-
2
-
-
0037180757
-
Inflammation and cancer
-
Coussens LM, Werb Z., Inflammation and cancer. Nature 2002; 420: 860-7.
-
(2002)
Nature
, vol.420
, pp. 860-7
-
-
Coussens, L.M.1
Werb, Z.2
-
3
-
-
0038676258
-
Regulation of wound healing by growth factors and cytokines
-
Werner S, Grose R., Regulation of wound healing by growth factors and cytokines. Physiol Rev 2003; 83: 835-70.
-
(2003)
Physiol Rev
, vol.83
, pp. 835-70
-
-
Werner, S.1
Grose, R.2
-
4
-
-
10644279947
-
Vascular endothelial growth factor and angiogenesis
-
Hoeben A, Landuyt B, Highley MS, Wildiers H, Van Oosterom AT, De Bruijn EA., Vascular endothelial growth factor and angiogenesis. Pharmacol Rev 2004; 56: 549-80.
-
(2004)
Pharmacol Rev
, vol.56
, pp. 549-80
-
-
Hoeben, A.1
Landuyt, B.2
Highley, M.S.3
Wildiers, H.4
Van Oosterom, A.T.5
De Bruijn, E.A.6
-
5
-
-
11844251984
-
Innate immunity and angiogenesis
-
Frantz S, Vincent KA, Feron O, Kelly RA., Innate immunity and angiogenesis. Circ Res 2005; 96: 15-26.
-
(2005)
Circ Res
, vol.96
, pp. 15-26
-
-
Frantz, S.1
Vincent, K.A.2
Feron, O.3
Kelly, R.A.4
-
6
-
-
38349014249
-
Wound healing is impaired in MyD88-deficient mice: A role for MyD88 in the regulation of wound healing by adenosine A2A receptors
-
Macedo L, Pinhal-Enfield G, Alshits V, Elson G, Cronstein BN, Leibovich SJ., Wound healing is impaired in MyD88-deficient mice: a role for MyD88 in the regulation of wound healing by adenosine A2A receptors. Am J Pathol 2007; 171: 1774-88.
-
(2007)
Am J Pathol;
, vol.171
, pp. 1774-88
-
-
MacEdo, L.1
Pinhal-Enfield, G.2
Alshits, V.3
Elson, G.4
Cronstein, B.N.5
Leibovich, S.J.6
-
7
-
-
0028931102
-
CpG motifs in bacterial DNA trigger direct B-cell activation
-
Krieg AM, Yi A, Matson S, Waldschmidt TJ, Bishop GA, Teasdale R, Koretzky GA, Klinman DM., CpG motifs in bacterial DNA trigger direct B-cell activation. Nature 1995; 374: 546-8.
-
(1995)
Nature
, vol.374
, pp. 546-8
-
-
Krieg, A.M.1
Yi, A.2
Matson, S.3
Waldschmidt, T.J.4
Bishop, G.A.5
Teasdale, R.6
Koretzky, G.A.7
Klinman, D.M.8
-
8
-
-
0029984358
-
CpG motifs expressed by bacterial DNA rapidly induce lymphocytes to secrete IL-6, IL-12 and IFNg
-
Klinman DM, Yi A, Beaucage SL, Conover J, Krieg AM., CpG motifs expressed by bacterial DNA rapidly induce lymphocytes to secrete IL-6, IL-12 and IFNg. Proc Natl Acad Sci USA 1996; 93: 2879-83.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 2879-83
-
-
Klinman, D.M.1
Yi, A.2
Beaucage, S.L.3
Conover, J.4
Krieg, A.M.5
-
9
-
-
0032995849
-
Bacterial CpG-DNA activates immune cells to signal "infectious danger."
-
Wagner H., Bacterial CpG-DNA activates immune cells to signal "infectious danger." Adv Immunol 1999; 73: 329-68.
-
(1999)
Adv Immunol
, vol.73
, pp. 329-68
-
-
Wagner, H.1
-
10
-
-
0034619794
-
A Toll-like receptor recognizes bacterial DNA
-
Hemmi H, Takeuchi O, Kawai T, Sato S, Sanjo H, Matsumoto M, Hoshino K, Wagner H, Takeda K, Akira S., A Toll-like receptor recognizes bacterial DNA. Nature 2000; 408: 740-5.
