mRNA localization differentially in dendrites and at synapses. J Neurosci 24:2648-2655.
3. Bardoni B, Willemsen R, Weiler IJ, Schenck A, Severijnen LA, Hindelang C, Lalli E, Mandel JL (2003) NUFIP1 (nuclear FMRP interacting protein 1) is a nucleocytoplasmic shuttling protein associated with active synaptoneurosomes. Exp Cell Res 289:95-107.
4. Bear MF, Kleinschmidt A, Gu QA, Singer W (1990) Disruption of experience-dependent synaptic modifications in striate cortex by infusion of an NMDA receptor antagonist. J Neurosci 10:909-925.
5. Caudy AA, Myers M, Hannon GJ, Hammond SM (2002) Fragile X-related protein and VIG associate with the RNA interference machinery. Genes Dev 16:2491-2496.
6. Ceman S, O'Donnell WT, Reed M, Patton S, Pohl J, Warren ST (2003) Phosphorylation influences the translation state of FMRP-associated polyribosomes. Hum Mol Genet 12:3295-3305.
7. Ehlers MD (2003) Eppendorf 2003 prize-winning essay. Ubiquitin and the deconstruction of synapses. Science 302:800-801.
8. Fagiolini M, Pizzorusso T, Berardi N, Domenici L, Maffei L (1994) Functional postnatal development of the rat primary visual cortex and the role of visual experience: dark rearing and monocular deprivation. Vision Res 34:709-720.
9. Feng Y, Absher D, Eberhart DE, Brown V, Malter HE, Warren ST (1997) FMRP associates with polyribosomes as an mRNP, and the I304N mutation of severe fragile X syndrome abolishes this association. Mol Cell 1:109-118.
10. Galvez R, Gopal AR, Greenough WT (2003) Somatosensory cortical barrel dendritic abnormalities in a mouse model of the fragile X mental retardation syndrome. Brain Res 971:83-89.
11. Huber KM, Gallagher SM, Warren ST, Bear MF (2002) Altered synaptic plasticity in a mouse model of fragile X mental retardation. Proc Natl Acad Sci USA 99:7746-7750.
12. Jin P, Warren ST (2003) New insights into fragile X syndrome: from molecules to neurobehaviors. Trends Biochem Sci 28:152-158.
13. Jin P, Zarnescu DC, Ceman S, Nakamoto M, Mowrey J, Jongens TA, Nelson DL, Moses K, Warren ST (2004) Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway. Nat Neurosci 7:113-117.
14. Lee A, Li W, Xu K, Bogert BA, Su K, Gao FB (2003) Control of dendritic development by the Drosophila fragile X-related gene involves the small GTPase Rac1. Development 130:5543-5552.
15. Li J, Pelletier MR, Perez Velazquez JL, Carlen PL (2002) Reduced cortical synaptic plasticity and GluR1 expression associated with fragile X mental retardation protein deficiency. Mol Cell Neurosci 19:138-151.
16. Mazroui R, Huot ME, Tremblay S, Filion C, Labelle Y, Khandjian EW (2002) Trapping of messenger RNA by fragile X mental retardation protein into cytoplasmic granules induces translation repression. Hum Mol Genet 11:3007-3017.
17. Nimchinsky EA, Oberlander AM, Svoboda K (2001) Abnormal development of dendritic spines in FMR1 knock-out mice. J Neurosci 21:5139-5146.
18. Quinlan EM, Philpot BD, Huganir RL, Bear MF (1999) Rapid, experience-dependent expression of synaptic NMDA receptors in visual cortex in vivo. Nat Neurosci 2:352-357.
19. Sawtell NB, Huber KM, Roder JC, Bear MF (1999) Induction of NMDA receptor-dependent long-term depression in visual cortex does not require metabotropic glutamate receptors. J Neurophysiol 82:3594-3597.
20. Steward O, Worley P (2002) Local synthesis of proteins at synaptic sites on dendrites: role in synaptic plasticity and memory consolidation? Neurobiol Learn Mem 78:508-527.
21. Todd PK, Malter JS, Mack KJ (2003) Whisker stimulation-dependent translation of FMRP in the barrel cortex requires activation of type I metabotropic glutamate receptors. Brain Res Mol Brain Res 110:267-278.
22. Weiler IJ, Irwin SA, Klintsova AY, Spencer CM, Brazelton AD, Miyashiro K, Comery TA, Patel B, Eberwine J, Greenough WT (1997) Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activation. Proc Natl Acad Sci USA 94:5395-5400.
23. Wells D, Dong X, Quinlan E, Huang Y-S, Bear M, Richter J, Fallon J (2001) A role for the cytoplasmic polyadenylation element in NMDA receptor-regulated translation in neurons. J Neurosci 21:9541-9548.
24. Willemsen R, Oostra BA, Bassell GJ, Dictenberg J (2004) The fragile X syndrome: from molecular genetics to neurobiology. Ment Retard Dev Disabil Res Rev 10:60-67.
25. Wu L, Wells D, Tay J, Mendis D, Abbott MA, Barnitt A, Quinlan E, Heynen A, Fallon JR, Richter JD (1998) CPEB-mediated cytoplasmic polyadenylation and the regulation of experience-dependent translation of alpha-CaMKII mRNA at synapses. Neuron 21:1129-1139.