Insights into the transcriptional control of adipocyte differentiation

Journal of Cellular Biochemistry

Volumn 76, Issue SUPPL. 32/33, 1999, Pages 59-67

  Morrison, Ron F ^a   Farmer, Stephen R ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Adipocytes; Energy metabolism; Transcription

Indexed keywords

LEUCINE ZIPPER PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; STAT PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN; TRANSCRIPTION FACTOR; CCAAT ENHANCER BINDING PROTEIN; CELL RECEPTOR; DNA BINDING PROTEIN; MILK PROTEIN; MYOCYTE SPECIFIC ENHANCER BINDING FACTOR 2; MYOCYTE-SPECIFIC ENHANCER-BINDING FACTOR 2; MYOGENIC FACTOR; NUCLEAR PROTEIN; STAT5 PROTEIN; TRANSACTIVATOR PROTEIN;

ADIPOCYTE; ANIMAL TISSUE; ARTICLE; BROWN ADIPOSE TISSUE; CELL DIFFERENTIATION; CONTROLLED STUDY; ENERGY METABOLISM; LIPID METABOLISM; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; TRANSCRIPTION REGULATION; WHITE ADIPOSE TISSUE; ANIMAL; CYTOLOGY; DNA RESPONSIVE ELEMENT; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; REVIEW;

ANIMALIA;

ADIPOCYTES; ANIMALS; CCAAT-ENHANCER-BINDING PROTEINS; CELL DIFFERENTIATION; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; MILK PROTEINS; MYOGENIC REGULATORY FACTORS; NUCLEAR PROTEINS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RESPONSE ELEMENTS; STAT5 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 0033251387     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1097-4644(1999)75:32+<59::aid-jcb8>3.3.co;2-t     Document Type: Article

References (21)

1. Amri EZ, Dani C, Doglio A, Etienne J, Grimaldi P, Ailhaud G. 1986. Adipose cell differentiation: evidence for a two-step process in the polyamine-dependent Ob1754 clonal line. Biochem J 238:115-122.
2. Brown MS, Goldstein JL. 1997. The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor. Cell 89:331-340.
3. Brun RP, Spiegelman BM. 1997. PPAR gamma and the molecular control of adipogenesis. J Endocrinol 155:217-218.
4. Brun RP, Tontonoz P, Forman BM, Ellis R, Chen J, Evans RM, Spiegelman BM. 1996. Differential activation of adipogenesis by multiple PPAR isoforms. Genes Dev 10:974-984.
5. Cao Z, Umek RM, McKnight SL. 1991. Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells. Genes Dev 5:1538-1552.
6. Charron MJ, Katz EB, Olson AL. 1999. GLUT4 gene regulation and manipulation. J Biol Chem 274:3253-3256.
7. Christy RJ, Kaestner KH, Geiman DE, Lane MD. 1991. CCAAT/enhancer binding protein gene promoter: binding of nuclear factors during differentiation of 3T3-L1 preadipocytes. Proc Natl Acad Sci USA 88:2593-2597.
8. Clarke SL, Robinson CE, Gimble JM. 1997. CAAT/enhancer binding proteins directly modulate transcription from the peroxisome proliferator-activated receptor gamma 2 promoter. Biochem Biophys Res Commun 240:99-103.
9. Cornelius P, MacDougald OA, Lane MD. 1994. Regulation of adipocyte development. Annu Rev Nutr 14:99-129.
10. Darlington GJ, Ross SE, MacDougald OA. 1998. The role of C/EBP genes in adipocyte differentiation. J Biol Chem 273:30057-30060.
11. Darnell JE Jr. 1997. STATs and gene regulation. Science 277:1630-1635.
12. El-Jack AK, Hamm JK, Pilch PF, Farmer SR. 1999. Reconstitution of insulin-sensitive glucose transport in fibroblasts requires expression of both PPARgamma and C/EBPalpha. J Biol Chem 274:7946-7951.
13. Ericsson J, Jackson SM, Kim JB, Spiegelman BM, Edwards PA. 1997. Identification of glycerol-3-phosphate acyltransferase as an adipocyte determination and differentiation factor 1- and sterol regulatory element-binding protein-responsive gene. J Biol Chem 272:7298-7305.
14. Fajas L, Schoonjans K, Gelman L, Kim JB, Najib J, Martin G, Fruchart JC, Briggs M, Spiegelman BM, Auwerx J. 1999. Regulation of peroxisome proliferator-activated receptor gamma expression by adipocyte differentiation and determination factor 1/Sterol regulatory element binding protein 1: implications for adipocyte differentiation and metabolism. Mol Biol Cell 19:5495-5503.
15. Flier JS. 1998. Clinical review 94:. What's in a name? In search of leptin's physiologic role. J Clin Endocrinol Metab 83:1407-1413.
16. Gregoire FM, Smas CM, Sul HS. 1998. Understanding adipocyte differentiation. Physiol Rev 78:783-809.
17. Hollenberg AN, Susulic VS, Madura JP, Zhang B, Moller DE, Tontonoz P, Sarraf P, Spiegelman BM, Lowell BB. 1997. Functional antagonism between CCAAT/Enhancer binding protein-alpha and peroxisome proliferator-activated receptor-gamma on the leptin promoter. J Biol Chem 272:5283-5290.
18. Jiang MS, Tang QQ, McLenithan J, Geiman D, Shillinglaw W, Henzel WJ, Lane MD. 1998. Derepression of the C/EBPalpha gene during adipogenesis: identification of AP-2alpha as a repressor. Proc Natl Acad Sci USA 95:3467-3471.
19. Kim JB, Spiegelman BM. 1996. ADD1/SREBP1 promotes adipocyte differentiation and gene expression linked to fatty acid metabolism. Genes Dev 10:1096-1107.
20. Kim JB, Wright HM, Wright M, Spiegelman BM. 1999. ADD1/SREBP1 activates PPARγ through the production of endogenous ligand. Proc Natl Acad Sci USA 95:4333-4337.
21. Lane MD, Lin FT, MacDougald OA, Vasseur-Cognet M. 1996. Control of adipocyte differentiation by CCAAT/enhancer binding protein alpha (C/EBP alpha). Int J Obes Relat Metab Disord 20(suppl 3):S91-S96