-
1
-
-
56749184290
-
Insulin and insulin-like growth factor signalling in neoplasia
-
Pollak M. Insulin and insulin-like growth factor signalling in neoplasia. Nat Rev Cancer 2008; 8: 915-928.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 915-928
-
-
Pollak, M.1
-
2
-
-
0027303072
-
Insulin and IGF-1 increase mitogenesis and glucose metabolism in the multiple myeloma cell line, RPMI-8226
-
Freund GG, Kulas DT, Mooney RA. Insulin and IGF-1 increase mitogenesis and glucose metabolism in the multiple myeloma cell line, RPMI-8226. J Immunol 1993; 151: 1811-1820.
-
(1993)
J Immunol
, vol.151
, pp. 1811-1820
-
-
Freund, G.G.1
Kulas, D.T.2
Mooney, R.A.3
-
3
-
-
33645315222
-
Microarray-based understanding of normal and malignant plasma cells
-
De Vos J, Hose D, Reme T, Moreaux J, Mahtouk K, Jourdan M et al. Microarray-based understanding of normal and malignant plasma cells. Immunol Rev 2006; 210: 86-104.
-
(2006)
Immunol Rev
, vol.210
, pp. 86-104
-
-
De Vos, J.1
Hose, D.2
Reme, T.3
Moreaux, J.4
Mahtouk, K.5
Jourdan, M.6
-
4
-
-
66549106493
-
The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor
-
Sprynski AC, Hose D, Caillot L, Reme T, Shaughnessy Jr JD, Barlogie B et al. The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor. Blood 2009; 113: 4614-4626.
-
(2009)
Blood
, vol.113
, pp. 4614-4626
-
-
Sprynski, A.C.1
Hose, D.2
Caillot, L.3
Reme, T.4
Shaughnessy Jr., J.D.5
Barlogie, B.6
-
5
-
-
20344393906
-
CD221 (IGF-1R) is aberrantly expressed in multiple myeloma, in relation to disease severity
-
Bataille R, Robillard N, Avet-Loiseau H, Harousseau JL, Moreau P. CD221 (IGF-1R) is aberrantly expressed in multiple myeloma, in relation to disease severity. Haematologica 2005; 90: 706-707.
-
(2005)
Haematologica
, vol.90
, pp. 706-707
-
-
Bataille, R.1
Robillard, N.2
Avet-Loiseau, H.3
Harousseau, J.L.4
Moreau, P.5
-
6
-
-
33644976163
-
IGF-1R is overexpressed in poor-prognostic subtypes of multiple myeloma
-
Chng WJ, Gualberto A, Fonseca R. IGF-1R is overexpressed in poor-prognostic subtypes of multiple myeloma. Leukemia 2006; 20: 174-176.
-
(2006)
Leukemia
, vol.20
, pp. 174-176
-
-
Chng, W.J.1
Gualberto, A.2
Fonseca, R.3
-
7
-
-
0036782071
-
Structural biology of insulin and IGF1 receptors: Implications for drug design
-
De Meyts P, Whittaker J. Structural biology of insulin and IGF1 receptors: implications for drug design. Nat Rev Drug Discov 2002; 1: 769-783.
-
(2002)
Nat Rev Drug Discov
, vol.1
, pp. 769-783
-
-
De Meyts, P.1
Whittaker, J.2
-
8
-
-
0037131385
-
Insulin/insulin-like growth factor i hybrid receptors have different biological characteristics depending on the insulin receptor isoform involved
-
Pandini G, Frasca F, Mineo R, Sciacca L, Vigneri R, Belfiore A. Insulin/insulin-like growth factor I hybrid receptors have different biological characteristics depending on the insulin receptor isoform involved. J Biol Chem 2002; 277: 39684-39695.
-
(2002)
J Biol Chem
, vol.277
, pp. 39684-39695
-
-
Pandini, G.1
Frasca, F.2
Mineo, R.3
Sciacca, L.4
Vigneri, R.5
Belfiore, A.6
-
9
-
-
33748744723
-
Hybrid receptors formed by insulin receptor (IR) and insulin-like growth factor i receptor (IGF-IR) have low insulin and high IGF-1 affinity irrespective of the IR splice variant
-
Slaaby R, Schaffer L, Lautrup-Larsen I, Andersen AS, Shaw AC, Mathiasen IS et al. Hybrid receptors formed by insulin receptor (IR) and insulin-like growth factor I receptor (IGF-IR) have low insulin and high IGF-1 affinity irrespective of the IR splice variant. J Biol Chem 2006; 281: 25869-25874.
