Multivalent ions control the transport through lysenin channels

Biophysical Chemistry

Volumn 152, Issue 1-3, 2010, Pages 40-45

  Fologea, Daniel ^a   Krueger, Eric ^a   Al Faori, Redwan ^a   Lee, Rachel ^a   Mazur, Yuriy I ^a   Henry, Ralph ^a   Arnold, Mark ^a   Salamo, Greg J ^a  

^a UNIVERSITY OF ARKANSAS   (United States)

Author keywords

Ligand gated channels; Lysenin; Multivalent ions; Pore forming toxins

Indexed keywords

ION; LYSENIN; PORE FORMING CYTOTOXIC PROTEIN; PROTEIN DERIVATIVE; UNCLASSIFIED DRUG;

ABSORPTION; ARTICLE; BILAYER MEMBRANE; CONCENTRATION RESPONSE; ION TRANSPORT; LIPID BILAYER; PRIORITY JOURNAL; THEORETICAL MODEL;

ABSORPTION; ION TRANSPORT; IONS; LIPID BILAYERS; METALS; TOXINS, BIOLOGICAL;

EID: 78149280232     PISSN: 03014622     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bpc.2010.07.004     Document Type: Article

References (40)

1. Ren Q., Paulsen I.T. Comparative analyses of fundamental differences in membrane transport capabilities in prokaryotes and eukaryotes. PLoS Comput. Biol. 2005, 1:190-201.
2. Saier M.H.J. Transmembrane transporters. Families of Transporters and Their Classification 2002, 1-17. Wiley-Liss, Inc, New Jersey. M.W. Quick (Ed.).
3. Delcour A.H. Structure and function of pore-forming β-barrels from bacteria. J. Mol. Microbiol. Biotechnol. 2002, 4:1-10.
4. Robertson K.M., Tieleman D.P. Molecular basis of voltage gating of OmpF porin. Biochem. Cell Biol. 2002, 80:517-523.
5. Wooley G.A., Lougheed T. Modeling ion channel regulation. Curr. Opin. Chem. Biol. 2003, 7:710-714.
6. Bezanilla F. How membrane proteins sense voltage. Nat. Rev. Mol. Cell Biol. 2008, 9:323-332.
7. Jordan P.C. Fifty years of progress in ion channel research. IEEE Trans. Nanobiosci. 2005, 4:3-9.
8. Bosmans F., Martin-Eauclaire M.-F., Swartz K.J. Deconstructing voltage sensor function and pharmacology in sodium channels. Nature 2008, 456:202-208.
9. Bezanilla F. Voltage-gated ion channels. IEEE Trans. Nanobiosci. 2005, 4:34-48.
10. Bashford C.L. Pore-forming toxins: attack and defence at the cell surface. Cell. Mol. Biol. Lett. 2001, 6:328-333.
11. Gonzalez M.R., Bischofberger M., Pernot L., van der Goot F.G., Freche B. Bacterial pore-forming toxins: the (w)hole story?. Cell. Mol. Life Sci. 2008, 65:493-507.
12. Parker M.W., Feil S.C. Pore-forming protein toxins: from structure to function. Prog. Biophys. Mol. Biol. 2005, 88:91-142.
13. Reig N., van der Goot F.G. About lipids and toxins. FEBS Lett. 2006, 580:5572-5579.
14. Bruhn H., Winkelmann J., Andersen C., Andra J., Leippe M. Dissection of the mechanisms of cytolytic and antibacterial activity of lysenin, a defence protein of the annelid Eisenia fetida. Dev. Comp. Immunol. 2006, 30:597-606.
15. Ishitsuka R., Kobayashi T. Lysenin: a new tool for investigating membrane lipid organization. Anat. Sci. Int. 2004, 79:184-190.
16. Kobayashi H., Ohta N., Umeda M. Biology of lysenin, a protein in the coelomic fluid of the earthworm Eisenia foetida. Int. Rev. Cytol. 2004, 236:45-99.
17. Shakor A.-B.A., Czurylo E.A., Sobota A. Lysenin, a unique sphingomyelin-binding protein. FEBS Lett. 2003, 542:1-6.
18. Yamaji-Hasegawa A., Makino A., Baba T., Senoh Y., Kimura-Suda H., Sato S.B., Terada N., Ohno S., Kiyokawa E., Umeda M., Kobayashi T. Oligomerization and pore formation of a sphingomyelin-specific toxin, lysenin. J. Biol. Chem. 2003, 278:22762-22770.
19. Ide T., Aoki T., Takeuchi Y., Yanagida T. Lysenin forms a voltage-dependent channel in artificial lipid bilayer membranes. Biochem. Biophys. Res. Commun. 2006, 346:288-292.
