Effects of ionophores on liver CYP1A and 3A in male broilers

Journal of Veterinary Pharmacology and Therapeutics

Volumn 33, Issue 6, 2010, Pages 551-557

  Zhang, L L ^a   Zhang, J R ^a   Yu, Z G ^a   Zhao, J ^a   Mo, F ^a   Jiang, S X ^a  

^a NANJING AGRICULTURAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CAFFEINE; CYTOCHROME P450; CYTOCHROME P450 1A; CYTOCHROME P450 1A4; CYTOCHROME P450 1A5; CYTOCHROME P450 3A; CYTOCHROME P450 3A37; DAPSONE; MADURAMICIN; MESSENGER RNA; MONENSIN; PHENAZONE; SALINOMYCIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL FOOD; ANIMAL TISSUE; ARTICLE; CHICK; CONTROLLED STUDY; DRUG EFFECT; DRUG METABOLISM; ENZYME ACTIVITY; GENE EXPRESSION; GENETIC REGULATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIVER; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CAFFEINE; CHICKENS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP3A; DAPSONE; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION; IONOPHORES; LACTONES; LIVER; MALE; MICROSOMES, LIVER; MONENSIN; PYRANS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, MESSENGER;

CITRUS MAXIMA;

EID: 78349282287     PISSN: 01407783     EISSN: 13652885     Source Type: Journal    
DOI: 10.1111/j.1365-2885.2010.01168.x     Document Type: Article

References (44)