-
(2006)
J Biol Chem
, vol.281
, pp. 25869-25874
-
-
Slaaby, R.1
Schaffer, L.2
Lautrup-Larsen, I.3
Andersen, A.S.4
Shaw, A.C.5
Mathiasen, I.S.6
-
10
-
-
0028282852
-
Reproducible obtaining of human myeloma cell lines as a model for tumor stem cell study in human multiple myeloma
-
Zhang XG, Gaillard JP, Robillard N, Lu ZY, Gu ZJ, Jourdan M et al. Reproducible obtaining of human myeloma cell lines as a model for tumor stem cell study in human multiple myeloma. Blood 1994; 83: 3654-3663.
-
(1994)
Blood
, vol.83
, pp. 3654-3663
-
-
Zhang, X.G.1
Gaillard, J.P.2
Robillard, N.3
Lu, Z.Y.4
Gu, Z.J.5
Jourdan, M.6
-
11
-
-
73949109704
-
An in vitro model of differentiation of memory B cells into plasmablasts and plasma cells including detailed phenotypic and molecular characterization
-
Jourdan M, Caraux A, De Vos J, Fiol G, Larroque M, Cognot C et al. An in vitro model of differentiation of memory B cells into plasmablasts and plasma cells including detailed phenotypic and molecular characterization. Blood 2009; 114: 5173-5181.
-
(2009)
Blood
, vol.114
, pp. 5173-5181
-
-
Jourdan, M.1
Caraux, A.2
De Vos, J.3
Fiol, G.4
Larroque, M.5
Cognot, C.6
-
12
-
-
1442332300
-
An inhibitor of the EGF receptor family blocks myeloma cell growth factor activity of HB-EGF and potentiates dexamethasone or anti-IL-6 antibody-induced apoptosis
-
Mahtouk K, Jourdan M, De Vos J, Hertogh C, Fiol G, Jourdan E et al. An inhibitor of the EGF receptor family blocks myeloma cell growth factor activity of HB-EGF and potentiates dexamethasone or anti-IL-6 antibody-induced apoptosis. Blood 2004; 103: 1829-1837.
-
(2004)
Blood
, vol.103
, pp. 1829-1837
-
-
Mahtouk, K.1
Jourdan, M.2
De Vos, J.3
Hertogh, C.4
Fiol, G.5
Jourdan, E.6
-
13
-
-
0025942846
-
Human recombinant dimeric IL-6 binds to its receptor as detected by anti-IL-6 monoclonal antibodies
-
Wijdenes J, Clement C, Klein B, Morel-Fourrier B, VIta N, Ferrara P et al. Human recombinant dimeric IL-6 binds to its receptor as detected by anti-IL-6 monoclonal antibodies. Mol Immunol 1991; 28: 1183.
-
(1991)
Mol Immunol
, vol.28
, pp. 1183
-
-
Wijdenes, J.1
Clement, C.2
Klein, B.3
Morel-Fourrier, B.4
Vita, N.5
Ferrara, P.6
-
14
-
-
12144285705
-
In vivo antitumor activity of NVP-AEW541-A novel, potent, and selective inhibitor of the IGF-IR kinase
-
Garcia-Echeverria C, Pearson MA, Marti A, Meyer T, Mestan J, Zimmermann J et al. In vivo antitumor activity of NVP-AEW541-A novel, potent, and selective inhibitor of the IGF-IR kinase. Cancer Cell 2004; 5: 231-239.
-
(2004)
Cancer Cell
, vol.5
, pp. 231-239
-
-
Garcia-Echeverria, C.1
Pearson, M.A.2
Marti, A.3
Meyer, T.4
Mestan, J.5
Zimmermann, J.6
-
15
-
-
33751168727
-
Insulin and IGF-I action on insulin receptors, IGF-I receptors, and hybrid insulin/IGF-I receptors in vascular smooth muscle cells
-
Johansson GS, Arnqvist HJ. Insulin and IGF-I action on insulin receptors, IGF-I receptors, and hybrid insulin/IGF-I receptors in vascular smooth muscle cells. Am J Physiol Endocrinol Metab 2006; 291: E1124-E1130.