20. Kwiatkowska K., Hordejuk R., Szymczyk P., Kulma M., Abdel-Shakor A.-B., Plucienniczak A., Dolowy K., Szewczyk A., Sobota A. Lysenin-His, a sphingomyelin-recognizing toxin, requires tryptophan 20 for cation-selective channel assembly but not for membrane binding. Mol. Membr. Biol. 2007, 24:121-134.
21. Fologea D., Krueger E., Lee R., Naglak M., Mazur Y., Henry R., Salamo G. Controlled gating of lysenin pores. Biophys. Chem. 2010, 146:25-29.
22. Iyer R., Delcour A.H. Complex inhibition of OmpF and OmpC bacterial porins by polyamines. J. Biol. Chem. 1997, 272:18595-18601.
23. Iyer R., Wu Z., Woster P.M., Delcour A.H. Molecular basis for the polyamine-OmpF porin interactions: inhibitor and mutant studies. J. Mol. Biol. 2000, 297:933-945.
24. Menestrina G. Ionic channels formed by Staphylococcus aureus alpha-toxin: voltage-dependent inhibition by divalent and trivalent cations. J. Membr. Biol. 1986, 90:177-190.
25. Erdmann F., Jung M., Eyrisch S., Lang S., Helms V., Wagner R., Zimmerman R. Lanthanum ions inhibit the mammalian Sec61 complex in its channel dynamics and protein transport activity. FEBS Lett. 2009, 583:2359-2364.
26. Armstrong C.M., Cota G. Calcium block of Na+ channels and its effect on closing rate. Proc. Natl Acad. Sci. USA 1999, 96:4154-4157.
27. Armstrong C.M., Taylor S.R. Interaction of barium ions with potassium channels in squid giant axons. Biophys. J. 1980, 30:473-488.
28. Block B.M., Stacey W.C., Jones S.W. Surface charge and lanthanum block of calcium current in bullfrog sympathetic neurons. Biophys. J. 1998, 74:2278-2284.
29. Elinder F., Arhem P. Metal effects on ion channel gating. Q. Rev. Biophys. 2004, 36:373-427.
30. Lansman J.B. Blockade of current through single calcium channels by trivalent lanthanide cations. J. Gen. Physiol. 1990, 95:679-696.
31. Lansman J.B., Hess P., Tsien R.W. Blockade of current through single calcium channels by Cd2+, Mg2+, and Ca2+. J. Gen. Physiol. 1986, 88:321-347.
32. Zhang Y., Niu X., Brelidze T.I., Magleby K.L. Ring of negative charge in BK channels facilitates block by intracellular Mg2+ and polyamines through electrostatics. J. Gen. Physiol. 2006, 128:185-202.
33. Bayley H. Designated membrane channels and pores. Curr. Opin. Biotechnol. 1999, 10:94-103.
34. Bayley H., Braha O., Gu L.-Q. Stochastic sensing with protein pores. Adv. Mater. 2000, 12:139-142.
35. Braha O., Gu L.-Q., Zhou L., Lu X., Cheley S., Bayley H. Simultaneous stochastic sensing of divalent metal ions. Nat. Biotechnol. 2000, 18:1005-1007.
36. Braha O., Walker B., Cheley S., Kasianowicz J.J., Song L., Gouaux J.E., Bayley H. Designed protein pores as components for biosensors. Chemistry & Biochemistry 1997, 4:497-505.
37. Kasianowicz J.J., Burden D.L., Han L.C., Cheley S., Bayley H. Genetically engineered metal ion binding sites on the outside of a channel's transmembrane β-barrel. Biophys. J. 1999, 76:837-845.
38. Basle A., Iyer R., Delcour A.H. Subconductance states in OmpF gating. Biochim. Biophys. Acta 2004, 1664:100-107.
39. Benz R. Planar lipid bilayers (BLMs) and their applications. Investigation of Substrate-specific Porin Channels in Lipid Bilayer Membranes 2003, 347-369. Elsevier, Amsterdam. H.T. Tien, A. Ottova-Leitmannova (Eds.).
40. Zhu Y., Charles S. Probing synaptic vesicle fusion by altering mechanical properties of the neuronal surface membrane. Proc. Natl Acad. Sci. USA 2008, 105:18018-18022.