BDNF-dependent enhancement of exocytosis in cultured cortical neurons requires translation but not transcription

Brain Research

Volumn 815, Issue 1, 1999, Pages 140-149

  Bradley, John ^a   Sporns, Olaf ^a  

^a NEUROSCIENCES INSTITUTE   (United States)

Author keywords

Brain derived neurotrophic factor; Exocytosis; FM1 43; Neurotransmitter; Synaptic plasticity; Synaptic vesicle

Indexed keywords

5,6 DICHLOROBENZIMIDAZOLE RIBOSIDE; ANISOMYCIN; BRAIN DERIVED NEUROTROPHIC FACTOR; CYCLOHEXIMIDE; DACTINOMYCIN; DYE; K 252A; POTASSIUM CHLORIDE; RNA;

ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEPOLARIZATION; DOSE TIME EFFECT RELATION; EMBRYO; EXOCYTOSIS; INCUBATION TIME; MOLECULAR DYNAMICS; NERVE CELL CULTURE; NERVE CELL PLASTICITY; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; RAT; RNA TRANSCRIPTION; RNA TRANSLATION; SYNAPSE VESICLE;

ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELLS, CULTURED; ELECTROPHYSIOLOGY; EXOCYTOSIS; FLUORESCENT DYES; GENE EXPRESSION; MEMBRANE POTENTIALS; NERVE TISSUE PROTEINS; NEURONAL PLASTICITY; NEURONS; POTASSIUM; PROTEIN BIOSYNTHESIS; PYRIDINIUM COMPOUNDS; QUATERNARY AMMONIUM COMPOUNDS; RATS; RATS, INBRED WKY; SYNAPTIC TRANSMISSION; SYNAPTIC VESICLES; TIME FACTORS; TRANSCRIPTION, GENETIC;

EID: 0033513997     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(98)01112-3     Document Type: Article

References (41)