-
(2006)
Am J Physiol Endocrinol Metab
, vol.291
-
-
Johansson, G.S.1
Arnqvist, H.J.2
-
16
-
-
21144474918
-
Expression of EGF-family receptors and amphiregulin in multiple myeloma. Amphiregulin is a growth factor for myeloma cells
-
Mahtouk K, Hose D, Reme T, De Vos J, Jourdan M, Moreaux J et al. Expression of EGF-family receptors and amphiregulin in multiple myeloma. Amphiregulin is a growth factor for myeloma cells. Oncogene 2005; 24: 3512-3524.
-
(2005)
Oncogene
, vol.24
, pp. 3512-3524
-
-
Mahtouk, K.1
Hose, D.2
Reme, T.3
De Vos, J.4
Jourdan, M.5
Moreaux, J.6
-
17
-
-
0031929051
-
The myeloma cell antigen syndecan-1 is lost by apoptotic myeloma cells
-
Michel J, Martine F, Eric L, Mira H, Janny L, Jean FranÇ ois R et al. The myeloma cell antigen syndecan-1 is lost by apoptotic myeloma cells. Br J Haematol 1998; 100: 637-646.
-
(1998)
Br J Haematol
, vol.100
, pp. 637-646
-
-
Michel, J.1
Martine, F.2
Eric, L.3
Mira, H.4
Janny, L.5
Jean François, R.6
-
18
-
-
43549125507
-
A new method for class prediction based on signed-rank algorithms applied to Affymetrix microarray experiments
-
Reme T, Hose D, De Vos J, Vassal A, Poulain PO, Pantesco V et al. A new method for class prediction based on signed-rank algorithms applied to Affymetrix microarray experiments. BMC Bioinformatics 2008; 9: 16.
-
(2008)
BMC Bioinformatics
, vol.9
, pp. 16
-
-
Reme, T.1
Hose, D.2
De Vos, J.3
Vassal, A.4
Poulain, P.O.5
Pantesco, V.6
-
19
-
-
34147113900
-
A meta-analysis of human embryonic stem cells transcrip-tome integrated into a web-based expression atlas
-
Assou S, Le Carrour T, Tondeur S, Strom S, Gabelle A, Marty S et al. A meta-analysis of human embryonic stem cells transcrip-tome integrated into a web-based expression atlas. Stem Cells 2007; 25: 961-973.
-
(2007)
Stem Cells
, vol.25
, pp. 961-973
-
-
Assou, S.1
Le Carrour, T.2
Tondeur, S.3
Strom, S.4
Gabelle, A.5
Marty, S.6
-
20
-
-
34547660308
-
Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma
-
Keats JJ, Fonseca R, Chesi M, Schop R, Baker A, Chng WJ et al. Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma. Cancer Cell 2007; 12: 131-144.
-
(2007)
Cancer Cell
, vol.12
, pp. 131-144
-
-
Keats, J.J.1
Fonseca, R.2
Chesi, M.3
Schop, R.4
Baker, A.5
Chng, W.J.6
-
21
-
-
34547562418
-
Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma
-
Annunziata CM, Davis RE, Demchenko Y, Bellamy W, Gabrea A, Zhan F et al. Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma. Cancer Cell 2007; 12: 115-130.
-
(2007)
Cancer Cell
, vol.12
, pp. 115-130
-
-
Annunziata, C.M.1
Davis, R.E.2
Demchenko, Y.3
Bellamy, W.4
Gabrea, A.5
Zhan, F.6
-
22
-
-
77951719556
-
Classical and/or alternative NF-{kappa}B pathway activation in multiple myeloma
-
Demchenko YN, Glebov OK, Zingone A, Keats JJ, Bergsagel PL, Kuehl WM. Classical and/or alternative NF-{kappa}B pathway activation in multiple myeloma. Blood 2010; 115: 3541-3552.
