Gene network analysis of bone marrow mononuclear cells reveals activation of multiple kinase pathways in human systemic lupus erythematosus

PLoS ONE

Volumn 5, Issue 10, 2010, Pages

  Nakou, Magdalene ^a   Bertsias, George ^a,b   Stagakis, Ilias ^a,b   Centola, Michael ^c   Tassiulas, Ioannis ^a,b   Hatziapostolou, Maria ^d,e   Kritikos, Iraklis ^a   Goulielmos, George ^a   Boumpas, Dimitrios T ^a,b   Iliopoulos, Dimitrios ^d,e  

^a UNIVERSITY OF CRETE   (Greece)

^b INSTITUTE OF MOLECULAR BIOLOGY AND BIOTECHNOLOGY   (Greece)

^c OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

^d DANA FARBER CANCER INSTITUTE   (United States)

^e HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA2 INTEGRIN; CALCIUM CHANNEL; HEAT SHOCK PROTEIN 27; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P32; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE C; STAT3 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR FKHRL1; UNCLASSIFIED DRUG; VITAMIN D RECEPTOR; COMPLEMENTARY DNA; PRIMER DNA; PROTEIN KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; C57BL 6 MOUSE; CLINICAL ASSESSMENT TOOL; CONTROLLED STUDY; DISEASE ACTIVITY; DOWN REGULATION; ENZYME ACTIVATION; FEMALE; GENE CONSTRUCT; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; GENE REGULATORY NETWORK; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MONONUCLEAR CELL; MOUSE; NEW ZEALAND BLACK MOUSE; NONHODGKIN LYMPHOMA; NONHUMAN; PATHOGENESIS; PROTEIN MICROARRAY; PROTEIN PROCESSING; PROTEIN TARGETING; SIGNAL TRANSDUCTION; SYSTEMIC LUPUS ERYTHEMATOSUS; WESTERN BLOTTING; ANIMAL; DNA MICROARRAY; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYMOLOGY; GENETICS; METABOLISM; NUCLEOTIDE SEQUENCE;

MUS;

ANIMALS; BASE SEQUENCE; BONE MARROW CELLS; DNA PRIMERS; DNA, COMPLEMENTARY; ENZYME ACTIVATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE REGULATORY NETWORKS; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MICE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEIN KINASES; RNA, MESSENGER;

EID: 78149457487     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0013351     Document Type: Article

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