Association between exposure-relevant polymorphisms in CYP1B1, EPHX1, NQO1, GSTM1, GSTP1 and GSTT1 and risk of colorectal cancer in a Czech population

Oncology Reports

Volumn 24, Issue 5, 2010, Pages 1347-1353

  Hlavata, Ivona ^a,b   Vrana, David ^a,c,d   Smerhovsky, Zdenek ^a,b   Pardini, Barbara ^e   Naccarati, Alessio ^e   Vodicka, Pavel ^e   Novotny, Jan ^b,c   Mohelnikova Duchonova, Beatrice ^a,c   Soucek, Pavel ^a  

^a NATIONAL INSTITUTE OF PUBLIC HEALTH   (Czech Republic)

^b CHARLES UNIVERSITY   (Czech Republic)

^c CHARLES UNIVERSITY   (Czech Republic)

^d Atlas Hospital   (Czech Republic)

^e INSTITUTE OF EXPERIMENTAL MEDICINE   (Czech Republic)

Author keywords

Colorectal cancer; Cytochrome P450; Glutathione stransferase; Polymorphism; Risk

Indexed keywords

CELLOBIOSE QUINONE OXIDOREDUCTASE; CYTOCHROME P450 1B1; EPOXIDE HYDROLASE; GLUTATHIONE TRANSFERASE M1; GLUTATHIONE TRANSFERASE P1; GLUTATHIONE TRANSFERASE T1; SERINE;

ADULT; AGED; ALLELE; ARTICLE; CANCER RISK; CARCINOGENESIS; CODON; COLONOSCOPY; COLORECTAL CANCER; CONTROLLED STUDY; CZECH REPUBLIC; DNA POLYMORPHISM; ENZYME ACTIVITY; FEMALE; GENE INTERACTION; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOTE; HOSPITAL BASED CASE CONTROL STUDY; HUMAN; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SINGLE NUCLEOTIDE POLYMORPHISM; WILD TYPE;

ADULT; AGED; AGED, 80 AND OVER; CASE-CONTROL STUDIES; COLORECTAL NEOPLASMS; CYTOCHROME P-450 ENZYME SYSTEM; CZECH REPUBLIC; EPOXIDE HYDROLASES; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; GLUTATHIONE S-TRANSFERASE PI; GLUTATHIONE TRANSFERASE; HUMANS; MIDDLE AGED; NAD(P)H DEHYDROGENASE (QUINONE); POLYMORPHISM, SINGLE NUCLEOTIDE; YOUNG ADULT;

EID: 78149301724     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or-00000992     Document Type: Article

References (47)

