Probing synaptic vesicle fusion by altering mechanical properties of the neuronal surface membrane

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 46, 2008, Pages 18018-18022

  Zhu, Yongling ^a   Stevens, Charles F ^a  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

Exocytosis; FM dye; Fusion pore; pHluorin; Synapse

Indexed keywords

SURFACTANT;

ANIMAL CELL; ARTICLE; CALCIUM BINDING; CELL CYCLE; CELL FUSION; CELL SURFACE; CONTROLLED STUDY; NERVE CELL MEMBRANE; NONHUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RAT; SYNAPSE VESICLE;

ANIMALS; BIOMECHANICS; CALCIUM; CELL MEMBRANE; COLORING AGENTS; DETERGENTS; MEMBRANE FUSION; NEURONS; POROSITY; PRESYNAPTIC TERMINALS; RATS; SURFACE-ACTIVE AGENTS; SYNAPTIC VESICLES;

EID: 56649121982     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0809714105     Document Type: Article

References (22)

1. Stevens CF (2003) Neurotransmitter release at central synapses. Neuron 40: 381-388.
2. Sudhof TC (2004) The synaptic vesicle cycle. Annu Rev Neurosci 27:509-547.
3. Murthy VN, De Camilli P (2003) Cell biology of the presynaptic terminal. Annu Rev Neurosci 26:701-728.
4. Betz WJ, Bewick GS (1992) Optical analysis of synaptic vesicle recycling at the frog neuromuscular junction. Science 255:200-203.
5. Ryan TA, Smith SJ (1995) Vesicle pool mobilization during action potential firing at hippocampal synapses. Neuron 14:983-989.
6. Murthy VN, Sejnowski TJ, Stevens CF (1997) Heterogeneous release properties of visualized individual hippocampal synapses. Neuron 18:599-612.
7. Betz WJ, Mao F, Smith CB (1996) Imaging exocytosis and endocytosis. Curr Opin Neurobiol 6:365-371.
8. Ryan TA, Smith SJ, Reuter H (1996) The timing of synaptic vesicle endocytosis. Proc Natl Acad Sci USA 93:5567-5571.
9. Klingauf J, Kavalali ET, Tsien RW (1998) Kinetics and regulation of fast endocytosis at hippocampal synapses. Nature 394:581-585.
10. Nelson N (1992) Structure and function of V-ATPases in endocytic and secretory organelles. J Exp Biol 172:149-153.
11. Miesenbock G, De Angelis DA, Rothman JE (1998) Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteins. Nature 394:192-195.
12. Sankaranarayanan S, De Angelis D, Rothman JE, Ryan TA (2000) The use of pHluorins for optical measurements of presynaptic activity. Biophys J 79:2199-2208.
13. Henkel AW, Betz WJ (1995) Staurosporine blocks evoked release of FM1-43 but not acetylcholine from frog motor nerve terminals. J Neurosci 15:8246-8258.
14. Ziv NE, Smith SJ (1996) Evidence for a role of dendritic filopodia in synaptogenesis and spine formation. Neuron 17:91-102.
15. Spruce AE, Breckenridge LJ, Lee AK, Almers W (1990) Properties of the fusion pore that forms during exocytosis of a mast cell secretory vesicle. Neuron 4:643-654.
16. Klyachko VA, Jackson MB (2002) Capacitance steps and fusion pores of small and large-dense-core vesicles in nerve terminals. Nature 418:89-92.
17. He L, Wu XS, Mohan R, Wu LG (2006) Two modes of fusion pore opening revealed by cell-attached recordings at a synapse. Nature 444:102-105.
18. Stevens CF, Williams JH (2000) "Kiss and run" exocytosis at hippocampal synapses. Proc Natl Acad Sci USA 97:12828-12833.
19. Murthy VN, Schikorski T, Stevens CF, Zhu Y (2001) Inactivity produces increases in neurotransmitter release and synapse size. Neuron 32:673-682.
20. Xia Z, Dudek H, Miranti CK, Greenberg ME (1996) Calcium influx via the NMDA receptor induces immediate early gene transcription by a MAP kinase/ERK-dependent mechanism. J Neurosci 16:5425-5436.
21. Murthy VN, Stevens CF (1998) Synaptic vesicles retain their identity through the endocytic cycle. Nature 392:497-501.
22. Davies JT, Rideal EK (1961) in Interfacial Phenomena (Academic, New York), p 167.