-
(2010)
Blood
, vol.115
, pp. 3541-3552
-
-
Demchenko, Y.N.1
Glebov, O.K.2
Zingone, A.3
Keats, J.J.4
Bergsagel, P.L.5
Kuehl, W.M.6
-
23
-
-
52149094341
-
Characterization of MYC translocations in multiple myeloma cell lines
-
Dib A, Gabrea A, Glebov OK, Bergsagel PL, Kuehl WM. Characterization of MYC translocations in multiple myeloma cell lines. J Natl Cancer Inst Monogr 2008; 39: 25-31.
-
(2008)
J Natl Cancer Inst Monogr
, vol.39
, pp. 25-31
-
-
Dib, A.1
Gabrea, A.2
Glebov, O.K.3
Bergsagel, P.L.4
Kuehl, W.M.5
-
24
-
-
0034669945
-
Loss of PTEN expression leading to high Akt activation in human multiple myelomas
-
Hyun T, Yam A, Pece S, Xie X, Zhang J, Miki T et al. Loss of PTEN expression leading to high Akt activation in human multiple myelomas. Blood 2000; 96: 3560-3568.
-
(2000)
Blood
, vol.96
, pp. 3560-3568
-
-
Hyun, T.1
Yam, A.2
Pece, S.3
Xie, X.4
Zhang, J.5
Miki, T.6
-
25
-
-
0346095210
-
The insulin receptor isoform exon 11- (IR-A) in cancer and other diseases: A review
-
Denley A, Wallace JC, Cosgrove LJ, Forbes BE. The insulin receptor isoform exon 11- (IR-A) in cancer and other diseases: a review. Horm Metab Res 2003; 35: 778-785.
-
(2003)
Horm Metab Res
, vol.35
, pp. 778-785
-
-
Denley, A.1
Wallace, J.C.2
Cosgrove, L.J.3
Forbes, B.E.4
-
26
-
-
22544478497
-
Molecular interactions of the IGF system
-
Denley A, Cosgrove LJ, Booker GW, Wallace JC, Forbes BE. Molecular interactions of the IGF system. Cytokine Growth Factor Rev 2005; 16: 421-439.
-
(2005)
Cytokine Growth Factor Rev
, vol.16
, pp. 421-439
-
-
Denley, A.1
Cosgrove, L.J.2
Booker, G.W.3
Wallace, J.C.4
Forbes, B.E.5
-
27
-
-
0032800850
-
Insulin and insulin-like growth factor-I (IGF-I) receptor overexpression in breast cancers leads to insulin/IGF-I hybrid receptor overexpression: Evidence for a second mechanism of IGF-I signaling
-
Pandini G, Vigneri R, Costantino A, Frasca F, Ippolito A, Fujita-Yamaguchi Y et al. Insulin and insulin-like growth factor-I (IGF-I) receptor overexpression in breast cancers leads to insulin/IGF-I hybrid receptor overexpression: evidence for a second mechanism of IGF-I signaling. Clin Cancer Res 1999; 5: 1935-1944.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 1935-1944
-
-
Pandini, G.1
Vigneri, R.2
Costantino, A.3
Frasca, F.4
Ippolito, A.5
Fujita-Yamaguchi, Y.6
-
28
-
-
34248170187
-
Functional responses and in vivo anti-tumour activity of h7C10: A humanised monoclonal antibody with neutralising activity against the insulin-like growth factor-1 (IGF-1) receptor and insulin/IGF-1 hybrid receptors
-
Pandini G, Wurch T, Akla B, Corvaia N, Belfiore A, Goetsch L. Functional responses and in vivo anti-tumour activity of h7C10: a humanised monoclonal antibody with neutralising activity against the insulin-like growth factor-1 (IGF-1) receptor and insulin/IGF-1 hybrid receptors. Eur J Cancer 2007; 43: 1318-1327.
-
(2007)
Eur J Cancer
, vol.43
, pp. 1318-1327
-
-
Pandini, G.1
Wurch, T.2
Akla, B.3
Corvaia, N.4
Belfiore, A.5
Goetsch, L.6
-
29
-
-
67649111278
-
Expression of genes encoding for proteins involved in heparan sulphate and chondroitin sulphate chain synthesis and modification in normal and malignant plasma cells
-
Bret C, Hose D, Reme T, Sprynski AC, Mahtouk K, Schved JF et al. Expression of genes encoding for proteins involved in heparan sulphate and chondroitin sulphate chain synthesis and modification in normal and malignant plasma cells. Br J Haematol 2009; 145: 350-368.
