-
1
-
-
0031904566
-
Effects of oxygen on protein carbonyl and aging in Caenorhabditis elegans mutants with long (age-1) and short (mev-1) life spans
-
Adachi H, Fujiwara Y, Ishii N (1998) Effects of oxygen on protein carbonyl and aging in Caenorhabditis elegans mutants with long (age-1) and short (mev-1) life spans. J. Gerontol. A Biol. Sci. Med. Sci. 53, B240-B244.
-
(1998)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.53
-
-
Adachi, H.1
Fujiwara, Y.2
Ishii, N.3
-
2
-
-
0242585476
-
Asymmetric inheritance of oxidatively damaged proteins during cytokinesis
-
Aguilaniu H, Gustafsson L, Rigoulet M, Nystrom T (2003) Asymmetric inheritance of oxidatively damaged proteins during cytokinesis. Science 299, 1751-1753.
-
(2003)
Science
, vol.299
, pp. 1751-1753
-
-
Aguilaniu, H.1
Gustafsson, L.2
Rigoulet, M.3
Nystrom, T.4
-
3
-
-
72449170138
-
Starvation protects germline stem cells and extends reproductive longevity in C. elegans
-
Angelo G, Van Gilst MR (2009) Starvation protects germline stem cells and extends reproductive longevity in C. elegans. Science 326, 954-958.
-
(2009)
Science
, vol.326
, pp. 954-958
-
-
Angelo, G.1
Van Gilst, M.R.2
-
4
-
-
0016853664
-
A model for conformational coupling of membrane potential and proton translocation to ATP synthesis and to active transport
-
Boyer PD (1975) A model for conformational coupling of membrane potential and proton translocation to ATP synthesis and to active transport. FEBS Lett. 58, 1-6.
-
(1975)
FEBS Lett.
, vol.58
, pp. 1-6
-
-
Boyer, P.D.1
-
5
-
-
0016063911
-
The geFnetics of Caenorhabditis elegans
-
Brenner S (1974) The geFnetics of Caenorhabditis elegans. Genetics 77, 71-94.
-
(1974)
Genetics
, vol.77
, pp. 71-94
-
-
Brenner, S.1
-
6
-
-
0035839573
-
Oxidative modification and inactivation of the proteasome during coronary occlusion/reperfusion
-
Bulteau AL, Lundberg KC, Humphries KM, Sadek HA, Szweda PA, Friguet B, Szweda LI (2001) Oxidative modification and inactivation of the proteasome during coronary occlusion/reperfusion. J. Biol. Chem. 276, 30057-30063.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 30057-30063
-
-
Bulteau, A.L.1
Lundberg, K.C.2
Humphries, K.M.3
Sadek, H.A.4
Szweda, P.A.5
Friguet, B.6
Szweda, L.I.7
-
7
-
-
0036208170
-
Protein degradation during aging: the lysosome-, the calpain- and the proteasome-dependent cellular proteolytic systems
-
Chondrogianni N, Fragoulis EG, Gonos ES (2002) Protein degradation during aging: the lysosome-, the calpain- and the proteasome-dependent cellular proteolytic systems. Biogerontology 3, 121-123.
-
(2002)
Biogerontology
, vol.3
, pp. 121-123
-
-
Chondrogianni, N.1
Fragoulis, E.G.2
Gonos, E.S.3
-
8
-
-
0038475847
-
Protein carbonylation in human diseases
-
Dalle-Donne I, Giustarini D, Colombo R, Rossi R, Milzani A (2003) Protein carbonylation in human diseases. Trends Mol. Med. 9, 169-176.
-
(2003)
Trends Mol. Med.
, vol.9
, pp. 169-176
-
-
Dalle-Donne, I.1
Giustarini, D.2
Colombo, R.3
Rossi, R.4
Milzani, A.5
-
9
-
-
38449093531
-
Immunohistochemistry
-
Duerr JS (2006). Immunohistochemistry. WormBook, 1-61.
-
(2006)
WormBook
, pp. 1-61
-
-
Duerr, J.S.1
-
10
-
-
33750195046
-
Mitochondrial DNA clonality in the dock: can surveillance swing the case?
-
Elson JL, Lightowlers RN (2006) Mitochondrial DNA clonality in the dock: can surveillance swing the case? Trends Genet. 22, 603-607.
-
(2006)
Trends Genet.
