Simvastatin induces osteogenic differentiation of murine embryonic stem cells

Journal of Bone and Mineral Research

Volumn 25, Issue 11, 2010, Pages 2470-2478

  Pagkalos, Joseph ^a   Cha, Jae Min ^a   Kang, Yunyi ^a   Heliotis, Manolis ^b   Tsiridis, Eleftherios ^a   Mantalaris, Athanasios ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b NORTHWICK PARK HOSPITAL   (United Kingdom)

Author keywords

murine embryonic stem cells; osteoinduction; simvastatin

Indexed keywords

ALIZARIN RED S; OSTEOCALCIN; OSTERIX; SIMVASTATIN; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

ANIMAL CELL; ARTICLE; BONE DEVELOPMENT; BONE TISSUE; CELL DIFFERENTIATION; CELL LINEAGE; CONTROLLED STUDY; CYTOTOXICITY; EMBRYONIC STEM CELL; GENE EXPRESSION; IN VITRO STUDY; MOUSE; NONHUMAN; TISSUE ENGINEERING;

ALKALINE PHOSPHATASE; ANIMALS; ANTHRAQUINONES; BONE MORPHOGENETIC PROTEIN 2; CELL DIFFERENTIATION; EMBRYONIC STEM CELLS; HEP G2 CELLS; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; MICE; OSTEOGENESIS; POLYMERASE CHAIN REACTION; SIMVASTATIN;

EID: 78349263029     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1002/jbmr.163     Document Type: Article

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