-
1
-
-
32144454172
-
The Many Roles of Chemokines and Chemokine Receptors in Inflammation
-
Charo IF, Ransohoff RM (2006) The Many Roles of Chemokines and Chemokine Receptors in Inflammation. N Engl J Med 354: 610-621.
-
(2006)
N Engl J Med
, vol.354
, pp. 610-621
-
-
Charo, I.F.1
Ransohoff, R.M.2
-
2
-
-
0037180768
-
The immunopathogenesis of sepsis
-
Cohen J (2002) The immunopathogenesis of sepsis. Nature 420: 885-891.
-
(2002)
Nature
, vol.420
, pp. 885-891
-
-
Cohen, J.1
-
3
-
-
0035826096
-
Efficacy and Safety of Recombinant Human Activated Protein C for Severe Sepsis
-
Bernard GR, Vincent J-L, Laterre P-F, LaRosa SP, Dhainaut J-F, et al. (2001) Efficacy and Safety of Recombinant Human Activated Protein C for Severe Sepsis. N Engl J Med 344: 699-709.
-
(2001)
N Engl J Med
, vol.344
, pp. 699-709
-
-
Bernard, G.R.1
Vincent, J.-L.2
Laterre, P.-F.3
LaRosa, S.P.4
Dhainaut, J.-F.5
-
6
-
-
8144228302
-
Gene Expression Profiling of Inflamed Human Endothelial Cells and Influence of Activated Protein C
-
Franscini N, Bachli EB, Blau N, Leikauf M-S, Schaffner A, et al. (2004) Gene Expression Profiling of Inflamed Human Endothelial Cells and Influence of Activated Protein C. Circulation 110: 2903-2909.
-
(2004)
Circulation
, vol.110
, pp. 2903-2909
-
-
Franscini, N.1
Bachli, E.B.2
Blau, N.3
Leikauf, M.-S.4
Schaffner, A.5
-
7
-
-
26444604781
-
Drotrecogin alfa (activated) treatment in severe sepsis from the global open-label trial ENHANCE: Further evidence for survival and safety and implications for early treatment
-
Vincent J, Bernard G, Beale R, Doig C, Putensen C, et al. (2005) Drotrecogin alfa (activated) treatment in severe sepsis from the global open-label trial ENHANCE: further evidence for survival and safety and implications for early treatment. Critical Care Medicine 33: 2266-2277.
-
(2005)
Critical Care Medicine
, vol.33
, pp. 2266-2277
-
-
Vincent, J.1
Bernard, G.2
Beale, R.3
Doig, C.4
Putensen, C.5
-
8
-
-
77953504483
-
Regulation of the Protein C Anticoagulant and Antiinflammatory Pathways
-
Rezaie AR (2010) Regulation of the Protein C Anticoagulant and Antiinflammatory Pathways. Curr Med Chem 17: 2059-2069.
-
(2010)
Curr Med Chem
, vol.17
, pp. 2059-2069
-
-
Rezaie, A.R.1
-
9
-
-
77953509941
-
Engineering Thrombin for Selective Specificity toward Protein C and PAR1
-
Marino F, Pelc LA, Vogt A, Gandhi PS, Di Cera E (2010) Engineering Thrombin for Selective Specificity toward Protein C and PAR1. Journal of Biological Chemistry 285: 19145-19152.
-
(2010)
Journal of Biological Chemistry
, vol.285
, pp. 19145-19152
-
-
Marino, F.1
Pelc, L.A.2
Vogt, A.3
Gandhi, P.S.4
Di Cera, E.5
-
10
-
-
74949109112
-
Regulation of inflammation by the protein C system
-
10.1097/CCM.1090b1013e3181c1099cbb1095
-
Weiler H (2010) Regulation of inflammation by the protein C system. Critical Care Medicine 38: S18-S25. 10.1097/CCM.1090b1013e3181c1099cbb1095.