, vol.22
, pp. 603-607
-
-
Elson, J.L.1
Lightowlers, R.N.2
-
11
-
-
34547410267
-
Sir2p-dependent protein segregation gives rise to a superior reactive oxygen species management in the progeny of Saccharomyces cerevisiae
-
Erjavec N, Nystrom T (2007) Sir2p-dependent protein segregation gives rise to a superior reactive oxygen species management in the progeny of Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. U S A 104, 10877-10881.
-
(2007)
Proc. Natl. Acad. Sci. U S A
, vol.104
, pp. 10877-10881
-
-
Erjavec, N.1
Nystrom, T.2
-
12
-
-
34948846000
-
Accelerated aging and failure to segregate damaged proteins in Sir2 mutants can be suppressed by overproducing the protein aggregation-remodeling factor Hsp104p
-
Erjavec N, Larsson L, Grantham J, Nystrom T (2007) Accelerated aging and failure to segregate damaged proteins in Sir2 mutants can be suppressed by overproducing the protein aggregation-remodeling factor Hsp104p. Genes Dev. 21, 2410-2421.
-
(2007)
Genes Dev.
, vol.21
, pp. 2410-2421
-
-
Erjavec, N.1
Larsson, L.2
Grantham, J.3
Nystrom, T.4
-
13
-
-
57749089780
-
Selective benefits of damage partitioning in unicellular systems and its effects on aging
-
Erjavec N, Cvijovic M, Klipp E, Nystrom T (2008) Selective benefits of damage partitioning in unicellular systems and its effects on aging. Proc. Natl. Acad. Sci. U S A 105, 18764-18769.
-
(2008)
Proc. Natl. Acad. Sci. U S A
, vol.105
, pp. 18764-18769
-
-
Erjavec, N.1
Cvijovic, M.2
Klipp, E.3
Nystrom, T.4
-
14
-
-
39349105943
-
A mouse model of mitochondrial disease reveals germline selection against severe mtDNA mutations
-
Fan W, Waymire KG, Narula N, Li P, Rocher C, Coskun PE, Vannan MA, Narula J, Macgregor GR, Wallace DC (2008) A mouse model of mitochondrial disease reveals germline selection against severe mtDNA mutations. Science 319, 958-962.
-
(2008)
Science
, vol.319
, pp. 958-962
-
-
Fan, W.1
Waymire, K.G.2
Narula, N.3
Li, P.4
Rocher, C.5
Coskun, P.E.6
Vannan, M.A.7
Narula, J.8
Macgregor, G.R.9
Wallace, D.C.10
-
15
-
-
33646578189
-
Oxidized protein degradation and repair in ageing and oxidative stress
-
Friguet B (2006) Oxidized protein degradation and repair in ageing and oxidative stress. FEBS Lett. 580, 2910-2916.
-
(2006)
FEBS Lett.
, vol.580
, pp. 2910-2916
-
-
Friguet, B.1
-
16
-
-
70350660932
-
Ageing and oxidants in the nematode Caenorhabditis elegans
-
Gems D (2009) Ageing and oxidants in the nematode Caenorhabditis elegans. SEB Exp. Biol. Ser. 62, 31-56.
-
(2009)
SEB Exp. Biol. Ser.
, vol.62
, pp. 31-56
-
-
Gems, D.1
-
17
-
-
66749126389
-
Antioxidant defense and aging in C. elegans: is the oxidative damage theory of aging wrong?
-
Gems D, Doonan R (2009) Antioxidant defense and aging in C. elegans: is the oxidative damage theory of aging wrong? Cell Cycle. 8, 1681-1687.
-
(2009)
Cell Cycle.
, vol.8
, pp. 1681-1687
-
-
Gems, D.1
Doonan, R.2
-
18
-
-
0032734242
-
Receptor-mediated endocytosis in the Caenorhabditis elegans oocyte
-
Grant B, Hirsh D (1999) Receptor-mediated endocytosis in the Caenorhabditis elegans oocyte. Mol. Biol. Cell 10, 4311-4326.
-
(1999)
Mol. Biol. Cell
, vol.10
, pp. 4311-4326
-
-
Grant, B.1
Hirsh, D.2
-
19
-
-
0030982143
-
Degradation of oxidized proteins in mammalian cells
-
Grune T, Reinheckel T, Davies KJ (1997) Degradation of oxidized proteins in mammalian cells. FASEB J. 11, 526-534.