-
(2000)
Nature
, vol.408
, pp. 740-5
-
-
Hemmi, H.1
Takeuchi, O.2
Kawai, T.3
Sato, S.4
Sanjo, H.5
Matsumoto, M.6
Hoshino, K.7
Wagner, H.8
Takeda, K.9
Akira, S.10
-
11
-
-
0035477969
-
Cutting edge: Role of toll-like receptor 9 in CpG DNA-induced activation of human cells
-
Takeshita F, Leifer CA, Gursel I, Ishii K, Takeshita S, Gursel M, Klinman DM., Cutting edge: role of toll-like receptor 9 in CpG DNA-induced activation of human cells. J Immunol 2001; 167: 3555-8.
-
(2001)
J Immunol;
, vol.167
, pp. 3555-8
-
-
Takeshita, F.1
Leifer, C.A.2
Gursel, I.3
Ishii, K.4
Takeshita, S.5
Gursel, M.6
Klinman, D.M.7
-
12
-
-
1842631153
-
Immunotherapeutic uses of CpG oligodeoxynucleotides
-
Klinman DM., Immunotherapeutic uses of CpG oligodeoxynucleotides. Nat Rev Immunol 2004; 4: 249-58.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 249-58
-
-
Klinman, D.M.1
-
13
-
-
0037726807
-
A phase i study of the safety and immunogenicity of recombinant hepatitis B surface antigen co-administered with an immunostimulatory phosphorothioate oligonucleotide adjuvant
-
Halperin SA, Van Nest G, Smith B, Abtahi S, Whiley H, Eiden JJ., A phase I study of the safety and immunogenicity of recombinant hepatitis B surface antigen co-administered with an immunostimulatory phosphorothioate oligonucleotide adjuvant. Vaccine 2003; 21: 2461-7.
-
(2003)
Vaccine
, vol.21
, pp. 2461-7
-
-
Halperin, S.A.1
Van Nest, G.2
Smith, B.3
Abtahi, S.4
Whiley, H.5
Eiden, J.J.6
-
14
-
-
33745848601
-
-
ICAAC abstract LB-25
-
Rynkiewicz D, Rathkopf M, Ransom J, Sim I, Giri L, Quinn J, Waytes T, Al-Adhami M, Johnson W, Nielsen C., Marked enhancement of antibody response to anthrax vaccine adsorbed with CpG 7909 in healthy volunteers. ICAAC abstract LB-25, 2005.
-
(2005)
Marked enhancement of antibody response to anthrax vaccine adsorbed with CpG 7909 in healthy volunteers
-
-
Rynkiewicz, D.1
Rathkopf, M.2
Ransom, J.3
Sim, I.4
Giri, L.5
Quinn, J.6
Waytes, T.7
Al-Adhami, M.8
Johnson, W.9
Nielsen, C.10
-
15
-
-
61749098024
-
Immunotherapeutic applications of CpG oligodeoxynucleotide TLR9 agonists
-
Vollmer J, Krieg AM., Immunotherapeutic applications of CpG oligodeoxynucleotide TLR9 agonists. Adv Drug Deliv Rev 2009; 61: 195-204.
-
(2009)
Adv Drug Deliv Rev
, vol.61
, pp. 195-204
-
-
Vollmer, J.1
Krieg, A.M.2
-
16
-
-
0037173057
-
DNA containing CpG motifs induces angiogenesis
-
Zheng M, Klinman DM, Gierynska M, Rouse BT., DNA containing CpG motifs induces angiogenesis. Proc Natl Acad Sci USA 2002; 99: 8944-9.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 8944-9
-
-
Zheng, M.1
Klinman, D.M.2
Gierynska, M.3
Rouse, B.T.4
-
17
-
-
0041343279
-
An angiogenic switch in macrophages involving synergy between Toll-like receptors 2, 4, 7, and 9 and adenosine A(2A) receptors
-
Pinhal-Enfield G, Ramanathan M, Hasko G, Vogel SN, Salzman AL, Boons GJ, Leibovich SJ., An angiogenic switch in macrophages involving synergy between Toll-like receptors 2, 4, 7, and 9 and adenosine A(2A) receptors. Am J Pathol 2003; 163: 711-21.