1. Kamangar F, Dores GM and Anderson WF: Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world. J Clin Oncol 24: 2137-2150, 2006.
2. Ferlay J, Autier P, Boniol M, Heanue M, Colombet M and Boyle P: Estimates of the cancer incidence and mortality in Europe in 2006. Ann Oncol 18: 581-592, 2007.
3. Cancer Incidence 2005 in the Czech Republic. IHIS CR, NOR CR, Czech Republic, pp30-33, 2008.
4. Rustgi AK: The genetics of hereditary colon cancer. Genes Dev 21: 2525-2538, 2007.
5. Norat T, Bingham S, Ferrari P, et al: Meat, fish, and colorectal cancer risk: the European Prospective Investigation into cancer and nutrition. J Natl Cancer Indy 97: 906-916, 2005. (Pubitemid 41417942)
6. Liang PS, Chen TY and Giovannucci E: Cigarette smoking and colorectal cancer incidence and mortality: systematic review and meta-analysis. Int J Cancer 124: 2406-2415, 2009.
7. Soucek P: Xenobiotics. In: Encyclopedia of Cancer. Schwab M (ed). 2nd edition. Springer-Verlag, New York, 2008.
8. Boursi B and Arber N: Current and future clinical strategies in colon cancer prevention and the emerging role of chemoprevention. Curr Pharm Des 13: 2274-2282, 2007.
9. Küry S, Buecher B, Robiou-du-Pont S, et al: Combinations of cytochrome P450 polymorphisms enhancing the risk for sporadic colorectal cancer related to red meat consumption. Cancer Epidemiol Biomarkers Prev 16: 1460-1467, 2007.
10. Hassett C, Aicher L, Sidhu JS and Omiecinski CJ: Human microsomal epoxide hydrolase: genetic polymorphism and functional expression in vitro of amino acid variants. Hum Mol Genet 3: 421-428, 1994.
11. Robien K, Boynton A and Ulrich CM: Pharmacogenetics of folate-related drug targets in cancer treatment. Pharmacogenomics 6: 673-689, 2005.
12. Van der Logt EM, Bergevoet SM, Roelofs HM, et al: Role of epoxide hydrolase, NADP;H:quinone oxidoreductase, cytochrome P450 2E1 or alcohol dehydrogenase genotypes in susceptibility to colorectal cancer. Mutat Res 593: 39-49, 2006.
13. Traver RD, Siegel D, Beall HD, Phillips RM, Gibson NW, Franklin WA and Ross D: Characterization of a polymorphism in NADP(H):quinone oxidoreductase DT-diaphorase. Br J Cancer 75: 69-75, 1997.
14. Begleiter A, Hewitt D, Maksymiuk AW, Ross DA and Bird RP: A NADP;H:quinone oxidoreductase 1 polymorphism is a risk factor for human colon cancer. Cancer Epidemiol Biomarkers Prev 15: 2422-2426, 2006.
15. Mitrou PN, Watson MA, Loktionov AS, et al: Role of NQO1C609T and EPHX1 gene polymorphisms in the association of smoking and alcohol with sporadic distal colorectal adenomas: results from the UKFSS Study. Carcinogenesis 28: 875-882, 2007.
16. Zimniak P, Nanduri B, Pikula S, et al: Naturally occuring human glutathione S-transferase GSTP1-1 isoforms with isoleucine and valine in position 104 differ in enzymic properties. Eur J Biochem 224: 893-899, 1994.
17. Ferraz JM, Zinzindohoué F, Lecomte T, et al: Impact of GSTT1, GSTM1, GSTP1 and NAT2 genotypes on KRAS2 and TP53 gene mutations in colorectal cancer. Int J Cancer 110: 183-187, 2004.
18. Moore LE, Huang WY, Chatterjee N, et al: GSTM1, GSTT1, and GSTP1 polymorphisms and risk of advanced colorectal adenoma. Cancer Epidemiol Biomarkers Prev 14: 1823-1827, 2005.
19. Naccarati A, Soucek P, Stetina R, et al: Genetic polymorphisms and possible gene-gene interactions in metabolic and DNA repair genes: effects on DNA damage. Mutat Res 593: 22-31, 2006.
20. Vasen HF, Watson P, Mecklin JP and Lynch HT: New clinical criteria for hereditary non-polyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the International Collaborative group on HNPCC. Gastroenterology 116: 1453-1456, 1999.
21. Landi S, Gemignani F, Naccarati A, et al: Polymorphisms within micro-RNA-binding sites and risk of sporadic colorectal cancer. Carcinogenesis 29: 579-584, 2008.
22. Sarmanova J, Susova S, Gut I, et al: Breast cancer: role of polymorphisms in biotransformation enzymes. Eur J Hum Genet 12: 848-854, 2004.
23. Vrana D, Pikhart H, Mohelnikova-Duchonova B, et al: The association between Glutathione S-transferase Gene polymorphisms and pancreatic cancer in central European Slavonic population. Mutat Res 680: 78-81, 2009.
24. Dofkova M, Kopriva V, Resova D, Rehurkova I and Ruprich J: The development of food consumption in the Czech Republic after 1989. Public Health Nutr 4: 999-1003, 2001.
25. Heath SC, Gut IG, Brennan P, et al: Investigation of the fine structure of European populations with applications to disease association studies. Eur J Hum Genet 16: 1413-1429, 2008.
26. Mohelnikova-Duchonova B, Vrana D, Holcatova I, Ryska M, Smerhovsky Z and Soucek P: CYP2A13, ADH1B and ADH1C gene polymorphisms and pancreatic cancer risk. Pancreas 39: 144-148, 2010.