-
(1997)
FASEB J.
, vol.11
, pp. 526-534
-
-
Grune, T.1
Reinheckel, T.2
Davies, K.J.3
-
20
-
-
0038239701
-
Selective degradation of oxidatively modified protein substrates by the proteasome
-
Grune T, Merker K, Sandig G, Davies KJ (2003) Selective degradation of oxidatively modified protein substrates by the proteasome. Biochem. Biophys. Res. Commun. 305, 709-718.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.305
, pp. 709-718
-
-
Grune, T.1
Merker, K.2
Sandig, G.3
Davies, K.J.4
-
21
-
-
4344677922
-
Decreased proteolysis caused by protein aggregates, inclusion bodies, plaques, lipofuscin, ceroid, and 'aggresomes' during oxidative stress, aging, and disease
-
Grune T, Jung T, Merker K, Davies KJ (2004) Decreased proteolysis caused by protein aggregates, inclusion bodies, plaques, lipofuscin, ceroid, and 'aggresomes' during oxidative stress, aging, and disease. Int. J. Biochem. Cell Biol. 36, 2519-2530.
-
(2004)
Int. J. Biochem. Cell Biol.
, vol.36
, pp. 2519-2530
-
-
Grune, T.1
Jung, T.2
Merker, K.3
Davies, K.J.4
-
22
-
-
77049308856
-
Aging: a theory based on free radical and radiation chemistry
-
Harman D (1956) Aging: a theory based on free radical and radiation chemistry. J Gerontol. 11, 298-300.
-
(1956)
J Gerontol.
, vol.11
, pp. 298-300
-
-
Harman, D.1
-
23
-
-
33646744719
-
Elimination of damaged proteins during differentiation of embryonic stem cells
-
Hernebring M, Brolen G, Aguilaniu H, Semb H, Nystrom T (2006) Elimination of damaged proteins during differentiation of embryonic stem cells. Proc. Natl. Acad. Sci. U S A 103, 7700-7705.
-
(2006)
Proc. Natl. Acad. Sci. U S A
, vol.103
, pp. 7700-7705
-
-
Hernebring, M.1
Brolen, G.2
Aguilaniu, H.3
Semb, H.4
Nystrom, T.5
-
24
-
-
0037108212
-
Protein oxidation during aging of the nematode Caenorhabditis elegans
-
Ishii N, Goto S, Hartman PS (2002) Protein oxidation during aging of the nematode Caenorhabditis elegans. Free Radic. Biol. Med. 33, 1021-1025.
-
(2002)
Free Radic. Biol. Med.
, vol.33
, pp. 1021-1025
-
-
Ishii, N.1
Goto, S.2
Hartman, P.S.3
-
25
-
-
2642571107
-
Oocyte production and sperm utilization patterns in semi-fertile strains of Caenorhabditis elegans
-
Kadandale P, Singson A (2004) Oocyte production and sperm utilization patterns in semi-fertile strains of Caenorhabditis elegans. BMC Dev. Biol. 4, 3.
-
(2004)
BMC Dev. Biol.
, vol.4
, pp. 3
-
-
Kadandale, P.1
Singson, A.2
-
26
-
-
33749185898
-
Autophagy as a cell-repair mechanism: activation of chaperone-mediated autophagy during oxidative stress
-
Kaushik S, Cuervo AM (2006) Autophagy as a cell-repair mechanism: activation of chaperone-mediated autophagy during oxidative stress. Mol. Aspects Med. 27, 444-454.
-
(2006)
Mol. Aspects Med.
, vol.27
, pp. 444-454
-
-
Kaushik, S.1
Cuervo, A.M.2
-
27
-
-
0027771804
-
A C. elegans mutant that lives twice as long as wild type
-
Kenyon C, Chang J, Gensch E, Rudner A, Tabtiang R (1993) A C. elegans mutant that lives twice as long as wild type. Nature 366, 461-464.
-
(1993)
Nature
, vol.366
, pp. 461-464
-
-
Kenyon, C.1
Chang, J.2
Gensch, E.3
Rudner, A.4
Tabtiang, R.5
-
28
-
-
0020724305
-
Tissue-specific synthesis of yolk proteins in Caenorhabditis elegans
-
Kimble J, Sharrock WJ (1983) Tissue-specific synthesis of yolk proteins in Caenorhabditis elegans. Dev. Biol. 96, 189-196.
