Human immunodeficiency virus protease inhibitors reduce the growth of human tumors via a proteasome-independent block of angiogenesis and matrix metalloproteinases

International Journal of Cancer

Volumn 128, Issue 1, 2011, Pages 82-93

  Toschi, Elena ^a   Sgadari, Cecilia ^a   Malavasi, Laura ^a,c   Bacigalupo, Ilaria ^a   Chiozzini, Chiara ^a   Carlei, Davide ^a   Compagnoni, Daniela ^a   Bellino, Stefania ^a   Bugarini, Roberto ^a   Falchi, Mario ^a   Palladino, Clelia ^a   Leone, Patrizia ^a   Barillari, Giovanni ^b,d   Monini, Paolo ^a   Ensoli, Barbara ^a  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^b UNIVERSITY OF ROME TOR VERGATA   (Italy)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

^d Genomic Health Inc   (United States)

Author keywords

Angiogenesis; HIV protease inhibitors; Matrix metalloproteinases; Proteasome activity

Indexed keywords

HUMAN IMMUNODEFICIENCY VIRUS PROTEINASE INHIBITOR; INDINAVIR; MATRIX METALLOPROTEINASE; PROTEASOME; SAQUINAVIR;

ADENOCARCINOMA; ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BREAST TUMOR; CANCER INHIBITION; CANCER INVASION; CELL INVASION; COLON TUMOR; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG TARGETING; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; LUNG TUMOR; MOUSE; NONHUMAN; PRIORITY JOURNAL; STEADY STATE; TUMOR CELL; TUMOR GROWTH;

ANIMALS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HIV PROTEASE INHIBITORS; HUMANS; IMMUNOHISTOCHEMISTRY; INDINAVIR; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASES; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; PROTEASOME ENDOPEPTIDASE COMPLEX; SAQUINAVIR; TUMOR BURDEN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 78349292526     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.25550     Document Type: Article

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