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Volumn 76, Issue 10, 2010, Pages 787-794

The effect of homocysteine on the clinical outcomes of ventilated patients with severe sepsis

Author keywords

Homocysteine; Sepsis; Shock, septic

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); BLOOD CLOTTING FACTOR 5 LEIDEN; CREATININE; CYANOCOBALAMIN; FOLIC ACID; HOMOCYSTEINE; PROTEIN C;

EID: 78149235775     PISSN: 03759393     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (11)

References (25)
  • 1
    • 0033590515 scopus 로고    scopus 로고
    • Treating patients with severe sepsis
    • Wheeler A P, Bernard GR. Treating patients with severe sepsis. N Engl J Med 1999;340:207-14.
    • (1999) N Engl J Med , vol.340 , pp. 207-214
    • Wheeler, A.P.1    Bernard, G.R.2
  • 2
    • 37549020378 scopus 로고    scopus 로고
    • Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008
    • Dellinger R P, Levy MM, Carlet JM, Bion J, Parker MM, Jaeschke R et al. Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008. Crit Care Med 2008;36:296-327.
    • (2008) Crit Care Med , vol.36 , pp. 296-327
    • Dellinger, R.P.1    Levy, M.M.2    Carlet, J.M.3    Bion, J.4    Parker, M.M.5    Jaeschke, R.6
  • 4
    • 69149088637 scopus 로고    scopus 로고
    • Effects of recombinant human activated protein C on the fibrinolytic system of patients undergoing conventional or tight glycemic control
    • Polli F, Savioli M, Cugno M, Taccone P, Bellani G, Spanu P et al. Effects of recombinant human activated protein C on the fibrinolytic system of patients undergoing conventional or tight glycemic control. Minerva Anestesiol 2009;75:417-26.
    • (2009) Minerva Anestesiol , vol.75 , pp. 417-426
    • Polli, F.1    Savioli, M.2    Cugno, M.3    Taccone, P.4    Bellani, G.5    Spanu, P.6
  • 5
    • 35649015324 scopus 로고    scopus 로고
    • Vascular biology in sepsis: Pathophys-iological and therapeutic significance of vascular dysfunction
    • Matsuda N, Hattori Y. Vascular biology in sepsis: pathophys-iological and therapeutic significance of vascular dysfunction. J Smooth Muscle Res 2007;43:117-37.
    • (2007) J Smooth Muscle Res , vol.43 , pp. 117-137
    • Matsuda, N.1    Hattori, Y.2
  • 7
    • 2942726193 scopus 로고    scopus 로고
    • Importance of hemostatic gene polymorphisms for susceptibility to and outcome of severe sepsis
    • Texereau J, Pene F, Chiche JD, Rousseau C, Mira J P. Importance of hemostatic gene polymorphisms for susceptibility to and outcome of severe sepsis. Crit Care Med 2004; 32:S313-S9.
    • (2004) Crit Care Med , vol.32
    • Texereau, J.1    Pene, F.2    Chiche, J.D.3    Rousseau, C.4    Mira, J.P.5
  • 8
    • 34250333053 scopus 로고    scopus 로고
    • Hyperhomocysteinemia and thrombosis. An overview
    • Eldibany ME, Caprini JA. Hyperhomocysteinemia and thrombosis. An overview. Arch Pathol Lab Med 2007;131:872-84.
    • (2007) Arch Pathol Lab Med , vol.131 , pp. 872-884
    • Eldibany, M.E.1    Caprini, J.A.2
  • 9
    • 0022472013 scopus 로고
    • Activation of endogenous factor V by homocysteine-induced vascular endothelial cell activator
    • Rodgers GM, Kane WH. Activation of endogenous factor V by homocysteine-induced vascular endothelial cell activator. J Clin Invest 1986;77:1909-16.
    • (1986) J Clin Invest , vol.77 , pp. 1909-1916
    • Rodgers, G.M.1    Kane, W.H.2
  • 10
    • 0025190042 scopus 로고
    • Homocysteine, an atherogenic stimulus, reduces protein C activation by arterial and venous endothelial cells
    • Rodgers GM, Conn MT. Homocysteine, an atherogenic stimulus, reduces protein C activation by arterial and venous endothelial cells. Blood 1990;75:895-901.
    • (1990) Blood , vol.75 , pp. 895-901
    • Rodgers, G.M.1    Conn, M.T.2
  • 11
    • 0026345948 scopus 로고
    • Inhibition of thrombomodulin surface expression and protein C activation by the thrombogenic agent homocysteine
    • Lentz SR, Sadler JE. Inhibition of thrombomodulin surface expression and protein C activation by the thrombogenic agent homocysteine J Clin Invest 1991;88:1906-14.
    • (1991) J Clin Invest , vol.88 , pp. 1906-1914
    • Lentz, S.R.1    Sadler, J.E.2
  • 12
    • 0026773724 scopus 로고
    • An atherogenic stimulus, homocysteine inhibits cofactor activity of thrombomodulin and enhances thrombomodulin expression in human umbilical vein endothelial cells
    • Hayashi TG, Honda G, Suzuki K. An atherogenic stimulus, homocysteine inhibits cofactor activity of thrombomodulin and enhances thrombomodulin expression in human umbilical vein endothelial cells. Blood 1992;79:2930-6.
    • (1992) Blood , vol.79 , pp. 2930-2936