-
(1983)
Dev. Biol.
, vol.96
, pp. 189-196
-
-
Kimble, J.1
Sharrock, W.J.2
-
29
-
-
0036569401
-
Carbonyl modified proteins in cellular regulation, aging, and disease
-
Levine RL (2002) Carbonyl modified proteins in cellular regulation, aging, and disease. Free Radic. Biol. Med. 32, 790-796.
-
(2002)
Free Radic. Biol. Med.
, vol.32
, pp. 790-796
-
-
Levine, R.L.1
-
30
-
-
0028291974
-
Carbonyl assays for determination of oxidatively modified proteins
-
Levine RL, Williams JA, Stadtman ER, Shacter E (1994) Carbonyl assays for determination of oxidatively modified proteins. Methods Enzymol. 233, 346-357.
-
(1994)
Methods Enzymol.
, vol.233
, pp. 346-357
-
-
Levine, R.L.1
Williams, J.A.2
Stadtman, E.R.3
Shacter, E.4
-
31
-
-
74549184412
-
The polarisome is required for segregation and retrograde transport of protein aggregates
-
Liu B, Larsson L, Caballero A, Hao X, Oling D, Grantham J, Nystrom T (2010) The polarisome is required for segregation and retrograde transport of protein aggregates. Cell 140, 257-267.
-
(2010)
Cell
, vol.140
, pp. 257-267
-
-
Liu, B.1
Larsson, L.2
Caballero, A.3
Hao, X.4
Oling, D.5
Grantham, J.6
Nystrom, T.7
-
32
-
-
13944249618
-
DNA repair, genome stability, and aging
-
Lombard DB, Chua KF, Mostoslavsky R, Franco S, Gostissa M, Alt FW (2005) DNA repair, genome stability, and aging. Cell 120, 497-512.
-
(2005)
Cell
, vol.120
, pp. 497-512
-
-
Lombard, D.B.1
Chua, K.F.2
Mostoslavsky, R.3
Franco, S.4
Gostissa, M.5
Alt, F.W.6
-
33
-
-
0014410114
-
The reduction of cytochrome c by milk xanthine oxidase
-
McCord JM, Fridovich I (1968) The reduction of cytochrome c by milk xanthine oxidase. J. Biol. Chem. 243, 5753-5760.
-
(1968)
J. Biol. Chem.
, vol.243
, pp. 5753-5760
-
-
McCord, J.M.1
Fridovich, I.2
-
34
-
-
0014691273
-
The utility of superoxide dismutase in studying free radical reactions. I. Radicals generated by the interaction of sulfite, dimethyl sulfoxide, and oxygen
-
McCord JM, Fridovich I (1969) The utility of superoxide dismutase in studying free radical reactions. I. Radicals generated by the interaction of sulfite, dimethyl sulfoxide, and oxygen. J. Biol. Chem. 244, 6056-6063.
-
(1969)
J. Biol. Chem.
, vol.244
, pp. 6056-6063
-
-
McCord, J.M.1
Fridovich, I.2
-
35
-
-
0019785421
-
On the immortality of the germ line: genetic and biochemical mechanism. A review
-
Medvedev ZA (1981) On the immortality of the germ line: genetic and biochemical mechanism. A review. Mech. Ageing Dev. 17, 331-359.
-
(1981)
Mech. Ageing Dev.
, vol.17
, pp. 331-359
-
-
Medvedev, Z.A.1
-
36
-
-
36949083936
-
Coupling of phosphorylation to electron and hydrogen transfer by a chemi-osmotic type of mechanism
-
Mitchell P (1961) Coupling of phosphorylation to electron and hydrogen transfer by a chemi-osmotic type of mechanism. Nature 191, 144-148.
-
(1961)
Nature
, vol.191
, pp. 144-148
-
-
Mitchell, P.1
-
37
-
-
0033595808
-
Vitellogenin-6 is a major carbonylated protein in aged nematode, Caenorhabditis elegans
-
Nakamura A, Yasuda K, Adachi H, Sakurai Y, Ishii N, Goto S (1999) Vitellogenin-6 is a major carbonylated protein in aged nematode, Caenorhabditis elegans. Biochem. Biophys. Res. Commun. 264, 580-583.
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.264
, pp. 580-583
-
-
Nakamura, A.1
Yasuda, K.2
Adachi, H.3
Sakurai, Y.4
Ishii, N.5
Goto, S.6
-
38
-
-
0028220114
-
Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster
-
Orr WC, Sohal RS (1994) Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster. Science 263, 1128-1130.