-
(2009)
Br J Haematol
, vol.145
, pp. 350-368
-
-
Bret, C.1
Hose, D.2
Reme, T.3
Sprynski, A.C.4
Mahtouk, K.5
Schved, J.F.6
-
30
-
-
33244464562
-
Critical nodes in signalling pathways: Insights into insulin action
-
Taniguchi CM, Emanuelli B, Kahn CR. Critical nodes in signalling pathways: insights into insulin action. Nat Rev Mol Cell Biol 2006; 7: 85-96.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 85-96
-
-
Taniguchi, C.M.1
Emanuelli, B.2
Kahn, C.R.3
-
31
-
-
78149470373
-
Osteoclast gene expression profiling in multiple myeloma
-
Moreaux J, Hose D, Reme T, Moine P, Mahtouk K, Moos M et al. Osteoclast gene expression profiling in multiple myeloma. Blood 2008; 112: 945.
-
(2008)
Blood
, vol.112
, pp. 945
-
-
Moreaux, J.1
Hose, D.2
Reme, T.3
Moine, P.4
Mahtouk, K.5
Moos, M.6
-
32
-
-
0037464510
-
Overweight, obesity, and mortality from cancer in a prospectively studied cohort of US adults
-
Calle EE, Rodriguez C, Walker-Thurmond K, Thun MJ. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of US adults. N Engl J Med 2003; 348: 1625-1638.
-
(2003)
N Engl J Med
, vol.348
, pp. 1625-1638
-
-
Calle, E.E.1
Rodriguez, C.2
Walker-Thurmond, K.3
Thun, M.J.4
-
33
-
-
54349083481
-
Prediagnostic body-mass index, plasma C-peptide concentration, and prostate cancer-specific mortality in men with prostate cancer: A long-term survival analysis
-
Ma J, Li H, Giovannucci E, Mucci L, Qiu W, Nguyen PL et al. Prediagnostic body-mass index, plasma C-peptide concentration, and prostate cancer-specific mortality in men with prostate cancer: a long-term survival analysis. Lancet Oncol 2008; 9: 1039-1047.
-
(2008)
Lancet Oncol
, vol.9
, pp. 1039-1047
-
-
Ma, J.1
Li, H.2
Giovannucci, E.3
Mucci, L.4
Qiu, W.5
Nguyen, P.L.6
-
34
-
-
0036138579
-
Fasting insulin and outcome in early-stage breast cancer: Results of a prospective cohort study
-
Goodwin PJ, Ennis M, Pritchard KI, Trudeau ME, Koo J, Madarnas Y et al. Fasting insulin and outcome in early-stage breast cancer: results of a prospective cohort study. J Clin Oncol 2002; 20: 42-51.
-
(2002)
J Clin Oncol
, vol.20
, pp. 42-51
-
-
Goodwin, P.J.1
Ennis, M.2
Pritchard, K.I.3
Trudeau, M.E.4
Koo, J.5
Madarnas, Y.6
-
35
-
-
23744441489
-
Type 2 diabetes mellitus, its treatment and risk for lymphoma
-
Fortuny J, Benavente Y, Bosch R, Garcia-Villanueva M, de Sevilla AF, de Sanjose S. Type 2 diabetes mellitus, its treatment and risk for lymphoma. Eur J Cancer 2005; 41: 1782-1787.
-
(2005)
Eur J Cancer
, vol.41
, pp. 1782-1787
-
-
Fortuny, J.1
Benavente, Y.2
Bosch, R.3
Garcia-Villanueva, M.4
De Sevilla, A.F.5
De Sanjose, S.6
-
36
-
-
33645766204
-
Increased cancer-related mortality for patients with type 2 diabetes who use sulfonylureas or insulin
-
Bowker SL, Majumdar SR, Veugelers P, Johnson JA. Increased cancer-related mortality for patients with type 2 diabetes who use sulfonylureas or insulin. Diabetes Care 2006; 29: 254-258.
-
(2006)
Diabetes Care
, vol.29
, pp. 254-258
-
-
Bowker, S.L.1
Majumdar, S.R.2
Veugelers, P.3
Johnson, J.A.4
|