1. Badran, I. & Lekusova, D. (2006) Control of coccidiosis and different coccidia of chicken in selected technologies. Agricultura Tropica et Subtropica, 39, 39-41.
2. Bradford, M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical Biochemistry, 72, 248-254.
3. Brenes, A., Beyer, R.S., Cervantes, H.M. & Jensen, L.S. (1990) Dietary and monensin effects on activity of hepatic microsoma mixed function oxidase system in chickens. Poultry Science, 69, 1285-1291.
4. Cortright, K.A. & Craigmill, A.L. (2006) Cytochrome P450-dependent metabolism of midazolam in hepatic microsomes from chickens, turkeys, pheasant and bobwhite quail. Journal of Veterinary Pharmacology and Therapeutics, 29, 469-476.
5. Coulet, M., Eeckhueet, C. & Galtier, P. (1996) Ontogenic development of drug-metabolizing enzymes in male chicken liver. Canadian Journal of Physiology and Pharmacology, 74, 32-37.
6. Dacasto, M., Ceppa, L., Cornaglia, E., Valenza, F., Carletti, M., Bosio, A., Bosia, S., Ugazio, G. & Nebbia, C. (1999) Effects of the ionophore antibiotic monensin on hepatic biotransformations and target organ morphology in rats. Pharmacological Research, 39, 5-10.
7. Dion, A.K., Damaris, A.M. & Mark, T.H. (2009) Polyether ionophores: broad-spectrum and promising biologically active molecules for the control of drug-resistant bacteria and parasites. Expert Opinion on Drug Discovery, 4, 109-146.
8. Ershov, E., Bellaiche, M., Hanji, V., Soback, S., Gips, M., Weisman, Y. & Shlosberg, A. (2001) The effect of hepatic microsomal cytochrome P450 monooxygenases on monensin-sulfadimidine interactions in broilers. Journal of Veterinary Pharmacology and Therapeutics, 24, 73-76.
9. Fan, H., He, F., Li, Q., Huang, Y., Wei, G. & Xiao, S. (2004) Study on influence of ginsenoside Re on cytochrome P450 isoforms by cocktail approach using probe drugs, caffeine, chlorzoxazone, omeprazole, and dapsone in rats. Asian Journal of Drug Metabolic and Pharmacokinetics, 4, 91-98.
10. Frye, R.F. (2004) Probing the world of cytochrome P450 enzymes. Molecular Interventions, 3, 157-162.
11. Gilday, D., Gannon, M., Yutzey, K., Bader, D. & Rifkind, A.B. (1996) Molecular cloning and expression of two novel avian cytochrome P450 1A enzymes induced by 2, 3, 7, 8-tetrachlorodibenzop-dioxin. Journal of Biological Chemistry, 271, 33054-33059.
12. Handschin, C. & Meyer, U.A. (2003) Induction of drug metabolism: the role of nuclear receptors. Pharmacological Reviews, 55, 649-673.
13. Handschin, C., Meyer, U.A. & Podvinec, M. (2000) CXR, a chicken xenobiotic-sensing orphan nuclear receptor, is related to both mammalian pregnane X receptor (PXR) and constitutive androstane receptor (CAR). Proceedings of the National Academy of Sciences of the United States of America, 20, 10769-10774.
14. Handschin, C., Podvinec, M., Stockli, J., Hoffmann, K. & Meyer, U.A. (2001) Conservation of signaling pathways of xenobiotic-sensing orphan nuclear receptors, chicken xenobiotic receptor, constitutive androstane receptor, and pregnane X receptor, from birds to humans. Molecular Endocrinology, 9, 1571-1585.
15. Hansen, A.J., May, B.K. & Elferink, L.A. (1990) Sequence of a chicken phenobarbital-inducible cytochrome P450 cDNA: regulation of two P450 mRNAs transcribed from different genes. DNA, 9, 301-313.
16. Joseph, C.K., Michael, J.M., Karyn, D.H., Dorothy, E.F. & Badar, S. (2006) Hepatic CYP isoforms and drug-metabolizing enzyme activities in broiler chicks. International Journal of Poultry Science, 5, 104-111.
17. Judith, M.J., Calen, N., Doreen, M., Nadia, G., Heidi, S.W., Peter, R.S. & Jacqueline, F.S. (2000) Effect of arsenite on the induction of CYP1A4 and CYP1A5 in cultured chick embryo hepatocytes. Toxicology and Applied Pharmacology, 168, 177-182.
18. Khalil, W.F., Saitoh, T., Shimoda, M. & Kokue, E. (2001) In vitro cytochrome P450-mediated hepatic activities for five substrates in specific pathogen free chickens. Journal of Veterinary Pharmacology and Therapeutics, 24, 343-348.
19. Kubota, A., Iwata, H., Goldstone, M.H., Kim, E., Stegeman, J.J. & Tanabe, S. (2006) Cytochrome P450 1A4 and 1A5 in Common Cormorant (Phalacrocorax carbo): evolutionary relationships and functional implications associated with dioxin and related compounds. Toxicological Sciences, 92, 394-408.
20. Laemmli, U.K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature, 227, 680-685.
21. Lieber, C.S. (1997) Cytochrome P4502E1: its physiological and pathological role. Pharmacological Reviews, 77, 517-544.
22. Luu-The, V., Paquet, N., Calvo, E. & Cumps, J. (2005) Improved real-time RT-PCR method for highthroughput measurements using second derivative calculation and double correction. BioTechniques, 38, 287-293.
23. Mahajan, S.S. & Rifkind, A.B. (1999) Transcriptional activation of avian CYP1A4 and CYP1A5 by 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin: differences in gene expression and regulation compared to mammalian CYP1A1 and CYP1A2. Toxicology and Applied Pharmacology, 155, 96-106.