-
(1994)
Science
, vol.263
, pp. 1128-1130
-
-
Orr, W.C.1
Sohal, R.S.2
-
39
-
-
33750719563
-
Maintenance of proteins and aging: the role of oxidized protein repair
-
Petropoulos I, Friguet B (2006) Maintenance of proteins and aging: the role of oxidized protein repair. Free Radic. Res. 40, 1269-1276.
-
(2006)
Free Radic. Res.
, vol.40
, pp. 1269-1276
-
-
Petropoulos, I.1
Friguet, B.2
-
40
-
-
0029928581
-
Single-cell investigation by laser scanning confocal microscopy of cytochemical alterations resulting from extracellular oxidant challenge
-
Pompella A, Cambiaggi C, Dominici S, Paolicchi A, Tongiani R, Comporti M (1996) Single-cell investigation by laser scanning confocal microscopy of cytochemical alterations resulting from extracellular oxidant challenge. Histochem. Cell Biol. 105, 173-178.
-
(1996)
Histochem. Cell Biol.
, vol.105
, pp. 173-178
-
-
Pompella, A.1
Cambiaggi, C.2
Dominici, S.3
Paolicchi, A.4
Tongiani, R.5
Comporti, M.6
-
41
-
-
70449133798
-
Redox control of the cell cycle in health and disease
-
Sarsour EH, Kumar MG, Chaudhuri L, Kalen AL, Goswami PC (2009) Redox control of the cell cycle in health and disease. Antioxid. Redox Signal. 11, 2985-3011.
-
(2009)
Antioxid. Redox Signal.
, vol.11
, pp. 2985-3011
-
-
Sarsour, E.H.1
Kumar, M.G.2
Chaudhuri, L.3
Kalen, A.L.4
Goswami, P.C.5
-
42
-
-
0345600235
-
Redox regulation of germline and vulval development in Caenorhabditis elegans
-
Shibata Y, Branicky R, Landaverde IO, Hekimi S (2003) Redox regulation of germline and vulval development in Caenorhabditis elegans. Science 302, 1779-1782.
-
(2003)
Science
, vol.302
, pp. 1779-1782
-
-
Shibata, Y.1
Branicky, R.2
Landaverde, I.O.3
Hekimi, S.4
-
43
-
-
0035900651
-
On the role of RNA amplification in dsRNA-triggered gene silencing
-
Sijen T, Fleenor J, Simmer F, Thijssen KL, Parrish S, Timmons L, Plasterk RH, Fire A (2001) On the role of RNA amplification in dsRNA-triggered gene silencing. Cell 107, 465-476.
-
(2001)
Cell
, vol.107
, pp. 465-476
-
-
Sijen, T.1
Fleenor, J.2
Simmer, F.3
Thijssen, K.L.4
Parrish, S.5
Timmons, L.6
Plasterk, R.H.7
Fire, A.8
-
44
-
-
0026795635
-
Protein oxidation and aging
-
Stadtman ER (1992) Protein oxidation and aging. Science 257, 1220-1224.
-
(1992)
Science
, vol.257
, pp. 1220-1224
-
-
Stadtman, E.R.1
-
46
-
-
38949091096
-
Strong purifying selection in transmission of mammalian mitochondrial DNA
-
Stewart JB, Freyer C, Elson JL, Wredenberg A, Cansu Z, Trifunovic A, Larsson NG (2008) Strong purifying selection in transmission of mammalian mitochondrial DNA. PLoS Biol. 6, e10.
-
(2008)
PLoS Biol.
, vol.6
-
-
Stewart, J.B.1
Freyer, C.2
Elson, J.L.3
Wredenberg, A.4
Cansu, Z.5
Trifunovic, A.6
Larsson, N.G.7
-
47
-
-
0030881686
-
Oxidative damage during aging targets mitochondrial aconitase
-
Yan LJ, Levine RL, Sohal RS (1997) Oxidative damage during aging targets mitochondrial aconitase. Proc. Natl. Acad. Sci. U S A 94, 11168-11172.
-
(1997)
Proc. Natl. Acad. Sci. U S A
, vol.94
, pp. 11168-11172
-
-
Yan, L.J.1
Levine, R.L.2
Sohal, R.S.3
|