1. Lewin G.R., Barde Y.A. Physiology of the neurotrophins. Annu Rev Neurosci. 19:1996;289-317.
2. Kaplan D.R., Miller F.D. Signal transduction by the neurotrophin receptors. Curr Opin Cell Biol. 9:1997;213-221.
3. Berninger B., Poo M.M. Fast actions of neurotrophic factors. Curr Opin Neurobiol. 6:1996;324-330.
4. Bonhoeffer T. Neurotrophins and activity-dependent development of the neocortex. Curr Opin Neurobiol. 6:1996;119-126.
5. Kang H., Schuman E.M. Long-lasting neurotrophin-induced enhancement of synaptic transmission in the adult hippocampus. Science. 267:1995;1658-1662.
6. Patterson S.L., Abel T., Deuel T.A., Martin K.C., Rose J.C., Kandel E.R. Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice. Neuron. 16:1996;1137-1145.
7. Akaneya Y., Tsumoto T., Kinoshita S., Hatanaka H. Brain-derived neurotrophic factor enhances long-term potentiation in rat visual cortex. J Neurosci. 17:1997;6707-6716.
8. Carmignoto G., Pizzorusso T., Tia S., Vicini S. Brain-derived neurotrophic factor and nerve growth factor potentiate excitatory synaptic transmission in the rat visual cortex. J Physiol (Lond). 498:1997;153-164.
9. Messaoudi E., Bardsen K., Srebro B., Bramham C.R. Acute intrahippocampal infusion of BDNF induces lasting potentiation of synaptic transmission in the rat dentate gyrus. J Neurophysiol. 79:1998;496-499.
10. Lessmann V., Gottmann K., Heumann R. BDNF and NT-4/5 enhance glutamatergic synaptic transmission in cultured hippocampal neurones. Neuroreport. 6:1994;21-25.
11. Levine E.S., Dreyfus C.F., Black I.B., Plummer M.R. Brain-derived neurotrophic factor rapidly enhances synaptic transmission in hippocampal neurons via postsynaptic tyrosine kinase receptors. Proc Natl Acad Sci USA. A 92:1995;8074-8077.
12. Figurov A., Pozzo-Miller L.D., Olafsson P., Wang T., Lu B. Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus. Nature. 381:1996;706-709.
13. Goodman L.J., Valverde J., Lim F., Geschwind M.D., Federoff H.J., Geller A.I., Hefti F. Regulated release and polarized localization of brain-derived neurotrophic factor in hippocampal neurons. Mol Cell Neurosci. 7:1996;222-238.
14. Tongiorgi E., Righi M., Cattaneo A. Activity-dependent dendritic targeting of BDNF and TrkB mRNAs in hippocampal neurons. J Neurosci. 17:1997;9492-9505.
15. Haubensak W., Narz F., Heumann R., Lessmann V. BDNF-GFP containing secretory granules are localized in the vicinity of synaptic junctions of cultured cortical neurons. J Cell Sci. 111:1998;1483-1493.
16. Schuman E.M. Molecular consequences of diffusible signaling: locally distributed synaptic enhancement in hippocampal neurons. Semin Cell Biol. 5:1994;251-261.
17. Wang X., Berninger B., Poo M.M. Localized synaptic actions of neurotrophin-4. J Neurosci. 18:1998;4985-4992.
18. Lohof A.M., Ip N.Y., Poo M.M. Potentiation of developing neuromuscular synapses by the neurotrophins NT-3 and BDNF. Nature. 363:1993;350-353.
19. Stoop R., Poo M.M. Synaptic modulation by neurotrophic factors: differential and synergistic effects of brain-derived neurotrophic factor and ciliary neurotrophic factor. J Neurosci. 16:1996;3256-3264.
20. Lessmann V., Heumann R. Modulation of unitary glutamatergic synapses by neurotrophin-4/5 or brain-derived neurotrophic factor in hippocampal microcultures: presynaptic enhancement depends on pre-established paired-pulse facilitation. Neursoscience. 86:1998;399-413.
21. Gottschalk W., Pozzo-Miller L.D., Figurov A., Lu B. Presynaptic modulation of synaptic transmission and plasticity by brain-derived neurotrophic factor in the developing hippocampus. J Neurosci. 18:1998;6830-6839.
22. Li Y.X., Xu Y., Ju D., Lester H.A., Davidson N., Schuman E.M. Expression of a dominant negative TrkB receptor, T1, reveals a requirement for presynaptic signaling in BDNF-induced synaptic potentiation in cultured hippocampal neurons. Proc Natl Acad Sci USA. A 95:1998;10884-10889.
23. Wang X.H., Poo M.M. Potentiation of developing synapses by postsynaptic release of neurotrophin-4. Neuron. 19:1997;825-835.
24. Betz W.J., Mao F., Bewick G.S. Activity-dependent fluorescent staining and destaining of living vertebrate motor nerve terminals. J Neurosci. 12:1992;363-375.
25. Malgaroli A., Ting A.E., Wendland B., Bergamaschi A., Villa A., Tsien R.W., Scheller R.H. Presynaptic component of long-term potentiation visualized at individual hippocampal synapses. Science. 268:1995;1624-1628.
26. Ryan T.A., Ziv N.E., Smith S.J. Potentiation of evoked vesicle turnover at individually resolved synaptic boutons. Neuron. 17:1996;125-134.
27. Sporns O., Jenkinson S. Potassium ion- and nitric oxide-induced exocytosis from populations of hippocampal synapses during synaptic maturation in vitro. Neuroscience. 80:1997;1057-1073.
28. Ryan T.A., Smith S.J. Vesicle pool mobilization during action potential firing at hippocampal synapses. Neuron. 14:1995;983-989.
29. Seabold G.K., Luo J., Miller M.W. Effect of ethanol on neurotrophin-mediated cell survival and receptor expression in cultures of cortical neurons. Brain Res Dev Brain Res. 108:1998;139-145.
30. Iwasaki Y., Gay B., Wada K., Koizumi S. Association of the Src family tyrosine kinase Fyn with TrkB. J Neurochem. 71:1998;106-111.
31. Knusel B., Hefti F. K-252 compounds: modulators of neurotrophin signal transduction. J Neurochem. 59:1992;1987-1996.
32. Takei N., Sasaoka K., Inoue K., Takahashi M., Endo Y., Hatanaka H. Brain-derived neurotrophic factor increases the stimulation-evoked release of glutamate and the levels of exocytosis-associated proteins in cultured cortical neurons from embryonic rats. J Neurochem. 68:1997;370-375.
33. Kang H., Schuman E.M. A requirement for local protein synthesis in neurotrophin-induced hippocampal synaptic plasticity. Science. 273:1996;1402-1406.
34. Henkel A.W., Lubke J., Betz W.J. FM1-43 dye ultrastructural localization in and release from frog motor nerve terminals. Proc Natl Acad Sci USA. A 93:1996;1918-1923.
35. Murthy V.N., Sejnowski T.J., Stevens C.F. Heterogeneous release properties of visualized individual hippocampal synapses. Neuron. 18:1997;599-612.
36. Knipper M., da Penha Berzaghi M., Blochl A., Breer H., Thoenen H., Lindholm D. Positive feedback between acetylcholine and the neurotrophins nerve growth factor and brain-derived neurotrophic factor in the rat hippocampus. Eur J Neurosci. 6:1994;668-671.
37. Blochl A., Sirrenberg C. Neurotrophins stimulate the release of dopamine from rat mesencephalic neurons via Trk and p75Lntr receptors. J Biol Chem. 271:1996;21100-21107.
38. Jovanovic J.N., Benfenati F., Siow Y.L., Sihra T.S., Sanghera J.S., Pelech S.L., Greengard P., Czernik A.J. Neurotrophins stimulate phosphorylation of synapsin I by MAP kinase and regulate synapsin I-actin interactions. Proc Natl Acad Sci USA. A 93:1996;3679-3683.
39. Torre E.R., Steward O. Demonstration of local protein synthesis within dendrites using a new cell culture system that permits the isolation of living axons and dendrites from their cell bodies. J Neurosci. 12:1992;762-772.
40. Steward O. Dendrites as compartments for macromolecular synthesis. Proc Natl Acad Sci USA. A 91:1994;10766-10768.
41. Knowles R.B., Kosik K.S. Neurotrophin-3 signals redistribute RNA in neurons. Proc Natl Acad Sci USA. A 94:1997;14804-14808.