-
(2003)
Am J Pathol
, vol.163
, pp. 711-21
-
-
Pinhal-Enfield, G.1
Ramanathan, M.2
Hasko, G.3
Vogel, S.N.4
Salzman, A.L.5
Boons, G.J.6
Leibovich, S.J.7
-
18
-
-
66149124876
-
A suppressive oligodeoxynucleotide inhibits ocular inflammation
-
Fujimoto C, Klinman DM, Shi G, Yin H, Vistica BP, Lovaas JD, Wawrousek EF, Igarashi T, Chan CC, Gery I., A suppressive oligodeoxynucleotide inhibits ocular inflammation. Clin Exp Immunol 2009; 156: 528-34.
-
(2009)
Clin Exp Immunol
, vol.156
, pp. 528-34
-
-
Fujimoto, C.1
Klinman, D.M.2
Shi, G.3
Yin, H.4
Vistica, B.P.5
Lovaas, J.D.6
Wawrousek, E.F.7
Igarashi, T.8
Chan, C.C.9
Gery, I.10
-
19
-
-
54049105664
-
Effect of CpG oligonucleotides on vaccine-induced B cell memory
-
Tross D, Klinman DM., Effect of CpG oligonucleotides on vaccine-induced B cell memory. J Immunol 2008; 181: 5785-90.
-
(2008)
J Immunol
, vol.181
, pp. 5785-90
-
-
Tross, D.1
Klinman, D.M.2
-
20
-
-
47249095737
-
Suppressive oligodeoxynucleotides inhibit silica-induced pulmonary inflammation
-
Sato T, Shimosato T, Alvord WG, Klinman DM., Suppressive oligodeoxynucleotides inhibit silica-induced pulmonary inflammation. J Immunol 2008; 180: 7648-54.
-
(2008)
J Immunol
, vol.180
, pp. 7648-54
-
-
Sato, T.1
Shimosato, T.2
Alvord, W.G.3
Klinman, D.M.4
-
21
-
-
0033883014
-
Delayed wound healing in CXCR2 knockout mice
-
Devalaraja RM, Nanney LB, Du J, Qian Q, Yu Y, Devalaraja MN, Richmond A., Delayed wound healing in CXCR2 knockout mice. J Invest Dermatol 2000; 115: 234-44.
-
(2000)
J Invest Dermatol
, vol.115
, pp. 234-44
-
-
Devalaraja, R.M.1
Nanney, L.B.2
Du, J.3
Qian, Q.4
Yu, Y.5
Devalaraja, M.N.6
Richmond, A.7
-
22
-
-
40449127195
-
Chemokine receptor CX3CR1 mediates skin wound healing by promoting macrophage and fibroblast accumulation and function
-
Ishida Y, Gao JL, Murphy PM., Chemokine receptor CX3CR1 mediates skin wound healing by promoting macrophage and fibroblast accumulation and function. J Immunol 2008; 180: 569-79.
-
(2008)
J Immunol
, vol.180
, pp. 569-79
-
-
Ishida, Y.1
Gao, J.L.2
Murphy, P.M.3
-
23
-
-
33749833683
-
Heme oxygenase-1, a potential biomarker of chronic silicosis, attenuates silica-induced lung injury
-
Sato T, Takeno M, Honma K, Yamauchi H, Saito Y, Sasaki T, Morikubo H, Nagashima Y, Takagi S, Yamanaka K, Kaneko T, Ishigatsubo Y., Heme oxygenase-1, a potential biomarker of chronic silicosis, attenuates silica-induced lung injury. Am J Respir Crit Care Med 2006; 174: 906-14.
-
(2006)
Am J Respir Crit Care Med
, vol.174
, pp. 906-14
-
-
Sato, T.1
Takeno, M.2
Honma, K.3
Yamauchi, H.4
Saito, Y.5
Sasaki, T.6
Morikubo, H.7
Nagashima, Y.8
Takagi, S.9
Yamanaka, K.10
Kaneko, T.11
Ishigatsubo, Y.12
-
24
-
-
33846463426
-
Morphometric analysis of murine skin wound healing: Standardization of experimental procedures and impact of an advanced multitissue array technique
-
Gerharz M, Baranowsky A, Siebolts U, Eming S, Nischt R, Krieg T, Wickenhauser C., Morphometric analysis of murine skin wound healing: standardization of experimental procedures and impact of an advanced multitissue array technique. Wound Repair Regen 2007; 15: 105-12.