-
(2010)
Critical Care Medicine
, vol.38
-
-
Weiler, H.1
-
11
-
-
78149422692
-
Transcriptome analysis of the PAR-1 mediated activation pathway in human monocytes and interactions of Activated Protein C
-
Pereira C, Bachli EB, Schoedon G (2007) Transcriptome analysis of the PAR-1 mediated activation pathway in human monocytes and interactions of Activated Protein C. J Thromb Haemost 5: P-M-090.
-
(2007)
J Thromb Haemost
, vol.5
-
-
Pereira, C.1
Bachli, E.B.2
Schoedon, G.3
-
12
-
-
40749112792
-
Wnt5A/CaMKII Signaling Contributes to the Inflammatory Response of Macrophages and Is a Target for the Antiinflammatory Action of Activated Protein C and Interleukin-10
-
Pereira C, Schaer DJ, Bachli EB, Kurrer MO, Schoedon G (2008) Wnt5A/CaMKII Signaling Contributes to the Inflammatory Response of Macrophages and Is a Target for the Antiinflammatory Action of Activated Protein C and Interleukin-10. Arterioscler Thromb Vasc Biol 28: 504-510.
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, pp. 504-510
-
-
Pereira, C.1
Schaer, D.J.2
Bachli, E.B.3
Kurrer, M.O.4
Schoedon, G.5
-
13
-
-
33846889318
-
Glucocorticoids induce differentiation of a specifically activated, anti-inflammatory subtype of human monocytes
-
Ehrchen J, Steinmuller L, Barczyk K, Tenbrock K, Nacken W, et al. (2007) Glucocorticoids induce differentiation of a specifically activated, anti-inflammatory subtype of human monocytes. Blood 109: 1265-1274.
-
(2007)
Blood
, vol.109
, pp. 1265-1274
-
-
Ehrchen, J.1
Steinmuller, L.2
Barczyk, K.3
Tenbrock, K.4
Nacken, W.5
-
14
-
-
33746888276
-
Modulation of Monocyte Function by Activated Protein C, a Natural Anticoagulant
-
Stephenson DA, Toltl LJ, Beaudin S, Liaw PC (2006) Modulation of Monocyte Function by Activated Protein C, a Natural Anticoagulant. J Immunol 177: 2115-2122.
-
(2006)
J Immunol
, vol.177
, pp. 2115-2122
-
-
Stephenson, D.A.1
Toltl, L.J.2
Beaudin, S.3
Liaw, P.C.4
-
15
-
-
0033880884
-
Activated protein C inhibits lipopolysaccharide-induced nuclear translocation of nuclear factor kB and tumour necrosis factor alpha1 production in the THP-1 monocytic cell line
-
White B, Schmidt M, Murphy C, Livingstone W, O'Toole D, et al. (2000) Activated protein C inhibits lipopolysaccharide-induced nuclear translocation of nuclear factor kB and tumour necrosis factor alpha1 production in the THP-1 monocytic cell line. British Journal of Haematology 110: 130-134.
-
(2000)
British Journal of Haematology
, vol.110
, pp. 130-134
-
-
White, B.1
Schmidt, M.2
Murphy, C.3
Livingstone, W.4
O'Toole, D.5
-
16
-
-
0023280623
-
Similarity of cell-cycle genes of budding yeast and fission yeast and the Notch gene in Drosophila
-
Breeden L, Nasmyth K (1987) Similarity of cell-cycle genes of budding yeast and fission yeast and the Notch gene in Drosophila. Nature 395: 651-654.
-
(1987)
Nature
, vol.395
, pp. 651-654
-
-
Breeden, L.1
Nasmyth, K.2
-
17
-
-
0027374511
-
The membrane-binding domain of ankyrin contains four independently folded subdomains, each comprised of six ankyrin repeats
-
Michaely P, Bennett V (1993) The membrane-binding domain of ankyrin contains four independently folded subdomains, each comprised of six ankyrin repeats. J Biol Chem 268: 22703-22709.
-
(1993)
J Biol Chem
, vol.268
, pp. 22703-22709
-
-
Michaely, P.1
Bennett, V.2
-
18
-
-
0027333330
-
Hundreds of ankyrin-like repeats in functionally diverse proteins: Mobile modules that cross phyla horizontally
-
Bork P (1993) Hundreds of ankyrin-like repeats in functionally diverse proteins: mobile modules that cross phyla horizontally. Proteins 17: 363-374.