24. National Research Council. (1994) Nutrient Requirements of Poultry, 9th rev. edn. Natl. Acad. Press, Washington, DC.
25. Nebbia, C., Ceppa, L., Dacasto, M., Carletti, M. & Nachtmann, C. (1999) Oxidative metabolism of monensin in rat liver microsomes and interactions with tiamulin and other chemotherapeutic agents: evidence for the involvement of cytochrome P450 3A subfamily. Drug Metabolism and Disposition, 27, 1039-1044.
26. Nebbia, C., Ceppa, L., Dacasto, M., Nachtmann, C. & Carletti, M. (2001) Oxidative monensin metabolism and cytochrome P450 3A content and functions in liver microsomes from horses, pigs, broiler chicks, cattle and rats. Journal of Veterinary Pharmacology and Therapeutics, 24, 399-403.
27. Nosaka, H., Nadai, M., Kato, M., Yasui, K., Yoshizumi, H., Miyoshi, M., Zhao, Y.L., Baba, K., Takagi, K. & Hasegawa, T. (2006) Effect of a newly developed ketolide antibiotic, telithromycin, on metabolism of theophylline and expression of cytochrome P450 in rats. Life Science, 79, 50-56.
28. Oehme, F.W. & Pickrell, J.A. (1999) An analysis of the chronic oral toxicity of polyether ionophore antibiotics in animals. Veterinary & Human Toxicology, 41, 251-257.
29. Omura, T. & Sato, R. (1964) The carbon monoxide-binding pigment of liver microsomes II. Solubilization, purification, and properties. Journal of Biological Chemistry, 239, 2379-2385.
30. Ourlin, J.C., Baader, M., Fraser, D., Halpert, J.R. & Meyer, U.A. (2000) Cloning and functional expression of a first inducible avian cytochrome P450 of the CYP3A subfamily (CYP3A37). Archives of Biochemistry and Biophysics, 373, 375-384.
31. Ourlin, J.C., Handschin, C., Kaufmann, M. & Meyer, U.A. (2002) A link between cholesterol levels and phenobarbital induction of cytochromes P450. Biochemical and Biophysical Research Communications, 291, 378-384.
32. Ratz, V., Laczay, P., Mora, Z., Csiko, G., Monostori, K., Vereczkey, L., Lehel, J. & Semjen, G. (1997) Recent studies on the effects of tiamulin and monensin on hepatic cytochrome P450 activities in chickens and turkeys. Journal of Veterinary Pharmacology and Therapeutics, 20, 415-418.
33. Roder, J.D., Sanqiah, S., Lish, J.L. & Qualls, C.W. Jr (1996) The influence of ionophores on the duration of xylazine-ketamine anesthesia and the hepatic cytochrome P-450 content of broiler chickens. Veterinary & Human Toxicology, 38, 353-355.
34. Sawant, S.G., Terse, P.S. & Dalvi, R.R. (1990) Toxicity of dietary monensin in quail. Avian Diseases, 34, 571-574.
35. Sergent, T., Dupont, I., Jassogne, C., Ribonnet, L., Van-der-Heiden, E., Scippo, M.L., Muller, M., McAlister, D., Pussemier, L., Larondelle, Y. & Schneider, Y.J. (2009) CYP1A1 induction and CYP3A4 inhibition by the fungicide imazalil in the human intestinal Caco-2 cells- comparison with other conazole pesticides. Toxicology Letters, 184, 159-168.
36. Shah, V.P., Midha, K.K., Dighe, S., McGilveray, I.J., Skelly, J.P. & Yacobi, A. (1992) Analysis methods validation: bioavailability, bioequivalence and pharmacokinetics studies. Pharmaceutical Science, 81, 309-312.
37. Sharma, A., Pilote, S., Belanger, P.M., Arsenault, M. & Hamelin, B.A. (2004) A convenient five-drug cocktail for the assessment of major drug metabolizing enzymes: a pilot study. British Journal of Clinical Pharmacology, 58, 288-297.
38. Sharma, N., Bhalla, A., Varma, S., Jain, S. & Singh, S. (2005) Toxicity of maduramicin. Emergency Medicine Journal, 22, 880-882.
39. Sureshkumar, V., Venkateswaran, K.V. & Jayasundar, S. (2004) Interaction between enrofloxacin and monensin in broiler chickens. Veterinary & Human Toxicology, 46, 242-245.
40. Szucs, G., Tamási, V., Laczay, P. & Monostory, K. (2004) Biochemical background of toxic interaction between tiamulin and monensin. Chemico-Biological Interactions, 147, 151-161.
41. Tang, H., Min, G., Ge, B., Li, Y., Liu, X. & Jiang, S. (2008) Evaluation of protective effects of Chi-Zhi-Huang decoction on Phase I drug metabolism of liver injured rats by cocktail probe drugs. Journal of Ethnopharmacology, 117, 420-426.
42. Vaczi, P., Neuschl, J., Saly, J. & Lenhardt, L. (2006) Comparative of the acute toxicity of sodium salinomycin in synvertas and sacox preparation in chickens. Bulletin of the Veterinary Institute in Pulawy, 50, 379-382.
43. Watanabe, M.X., Iwata, H., Okamoto, M., Kim, E., Yoneda, K., Hashimoto, T. & Tanabe, S. (2005) Induction of cytochrome P450 1A5 mRNA, protein and enzymatic activities by dioxin-like compounds, and congener-specific metabolism and sequestration in the liver of wild jungle crow (Corvus macrorhynchos) from Tokyo. Toxicological Science, 88, 384-399.
44. Yang, Y.C., Zhang, W.G., Tang, Z.M., Liu, C.X., Sun, R.Y. & Yu, Z.L. (1988) 3P87 Practical Pharmacokinetics Program. Information of the Chinese Pharmacological Society, 5, 67.