-
(2007)
Wound Repair Regen;
, vol.15
, pp. 105-12
-
-
Gerharz, M.1
Baranowsky, A.2
Siebolts, U.3
Eming, S.4
Nischt, R.5
Krieg, T.6
Wickenhauser, C.7
-
25
-
-
0022499236
-
Basement membrane complexes with biological activity
-
Kleinman HK, McGarvey ML, Hassell JR, Star VL, Cannon FB, Laurie GW, Martin GR., Basement membrane complexes with biological activity. Biochemistry 1986; 25: 312-8.
-
(1986)
Biochemistry
, vol.25
, pp. 312-8
-
-
Kleinman, H.K.1
McGarvey, M.L.2
Hassell, J.R.3
Star, V.L.4
Cannon, F.B.5
Laurie, G.W.6
Martin, G.R.7
-
26
-
-
0036321006
-
Human chorionic gonadotropin inhibits Kaposi's sarcoma associated angiogenesis, matrix metalloprotease activity, and tumor growth
-
Pfeffer U, Bisacchi D, Morini M, Benelli R, Minghelli S, Vacca A, Noonan DM, Albini A., Human chorionic gonadotropin inhibits Kaposi's sarcoma associated angiogenesis, matrix metalloprotease activity, and tumor growth. Endocrin 2002; 143: 3114-21.
-
(2002)
Endocrin
, vol.143
, pp. 3114-21
-
-
Pfeffer, U.1
Bisacchi, D.2
Morini, M.3
Benelli, R.4
Minghelli, S.5
Vacca, A.6
Noonan, D.M.7
Albini, A.8
-
27
-
-
0034073739
-
Matrigel increases the rate of split wound healing and promotes keratinocyte utake' in deep wounds in rats
-
Gorelik JV, Paramonov BA, Blinova MI, Diakonov IA, Kukhareva LV, Pinaev GP., Matrigel increases the rate of split wound healing and promotes keratinocyte utake' in deep wounds in rats. Cytotechnology 2000; 32: 79-86.
-
(2000)
Cytotechnology
, vol.32
, pp. 79-86
-
-
Gorelik, J.V.1
Paramonov, B.A.2
Blinova, M.I.3
Diakonov, I.A.4
Kukhareva, L.V.5
Pinaev, G.P.6
-
28
-
-
33748797690
-
CpG-mediated changes in gene expression in murine spleen cells identified by microarray analysis
-
Klaschik S, Gursel I, Klinman DM., CpG-mediated changes in gene expression in murine spleen cells identified by microarray analysis. Mol Immunol 2007; 44: 1095-104.
-
(2007)
Mol Immunol
, vol.44
, pp. 1095-104
-
-
Klaschik, S.1
Gursel, I.2
Klinman, D.M.3
-
29
-
-
40449127195
-
Chemokine receptor CX3CR1 mediates skin wound healing by promoting macrophage and fibroblast accumulation and function
-
Ishida Y, Gao JL, Murphy PM., Chemokine receptor CX3CR1 mediates skin wound healing by promoting macrophage and fibroblast accumulation and function. J Immunol 2008; 180: 569-79.
-
(2008)
J Immunol
, vol.180
, pp. 569-79
-
-
Ishida, Y.1
Gao, J.L.2
Murphy, P.M.3
-
30
-
-
33749148761
-
CpG DNA activates survival in murine macrophages through TLR9 and the phosphatidylinositol 3-kinase-Akt pathway
-
Sester DP, Brion K, Trieu A, Goodridge HS, Roberts TL, Dunn J, Hume DA, Stacey KJ, Sweet MJ., CpG DNA activates survival in murine macrophages through TLR9 and the phosphatidylinositol 3-kinase-Akt pathway. J Immunol 2006; 177: 4473-80.
