메뉴 건너뛰기




Volumn , Issue 30, 2010, Pages 5767-5771

A highly stereoselective total synthesis of (+)-9-epi-dictyostatin

Author keywords

Antitumor agents; Asymmetric synthesis; Macrocycles; Natural products; Total synthesis

Indexed keywords


EID: 78249255833     PISSN: 1434193X     EISSN: 10990690     Source Type: Journal    
DOI: 10.1002/ejoc.201001018     Document Type: Article
Times cited : (9)

References (55)
  • 48
    • 0000693499 scopus 로고
    • and references cited therein.
    • I. Paterson, A. Schlapbach, Synlett 1995, 498-500 and references cited therein.
    • (1995) Synlett , pp. 498-500
    • Paterson, I.1    Schlapbach, A.2
  • 49
    • 0030772544 scopus 로고    scopus 로고
    • The compatibility of a terminal (Z)-vinyl iodide with the installation (modified Peterson olefination) of the terminal (Z)-diene had previously been demonstrated in the total synthesis of(-)-discodermolide, see:
    • The compatibility of a terminal (Z)-vinyl iodide with the installation (modified Peterson olefination) of the terminal (Z)-diene had previously been demonstrated in the total synthesis of(-)-discodermolide, see:, S. S. Harried, G. Yang, M. A. Strawn, D. C. Myles, J. Org. Chem. 1997, 62, 6098 - 6099.
    • (1997) J. Org. Chem. , vol.62 , pp. 6098-6099
    • Harried, S.S.1    Yang, G.2    Strawn, M.A.3    Myles, D.C.4
  • 51
    • 78249240286 scopus 로고    scopus 로고
    • The crude reaction mixture was purified by flash chromatography to give, in order of elution: de-iodinated alkene, coupling product 18, and unreacted aldehyde 2. See the Supporting Information for details.
    • The crude reaction mixture was purified by flash chromatography to give, in order of elution: de-iodinated alkene, coupling product 18, and unreacted aldehyde 2. See the Supporting Information for details.
  • 54
    • 77950255039 scopus 로고    scopus 로고
    • Reactions of (Z)-disubstituted vinylzinc reagents with α-OTBS substituted aldehydes, in the presence of added RZnX (1.5 equiv.), have been shown to proceed through a Cram-chelation mechanism, see:
    • Reactions of (Z)-disubstituted vinylzinc reagents with α-OTBS substituted aldehydes, in the presence of added RZnX (1.5 equiv.), have been shown to proceed through a Cram-chelation mechanism, see:, G. R. Stanton, C. N. Johnson, P. G. Walsh, J. Am. Chem. Soc. 2010, 132, 4399 - 4408.
    • (2010) J. Am. Chem. Soc. , vol.132 , pp. 4399-4408
    • Stanton, G.R.1    Johnson, C.N.2    Walsh, P.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.