Reduced levels of two modifiers of epigenetic gene silencing, Dnmt3a and Trim28, cause increased phenotypic noise

Genome Biology

Volumn 11, Issue 11, 2010, Pages

  Whitelaw, Nadia C ^a,b   Chong, Suyinn ^a   Morgan, Daniel K ^a,b   Nestor, Colm ^c,d   Bruxner, Timothy J ^a   Ashe, Alyson ^a   Lambley, Eleanore ^a   Meehan, Richard ^c,d   Whitelaw, Emma ^a  

^a QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

^d UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DNA METHYLTRANSFERASE 3A; G PROTEIN COUPLED RECEPTOR; REGULATOR PROTEIN; TRIPARTITE MOTIF PROTEIN 28; UNCLASSIFIED DRUG; DNA (CYTOSINE 5) METHYLTRANSFERASE; NUCLEAR PROTEIN; REPRESSOR PROTEIN; TRIM28 PROTEIN, MOUSE;

ABNORMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; EPIGENETICS; FEMALE; GENE; GENE EXPRESSION PROFILING; GENE SILENCING; HETEROZYGOSITY; LIPID METABOLISM; MALE; MAS1 GENE; METABOLIC SYNDROME X; MOUSE; NONHUMAN; PENETRANCE; PHENOTYPIC VARIATION; TRANSCRIPTION REGULATION; ALLELE; ANIMAL; C57BL MOUSE; DNA MICROARRAY; GENETIC EPIGENESIS; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; GENETICS; GENOTYPE; MOUSE MUTANT; PHENOTYPE; SINGLE NUCLEOTIDE POLYMORPHISM;

MUS;

ALLELES; ANIMALS; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; EPIGENESIS, GENETIC; EPIGENOMICS; FEMALE; GENE SILENCING; GENETIC VARIATION; GENOTYPE; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NUCLEAR PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; REPRESSOR PROTEINS; TRANSCRIPTION, GENETIC;

EID: 78349251748     PISSN: 14747596     EISSN: 1474760X     Source Type: Journal    
DOI: 10.1186/gb-2010-11-11-r111     Document Type: Article

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