-
(2006)
J Immunol
, vol.177
, pp. 4473-80
-
-
Sester, D.P.1
Brion, K.2
Trieu, A.3
Goodridge, H.S.4
Roberts, T.L.5
Dunn, J.6
Hume, D.A.7
Stacey, K.J.8
Sweet, M.J.9
-
31
-
-
2442717879
-
Topical vascular endothelial growth factor accelerates diabetic wound healing through increased angiogenesis and by mobilizing and recruiting bone marrow-derived cells
-
Galiano RD, Tepper OM, Pelo CR, Bhatt KA, Callaghan M, Bastidas N, Bunting S, Steinmetz HG, Gurtner GC., Topical vascular endothelial growth factor accelerates diabetic wound healing through increased angiogenesis and by mobilizing and recruiting bone marrow-derived cells. Am J Pathol 2004; 164: 1935-47.
-
(2004)
Am J Pathol
, vol.164
, pp. 1935-47
-
-
Galiano, R.D.1
Tepper, O.M.2
Pelo, C.R.3
Bhatt, K.A.4
Callaghan, M.5
Bastidas, N.6
Bunting, S.7
Steinmetz, H.G.8
Gurtner, G.C.9
-
32
-
-
33845430467
-
Pseudomonas lipopolysaccharide accelerates wound repair via activation of a novel epithelial cell signaling cascade
-
Koff JL, Shao MX, Kim S, Ueki IF, Nadel JA., Pseudomonas lipopolysaccharide accelerates wound repair via activation of a novel epithelial cell signaling cascade. J Immunol 2006; 177: 8693-700.
-
(2006)
J Immunol
, vol.177
, pp. 8693-700
-
-
Koff, J.L.1
Shao, M.X.2
Kim, S.3
Ueki, I.F.4
Nadel, J.A.5
-
33
-
-
66149124876
-
A suppressive oligodeoxynucleotide inhibits ocular inflammation
-
Fujimoto C, Klinman DM, Yin H, Vistica BP, Wawrousek EF, Igarashi T, Chan C, Gery I., A suppressive oligodeoxynucleotide inhibits ocular inflammation. Clin Immunol Immunolpathol 2009; l156: 528-34.
-
(2009)
Clin Immunol Immunolpathol
, vol.156
, pp. 528-34
-
-
Fujimoto, C.1
Klinman, D.M.2
Yin, H.3
Vistica, B.P.4
Wawrousek, E.F.5
Igarashi, T.6
Chan, C.7
Gery, I.8
-
34
-
-
33745946911
-
Therapeutic potential of Toll-like receptor 9 activation
-
Krieg AM., Therapeutic potential of Toll-like receptor 9 activation. Nat Rev Drug Discov 2006; 5: 471-84.
-
(2006)
Nat Rev Drug Discov
, vol.5
, pp. 471-84
-
-
Krieg, A.M.1
-
35
-
-
0037083664
-
CpG oligodeoxynucleotides as vaccine adjuvants in primates
-
Verthelyi D, Kenney RT, Seder RA, Gam AA, Friedag B, Klinman DM., CpG oligodeoxynucleotides as vaccine adjuvants in primates. J Immunol 2002; 168: 1659-63.
-
(2002)
J Immunol
, vol.168
, pp. 1659-63
-
-
Verthelyi, D.1
Kenney, R.T.2
Seder, R.A.3
Gam, A.A.4
Friedag, B.5
Klinman, D.M.6
-
36
-
-
50549084485
-
Randomized phase II trial of a toll-like receptor 9 agonist oligodeoxynucleotide, PF-3512676, in combination with first-line taxane plus platinum chemotherapy for advanced-stage non-small-cell lung cancer
-
Manegold C, Gravenor D, Woytowitz D, Mezger J, Hirsh V, Albert G, Al-Adhami M, Readett D, Krieg AM, Leichman CG., Randomized phase II trial of a toll-like receptor 9 agonist oligodeoxynucleotide, PF-3512676, in combination with first-line taxane plus platinum chemotherapy for advanced-stage non-small-cell lung cancer. J Clin Oncol 2008; 26: 3979-86.
-
(2008)
J Clin Oncol
, vol.26
, pp. 3979-86
-
-
Manegold, C.1
Gravenor, D.2
Woytowitz, D.3
Mezger, J.4
Hirsh, V.5
Albert, G.6
Al-Adhami, M.7
Readett, D.8
Krieg, A.M.9
Leichman, C.G.10
|