-
(1993)
Proteins
, vol.17
, pp. 363-374
-
-
Bork, P.1
-
20
-
-
0034982964
-
Selenium, selenoproteins and human health: A review
-
Brown K, Arthur J (2001) Selenium, selenoproteins and human health: a review. Public Health Nutrition 4: 593-599.
-
(2001)
Public Health Nutrition
, vol.4
, pp. 593-599
-
-
Brown, K.1
Arthur, J.2
-
21
-
-
0030703638
-
Cloning and Characterization of the Human Selenoprotein P Promoter. Response of Selenoprotein P Expression to Cytokynes in Liver Cells
-
Dreher I, Jakobs TC, Kohrle J (1997) Cloning and Characterization of the Human Selenoprotein P Promoter. Response of Selenoprotein P Expression to Cytokynes in Liver Cells. J Biol Chem 272: 29364-29371.
-
(1997)
J Biol Chem
, vol.272
, pp. 29364-29371
-
-
Dreher, I.1
Jakobs, T.C.2
Kohrle, J.3
-
22
-
-
0034856808
-
Modulation of selenoprotein P expression by TGF-beta 1 is mediated by Smad proteins
-
Mostert V, Dreher I, Köhrle J, Wolff S, Abel J (2001) Modulation of selenoprotein P expression by TGF-beta 1 is mediated by Smad proteins Biofactors 14: 135-142.
-
(2001)
Biofactors
, vol.14
, pp. 135-142
-
-
Mostert, V.1
Dreher, I.2
Köhrle, J.3
Wolff, S.4
Abel, J.5
-
23
-
-
33745938947
-
Identification of a common gene signature for type II cytokine-associated myeloid cells elicited in vivo in different pathologic conditions
-
Hassanzadeh Ghassabeh G, De Baetselier P, Brys L, Noel W, Van Ginderachter JA, et al. (2006) Identification of a common gene signature for type II cytokine-associated myeloid cells elicited in vivo in different pathologic conditions. Blood 108: 575-583.
-
(2006)
Blood
, vol.108
, pp. 575-583
-
-
Hassanzadeh Ghassabeh, G.1
De Baetselier, P.2
Brys, L.3
Noel, W.4
Van Ginderachter, J.A.5
-
24
-
-
1642633752
-
Inflamed about obesity
-
Lehrke M, Lazar MA (2004) Inflamed about obesity. Nat Med 10: 126-127.
-
(2004)
Nat Med
, vol.10
, pp. 126-127
-
-
Lehrke, M.1
Lazar, M.A.2
-
25
-
-
0033880884
-
Activated protein C inhibits lipopolysaccharide-induced nuclear translocation of nuclear factor kappaB (NF-kappaB) and tumour necrosis factor alpha (TNFalpha) production in the THP-1 monocytic cell line
-
White B, Schmidt M, Murphy C, Livingstone W, O'Toole D, et al. (2000) Activated protein C inhibits lipopolysaccharide-induced nuclear translocation of nuclear factor kappaB (NF-kappaB) and tumour necrosis factor alpha (TNFalpha) production in the THP-1 monocytic cell line. Br J Haematol 110: 130-134.
-
(2000)
Br J Haematol
, vol.110
, pp. 130-134
-
-
White, B.1
Schmidt, M.2
Murphy, C.3
Livingstone, W.4
O'Toole, D.5
-
26
-
-
0036339949
-
Activated protein C inhibits lipopolysaccharide-induced tumor necrosis factor-alpha production by inhibiting activation of both nuclear factor-kappa B and activator protein-1 in human monocytes
-
Yuksel M, Okajima K, Uchiba M, Horiuchi S, Okabe H (2002) Activated protein C inhibits lipopolysaccharide-induced tumor necrosis factor-alpha production by inhibiting activation of both nuclear factor-kappa B and activator protein-1 in human monocytes. Thrombosis and haemostasis 88: 267-273.
