Solution structure, mechanism of replication, and optimization of an unnatural base pair

Chemistry - A European Journal

Volumn 16, Issue 42, 2010, Pages 12650-12659

  Malyshev, Denis A ^a   Pfaff, Danielle A ^b   Ippoliti, Shannon I ^b   Hwang, Gil Tae ^a,c   Dwyer, Tammy J ^b   Romesberg, Floyd E ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF SAN DIEGO   (United States)

^c Kyungpook National University   (South Korea)

Author keywords

DNA replication; genetic alphabet; intercalations; polymerase; unnatural base pairs

Indexed keywords

BASE PAIRS; DNA POLYMERASE; DNA REPLICATIONS; DUPLEX DNA; FURAN RING; GENETIC ALPHABET; IN-VITRO; IN-VIVO; METHOXY; NUCLEOTIDE ANALOGUES; PCR AMPLIFICATION; POLYMERASE; SOLUTION STRUCTURES; STRUCTURE ACTIVITY RELATIONSHIPS; SYNTHESIS AND CHARACTERIZATIONS; UNNATURAL BASE PAIRS;

DNA; NUCLEOTIDES; OPTIMIZATION; POLYMERS;

POLYMERASE CHAIN REACTION;

ANTISENSE OLIGONUCLEOTIDE; DNA; DNA DIRECTED DNA POLYMERASE;

ARTICLE; BASE PAIRING; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; DNA REPLICATION; METABOLISM; MOLECULAR GENETICS; NUCLEAR MAGNETIC RESONANCE; SEQUENCE HOMOLOGY; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

BASE PAIRING; DNA; DNA REPLICATION; DNA-DIRECTED DNA POLYMERASE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; NUCLEIC ACID CONFORMATION; OLIGORIBONUCLEOTIDES, ANTISENSE; SEQUENCE HOMOLOGY, NUCLEIC ACID; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 78249251747     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.201000959     Document Type: Article

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