    • Hayashi, T.G.1    Honda, G.2    Suzuki, K.3
  • 13
    • 0027250615 scopus 로고
    • Homocysteine, a risk factor for premature vascular and thrombosis, induces tissue factor activity in endothelial cells
    • Fryer RH, Wilson BD, Gubler BD, Fitzgerald LA, Rodgers GM. Homocysteine, a risk factor for premature vascular and thrombosis, induces tissue factor activity in endothelial cells. Arterioscler Thromb 1993;13:1327-33.
    • (1993) Arterioscler Thromb , vol.13 , pp. 1327-1333
    • Fryer, R.H.1    Wilson, B.D.2    Gubler, B.D.3    Fitzgerald, L.A.4    Rodgers, G.M.5
  • 14
    • 0036847628 scopus 로고    scopus 로고
    • Association between increased homo-cysteine levels and impaired fibrinolytic potential; potential mechanism for cardiovascular risk
    • Tofler GH, D'Agostino RB, Jacques PF, Bostom AG, Wilson PW, Lipinska I et al. Association between increased homo-cysteine levels and impaired fibrinolytic potential; potential mechanism for cardiovascular risk. Thromb Haemost 2002; 88:799-804.
    • (2002) Thromb Haemost , vol.88 , pp. 799-804
    • Tofler, G.H.1    D'agostino, R.B.2    Jacques, P.F.3    Bostom, A.G.4    Wilson, P.W.5    Lipinska, I.6
  • 17
    • 0030953866 scopus 로고    scopus 로고
    • Interrelation of hyperhomocyst(e)inemia, factor V Leiden, and risk of future venous thromboembolism
    • Ridker PM, Hennekens CH, Selhub J, Miletich J P, Malinow MR. Interrelation of hyperhomocyst(e)inemia, factor V Leiden, and risk of future venous thromboembolism. Circulation 1997;95:1777-82.
    • (1997) Circulation , vol.95 , pp. 1777-1782
    • Ridker, P.M.1    Hennekens, C.H.2    Selhub, J.3    Miletich, J.P.4    Malinow, M.R.5
  • 18
    • 0035830874 scopus 로고    scopus 로고
    • Homocysteine inhibits inactivation of factor Va by activated protein C
    • Undas A, Williams EB, Butenas S, Orfeo T, Mann KG. Homocysteine inhibits inactivation of factor Va by activated protein C. J Biol Chem 2001;276:4389-97.
    • (2001) J Biol Chem , vol.276 , pp. 4389-4397
    • Undas, A.1    Williams, E.B.2    Butenas, S.3    Orfeo, T.4    Mann, K.G.5
  • 19
    • 0032497941 scopus 로고    scopus 로고
    • Common methylenetetrahydrofolate reductase gene mutation leads to hyperhomocysteinemia but not to vascular disease: The result of a meta-analysis
    • Brattstrom L, Wilcken DE, Ohrvik J, Brudin L. Common methylenetetrahydrofolate reductase gene mutation leads to hyperhomocysteinemia but not to vascular disease: the result of a meta-analysis. Circulation 1998;98:2520-6.
    • (1998) Circulation , vol.98 , pp. 2520-2526
    • Brattstrom, L.1    Wilcken, D.E.2    Ohrvik, J.3    Brudin, L.4
  • 22
    • 33745046171 scopus 로고    scopus 로고
    • Mutations and polymorphisms in genes affecting hemostasis proteins and homocysteine metabolism in children with arterial ischemic stroke
    • Komitopoulou A, Platokouki H, Kapsimali Z, Pergantou H, Adamtziki E, Aronis S. Mutations and polymorphisms in genes affecting hemostasis proteins and homocysteine metabolism in children with arterial ischemic stroke. Cerebrovasc Dis 2006;22:13-20.
    • (2006) Cerebrovasc Dis , vol.22 , pp. 13-20
    • Komitopoulou, A.1    Platokouki, H.2    Kapsimali, Z.3    Pergantou, H.4    Adamtziki, E.5    Aronis, S.6
  • 23
    • 69149086176 scopus 로고    scopus 로고
    • Procalcitonin's role in the sepsis cascade. Is procalcitonin a sepsis marker or mediator
    • Dahaba AA, Metzler H. Procalcitonin's role in the sepsis cascade. Is procalcitonin a sepsis marker or mediator? Minerva Anestesiol 2009;75:447-52.
    • (2009) Minerva Anestesiol , vol.75 , pp. 447-452
    • Dahaba, A.A.1    Metzler, H.2
  • 24
    • 72249114039 scopus 로고    scopus 로고
    • Expression of monocyte human leukocyte antigen-DR in relation with sepsis severity and plasma mediators
    • Payen D, Faivre V, Lukaszewicz AC, Villa F, Goldberg P. Expression of monocyte human leukocyte antigen-DR in relation with sepsis severity and plasma mediators. Minerva Anestesiol 2009;75:484-93.
    • (2009) Minerva Anestesiol , vol.75 , pp. 484-493
    • Payen, D.1    Faivre, V.2    Lukaszewicz, A.C.3    Villa, F.4    Goldberg, P.5
  • 25
    • 3042536588 scopus 로고    scopus 로고
    • Plasma HC concentration is not associated with activated protein C resistance in patients investigated for hypercoagulability
    • Zarychanski R, Houston SD. Plasma HC concentration is not associated with activated protein C resistance in patients investigated for hypercoagulability. Thrombosis Haemostasis 2004;916:1115-22.
    • (2004) Thrombosis Haemostasis , vol.916 , pp. 1115-1122
    • Zarychanski, R.1    Houston, S.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.