-
(2002)
Thrombosis and haemostasis
, vol.88
, pp. 267-273
-
-
Yuksel, M.1
Okajima, K.2
Uchiba, M.3
Horiuchi, S.4
Okabe, H.5
-
28
-
-
29644441714
-
NF-{kappa}B and Activator Protein 1 Response Elements and the Role of Histone Modifications in IL-1{beta}-Induced TGF-{beta}1 Gene Transcription
-
Lee K-Y, Ito K, Hayashi R, Jazrawi EPI, Barnes PJ, et al. (2006) NF-{kappa}B and Activator Protein 1 Response Elements and the Role of Histone Modifications in IL-1{beta}-Induced TGF-{beta}1 Gene Transcription. J Immunol 176: 603-615.
-
(2006)
J Immunol
, vol.176
, pp. 603-615
-
-
Lee, K.-Y.1
Ito, K.2
Hayashi, R.3
Jazrawi, E.P.I.4
Barnes, P.J.5
-
29
-
-
0033821409
-
Glucocorticoid Receptor Recruitment of Histone Deacetylase 2 Inhibits Interleukin-1beta -Induced Histone H4 Acetylation on Lysines 8 and 12
-
Ito K, Barnes PJ, Adcock IM (2000) Glucocorticoid Receptor Recruitment of Histone Deacetylase 2 Inhibits Interleukin-1beta -Induced Histone H4 Acetylation on Lysines 8 and 12. Mol Cell Biol 20: 6891-6903.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 6891-6903
-
-
Ito, K.1
Barnes, P.J.2
Adcock, I.M.3
-
30
-
-
33846411054
-
Inhibition of Tumor Necrosis Factor-{alpha}-Inducible Inflammatory Genes by Interferon-{gamma} Is Associated with Altered Nuclear Factor-{kappa}B Transactivation and Enhanced Histone Deacetylase Activity
-
Keslacy S, Tliba O, Baidouri H, Amrani Y (2007) Inhibition of Tumor Necrosis Factor-{alpha}-Inducible Inflammatory Genes by Interferon-{gamma} Is Associated with Altered Nuclear Factor-{kappa}B Transactivation and Enhanced Histone Deacetylase Activity. Mol Pharmacol 71: 609-618.
-
(2007)
Mol Pharmacol
, vol.71
, pp. 609-618
-
-
Keslacy, S.1
Tliba, O.2
Baidouri, H.3
Amrani, Y.4
-
31
-
-
49049090212
-
Histone Acetylation and Flagellin Are Essential for Legionella pneumophila-Induced Cytokine Expression
-
Schmeck B, Lorenz J, N'Guessan PD, Opitz B, van Laak V, et al. (2008) Histone Acetylation and Flagellin Are Essential for Legionella pneumophila-Induced Cytokine Expression. J Immunol 181: 940-947.
-
(2008)
J Immunol
, vol.181
, pp. 940-947
-
-
Schmeck, B.1
Lorenz, J.2
N'Guessan, P.D.3
Opitz, B.4
van Laak, V.5
-
32
-
-
46749144173
-
Histone deacetylase inhibition modulates indoleamine 2,3-dioxygenase-dependent DC functions and regulates experimental graft-versus-host disease in mice
-
Reddy P, Sun Y, Toubai T, Duran-Struuck R, Clouthier SG, et al. (2008) Histone deacetylase inhibition modulates indoleamine 2,3-dioxygenase-dependent DC functions and regulates experimental graft-versus-host disease in mice. J Clin Invest 118: 2562-2573.
-
(2008)
J Clin Invest
, vol.118
, pp. 2562-2573
-
-
Reddy, P.1
Sun, Y.2
Toubai, T.3
Duran-Struuck, R.4
Clouthier, S.G.5
-
33
-
-
0037022598
-
The antitumor histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits antiinflammatory properties via suppression of cytokines
-
Leoni F, Zaliani A, Bertolini G, Porro G, Pagani P, et al. (2002) The antitumor histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits antiinflammatory properties via suppression of cytokines. PNAS 99: 2995-3000.
