Combinatorial mutation interference analysis reveals functional nucleotides required for DNA catalysis

Angewandte Chemie - International Edition

Volumn 49, Issue 45, 2010, Pages 8504-8508

  Wachowius, Falk ^a   Javadi Zarnaghi, Fatemeh ^a   Höbartner, Claudia ^a  

^a MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

Author keywords

Catalytic DNA; Deoxyribozymes; Mutation analysis; RNA ligation; Solid phase synthesis

Indexed keywords

ACTIVE SITE; CATALYTIC DNA; DEOXYRIBOZYMES; EFFICIENT METHOD; GUANOSINES; INTERFERENCE ANALYSIS; MUTATION ANALYSIS; SOLID-PHASE SYNTHESIS;

CATALYSIS; NUCLEOTIDES; RNA; SOFTWARE TESTING;

DNA;

DEOXYRIBOZYME; NUCLEOTIDE; ORGANOPHOSPHORUS COMPOUND; PHOSPHORAMIDOUS ACID; RNA;

ARTICLE; CHEMISTRY; CONFORMATION; GENETICS; METABOLISM; MUTATION; NUCLEOTIDE SEQUENCE;

BASE SEQUENCE; DNA, CATALYTIC; MUTATION; NUCLEIC ACID CONFORMATION; NUCLEOTIDES; ORGANOPHOSPHORUS COMPOUNDS; RNA;

EID: 78149426143     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201003940     Document Type: Article

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