27. McFadden E, Luben R, Wareham N, Bingham S and Khaw KT: Occupational social class, educational level, smoking and body mass index, and cause-specific mortality in men and women: a prospective study in the European Prospective Investigation of Cancer and Nutrition in Norfolk (EPIC-Norfolk) cohort. Eur J Epidemiol 23: 511-522, 2008.
28. Sengupta N, Gill KA, MacFie TS, Lai CS, Suraweera N, Mcdonald S and Silver A: Management of colorectal cancer: a role for genetics in prevention and treatment? Pathol Res Pract 204: 469-477, 2008.
29. Harriss DJ, Atkinson G, George K, et al: Lifestyle factors and colorectal cancer risk (1): systematic review and meta-analysis of associations with body mass index. Colorectal Dis 11: 547-563, 2009.
30. Zejglicová K, Kratenová J, Maly M and Kubí nová R: Incidence of risk factors of chronic non-infectious diseases including socio-economic factors in the urban middle age population in the Czech Republic-results of HELEN study. Cas Lek Cesk 145: 936-942, 2006.
31. Singh H, Turner D, Xue L, Targownik LE and Bernstein CN: Risk of developing colorectal cancer following a negative colonoscopy examination: evidence for a 10-year interval between colonoscopies. JAMA 295: 2366-2373, 2006.
32. Sachse C, Smith G, Wilkie MJ, et al: A pharmacogenetic study to investigate the role of dietary carcinogens in the etiology of colorectal cancer. Carcinogenesis 23: 1839-1849, 2002.
33. Chao C, Zhang ZF, Berthiller J, Boffetta P and Hashibe M: NAD(P)H:quinone oxidoreductase 1 NQO1 Pro187Ser polymorphism and the risk of lung, bladder, and colorectal cancers: a meta-analysis. Cancer Epidemiol Biomarkers Prev 15: 979-987, 2006.
34. Ates NA, Tamer L, Ates C, Ercan B, Elipek T, Ocal K and Camdeviren H: Glutathione S-transferase M1, T1, P1 genotypes and risk for development of colorectal cancer. Biochem Genet 43: 149-163, 2005. (Pubitemid 40543712)
35. Yoshioka M, Katoh T, Nakano M, Takasawa S, Nagata N and Itoh H: Glutathione S-transferase (GST) M1, T1, P1, N-acetyltransferase (NAT) 1 and 2 genetic polymorphisms and susceptibility to colorectal cancer. J UOEH 21: 133-147, 1999.
36. Ye Z and Parry JM: Genetic polymorphisms in the cytochrome P450 1A1, glutathione S-transferase M1 and T1, and susceptibility to colon cancer. Teratog Carcinog Mutagen 22: 385-392, 2002.
37. Little J, Sharp L, Masson LF, Brockton NT, Cotton SC, Haites NE and Cassidy J: Colorectal cancer and genetic polymorphisms of CYP1A1, GSTM1 and GSTT1: a case-control study in the Grampian region of Scotland. Int J Cancer 119: 2155-2164, 2006.
38. Hoensch H, Peters WH, Roelofs HM and Kirch W: Expression of the glutathione enzyme system of human colon mucosa by localisation, gender and age. Curr Med Res Opin 22: 1075-1083, 2006.
39. Stoehlmacher J, Park DJ, Zhang W, Groshen S, Tsao-Wei DD, Yu MC and Lenz HJ: Association between glutathione Stransferase P1, T1, and M1 genetic polymorphism and survival of patients with metastatic colorectal cancer. J Natl Cancer Inst 94: 936-942, 2002.
40. Huang K, Sandler RS, Millikan RC, Schroeder JC, North KE and Hu J: GSTM1 and GSTT1 polymorphisms, cigarette smoking, and risk of colon cancer: a population-based casecontrol study in North Carolina (United States). Cancer Causes Control 17: 385-394, 2006.
41. Skjelbred CF, Saebø M, Hjartåker A, et al: Meat, vegetables and genetic polymorphisms and the risk of colorectal carcinomas and adenomas. BMC Cancer 7: 228, 2007.
42. Gao Y, Cao Y, Tan A, Liao C, Mo Z and Gao F: Glutathione Stransferase M1 polymorphism and sporadic colorectal cancer risk: an updating meta-analysis and HuGE review of 36 casecontrol studies. Ann Epidemiol 20: 108-121, 2010.
43. Bethke L, Webb E, Sellick G, et al: Polymorphisms in the cytochrome P450 genes CYP1A2, CYP1B1, CYP3A4, CYP3A5, CYP11A1, CYP17A1, CYP19A1 and colorectal cancer risk. BMC Cancer 7: 123, 2007.
44. Fan C, Jin M, Chen K, Zhang Y, Zhang S and Liu B: Case-only study of interactions between metabolic enzymes and smoking in colorectal cancer. BMC Cancer 7: 115, 2007.
45. Landi S, Gemignani F, Moreno V, et al: A comprehensive analysis of phase I and phase II metabolism gene polymorphisms and risk of colorectal cancer. Pharmacogenet Genomics 15: 535-546, 2005.
46. Bandiera S, Weidlich S, Harth V, Broede P, Ko Y and Friedberg T: Proteasomal degradation of human CYP1B1: effect of the Asn453Ser polymorphism on the post-translational regulation of CYP1B1 expression. Mol Pharmacol 67: 435-443, 2005.
47. McGrath M, Hankinson SE, Arbeitman L, Colditz GA, Hunter DJ and De Vivo I: Cytochrome P450 1B1 and catechol-O-methyltransferase polymorphisms and endometrial cancer susceptibility. Carcinogenesis 25: 559-565, 2004.