-
(2002)
PNAS
, vol.99
, pp. 2995-3000
-
-
Leoni, F.1
Zaliani, A.2
Bertolini, G.3
Porro, G.4
Pagani, P.5
-
34
-
-
42549129871
-
Simvastatin Reduces Chlamydophila pneumoniae-Mediated Histone Modifications and Gene Expression in Cultured Human Endothelial Cells
-
Schmeck B, Beermann W, N'Guessan PD, Hocke AC, Opitz B, et al. (2008) Simvastatin Reduces Chlamydophila pneumoniae-Mediated Histone Modifications and Gene Expression in Cultured Human Endothelial Cells. Circ Res 102: 888-895.
-
(2008)
Circ Res
, vol.102
, pp. 888-895
-
-
Schmeck, B.1
Beermann, W.2
N'Guessan, P.D.3
Hocke, A.C.4
Opitz, B.5
-
35
-
-
35948983828
-
Histone deacetylase inhibitors decrease Toll-like receptor-mediated activation of proinflammatory gene expression by impairing transcription factor recruitment
-
Bode KA, Schroder K, Hume DA, Ravasi T, Heeg K, et al. (2007) Histone deacetylase inhibitors decrease Toll-like receptor-mediated activation of proinflammatory gene expression by impairing transcription factor recruitment. Immunology 122: 596-606.
-
(2007)
Immunology
, vol.122
, pp. 596-606
-
-
Bode, K.A.1
Schroder, K.2
Hume, D.A.3
Ravasi, T.4
Heeg, K.5
-
36
-
-
0041312644
-
Early mitotic degradation of the homeoprotein HOXC10 is potentially linked to cell cycle progression
-
Gabellini D, Colaluca IN, Vodermaier HC, Biamonti G, Giacca M, et al. (2003) Early mitotic degradation of the homeoprotein HOXC10 is potentially linked to cell cycle progression. EMBO 22: 3715-3724.
-
(2003)
EMBO
, vol.22
, pp. 3715-3724
-
-
Gabellini, D.1
Colaluca, I.N.2
Vodermaier, H.C.3
Biamonti, G.4
Giacca, M.5
-
38
-
-
0036782277
-
Deregulated homeobox gene expression in cancer: Cause or consequence?
-
Abate-Shen C (2002) Deregulated homeobox gene expression in cancer: cause or consequence? Nat Rev Cancer 2: 777-785.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 777-785
-
-
Abate-Shen, C.1
-
39
-
-
0033662322
-
SOCS Proteins, Regulators of Intracellular Signaling
-
Chen XP, Losman JA, Rothman P (2000) SOCS Proteins, Regulators of Intracellular Signaling. Immunity 13: 287-290.
-
(2000)
Immunity
, vol.13
, pp. 287-290
-
-
Chen, X.P.1
Losman, J.A.2
Rothman, P.3
-
40
-
-
3042823699
-
The suppressor of cytokine signaling (SOCS)-7 interacts with the actin cytoskeleton through vinexin
-
Martens N, Wery M, Wang P, Braet F, Gertler A, et al. (2004) The suppressor of cytokine signaling (SOCS)-7 interacts with the actin cytoskeleton through vinexin. Experimental Cell Research 298: 239-248.
-
(2004)
Experimental Cell Research
, vol.298
, pp. 239-248
-
-
Martens, N.1
Wery, M.2
Wang, P.3
Braet, F.4
Gertler, A.5
-
41
-
-
0033544921
-
Vinexin Forms a Signaling Complex with Sos and Modulates Epidermal Growth Factorinduced c-Jun N-terminal Kinase/Stress-activated Protein Kinase Activities
-
Akamatsu M, Aota S-i, Suwa A, Ueda K, Amachi T, et al. (1999) Vinexin Forms a Signaling Complex with Sos and Modulates Epidermal Growth Factorinduced c-Jun N-terminal Kinase/Stress-activated Protein Kinase Activities. J Biol Chem 274: 35933-35937.
-
(1999)
J Biol Chem
, vol.274
, pp. 35933-35937
-
-
Akamatsu, M.1
Aota, S.-I.2
Suwa, A.3
Ueda, K.4
Amachi, T.5
|