Controlled Gating of Lysenin Pores

Biophysical Chemistry

Volumn 146, Issue 1, 2010, Pages 25-29

  Fologea, Daniel ^a   Krueger, Eric ^b   Lee, Rachel ^b   Naglak, Matt ^b   Mazur, Yuriy ^b   Henry, Ralph ^a   Salamo, Greg ^b  

^a UNIVERSITY OF ARKANSAS   (United States)

^b UNIVERSITY OF ARKANSAS   (United States)

Author keywords

Lysenin; Negative conductance; Voltage gated pores

Indexed keywords

AMINO ACID; ION; LYSENIN; SPHINGOMYELIN; UNCLASSIFIED DRUG;

ARTICLE; ARTIFICIAL MEMBRANE; BILAYER MEMBRANE; CHANNEL GATING; CONCENTRATION (PARAMETERS); DYNAMICS; MEMBRANE POTENTIAL; MEMBRANE TRANSPORT; PH; POROSITY; PREDICTION; PRIORITY JOURNAL;

HYDROGEN-ION CONCENTRATION; ION CHANNEL GATING; LIPID BILAYERS; SPHINGOMYELINS; TOXINS, BIOLOGICAL;

EID: 70449704033     PISSN: 03014622     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bpc.2009.09.014     Document Type: Article

References (20)

1. Shakor A.-B.A., Czurylo E.A., and Sobota A. Lysenin, a unique sphingomyelin-binding protein. Federation of European Biochemical Societies Letters 542 (2003) 1-6
2. Kiyokawa E., Makino A., Ishii K., Otsuka N., Yamaji-Hasegawa A., and Kobayashi T. Recognition of Sphingomyelin by Lysenin and Lysenin-Related proteins. Biochemistry 43 (2004) 9766-9773
3. Kobayashi H., Ohta N., and Umeda M. Biology of Lysenin, a Protein in the Coelomic Fluid of the Earthworm Eisenia foetida. International Review of Cytology 236 (2004) 45-99
4. Bruhn H., Winkelmann J., Andersen C., Andra J., and Leippe M. Dissection of the mechanisms of cytolytic and antibacterial activity of lysenin, a defence protein of the annelid Eisenia fetida. Developmental and Comparative Immunology 30 (2006) 597-606
5. Yamaji-Hasegawa A., Makino A., Baba T., Senoh Y., Kimura-Suda H., Sato S.B., Terada N., Ohno S., Kiyokawa E., Umeda M., and Kobayashi T. Oligomerization and Pore Formation of a Sphingomyelin-specific toxin, Lysenin. The Journal of Biological Chemistry 278 (2003) 22762-22770
6. Czurylo E.A., Kulikova N., and Sobota A. Disturbance of smooth muscle regulatory function by Eisenia foetida toxin lysenin: Insight into the mechanism of smooth muscle contraction. Toxicon 51 (2008) 1090-1102
7. Ishitsuka R., and Kobayashi T. Lysenin: A new tool for investigating membrane lipid organization. Anatomical Science International 79 (2004) 184-190
8. Yamaji A., Sekizawa Y., Emoto K., Sakuraba H., and Inoue K. Lysenin, a novel sphingomyelin-specific binding protein. The Journal of Biological Chemistry 273 (1998) 5300-5306
9. Kwiatkowska K., Hordejuk R., Szymczyk P., Kulma M., Abdel-Shakor A.-B., Plucienniczak A., Dolowy K., Szewczyk A., and Sobota A. Lysenin-His, a sphingomyelin-recognizing toxin, requires tryptophan 20 for cation-selective channel assembly but not for membrane binding. Molecular Membrane Biology 24 (2007) 121-134
10. Ide T., Aoki T., Takeuchi Y., and Yanagida T. Lysenin forms a voltage-dependent channel in artificial lipid bilayer membranes. Biochemical and Biophysical Research Communications 346 (2006) 288-292
11. Ehrenstein G., Lecar H., and Nossal R. The Nature of the Negative Resistance in Bimolecular Lipid Membranes Containing Excitability-Inducing Material. The Journal of General Physiology 55 (1970) 119-133
12. Gudowska-Nowak E., Flyvbjerg H., Bennekou P., and Christopersen P. Hysteresis in Channel Gating. In: Bezrukov S.M. (Ed). Unsolved Problems of Noise and Fluctuations: UPoN 2002: Third International Conference, CP665 (2002), AIP, Washington DC 305-311
13. Bezanilla F. Voltage-Gated Ion Channels. IEEE Transactions on Nanobioscience 4 (2005) 34-48
14. Bezanilla F. The Voltage Sensor in Voltage-Dependent Ion Channels. Physiological Reviews 80 (2000) 555-592
15. Mueller P., and Rudin D.O. Resting and Action Potential in Experimental Bimolecular Lipid Membranes. Journal of Theoretical Biology 18 (1968) 222-258
16. Gallin E.K., and Livengood D.R. Inward rectification in mouse macrophages: evidence for a negative resistance region. American Journal of Physiology-Cell Physiology 241 (1981) C9-C17
17. +. Nature 291 (1981) 427-429
18. + channel correlate with occupancy of the pore. Biophysical Journal 61 (1992) 639-648
19. Miller C. A charged view of voltage-gated ion channels. Nature Structural Biology 10 (2003) 422-424
20. Swartz K.J. Sensing voltage across lipid membranes. Nature 456 (2008) 891-897